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  • Open Access

    ARTICLE

    A Deep Learning Framework for Mass-Forming Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma Classification Based on Magnetic Resonance Imaging

    Luda Chen1, Kuangzhu Bao2, Ying Chen2, Jingang Hao2,*, Jianfeng He1,3,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 409-427, 2024, DOI:10.32604/cmc.2024.048507

    Abstract Pancreatic diseases, including mass-forming chronic pancreatitis (MFCP) and pancreatic ductal adenocarcinoma (PDAC), present with similar imaging features, leading to diagnostic complexities. Deep Learning (DL) methods have been shown to perform well on diagnostic tasks. Existing DL pancreatic lesion diagnosis studies based on Magnetic Resonance Imaging (MRI) utilize the prior information to guide models to focus on the lesion region. However, over-reliance on prior information may ignore the background information that is helpful for diagnosis. This study verifies the diagnostic significance of the background information using a clinical dataset. Consequently, the Prior Difference Guidance Network (PDGNet) is proposed, merging decoupled lesion… More >

  • Open Access

    ARTICLE

    Prediction of Ground Vibration Induced by Rock Blasting Based on Optimized Support Vector Regression Models

    Yifan Huang1, Zikang Zhou1,2, Mingyu Li1, Xuedong Luo1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3147-3165, 2024, DOI:10.32604/cmes.2024.045947

    Abstract Accurately estimating blasting vibration during rock blasting is the foundation of blasting vibration management. In this study, Tuna Swarm Optimization (TSO), Whale Optimization Algorithm (WOA), and Cuckoo Search (CS) were used to optimize two hyperparameters in support vector regression (SVR). Based on these methods, three hybrid models to predict peak particle velocity (PPV) for bench blasting were developed. Eighty-eight samples were collected to establish the PPV database, eight initial blasting parameters were chosen as input parameters for the prediction model, and the PPV was the output parameter. As predictive performance evaluation indicators, the coefficient of determination (R2), root mean square… More >

  • Open Access

    ARTICLE

    A Normalizing Flow-Based Bidirectional Mapping Residual Network for Unsupervised Defect Detection

    Lanyao Zhang1, Shichao Kan2, Yigang Cen3, Xiaoling Chen1, Linna Zhang1,*, Yansen Huang4,5

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1631-1648, 2024, DOI:10.32604/cmc.2024.046924

    Abstract Unsupervised methods based on density representation have shown their abilities in anomaly detection, but detection performance still needs to be improved. Specifically, approaches using normalizing flows can accurately evaluate sample distributions, mapping normal features to the normal distribution and anomalous features outside it. Consequently, this paper proposes a Normalizing Flow-based Bidirectional Mapping Residual Network (NF-BMR). It utilizes pre-trained Convolutional Neural Networks (CNN) and normalizing flows to construct discriminative source and target domain feature spaces. Additionally, to better learn feature information in both domain spaces, we propose the Bidirectional Mapping Residual Network (BMR), which maps sample features to these two spaces… More > Graphic Abstract

    A Normalizing Flow-Based Bidirectional Mapping Residual Network for Unsupervised Defect Detection

  • Open Access

    ARTICLE

    The anti-neoplastic effects of metformin modulate the acquired phenotype of fibroblast cells in the breast cancer-normal fibroblast co-culture system

    SAMANEH MOSTAFAVI, ZUHAIR MOHAMMAD HASSAN*

    Oncology Research, Vol.32, No.3, pp. 477-487, 2024, DOI:10.32604/or.2023.043926

    Abstract Intracellular communications between breast cancer and fibroblast cells were reported to be involved in cancer proliferation, growth, and therapy resistance. The hallmarks of cancer-fibroblast interactions, consisting of caveolin 1 (Cav1) and mono-carboxylate transporter 4 (MCT4) (metabolic coupling markers), along with IL-6, TGFβ, and lactate secretion, are considered robust biomarkers predicting recurrence and metastasis. In order to promote a novel phenotype in normal fibroblasts, we predicted that breast cancer cells could be able to cause loss of Cav1 and increase of MCT4, as well as elevate IL-6 and TGFβ in nearby normal fibroblasts. We created a co-culture model using breast cancer… More >

  • Open Access

    RETRACTION

    Retraction: Psychological Support for Public-Funded Normal Students Engaged in Teaching Profession

    Shize Zhi1,2,*

    International Journal of Mental Health Promotion, Vol.26, No.1, pp. 81-81, 2024, DOI:10.32604/ijmhp.2024.049077

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    A Railway Fastener Inspection Method Based on Abnormal Sample Generation

    Shubin Zheng1,3, Yue Wang2, Liming Li2,3,*, Xieqi Chen2,3, Lele Peng2,3, Zhanhao Shang2

