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  • Open Access

    ARTICLE

    Performance Study of Dynamic Intake and Exhaust Façades in Hot and Dry Climates: Iraq Case Study

    S. M. Hosseinalipour*, S. Asiaei*, Ammar A. Hussain Al-Taee

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 747-767, 2024, DOI:10.32604/fhmt.2024.051541

    Abstract This paper is part of a series addressing the urgent need for effective technologies to reduce energy demand and mitigate climate impact. This study focused on the implementation and development of dynamic insulation technology for a sustainable and energy-efficient future in the region, especially in Iraq. The study assessed the energy efficiency of dynamic insulation technology by analyzing three wall models (static, dynamic, and modified) during the winter season. This paper expands the analysis to include a hot, dry summer scenario, providing valuable insights into the year-round performance of dynamic walls and enabling sustainable and More >

  • Open Access

    ARTICLE

    Revealing the role of honokiol in human glioma cells by RNA-seq analysis

    YUNBAO GUO1,#, XU LIU1,#, QI XU2, XIAOTONG ZHOU3, JIAWEI LIU3, YANYAN XU2, YAN LU2,*, HAIYAN LIU2,*

    BIOCELL, Vol.48, No.6, pp. 945-958, 2024, DOI:10.32604/biocell.2024.049748

    Abstract Background: Glioma is a kind of tumor that easily deteriorates and originates from glial cells in nerve tissue. Honokiol is a bisphenol compound that is an essential monomeric compound extracted from the roots and bark of Magnoliaceae plants. It also has anti-infection, antitumor, and immunomodulatory effects. In this study, we found that honokiol induces cell apoptosis in the human glioma cell lines U87-MG and U251-MG. However, the mechanism through which honokiol regulates glioma cell apoptosis is still unknown. Methods: We performed RNA-seq analysis of U251-MG cells treated with honokiol and control cells. Protein-protein interaction (PPI)… More > Graphic Abstract

    Revealing the role of honokiol in human glioma cells by RNA-seq analysis

  • Open Access

    ARTICLE

    RNA Interference of IQ Motif Containing GTPase-Activating Protein 3 (IQGAP3) Inhibits Cell Proliferation and Invasion in Breast Carcinoma Cells

    Gaowu Hu*, Ye Xu*, Wenquan Chen*, Jiandong Wang, Chunying Zhao†1, Ming Wang*1

    Oncology Research, Vol.24, No.6, pp. 455-461, 2016, DOI:10.3727/096504016X14685034103635

    Abstract Breast cancer is a highly prevalent disease affecting women. The association of IQ motif containing GTPaseactivating protein 3 (IQGAP3) and breast cancer is poorly defined. Here we reported that IQGAP3 is a key regulator of cell proliferation and metastasis during breast cancer progression. The expression of IQGAP3 was significantly increased in breast tissues compared to nontumor tissues at both protein and mRNA levels. Furthermore, IQGAP3 had a high expression level in ZR-75-30 and BT474 compared to other breast cancer cell lines. Depletion of IQGAP3 through RNA interference in ZR-75-30 and BT474 significantly inhibited cell proliferation. More >

  • Open Access

    ARTICLE

    PAQR3 Inhibits the Proliferation and Tumorigenesis in Esophageal Cancer Cells

    Fang Zhou*1, Shunchang Wang†1, Jianjun Wang*

    Oncology Research, Vol.25, No.5, pp. 663-671, 2017, DOI:10.3727/096504016X14761384026719

    Abstract Progestin and adipoQ receptor family member III (PAQR3), a member of the PAQR family, is frequently downregulated in different types of human cancer. However, its expression and functions in esophageal cancer are still unknown. This study aimed to explore the expression of PAQR3 in esophageal cancer cell lines and to investigate the role of PAQR3 in the development of esophageal cancer. Our data showed that PAQR3 is expressed in low amounts in human esophageal cancer cell lines. Overexpression of PAQR3 significantly suppressed the proliferation, migration, and invasion of esophageal cancer cells. In addition, overexpression of More >

  • Open Access

    ARTICLE

    A Deep Reinforcement Learning-Based Technique for Optimal Power Allocation in Multiple Access Communications

    Sepehr Soltani1, Ehsan Ghafourian2, Reza Salehi3, Diego Martín3,*, Milad Vahidi4

    Intelligent Automation & Soft Computing, Vol.39, No.1, pp. 93-108, 2024, DOI:10.32604/iasc.2024.042693

    Abstract For many years, researchers have explored power allocation (PA) algorithms driven by models in wireless networks where multiple-user communications with interference are present. Nowadays, data-driven machine learning methods have become quite popular in analyzing wireless communication systems, which among them deep reinforcement learning (DRL) has a significant role in solving optimization issues under certain constraints. To this purpose, in this paper, we investigate the PA problem in a -user multiple access channels (MAC), where transmitters (e.g., mobile users) aim to send an independent message to a common receiver (e.g., base station) through wireless channels. To… More >

