Lv Ling^1,#, Minying Lu^2,#, Ling Ye³, Yuanhang Chen², Sheng Lin², Jun Yang², Yu Rong^2,*, Guixiong Wu^4,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069889 - 30 December 2025

Abstract Background: A significant proportion of patients still cannot benefit from existing targeted therapies and immunotherapies, making the search for new treatment strategies extremely urgent. In this study, we combined integrate public data analysis with experimental validation to identify novel prognostic biomarkers and therapeutic targets for lung adenocarcinoma (LUAD). Methods: We analyzed RNA and protein databases to assess the expression levels of cytochrome C oxidase 5B (COX5B) in LUAD. Several computational algorithms were employed to investigate the relationship between COX5B and immune infiltration in LUAD. To further elucidate the role of COX5B in LUAD, we utilized… More > Graphic Abstract

Xiangmei Ye^1,2,3, Baoyi Yang⁴, Xin Zhang⁵, Luyuan Yang¹, Likun Zhang⁵, Qin Ren¹, Xiaobing Li¹, Leiguang Feng¹, Lanlan Wei^3,6,7,*, Peng Song¹, Yuqing Ye⁸, Xin Lian⁹, Yujuan Gao⁹, Haidi Tang¹, Zhiyu Liu¹

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068814 - 30 December 2025

Abstract Objectives: Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia and Philadelphia-like B-cell acute lymphoblastic leukemia (Ph+/Ph-like ALL) constitute the majority of relapsed/refractory B-ALL (R/R B-ALL) cases, highlighting an urgent need to discover new therapeutic targets. This study aims to elucidate the mechanisms underlying poor prognosis in Ph+/Ph-like ALL through transcriptome sequencing and functional cytological assays, with the goal of informing new clinical treatment strategies. Results: Transcriptomic analysis of Ph+/Ph-like ALL patients revealed that low expression of P2X Purinoceptor 1 (P2RX1) was associated with unfavorable outcomes. Specifically, patients with poor prognosis and low P2RX1 expression exhibited downregulation of… More >

Nadezhda Golubkina^1,*, Pavel Poluboyarinov², Lyubov Skrypnik³, Agnieszka Sękara⁴, Otilia Cristina Murariu⁵, Gianluca Caruso⁶

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3861-3877, 2025, DOI:10.32604/phyton.2025.070988 - 29 December 2025

Abstract Circadian biorhythms are fundamental in plant adaptability and development. To reveal the effect of organic and inorganic forms of Se, foliar treatments of dandelion with 0.26 mM Se solutions were practiced in two contrasting day times: in the morning with the highest levels of leaf Se and polyphenol (TP) and the lowest dry matter, and in the evening with the opposite characteristics. Compared to the control, the morning Se supply demonstrated a higher increase of root biomass (1.27–1.37 times), Se (1.82–2.85 times), TP content (1.42–1.44 times), and antioxidant activity (AOA) (1.47–1.48 times) than the evening… More > Graphic Abstract

Ghinwa Al Mimar¹, Natrah Kamaruzaman^1,*, Kamil Talib Alkhateeb²

Frontiers in Heat and Mass Transfer, Vol.23, No.6, pp. 1933-1956, 2025, DOI:10.32604/fhmt.2025.070118 - 31 December 2025

Abstract The pivotal role microchannels play in the thermal management of electronic components has, in recent decades, prompted extensive research into methods for enhancing their heat transfer performance. Among these methods, surface wettability modification was found to be highly effective owing to its significant influence on boiling dynamics and heat transfer mechanisms. In this study, we modified surface wettability using a nanocomposite coating composed of graphene nano plate (GNPs) and multi-walled carbon nanotubes (MWCNT) and then examined how the modification affected the transfer of boiling heat in microchannels. The resultant heat transfer coefficients for hydrophilic and… More >

Woo-Gyun Choi, Byung Joo Kim^*

BIOCELL, Vol.49, No.12, pp. 2365-2375, 2025, DOI:10.32604/biocell.2025.072715 - 24 December 2025

Abstract Objectives: Petasites japonicus (PJ) is a traditional medicinal herb widely used in East Asia for treating diverse ailments. However, its anticancer properties and underlying mechanisms have not been elucidated. This study investigated the anticancer potential and molecular mechanisms of the methanol extract of Petasites japonicus (PJE) in human adenocarcinoma gastric stomach (AGS) cells. Methods: AGS cells were treated with various concentrations of PJE, and cell viability was measured using MTT and CCK-8 assays. Apoptotic cell death was evaluated by the cell cycle, caspase-3 and -9 activity assays, and western blotting. To elucidate the underlying signaling mechanisms, we… More >

