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  • Open Access

    ARTICLE

    Malware Attacks Detection in IoT Using Recurrent Neural Network (RNN)

    Abeer Abdullah Alsadhan1, Abdullah A. Al-Atawi2, Hanen karamti3, Abid Jameel4, Islam Zada5, Tan N. Nguyen6,*

    Intelligent Automation & Soft Computing, Vol.39, No.2, pp. 135-155, 2024, DOI:10.32604/iasc.2023.041130

    Abstract IoT (Internet of Things) devices are being used more and more in a variety of businesses and for a variety of tasks, such as environmental data collection in both civilian and military situations. They are a desirable attack target for malware intended to infect specific IoT devices due to their growing use in a variety of applications and their increasing computational and processing power. In this study, we investigate the possibility of detecting IoT malware using recurrent neural networks (RNNs). RNN is used in the proposed method to investigate the execution operation codes of ARM-based Internet of Things apps (OpCodes).… More >

  • Open Access

    ARTICLE

    Cardiovascular Disease Prediction Using Risk Factors: A Comparative Performance Analysis of Machine Learning Models

    Adil Hussain1,*, Ayesha Aslam2

    Journal on Artificial Intelligence, Vol.6, pp. 129-152, 2024, DOI:10.32604/jai.2024.050277

    Abstract The diagnosis and prognosis of cardiovascular diseases are critical medical responsibilities that assist cardiologists in correctly classifying patients and treating them accordingly. The utilization of machine learning in the medical domain has witnessed a notable surge due to its ability to discern patterns from vast amounts of data. Machine learning algorithms that can categorize cases of cardiovascular illness may help doctors reduce the number of wrong diagnoses. This research investigates the efficacy of different machine learning algorithms in predicting cardiovascular disease in accordance with risk factors. This study utilizes a variety of machine learning models, including Logistic Regression, Random Forest,… More >

  • Open Access

    CASE REPORT

    Bicuspidization Using the Open-Sleeve Technique for Congenital Aortic Stenosis during Infancy

    Toshi Maeda*, Hiroki Ito, Keiichi Hirose, Kisaburo Sakamoto

    Congenital Heart Disease, Vol.19, No.2, pp. 177-183, 2024, DOI:10.32604/chd.2024.050945

    Abstract Congenital aortic stenosis (cAS) frequently requires intervention during the neonatal or infantile period. However, surgical repair is challenging because of the narrow surgical space. We performed bicuspidization using the open-sleeve technique for cAS with a unicuspid aortic valve in two patients. Postoperatively, the patients were doing well without reintervention for the aortic valve for 8 and 6 years, respectively. Their aortic annular diameter increased along with somatic growth. Bicuspidization for neonates or infancy can be performed safely using the open-sleeve technique as its midterm results have been satisfactory. More > Graphic Abstract

    Bicuspidization Using the Open-Sleeve Technique for Congenital Aortic Stenosis during Infancy

  • Open Access

    REVIEW

    Arterial Duct Stenting Versus Modified Blalock-Taussig Shunt in Patient with Ductal-Dependent Pulmonary Circulation: Systematic Review & Meta-Analysis

    Ketut Putu Yasa1,2,*, Nyoman Satria Sadu Bhaskara2, Putu Febry Krisna Pertiwi2

    Congenital Heart Disease, Vol.19, No.2, pp. 139-156, 2024, DOI:10.32604/chd.2024.050348

    Abstract Objective: Patients with ductal-dependent pulmonary circulation require alternative blood flow to provide and maintain adequate oxygenation. Modified Blalock-Taussig Shunt (MBTS) has been the standard for providing such a result. Currently, less invasive methods such as Arterial Duct (AD) stenting have been performed as alternatives. This study aims to compare the outcome of AD stenting and MBTS. Method: Systematic research was performed in online databases using the PRISMA protocol. The outcomes measured were 30-day mortality, complication, unplanned intervention, oxygen saturation, duration of hospital, and ICU length of stay. Any comparative study provided with full text is included. The outcome of each… More >

  • Open Access

    ARTICLE

    Single-Nucleus RNA Sequencing Reveals Cardiac Macrophage Landscape in Hypoplastic Left Heart Syndrome

    Xiaozhuo Xu1,2, Yilin Huang1,2, Xu Han2,*

    Congenital Heart Disease, Vol.19, No.2, pp. 233-246, 2024, DOI:10.32604/chd.2024.050231

    Abstract Background: Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart diseases in clinical treatment. In cardiac tissues, resident macrophages fulfill critical functions in maintaining a stable cardiac state and have strong regenerative capacity and organ specificity. However, the molecular mechanisms of macrophages in HLHS remained unclear. Methods: Single-nucleus RNA sequencing (snRNA-seq) data of HLHS and healthy control (donors) samples obtained from the Gene Expression Omnibus (GEO) database were normalized and clustered using the Seurat package. The “FindMarkers” function was used to screen differentially expressed genes (DEGs) between the HLHS and donor groups and to analyze the… More > Graphic Abstract

