Sandra Kałużna^1,*, Monika Świerczewska^1,2, Sylwia Ciesiółka¹, Małgorzata Partyka¹, Michał Nowicki¹, Karolina Wojtowicz¹

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070356 - 30 December 2025

Abstract The last research focuses on the role of exosomes in cancer treatment. Exosomes are extracellular vesicles. They can be secreted by cancer cells, and they can modulate chemotherapy sensitivity. Determining exosomal content opens the possibility for guiding treatment strategies for cancer diseases. Exosomal microRNA are considered one of the prime candidates for exosomal biomarkers. Exosomal circular RNAs represent excellent biomarkers for liquid biopsy because of their stability in many types of cancer. Exosomal proteins remain reliable biomarkers also. Exosomes have emerged as promising therapeutic candidates. Their biological properties render them ideal vectors for drug delivery.… More >

Hongyu Wang¹, Wenwu Cui¹, Kai Cui¹, Zixuan Meng^2,*, Bin Li², Wei Zhang¹, Wenwen Li¹

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.069576 - 27 December 2025

Abstract To achieve low-carbon regulation of electric vehicle (EV) charging loads under the “dual carbon” goals, this paper proposes a coordinated scheduling strategy that integrates dynamic carbon factor prediction and multi-objective optimization. First, a dual-convolution enhanced improved Crossformer prediction model is constructed, which employs parallel 1 × 1 global and 3 × 3 local convolution modules (Integrated Convolution Block, ICB) for multi-scale feature extraction, combined with an Adaptive Spectral Block (ASB) to enhance time-series fluctuation modeling. Based on high-precision predictions, a carbon-electricity cost joint optimization model is further designed to balance economic, environmental, and grid-friendly objectives.… More > Graphic Abstract

Shaojie Min¹, Yaxiao Luo¹, Kebing Liu¹, Qingyuan Gong², Yang Chen^1,*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-23, 2026, DOI:10.32604/cmc.2025.073175 - 09 December 2025

Abstract User identity linkage (UIL) across online social networks seeks to match accounts belonging to the same real-world individual. This cross-platform mapping enables accurate user modeling but also raises serious privacy risks. Over the past decade, the research community has developed a wide range of UIL methods, from structural embeddings to multimodal fusion architectures. However, corresponding adversarial and defensive approaches remain fragmented and comparatively understudied. In this survey, we provide a unified overview of both mapping and anti-mapping methods for UIL. We categorize representative mapping models by learning paradigm and data modality, and systematically compare them… More >

Dike Chen^1,2,3, Zhiyong Qin², Ji Zhang², Hongyuan Wang^1,2,*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-17, 2026, DOI:10.32604/cmc.2025.072494 - 09 December 2025

Abstract To address the challenges of small target detection and significant scale variations in unmanned aerial vehicle (UAV) aerial imagery, which often lead to missed and false detections, we propose Multi-scale Feature Fusion YOLO (MFF-YOLO), an enhanced algorithm based on YOLOv8s. Our approach introduces a Multi-scale Feature Fusion Strategy (MFFS), comprising the Multiple Features C2f (MFC) module and the Scale Sequence Feature Fusion (SSFF) module, to improve feature integration across different network levels. This enables more effective capture of fine-grained details and sequential multi-scale features. Furthermore, we incorporate Inner-CIoU, an improved loss function that uses auxiliary More >

Zilin Zhang¹, Yan Liu^1,*, Jia Liu², Senbao Hou³, Yuping Zhang¹, Chenyuan Wang¹

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-14, 2026, DOI:10.32604/cmc.2025.072286 - 09 December 2025

Abstract With the growing demand for more comprehensive and nuanced sentiment understanding, Multimodal Sentiment Analysis (MSA) has gained significant traction in recent years and continues to attract widespread attention in the academic community. Despite notable advances, existing approaches still face critical challenges in both information modeling and modality fusion. On one hand, many current methods rely heavily on encoders to extract global features from each modality, which limits their ability to capture latent fine-grained emotional cues within modalities. On the other hand, prevailing fusion strategies often lack mechanisms to model semantic discrepancies across modalities and to… More >

