Yong Zhao^1,#, Yaxuan Jiang^3,#, Li Wen¹, Rui Luo², Guorui Li², Jianjun Di², Mingda Yin², Zhiyan Wang², Fenglan Huang^2,4,5,6,7,*, Fanjuan Meng^3,*

Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 713-723, 2024, DOI:10.32604/phyton.2024.047657

Abstract The yield of castor is influenced by the type of inflorescence and the proportion of female flowers. However, there are few studies on the genetic mechanism involved in the development and differentiation of castor inflorescences. In this study, we performed transcriptomic analyses of three different phenotypes of inflorescences at the five-leaf stage. In comparison to the MI (complete pistil without willow leaves), 290 and 89 differentially expressed genes (DEGs) were found in the SFI (complete pistil with willow leaves) and the BI (monoecious inflorescence), respectively. Among the DEGs, 104 and 88 were upregulated in the SFI and BI, respectively, compared… More >

Yushan Yin¹, Witold Pedrycz^1,2, Zhiwu Li^1,*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 623-650, 2024, DOI:10.32604/cmc.2024.048787

Abstract Utilizing granular computing to enhance artificial neural network architecture, a new type of network emerges—the granular neural network (GNN). GNNs offer distinct advantages over their traditional counterparts: The ability to process both numerical and granular data, leading to improved interpretability. This paper proposes a novel design method for constructing GNNs, drawing inspiration from existing interval-valued neural networks built upon NNNs. However, unlike the proposed algorithm in this work, which employs interval values or triangular fuzzy numbers for connections, existing methods rely on a pre-defined numerical network. This new method utilizes a uniform distribution of information granularity to granulate connections with… More >

XUHUI ZHAO^1,2, XIAOMIN HUANG¹, CHUNYAN DANG², XIA WANG¹, YUJIAO QI³, HONGLING LI^2,*

Oncology Research, Vol.32, No.5, pp. 999-1009, 2024, DOI:10.32604/or.2024.046679

Abstract Background: EBV-miR-BARTs exhibit significant relevance in epithelial tumors, particularly in EBV-associated gastric and nasopharyngeal cancers. However, their specific mechanisms in the initiation and progression of gastric cancer remain insufficiently explored. Material and Methods: Initially, EBV-miRNA-BART6-5p and its target gene SMAD4 expression were assessed in EBV-associated gastric cancer tissues and cell lines. Subsequent transfection induced overexpression of EBV-miRNA-BART6-5p in AGS and MKN-45, and downregulation in EBV-positive cells (SUN-719). The subsequent evaluation aimed to observe their impact on gastric cancer cell proliferation, migration, and glycolytic processes, with the TGF-β/SMAD4 signaling pathway value clarified using a TGF-β inhibitor. Results: EBV-miRNA-BART6-5p exhibits pronounced upregulation… More >

Jipeng Xie^1,2, Guolai Yang^1,*, Liqun Wang¹, Lei Li¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 793-819, 2024, DOI:10.32604/cmes.2024.048174

Abstract To enhance the comprehensive performance of artillery internal ballistics—encompassing power, accuracy, and service life—this study proposed a multi-stage multidisciplinary design optimization (MS-MDO) method. First, the comprehensive artillery internal ballistic dynamics (AIBD) model, based on propellant combustion, rotation band engraving, projectile axial motion, and rifling wear models, was established and validated. This model was systematically decomposed into subsystems from a system engineering perspective. The study then detailed the MS-MDO methodology, which included Stage I (MDO stage) employing an improved collaborative optimization method for consistent design variables, and Stage II (Performance Optimization) focusing on the independent optimization of local design variables and… More >

JIA SHAO^1,2, CAN ZHANG², YAONAN TANG², AIQIN HE², WEIPEI ZHU^1,*

BIOCELL, Vol.48, No.4, pp. 571-580, 2024, DOI:10.32604/biocell.2024.049092

Abstract Objective: Previous studies indicated that aberrant circular RNA (circRNA) expression affects gene expression regulatory networks, leading to the aberrant activation of tumor pathways and promoting tumor cell growth. However, the expression, clinical significance, and effects on cell propagation, invasion, and dissemination of circRNA_001896 in cervical cancer (CC) tissues remain unclear. Methods: The Gene Expression Omnibus (GEO) datasets (GSE113696 and GSE102686) were used to examine differential circRNA expression in CC and adjacent tissues. The expression of circRNA_001896 was detected in 72 CC patients using fluorescence quantitative PCR. Correlation analysis with clinical pathological features was performed through COX multivariate and univariate analysis.… More >

BIN LI^1,2,3,#, YUCHENG SHENG^4,#, XIAOYING XU⁴, SHENGCUN WANG³, HONGYAN SONG³, JINGYUAN LI³, HAONAN JI¹, QINGHUA WANG³, XIAODI ZHOU^1,*, LONGJU QI^2,*

