Tsu-Yang Wu¹, Chengyuan Yu¹, Yanan Zhao², Saru Kumari³, Chien-Ming Chen^1,*

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.069139 - 12 January 2026

Abstract With the increasing complexity of logistics operations, traditional static vehicle routing models are no longer sufficient. In practice, customer demands often arise dynamically, and multi-depot systems are commonly used to improve efficiency. This paper first introduces a vehicle routing problem with the goal of minimizing operating costs in a multi-depot environment with dynamic demand. New customers appear in the delivery process at any time and are periodically optimized according to time slices. Then, we propose a scheduling system TS-DPU based on an improved ant colony algorithm TS-ACO to solve this problem. The classical ant colony More >

Oncology Research Editorial Office

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.077268 - 30 December 2025

Abstract This article has no abstract. More >

Sandra Kałużna^1,*, Monika Świerczewska^1,2, Sylwia Ciesiółka¹, Małgorzata Partyka¹, Michał Nowicki¹, Karolina Wojtowicz¹

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070356 - 30 December 2025

Abstract The last research focuses on the role of exosomes in cancer treatment. Exosomes are extracellular vesicles. They can be secreted by cancer cells, and they can modulate chemotherapy sensitivity. Determining exosomal content opens the possibility for guiding treatment strategies for cancer diseases. Exosomal microRNA are considered one of the prime candidates for exosomal biomarkers. Exosomal circular RNAs represent excellent biomarkers for liquid biopsy because of their stability in many types of cancer. Exosomal proteins remain reliable biomarkers also. Exosomes have emerged as promising therapeutic candidates. Their biological properties render them ideal vectors for drug delivery.… More >

Marija Macenić, Tomislav Kurevija^*, Tin Herbst

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.067067 - 27 December 2025

Abstract The increased interest in geothermal energy is evident, along with the exploitation of traditional hydrothermal systems, in the growing research and projects developing around the reuse of already-drilled oil, gas, and exploration wells. The Republic of Croatia has around 4000 wells, however, due to a long period since most of these wells were drilled and completed, there is uncertainty about how many are available for retrofitting as deep-borehole heat exchangers. Nevertheless, as hydrocarbon production decreases, it is expected that the number of wells available for the revitalization and exploitation of geothermal energy will increase. The… More >

Chang Su, Liangliang Zhao^*, Dongbing Xiang

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-24, 2026, DOI:10.32604/cmc.2025.071319 - 09 December 2025

Abstract To address low learning efficiency and inadequate path safety in spraying robot navigation within complex obstacle-rich environments—with dense, dynamic, unpredictable obstacles challenging conventional methods—this paper proposes a hybrid algorithm integrating Q-learning and improved A*-Artificial Potential Field (A-APF). Centered on the Q-learning framework, the algorithm leverages safety-oriented guidance generated by A-APF and employs a dynamic coordination mechanism that adaptively balances exploration and exploitation. The proposed system comprises four core modules: (1) an environment modeling module that constructs grid-based obstacle maps; (2) an A-APF module that combines heuristic search from A* algorithm with repulsive force strategies from… More >

Fang Liu^*, Xianghui Meng, Jiachen Li, Sibo Guo

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-21, 2026, DOI:10.32604/cmc.2025.069243 - 09 December 2025

Abstract With the popularization of smart devices, Location-Based Services (LBS) greatly facilitates users’ life, but at the same time brings the risk of users’ location privacy leakage. Existing location privacy protection methods are deficient, failing to reasonably allocate the privacy budget for non-outlier location points and ignoring the critical location information that may be contained in the outlier points, leading to decreased data availability and privacy exposure problems. To address these problems, this paper proposes a Mix Location Privacy Preservation Method Based on Differential Privacy with Clustering (MLDP). The method first utilizes the DBSCAN clustering algorithm… More >

Zhenpeng Jiang, Qingquan Liu^*, Ende Wang

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-18, 2026, DOI:10.32604/cmc.2025.068780 - 10 November 2025

Abstract Rapidly-exploring Random Tree (RRT) and its variants have become foundational in path-planning research, yet in complex three-dimensional off-road environments their uniform blind sampling and limited safety guarantees lead to slow convergence and force an unfavorable trade-off between path quality and traversal safety. To address these challenges, we introduce HS-APF-RRT*, a novel algorithm that fuses layered sampling, an enhanced Artificial Potential Field (APF), and a dynamic neighborhood-expansion mechanism. First, the workspace is hierarchically partitioned into macro, meso, and micro sampling layers, progressively biasing random samples toward safer, lower-energy regions. Second, we augment the traditional APF by More >

Luksamee Vittaya^1,*, Chakhriya Chalad¹, Sittichoke Janyong², Nararak Leesakul³

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4091-4115, 2025, DOI:10.32604/phyton.2025.074891 - 29 December 2025

Abstract Calophyllum inophyllum is a tropical plant that could have useful medicinal properties for pharmaceutical and cosmetic applications. The present study extracted the flower, fruit, leaf, twig, and bark of the plant by maceration in different organic solvents. The correlation between bioactive compounds and their biological activities was investigated, with emphasis on their therapeutic relevance through in silico pharmacokinetic predictions using SwissADME. Qualitative and quantitative analyses were conducted to determine the total phenolic, flavonoid, and saponin contents of the extracts. Spectral analysis of the extracts revealed –OH, C=O, C=C, and C–H functional groups. The antioxidant activity of the… More > Graphic Abstract

Tai Liu^1,#, Huichun Xu^1,#, Sikandar Amanullah^2,*, Ye Che¹, Ling Zhang¹, Zeyu Jiang¹, Weiyi Bi¹, Lei Zhu¹, Di Wang^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4117-4137, 2025, DOI:10.32604/phyton.2025.074131 - 29 December 2025

Abstract Heavy metal accumulation in agricultural soil is primarily driven by pesticides, polluted water, and industrial gas emissions, which pose threats to sustainable crop production. Chromium (Cr) stress has an adverse impact on plant development and metabolism, but approaches to reduce its toxicity and enhance plant resistance remain limited. Melatonin is a potent antioxidant involved in regulating various morpho-physiological functions of plants under different abiotic stresses. In this study, we investigated the impact of exogenous melatonin to mitigate the negative effects of potassium dichromate (PD) stress in melon plants and analyzed genetic modulation of morphological, physiological,… More >

Abd Al Karim Jaafar¹, Suleiman Salim¹, Dema Altheb¹, Mukhtar Iderawumi Abdulraheem^2,3, Andrés Rodríguez-Seijo^4,5,*

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3945-3960, 2025, DOI:10.32604/phyton.2025.072520 - 29 December 2025

Abstract The use of organic fertilizers can be an opportunity to increase crop yield and improve soil fertility in semi-arid regions, since soils from these regions usually have unfavourable conditions for plant growth. This research investigates the effects of organic and mineral fertilization on the impact of soil properties (pH, electrical conductivity and organic matter), availability of macro- (N, P and K), micro-nutrients (Fe, Mn, Cu and Zn) and the accumulation of heavy metals (Pb, Cd, Cr) in soil and potato tubers grown under semiarid conditions. A field experiment was conducted in Raqqa Governorate (Syria) using… More >