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 565-592, 2024, DOI:10.32604/cmes.2023.043832

    Abstract Regular fastener detection is necessary to ensure the safety of railways. However, the number of abnormal fasteners is significantly lower than the number of normal fasteners in real railways. Existing supervised inspection methods have insufficient detection ability in cases of imbalanced samples. To solve this problem, we propose an approach based on deep convolutional neural networks (DCNNs), which consists of three stages: fastener localization, abnormal fastener sample generation based on saliency detection, and fastener state inspection. First, a lightweight YOLOv5s is designed to achieve fast and precise localization of fastener regions. Then, the foreground clip region of a fastener image… More >

  • Open Access

    ARTICLE

    Improving Federated Learning through Abnormal Client Detection and Incentive

    Hongle Guo1,2, Yingchi Mao1,2,*, Xiaoming He1,2, Benteng Zhang1,2, Tianfu Pang1,2, Ping Ping1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 383-403, 2024, DOI:10.32604/cmes.2023.031466

    Abstract Data sharing and privacy protection are made possible by federated learning, which allows for continuous model parameter sharing between several clients and a central server. Multiple reliable and high-quality clients must participate in practical applications for the federated learning global model to be accurate, but because the clients are independent, the central server cannot fully control their behavior. The central server has no way of knowing the correctness of the model parameters provided by each client in this round, so clients may purposefully or unwittingly submit anomalous data, leading to abnormal behavior, such as becoming malicious attackers or defective clients.… More >

  • Open Access

    ARTICLE

    Nuclei Segmentation in Histopathology Images Using Structure-Preserving Color Normalization Based Ensemble Deep Learning Frameworks

    Manas Ranjan Prusty1, Rishi Dinesh2, Hariket Sukesh Kumar Sheth2, Alapati Lakshmi Viswanath2, Sandeep Kumar Satapathy2,3,*

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3077-3094, 2023, DOI:10.32604/cmc.2023.042718

    Abstract This paper presents a novel computerized technique for the segmentation of nuclei in hematoxylin and eosin (H&E) stained histopathology images. The purpose of this study is to overcome the challenges faced in automated nuclei segmentation due to the diversity of nuclei structures that arise from differences in tissue types and staining protocols, as well as the segmentation of variable-sized and overlapping nuclei. To this extent, the approach proposed in this study uses an ensemble of the UNet architecture with various Convolutional Neural Networks (CNN) architectures as encoder backbones, along with stain normalization and test time augmentation, to improve segmentation accuracy.… More >

  • Open Access

    ARTICLE

    Adaptive Multi-Feature Fusion for Vehicle Micro-Motor Noise Recognition Considering Auditory Perception

    Ting Zhao1, Weiping Ding1, Haibo Huang1, Yudong Wu1,2,*

    Sound & Vibration, Vol.57, pp. 133-153, 2023, DOI:10.32604/sv.2023.044203

    Abstract The deployment of vehicle micro-motors has witnessed an expansion owing to the progression in electrification and intelligent technologies. However, some micro-motors may exhibit design deficiencies, component wear, assembly errors, and other imperfections that may arise during the design or manufacturing phases. Consequently, these micro-motors might generate anomalous noises during their operation, consequently exerting a substantial adverse influence on the overall comfort of drivers and passengers. Automobile micro-motors exhibit a diverse array of structural variations, consequently leading to the manifestation of a multitude of distinctive auditory irregularities. To address the identification of diverse forms of abnormal noise, this research presents a… More > Graphic Abstract

    Adaptive Multi-Feature Fusion for Vehicle Micro-Motor Noise Recognition Considering Auditory Perception

  • Open Access

    ARTICLE

    Analysis of differentially expressed genes in Verruca vulgaris vs. adjacent normal skin by RNA-sequencing

    QINGQING GUO1,2, JIAYUE QI1,2, XIAOQIANG LIANG2, ZIGANG ZHAO2, JIA BAI2, FANG XIE2,#,*, CHENGXIN LI1,2,#,*

    BIOCELL, Vol.47, No.11, pp. 2435-2443, 2023, DOI:10.32604/biocell.2023.043126

    Abstract Introduction: Verruca vulgaris is one of the most common low-risk HPV infections and is characterized by excessive proliferation of keratinocytes. Currently, very little genetic information is available regarding verruca vulgaris in the Chinese population. This study aimed to obtain comprehensive transcript information of verruca vulgaris by RNA sequencing. Methods: High-throughput sequencing was performed on three fresh verruca vulgaris samples and adjacent normal skin on the Illumina sequencing platform. The transcriptomes were analyzed using bioinformatics and the differentially expressed genes (DEGs) were verified by immunohistochemistry. Verruca vulgaris exhibited a unique molecular signature. Results: In total, 1,643 DEGs were identified in verruca… More >

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