BIOCELL, Vol.48, No.4, pp. 601-611, 2024, DOI:10.32604/biocell.2024.047404

Abstract Objective: Chronic kidney disease (CKD) is a progressive disorder characterized by intricate structural and functional alterations in the kidneys, attributable to diverse causative factors. Notably, the therapeutic promise of miR-145-5p in addressing renal pathologies has been discerned. This investigation seeks to elucidate the functional role of miR-145-5p in injured kidneys by subjecting human glomerular mesangial cells (HGMCs) to stimulation with Angiotensin II (AngII). Materials and Methods: Cellular viability and the levels of inflammatory mediators were evaluated utilizing Cell Counting Kit-8 (CCK-8), quantitative real-time polymerase chain reaction (qRT-PCR), and western blot methodologies, both in the presence of AngII incubation and in… More >

GENG SU, YA-JIE JIANG, HONG-BIN JU, YA-KUI WANG, TAO GENG^*

Journal of Polymer Materials, Vol.36, No.4, pp. 293-304, 2019, DOI:10.32381/JPM.2019.36.04.1

Abstract Two kinds of poly quaternary ammonium salts (PQAS) namely PDMC (poly (methacryloxyethyl trimethyl ammonium chloride)), CPAM (methacryloxyethyl trimethyl ammonium chloride / acrylamide copolymer) were prepared. The chemical structures of the PQAS were characterized by Fourier transform infrared (FT-IR), nuclear magnetic resonance (¹ H NMR) spectrum, thermogravimetric analysis (TGA), and scanning electron microscope (SEM). The antibacterial activity of PQAS against three kinds of bacteria and one kind of fungus, was evaluated by the method described in QB/T 2738-2012. Antibacterial tests showed that the antibacterial activity increased with the increase of cationicity and molecular weight on PQAS. It shows the antimicrobial activity… More >

Xiaojie Liang^1,2, Wei An², Yuekun Li², Yajun Wang², Xiaoya Qin², Yanhong Cui¹, Shuchai Su^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.3, pp. 467-486, 2024, DOI:10.32604/phyton.2024.047628

Abstract

Goji berry (Lycium barbarum L.) is substantially dependent on nitrogen fertilizer application, which can significantly enhance fruit yield and Goji berry industrial development in Ningxia, China. This study aimed to analyze the functions of differential nitrogen application rates including low (N1), medium (N2), and high (N3) levels in soil microbial community structure (bacterial and fungal) at 2 diverse soil depths (0–20, 20–40 cm) through high-throughput sequencing technology by targeting 16S RNA gene and ITS1 & ITS2 regions. All the observed physicochemical parameters exhibited significant improvement (p < 0.05) with increased levels of nitrogen and the highest values for most parameters… More >

NURUL HAYATI YUSOF^1,*, DAZYLAH DARJI¹, TAN KIM SONG¹, NGHIEM THI THUONG²

Journal of Polymer Materials, Vol.39, No.1-2, pp. 151-166, 2022, DOI:10.32381/JPM.2022.39.1-2.10

Abstract In this work, a pure gum mould made of prevulcanized natural rubber/cloisite-Na⁺ nanocomposite (PVNR/CN) was prepared and characterized for ornament application. The suitable conditions to prepare PVNR/CN latex mixtures and the properties of the resulting PVNR/CN nanocomposites were investigated. The optimum CN concentration in the latex mixture was 1.0 phr, with the properties of 60 wt% total solid content, more than 600 sec mechanical stability time, lower than 350 cP Brookfield viscosity, and pH 10. The properties of PVNR/CN nanocomposite showed high strength, moderate hardness, and good thermal stability. The morphology by TEM showed well dispersion of CN particles in… More >

SUBRATA PAL^1,2, BHUVNESHWAR RAI¹, AJAY KUMAR TYAGI¹, SUNITA RATTAN², VIRENDRA KUMAR³

Journal of Polymer Materials, Vol.39, No.1-2, pp. 55-70, 2022, DOI:10.32381/JPM.2022.39.1-2.4

Abstract The present work is focused on the study of antimicrobial and water absorption properties of the surface of grafted rayon fiber with quaternary ammonium-based salts containing 3- Acrylamidopropyl trimethyl ammonium chloride (APTAC) monomer induced by gamma radiation. Grafting was qualitatively confirmed by FTIR-ATR,TGA, SEM and by calculating grafting yield and grafting efficiency. The performance was examined for water absorbency and antibacterial efficacy (R) against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Study showed that water absorption, grafting yield and grafting efficiency increased steadily with the increase in monomer concentration and absorbed gamma irradiation dose up to a certain… More >