Hsiao-Chun Han¹, Der-Chen Huang^1,*, Chin-Ling Chen^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 67-126, 2025, DOI:10.32604/cmes.2025.070944 - 30 October 2025

Abstract This study presents a systematic review of applications of artificial intelligence (abbreviated as AI) and blockchain in supply chain provenance traceability and legal forensics cover five sectors: integrated circuits (abbreviated as ICs), pharmaceuticals, electric vehicles (abbreviated as EVs), drones (abbreviated as UAVs), and robotics—in response to rising trade tensions and geopolitical conflicts, which have heightened concerns over product origin fraud and information security. While previous literature often focuses on single-industry contexts or isolated technologies, this review comprehensively surveys these sectors and categorizes 116 peer-reviewed studies by application domain, technical architecture, and functional objective. Special attention More >

Xiaobing Li^1,2, Yongsheng Liu¹, Limin Wei¹, Li Rao¹, Jingxin Mao^1,*, Xuemei Li^3,*

BIOCELL, Vol.49, No.5, pp. 813-832, 2025, DOI:10.32604/biocell.2025.062124 - 27 May 2025

Abstract Yeast-based models have become a powerful platform in pharmaceutical research, offering significant potential for producing complex drugs, vaccines, and therapeutic agents. While many current drugs were discovered before fully understanding their molecular mechanisms, yeast systems now provide valuable insights for drug discovery and personalized medicine. Recent advancements in genetic engineering, metabolic engineering, and synthetic biology have improved the efficiency and scalability of yeast-based production systems, enabling more sustainable and cost-effective manufacturing processes. This paper reviews the latest developments in yeast-based technologies, focusing on their use as model organisms to study disease mechanisms, identify drug targets,… More >

MAURA BENEDETTI, MARIA ELISA GIULIANI, MARICA MEZZELANI, ALESSANDRO NARDI, LUCIA PITTURA, STEFANIA GORBI, FRANCESCO REGOLI

BIOCELL, Vol.46, No.1, pp. 37-49, 2022, DOI:10.32604/biocell.2022.017507 - 28 September 2021

Abstract Oxidative stress is a critical condition derived from the imbalance between the generation of reactive oxygen species and the sophisticated network of antioxidant mechanisms. Several pollutants and environmental factors can affect this system through connected mechanisms, indirect relationships, and cascade effects from pre-transcriptional to catalytic level, by either enhancing intracellular ROS formation or impairing antioxidant defenses. This review summarizes the current knowledge on the pro-oxidant challenges from emerging environmental stressors threatening marine organisms, such as pharmaceuticals, microplastics and climate-related ocean changes. Emphasis will be placed on oxidative pathways, including signaling proteins and transcription factors involved More >

Danaé Samara Sánchez-Sandoval^#, Omar González-Ortega^#, Mara Fernanda Navarro-Martínez, Juan Marcos Castro-Tapia, Ramón Fernando García de la Cruz, Ruth Elena Soria-Guerra^*

Phyton-International Journal of Experimental Botany, Vol.90, No.5, pp. 1519-1533, 2021, DOI:10.32604/phyton.2021.015087 - 27 May 2021

Abstract The emerging contaminants (ECs) are organic compounds including pharmaceuticals. These products are consumed in large quantities, favoring their continuous entrance to the environment and affecting the health of living beings. Diclofenac is a non-steroidal anti-inflammatory drug with analgesic properties of prolonged release. It is the commonest postoperative analgesic, and it is highly consumed without prescription. In recent years, the capability of microalgae to remove pharmaceuticals in water has been tested as a promising tool. In this work, the removal efficiency of diclofenac (16 µg/mL) by the microalga Nannochloropsis oculata CCAP 186/7 was evaluated. The major nutrient… More >

Robert B. Den^1,2,3, Laura A. Doyle², Karen E. Knudsen^1,2,3,4

Canadian Journal of Urology, Vol.21, Suppl.2, pp. 70-76, 2014

Abstract instruction: Introduction: Bone-seeking radiopharmaceuticals have been used for decades in the palliation of pain from bone metastases emerging from prostate cancer. Recent clinical evidence has demonstrated an improved survival in men with metastatic castration-resistant prostate cancer (CRPC) with radium-223.
instruction: Materials and methods: A review of the literature was performed to identify the role of radiopharmaceuticals in the management of prostate cancer. We focused on prospective trials in order to identify the highest level of evidence describing this therapy. Further, we focused on providing a clinical guide for the use of radium-223.
instruction: Results: The phase III ALSYMPCA… More >