Hauwau Kaoje^1,2, Adekunle Adeleke^2,3,*, Esther Anosike-Francis^2,3, Seun Jesuloluwa^2,3, Temitayo Ogedengbe^2,3, Hauwa Rasheed², Jude Okolie⁴

Journal of Renewable Materials, Vol.13, No.12, pp. 2375-2430, 2025, DOI:10.32604/jrm.2025.02025-0109 - 23 December 2025

Abstract The increasing need for sustainable energy and the environmental impacts of reliance on fossil fuels have sparked greater interest in biomass as a renewable energy source. This review provides an in-depth assessment of bio-oil and biochar generation through the pyrolysis of sawdust, a significant variety of lignocellulosic biomass. The paper investigates different thermochemical conversion methods, including fast, slow, catalytic, flash, and co-pyrolysis, while emphasizing their operational parameters, reactor designs, and effects on product yields. The influence of temperature, heating rate, and catalysts on enhancing the quality and quantity of bio-oil and biochar is thoroughly analyzed. More > Graphic Abstract

Maryam^1,*, Rahayu Puji², Luthfi Muhammad Zulfikar², Ikhsandy Ferry², Nadiyah Khairun¹, Hidayat³, Ilyas Rushdan Ahmad⁴, Syafri Edi⁵

Journal of Renewable Materials, Vol.13, No.12, pp. 2431-2451, 2025, DOI:10.32604/jrm.2025.02024-0063 - 23 December 2025

Abstract The development of the bioplastics industry addresses critical issues such as environmental pollution and food safety concerns. However, the industrialization of bioplastics remains underdeveloped due to challenges such as high production costs and suboptimal material characteristics. To enhance these characteristics, this study investigates bioplastics reinforced with Nanocrystalline Cellulose (NCC) derived from Oil Palm Empty Fruit Bunches (OPEFB), incorporating dispersing agents. The research employs a Central Composite Design from the Response Surface Methodology (RSM) with two factors: the type of dispersing agent (KCl and NaCl) and the NCC concentration from OPEFB (1%–5%), along with the dispersing… More >

G. Hao^*, Z. Chen, R. Xian, W. Yifan

Chalcogenide Letters, Vol.22, No.3, pp. 255-260, 2025, DOI:10.15251/CL.2025.223.255

Abstract In present work, Cu₂BaSnS₄(CBTS) nanoparticles are reported solvothermally synthesized. The formation of single-phase trigonal structure of CBTS nanoparticles is confirmed by XRD and Raman spectroscopic analysis. SEM studies reveal that CBTS exhibits flower shaped structure self-assembling by nanosheets with uniform average thickness 30nm. CBTS materials show abroad absorption in the complete visible range, providing a band-gap value of 1.58eV, indicating potential applications in photocvoltaics. The excellent MB degradation efficiency of 93% under visible light within 100min is achieved, suggesting CBTS is a potential material for effective solar light photocatalytic application. Meanwhile, electrical properties are measured up More >

A. M. Abdel-Daiem^a, M. Ahmed^a,, E. R. Shaaban^b,

Chalcogenide Letters, Vol.22, No.2, pp. 131-142, 2025, DOI:10.15251/CL.2025.222.131

Abstract This paper investigates the impact of reduced graphene oxide (rGO) addition on the structural and optical properties of ZnS nanocomposites. The study began with the synthesis of graphene oxide (GO) through the oxidation of natural graphite powder. This process involved using potassium permanganate in a mixture of sulfuric and phosphoric acids, maintained at 50°C for 48 hours. The reaction was terminated using hydrogen peroxide, followed by purification and drying, yielding 1.5 grams of GO. The preparation of ZnS/GO nanocomposites involved dissolving zinc acetate and varying quantities of GO in water, adjusting the pH, and incorporating… More >

L. Gahramanli^a,b,c,*, M. Muradov^a, G. Eyvazova^a, A. Karimova^a, M. Jafarov^b

Chalcogenide Letters, Vol.22, No.2, pp. 109-121, 2025, DOI:10.15251/CL.2025.222.109

Abstract The study presents nanocomposite materials based on Cd_xZn_1-xS, synthesized as thin films and nanoparticles through two distinct techniques—sonochemical and SILAR synthesis techniques. The characteristics of these materials were investigated using X-ray diffraction (XRD), Ultraviolet spectroscopy (UV-Vis), Fourier-transform infrared (FTIR) spectroscopy, and Scanning Electron Microscopy (SEM). In the sonochemical approach, samples were prepared with three different stabilizers for comparative analysis to determine influence of type of the stabilizers. Meanwhile, the SILAR approach created thin layers with different components (distinctive x value-Cd_xZn_1-xS) at various grown temperatures utilizing polyvinyl alcohol (PVA) as a substrate. At the same time, nanocomposite More >