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  • Open Access


    Crosslinking-mediated activation of the FcεRI: Does it need antigen for success?


    BIOCELL, Vol.46, No.5, pp. 1125-1129, 2022, DOI:10.32604/biocell.2022.018513

    Abstract Mast cells (MCs), hematopoietic cells of the myeloid lineage, are well-known for their pro-inflammatory nature contributing to the development of various allergic and autoimmune diseases. One of the characteristic receptors on MCs, the high-affinity receptor for IgE (FcεRI), is activated in its IgE-bound state via binding and crosslinking by polyvalent antigen. This results in its phosphorylation by the SRC family kinase LYN, initiating differential signaling pathways, eventually triggering immunological effector functions, such as degranulation and cytokine production. Few publications have reported on FcεRI-dependent but antigen-independent MC activation by antibody-mediated crosslinking of membrane molecules (e.g., transmembrane More >

  • Open Access


    The Frequency Selection of SH0 Waves for Total Transmission and Its Application in the Damage Detection of Aircrafts

    Yanchao Yue1, *, Tangbing Chen1, Lingling Zhang1, Moustafa Abdelsalam1, Josephine Musanyufu1

    CMES-Computer Modeling in Engineering & Sciences, Vol.122, No.1, pp. 259-272, 2020, DOI:10.32604/cmes.2020.07218

    Abstract Based on wave interference, a methodology to realize the total transmission phenomenon of SH0 waves is proposed in this paper. After a systematical theoretical investigation, an exact frequency of a flat plate consisting of another medium with finite length, is obtained, which is furthermore exemplified by the finite element method. This frequency is the same as the classical Fabry-Perot condition and dependent on the thickness of the material. It has been revealed that an SH0 wave, with its wavelength equal to twice of the length of another medium, can totally transmit across the medium without… More >

  • Open Access


    Finite Element Analysis for Type B Aortic Dissection Treated with Two Types of Stent Grafts

    Zhuangyuan Meng1, Tao Ma2, Shengzhang Wang1,*, Zhihui Dong2,*, Weiguo Fu2

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 19-21, 2019, DOI:10.32604/mcb.2019.05706

    Abstract This article has no abstract. More >

  • Open Access


    Effects of PEMFs on Patients’ Recovery after Reconstruction with Use of Double-looped Semitendinosus and Gracilis Tendon Grafts: a Multicenter, Prospective, Randomized and Double-blind Study

    R. Cadossi1, L. Massari2, F. Benazzo3, F. Falez4, S. Giannini5, C. Zorzi6, L. Pederzini7, S. Setti1

    Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 239-240, 2006, DOI:10.32604/mcb.2006.003.239

    Abstract This article has no abstract. More >

  • Open Access


    Vibration Isolation for Sensitive Payloads of Spacecrafts Via Stewart Platform With the X-Shape Supporting Structure

    Xin Wang1,*, Xiaokui Yue1, Honghua Dai1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.2, pp. 25-25, 2019, DOI:10.32604/icces.2019.04851

    Abstract With the rapid development of space technologies, the requirements of precise pointing and extreme stability increase a lot for spacecrafts. For some spacecrafts, sensitive payloads, including space telescopes, imaging sensors, space-borne optical interferometers are essential for the missions, which require a relatively quiet working environment. Generally, a spacecraft includes multiple instruments, including reaction wheels, cryogenic coolers, control moment gyroscopes and solar array drives, which can produce micro-vibrations. However, the micro-vibrations from the spacecraft and orbital perturbations both have a serious influence on the performance of sensitive payloads. For the sensitive payloads, performance requirements of low… More >

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