Zhonghao Wang^1,2, Xin Liu^1,2,*, Changhua Yue³, Haiwen Yuan⁴

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-23, 2026, DOI:10.32604/cmc.2025.071813 - 09 December 2025

Abstract To address critical challenges in nighttime ship detection—high small-target missed detection (over 20%), insufficient lightweighting, and limited generalization due to scarce, low-quality datasets—this study proposes a systematic solution. First, a high-quality Night-Ships dataset is constructed via CycleGAN-based day-night transfer, combined with a dual-threshold cleaning strategy (Laplacian variance sharpness filtering and brightness-color deviation screening). Second, a Cross-stage Lightweight Fusion-You Only Look Once version 8 (CLF-YOLOv8) is proposed with key improvements: the Neck network is reconstructed by replacing Cross Stage Partial (CSP) structure with the Cross Stage Partial Multi-Scale Convolutional Block (CSP-MSCB) and integrating Bidirectional Feature Pyramid More >

Ans D. Alghamdi^*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-35, 2026, DOI:10.32604/cmc.2025.071210 - 09 December 2025

Abstract Multimodal dialogue systems often fail to maintain coherent reasoning over extended conversations and suffer from hallucination due to limited context modeling capabilities. Current approaches struggle with cross-modal alignment, temporal consistency, and robust handling of noisy or incomplete inputs across multiple modalities. We propose MultiAgent-Chain of Thought (CoT), a novel multi-agent chain-of-thought reasoning framework where specialized agents for text, vision, and speech modalities collaboratively construct shared reasoning traces through inter-agent message passing and consensus voting mechanisms. Our architecture incorporates self-reflection modules, conflict resolution protocols, and dynamic rationale alignment to enhance consistency, factual accuracy, and user engagement. More >

Muhammad Adil¹, Nadeem Javaid^1,*, Imran Ahmed², Abrar Ahmed³, Nabil Alrajeh^4,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-20, 2026, DOI:10.32604/cmc.2025.071215 - 10 November 2025

Abstract Heart disease remains a leading cause of mortality worldwide, emphasizing the urgent need for reliable and interpretable predictive models to support early diagnosis and timely intervention. However, existing Deep Learning (DL) approaches often face several limitations, including inefficient feature extraction, class imbalance, suboptimal classification performance, and limited interpretability, which collectively hinder their deployment in clinical settings. To address these challenges, we propose a novel DL framework for heart disease prediction that integrates a comprehensive preprocessing pipeline with an advanced classification architecture. The preprocessing stage involves label encoding and feature scaling. To address the issue of… More >

Thierry Mugenzi, Cahit Perkgoz^*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-21, 2026, DOI:10.32604/cmc.2025.070381 - 10 November 2025

Abstract Missing data presents a crucial challenge in data analysis, especially in high-dimensional datasets, where missing data often leads to biased conclusions and degraded model performance. In this study, we present a novel autoencoder-based imputation framework that integrates a composite loss function to enhance robustness and precision. The proposed loss combines (i) a guided, masked mean squared error focusing on missing entries; (ii) a noise-aware regularization term to improve resilience against data corruption; and (iii) a variance penalty to encourage expressive yet stable reconstructions. We evaluate the proposed model across four missingness mechanisms, such as Missing… More >

Lincong Zhang¹, Yuqing Liu¹, Kefeng Wei², Weinan Zhao¹, Bo Qian^1,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-18, 2026, DOI:10.32604/cmc.2025.069108 - 10 November 2025

Abstract In the field of edge computing, achieving low-latency computational task offloading with limited resources is a critical research challenge, particularly in resource-constrained and latency-sensitive vehicular network environments where rapid response is mandatory for safety-critical applications. In scenarios where edge servers are sparsely deployed, the lack of coordination and information sharing often leads to load imbalance, thereby increasing system latency. Furthermore, in regions without edge server coverage, tasks must be processed locally, which further exacerbates latency issues. To address these challenges, we propose a novel and efficient Deep Reinforcement Learning (DRL)-based approach aimed at minimizing average… More >