    Single-Nucleus RNA Sequencing Reveals Cardiac Macrophage Landscape in Hypoplastic Left Heart Syndrome

  • Open Access

    EDITORIAL

    Health Systems Strengthening to Tackle the Global Burden of Pediatric and Congenital Heart Disease: A Diagonal Approach

    Dominique Vervoort1,2,3,*, Amy Verstappen3, Sreehari Madhavankutty Nair4, Chong Chin Eu5, Bistra Zheleva3,6

    Congenital Heart Disease, Vol.19, No.2, pp. 131-138, 2024, DOI:10.32604/chd.2024.049814

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    High Prevalence of Anatomical Variations and Anomalies of the Coronary Arteries Detected by CT Angiography in Symptomatic Patients

    Ghazi A. Alshumrani*

    Congenital Heart Disease, Vol.19, No.2, pp. 197-206, 2024, DOI:10.32604/chd.2024.049401

    Abstract Objective: Coronary artery anatomical variations and anomalies are an important topic due to their potential clinical manifestations. This study aims to investigate the prevalence of coronary artery anatomical variations and anomalies in symptomatic patients with coronary computed tomography angiography (CCTA). Methods: This is a retrospective study that included all symptomatic patients who had CCTA in a tertiary care hospital in Saudi Arabia during a period of seven years. Results: The total number of included patients was 507 (60% males) with a mean age of 57.4 years. Approximately 41% had luminal stenoses, averaging 49.7%. The total number of patients with coronary… More >

  • Open Access

    CASE REPORT

    Stubborn Hypoxia in Neonates with D-Transposition of the Great Arteries after Arterial Switch Operation: Central Sleep Apnea as the Cause and Potential Indicator of Brain Immaturity

    Camden L. Hebson1,*, Kyle Bliton2, Amr Y. Hammouda1, Kaitlyn Barr3, W. Hampton Gray4, Mohini Gunnett2, Waldemar F. Carlo1

    Congenital Heart Disease, Vol.19, No.2, pp. 185-195, 2024, DOI:10.32604/chd.2024.048871

    Abstract D-transposition of the great arteries (d-TGA) is surgically repaired with the arterial switch operation (ASO) with excellent results, however short and long-term morbidities still develop including neurocognitive delay. Clinically significant central sleep apnea is uncommon in non-premature infants, but when present indicates immature autonomic control of respiration likely due to a neurologic disorder. We report the unanticipated finding of central sleep apnea in four-term neonates with d-TGA after uncomplicated ASO, with the short-term complication of delayed hospital discharge and long-term concerns regarding this early marker of brain immaturity and its hindrance to normal development. Within this report, we will review… More >

  • Open Access

    REVIEW

    Treatment and Clinical Management of Chronic Thromboembolic Pulmonary Hypertension: An Update of Literature Review

    Yuan Ren1, Yingxian Sun1, Zhiguang Yang2, Yanli Chen1,*

    Congenital Heart Disease, Vol.19, No.2, pp. 157-176, 2024, DOI:10.32604/chd.2024.047930

    Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a chronic, progressive, debilitating, and life-threatening complication of pulmonary embolism (PE). Recent technological advances have permitted various treatment options for the treatment of CTEPH, including surgery, angioplasty, and medical treatment, depending on the location and characteristics of lesions. Pulmonary endarterectomy (PEA) is the treatment of choice for CTEPH, as it offers excellent long-term outcomes and a high probability of recovery. Moreover, various medical and interventional therapies are currently being developed for patients with inoperable CTEPH. This review mainly summarizes the current treatment approaches of CTEPH, offering more options for specialist physicians to, thus, better… More >

  • Open Access

    ARTICLE

    Failure to Rescue as a Quality Metric in Congenital Heart Surgeries in a High-Complexity Service Provider Institution Located in a Middle-Income Country

    Gustavo Cruz1,*, Santiago Pedroza2, Juan F. Vélez3, Jessica Largo2, Juan F. Tejada4, Jorge H. Mejía-Mantilla5

    Congenital Heart Disease, Vol.19, No.2, pp. 207-218, 2024, DOI:10.32604/chd.2024.044244

    Abstract Background: Failure to rescue has been an effective quality metric in congenital heart surgery. Conversely, morbidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with better-quality performance. We aim to measure the complications, mortality, and risk factors in pediatric patients undergoing congenital heart surgery in a high-complexity institution located in a middle-income country and compare it with other institutions that have conducted a similar study. Methods: A retrospective observational study was conducted in a high-complexity service provider institution, in Cali, Colombia. All pediatric patients undergoing any congenital heart surgery between 2019 and 2022 were included.… More >

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