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  • Open Access

    ARTICLE

    Multi Chunk Learning Based Auto Encoder for Video Anomaly Detection

    Xiaosha Qi1, Genlin Ji2,*, Jie Zhang2, Bo Sheng3

    Intelligent Automation & Soft Computing, Vol.33, No.3, pp. 1861-1875, 2022, DOI:10.32604/iasc.2022.027182 - 24 March 2022

    Abstract Video anomaly detection is essential to distinguish abnormal events in large volumes of surveillance video and can benefit many fields such as traffic management, public security and failure detection. However, traditional video anomaly detection methods are unable to accurately detect and locate abnormal events in real scenarios, while existing deep learning methods are likely to omit important information when extracting features. In order to avoid omitting important features and improve the accuracy of abnormal event detection and localization, this paper proposes a novel method called Multi Chunk Learning based Skip Connected Convolutional Auto Encoder (MCSCAE).… More >

  • Open Access

    ARTICLE

    Image Masking and Enhancement System for Melanoma Early Stage Detection

    Fikret Yalcinkaya*, Ali Erbas

    Intelligent Automation & Soft Computing, Vol.33, No.3, pp. 1961-1977, 2022, DOI:10.32604/iasc.2022.024961 - 24 March 2022

    Abstract Early stage melanoma detection (ESMD) is crucial as late detection kills. Computer aided diagnosis systems (CADS) integrated with high level algorithms are major tools capable of ESMD with high degree of accuracy, specificity, and sensitivity. CADS use the image and the information within the pixels of the image. Pixels’ characteristics and orientations determine the colour and shapes of the images as the pixels and associated environment are closely interrelated with the lesion. CADS integrated with Convolutional Neural Networks (CNN) specifically play a major role for ESMD with high degree of accuracy. The proposed system has… More >

  • Open Access

    ARTICLE

    PAPR Reduction of NOMA Using Vandermonde Matrix-Particle Transmission Sequence

    Arun Kumar1,*, Sandeep Gupta2, Himanshu Sharma3, Mehedi Masud4

    Computer Systems Science and Engineering, Vol.43, No.1, pp. 193-201, 2022, DOI:10.32604/csse.2022.023991 - 23 March 2022

    Abstract Non-Orthogonal Multiple Access (NOMA) is an ideal choice for 5G waveforms due to their characteristics such as high data rate, massive device connectivity, high spectral access, and effective frequency selective fading. Thus, it permits gigantic connectivity. The spectrum overlaps with NOMA, which consents several operators to segment the spectrum at the same frequency. These features make NOMA more suitable for use beyond 5G. Peak to Average Power (PAPR) is a major problem in Multi-Carrier Techniques (MCT) like NOMA and it also degrades the performance of the amplifier. The Partial Transmission Sequence (PTS) is a superior… More >

  • Open Access

    ARTICLE

    Identification of key long noncoding RNAs and their biological functions in hepatocellular carcinoma

    FEI CHEN1,2, LIANG WANG3,*, YUHONG LI1,2,*

    BIOCELL, Vol.46, No.7, pp. 1687-1696, 2022, DOI:10.32604/biocell.2022.018078 - 17 March 2022

    Abstract Long noncoding RNAs (lncRNAs) are vital regulators in tumorigenesis and metastasis. However, the pathological role of lncRNAs in hepatocellular carcinoma (HCC) is still unclear. In this study, we filtered out three lncRNAs from The Cancer Genome Atlas (TCGA) data that were screened for basic expression and clinical research. We selected lncRNA-NEAT1 for further study to explore its function in HCC progression and its regulatory mechanism. We identified three differentially expressed lncRNAs (DElncRNAs) in tumor and adjacent normal tissues from the TCGA library using data mining methods: lncRNA-NEAT1, lncRNA-MAGI2-AS3 and lncRNA-HCG11. Their basic expression levels were… More >

  • Open Access

    ARTICLE

    Anomaly Detection for Internet of Things Cyberattacks

    Manal Alanazi*, Ahamed Aljuhani

    CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 261-279, 2022, DOI:10.32604/cmc.2022.024496 - 24 February 2022

    Abstract The Internet of Things (IoT) has been deployed in diverse critical sectors with the aim of improving quality of service and facilitating human lives. The IoT revolution has redefined digital services in different domains by improving efficiency, productivity, and cost-effectiveness. Many service providers have adapted IoT systems or plan to integrate them as integral parts of their systems’ operation; however, IoT security issues remain a significant challenge. To minimize the risk of cyberattacks on IoT networks, anomaly detection based on machine learning can be an effective security solution to overcome a wide range of IoT… More >

  • Open Access

    ARTICLE

    An Adaptive Classifier Based Approach for Crowd Anomaly Detection

    Sofia Nishath, P. S. Nithya Darisini*

    CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 349-364, 2022, DOI:10.32604/cmc.2022.023935 - 24 February 2022