  • Open Access

    ARTICLE

    Le projet Sav-AQ : étude des freins et facteurs à l’utilisation d’un site internet dédié aux patientes atteintes de cancer du sein, l’exemple de la Nouvelle-Aquitaine

    Valérie Berger1,2,*, Hélène Hoarau1,2, Florence Saillour3,4

    Psycho-Oncologie, Vol.17, No.3, pp. 159-166, 2023, DOI:10.32604/po.2023.044727

    Abstract Le développement des plateformes numériques dans le domaine de la santé transforme les interactions soignants-soignés et la diffusion des savoirs. S’informer par le biais d’internet est devenu une habitude pour de nombreux patients et doit être pris en compte par les soignants. Ainsi, comprendre les usages des outils numériques par les patients est un enjeu de santé publique. L’étude Sav-AQ vise à comprendre les usages par des femmes atteintes d’un cancer du sein et le rôle des professionnels de santé. Il s’agit d’une étude mixte de faisabilité exploratoire, de type avant-après l’intégration dans le parcours… More >

  • Open Access

    ARTICLE

    ScRNA-seq reveals the correlation between M2 phenotype of tumor-associated macrophages and lymph node metastasis of breast cancer

    JUN SHEN1,#, HONGFANG MA2,#, YONGXIA CHEN3, JIANGUO SHEN1,*

    Oncology Research, Vol.31, No.6, pp. 955-966, 2023, DOI:10.32604/or.2023.029638

    Abstract The process of lymphatic metastasis was proved to be associated with podoplanin-expressing macrophages in breast cancer (BC). This study aimed to investigate the role of the M2 phenotype of tumor-associated macrophages and mine the key M2 macrophages-related genes for lymph node metastasis in BC. We downloaded the GSE158399 dataset from the Gene Expression Omnibus (GEO) database, which includes transcriptomic profiles of individual cells from primary tumors, negative lymph nodes (NLNs), and positive lymph nodes (PLNs) of breast cancer patients. The cell subsets were identified by clustering analysis after quality control of the scRNA-seq using Seurat.… More >

  • Open Access

    ARTICLE

    Suitability and Sustainability of Rainwater Quality Monitoring System in Cistern for Domestic Use

    Kenedy A. Greyson*

    Journal on Internet of Things, Vol.5, pp. 1-11, 2023, DOI:10.32604/jiot.2023.040255

    Abstract Rainwater harvesting (RWH) systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries. However, due to various reasons, there are several sources of contamination in the rainwater cistern systems. Dissolved chemicals from the roofing, storage, and conveyance materials, together with the suspended particulate matter from the airborne, are examples of water contamination. In this work, the water quality monitoring system has been designed and implemented. Chemical and physical parameters of water samples were collected from three locations using a data acquisition (DAQ) system and More >

  • Open Access

    ARTICLE

    New Configurations of the Fuzzy Fractional Differential Boussinesq Model with Application in Ocean Engineering and Their Analysis in Statistical Theory

    Yu-Ming Chu1, Saima Rashid2,*, Shazia Karim3, Anam Sultan2

    CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.2, pp. 1573-1611, 2023, DOI:10.32604/cmes.2023.027724

    Abstract The fractional-order Boussinesq equations (FBSQe) are investigated in this work to see if they can effectively improve the situation where the shallow water equation cannot directly handle the dispersion wave. The fuzzy forms of analytical FBSQe solutions are first derived using the Adomian decomposition method. It also occurs on the sea floor as opposed to at the functionality. A set of dynamical partial differential equations (PDEs) in this article exemplify an unconfined aquifer flow implication. This methodology can accurately simulate climatological intrinsic waves, so the ripples are spread across a large demographic zone. The Aboodh… More >

  • Open Access

    ARTICLE

    Improved Control in Single Phase Inverter Grid-Tied PV System Using Modified PQ Theory

    Nur Fairuz Mohamed Yusof1, Dahaman Ishak2, Muhammad Ammirrul Atiqi Mohd Zainuri3,*, Muhammad Najwan Hamidi2, Zuhair Muhammed Alaas4, Mohamed Mostafa Ramadan Ahmed5

    Intelligent Automation & Soft Computing, Vol.37, No.2, pp. 2441-2457, 2023, DOI:10.32604/iasc.2023.037778

    Abstract Grid-connected reactive-load compensation and harmonic control are becoming a central topic as photovoltaic (PV) grid-connected systems diversified. This research aims to produce a high-performance inverter with a fast dynamic response for accurate reference tracking and a low total harmonic distortion (THD) even under nonlinear load applications by improving its control scheme. The proposed system is expected to operate in both stand-alone mode and grid-connected mode. In stand-alone mode, the proposed controller supplies power to critical loads, alternatively during grid-connected mode provide excess energy to the utility. A modified variable step incremental conductance (VS-InCond) algorithm is… More >

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