    Abstract Crowd Anomaly Detection has become a challenge in intelligent video surveillance system and security. Intelligent video surveillance systems make extensive use of data mining, machine learning and deep learning methods. In this paper a novel approach is proposed to identify abnormal occurrences in crowded situations using deep learning. In this approach, Adaptive GoogleNet Neural Network Classifier with Multi-Objective Whale Optimization Algorithm are applied to predict the abnormal video frames in the crowded scenes. We use multiple instance learning (MIL) to dynamically develop a deep anomalous ranking framework. This technique predicts higher anomalous values for abnormal More >

  • Open Access

    ARTICLE

    Melanoma Identification Through X-ray Modality Using Inception-v3 Based Convolutional Neural Network

    Saad Awadh Alanazi*

    CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 37-55, 2022, DOI:10.32604/cmc.2022.020118 - 24 February 2022

    Abstract Melanoma, also called malignant melanoma, is a form of skin cancer triggered by an abnormal proliferation of the pigment-producing cells, which give the skin its color. Melanoma is one of the skin diseases, which is exceptionally and globally dangerous, Skin lesions are considered to be a serious disease. Dermoscopy-based early recognition and detection procedure is fundamental for melanoma treatment. Early detection of melanoma using dermoscopy images improves survival rates significantly. At the same time, well-experienced dermatologists dominate the precision of diagnosis. However, precise melanoma recognition is incredibly hard due to several factors: low contrast between… More >

  • Open Access

    ARTICLE

    Ensemble Deep Learning Models for Mitigating DDoS Attack in Software-Defined Network

    Fatmah Alanazi*, Kamal Jambi, Fathy Eassa, Maher Khemakhem, Abdullah Basuhail, Khalid Alsubhi

    Intelligent Automation & Soft Computing, Vol.33, No.2, pp. 923-938, 2022, DOI:10.32604/iasc.2022.024668 - 08 February 2022

    Abstract Software-defined network (SDN) is an enabling technology that meets the demand of dynamic, adaptable, and manageable networking architecture for the future. In contrast to the traditional networks that are based on a distributed control plane, the control plane of SDN is based on a centralized architecture. As a result, SDNs are susceptible to critical cyber attacks that exploit the single point of failure. A distributed denial of service (DDoS) attack is one of the most crucial and risky attacks, targeting the SDN controller and disrupting its services. Several researchers have proposed signature-based DDoS mitigation and… More >

  • Open Access

    REVIEW

    Biomedical overview of melanin. 2. Updating molecular modeling, synthesis mechanism, and supramolecular properties regarding melanoma therapy

    JUAN CARLOS STOCKERT1,2,*, ALFONSO BLÁZQUEZ-CASTRO3

    BIOCELL, Vol.46, No.6, pp. 1391-1415, 2022, DOI:10.32604/biocell.2022.019493 - 07 February 2022

    Abstract

    Melanins represent one of the most ancient and important group of natural macromolecular pigments. They have multiple biological roles in almost all organisms across the Phyla, examples being photoprotection, anti-oxidative action, radical scavenger activity, and heavy metal removal. From the biomedical point of view, melanocytes are involved in the origin of melanoma tumors, and the main therapeutic advances for their treatment have been revised in Part 1 of this review. The chemical structure of eumelanin is a biological concern of great importance, and therefore, exploring theoretical molecular models and synthesis mechanisms will be here described, as

    More >

  • Open Access

    ARTICLE

    Murine double minute gene 2 (MDM2) promoted hepatocellular carcinoma (HCC) cell growth by targeting fructose-1,6-bisphosphatase (FBP1) for degradation

    YAO XU1,#, BIN WU2,#, JING YANG3, SHENG ZHANG2, LONGGEN LIU4, SUOBAO XU2,*, JIAKAI JIANG2,*

    BIOCELL, Vol.46, No.6, pp. 1483-1491, 2022, DOI:10.32604/biocell.2022.017745 - 07 February 2022

    Abstract To study the roles and association of murine double minute gene 2 (MDM2) and fructose-1,6-biphosphatase (FBP1) in human hepatocellular carcinoma (HCC), growth response of human HCC cells was assessed using proliferation and apoptosis assay. Pro-survival AKT signaling associated proteins (p-AKT, survivin and cleaved caspase 3) were assessed using western blotting. The correlation between MDM2 and FBP1 was assessed using co-immunoprecipitation combined with ubiquitination assay. Our data suggested that low expression of FBP1 was correlated with high levels of MDM2 in HCC cell lines (Huh7 and Hep3B). Overexpression of FBP1 resulted in anti-proliferation, pro-apoptosis, the up-regulation… More >

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