HONGYUAN LIANG^1,#, YANQIU LI^2,#, YONGGANG QU³, LINGYUN ZHANG^4,*

Oncology Research, Vol.32, No.2, pp. 393-407, 2024, DOI:10.32604/or.2023.031134

Abstract Advanced LUAD shows limited response to treatment including immune therapy. With the development of sequencing omics, it is urgent to combine high-throughput multi-omics data to identify new immune checkpoint therapeutic response markers. Using GSE72094 (n = 386) and GSE31210 (n = 226) gene expression profile data in the GEO database, we identified genes associated with lung adenocarcinoma (LUAD) death using tools such as “edgeR” and “maftools” and visualized the characteristics of these genes using the “circlize” R package. We constructed a prognostic model based on death-related genes and optimized the model using LASSO-Cox regression methods. By calculating the cell death… More >

Ying Zhang¹, Wei Li^1,*, Guidong Yang¹, Snezana Kirin²

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2177-2199, 2024, DOI:10.32604/cmes.2023.030728

Abstract The Mean First-Passage Time (MFPT) and Stochastic Resonance (SR) of a stochastic tumor-immune model with noise perturbation are discussed in this paper. Firstly, considering environmental perturbation, Gaussian white noise and Gaussian colored noise are introduced into a tumor growth model under immune surveillance. As follows, the long-time evolution of the tumor characterized by the Stationary Probability Density (SPD) and MFPT is obtained in theory on the basis of the Approximated Fokker-Planck Equation (AFPE). Herein the recurrence of the tumor from the extinction state to the tumor-present state is more concerned in this paper. A more efficient algorithm of Back-Propagation Neural… More >

Abdul Rehman, Dongsun Kim^*, Anand Paul

CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 2289-2307, 2023, DOI:10.32604/cmc.2023.036435

Abstract Disasters such as conflagration, toxic smoke, harmful gas or chemical leakage, and many other catastrophes in the industrial environment caused by hazardous distance from the peril are frequent. The calamities are causing massive fiscal and human life casualties. However, Wireless Sensors Network-based adroit monitoring and early warning of these dangerous incidents will hamper fiscal and social fiasco. The authors have proposed an early fire detection system uses machine and/or deep learning algorithms. The article presents an Intelligent Industrial Monitoring System (IIMS) and introduces an Industrial Smart Social Agent (ISSA) in the Industrial SIoT (ISIoT) paradigm. The proffered ISSA empowers smart… More >

ZHIWANG LI, HAN YU, YUPING LIU, WEISHENG WU, HAIJING ZENG, EN LI^*

BIOCELL, Vol.47, No.11, pp. 2409-2422, 2023, DOI:10.32604/biocell.2023.031186

Abstract Familial adenomatous polyposis (FAP) is an autosomal dominant disease with a high probability of becoming cancerous. Many RNAs potentially associated with FAP have not been identified. In this study, a circRNA (circular RNA) expression profile of FAP was established using a circRNA microarray, and differentially expressed circRNAs were verified by RT-qPCR. The effects of hsa_circ_0036740 on the malignant behavior of tumor cells (proliferation, apoptosis, and epithelial mesenchymal transition) and the levels of C3A complement protein expression were evaluated. Moreover, neutrophils were isolated and co-cultured with colorectal cancer cells (CRCs), followed by measurements of MPO-DNA, citrullinated histone H3, interleukin (IL)-1β, IL-6,… More > Graphic Abstract

Sikandar Khan¹, Khalid Saeed¹, Muhammad Faran Majeed^2,*, Salman A. AlQahtani³, Khursheed Aurangzeb³, Muhammad Shahid Anwar^4,*

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 1303-1323, 2023, DOI:10.32604/cmc.2023.039697

Abstract Delay Tolerant Networks (DTNs) have the major problem of message delay in the network due to a lack of end-to-end connectivity between the nodes, especially when the nodes are mobile. The nodes in DTNs have limited buffer storage for storing delayed messages. This instantaneous sharing of data creates a low buffer/shortage problem. Consequently, buffer congestion would occur and there would be no more space available in the buffer for the upcoming messages. To address this problem a buffer management policy is proposed named “A Novel and Proficient Buffer Management Technique (NPBMT) for the Internet of Vehicle-Based DTNs”. NPBMT combines appropriate-size… More >

Nourmeen Lotfy¹, Abdulaziz Shehab^1,2,*, Mohammed Elhoseny^1,3, Ahmed Abu-Elfetouh¹

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 1227-1249, 2023, DOI:10.32604/cmc.2023.039185

Abstract Despite the extensive effort to improve intelligent educational tools for smart learning environments, automatic Arabic essay scoring remains a big research challenge. The nature of the writing style of the Arabic language makes the problem even more complicated. This study designs, implements, and evaluates an automatic Arabic essay scoring system. The proposed system starts with pre-processing the student answer and model answer dataset using data cleaning and natural language processing tasks. Then, it comprises two main components: the grading engine and the adaptive fusion engine. The grading engine employs string-based and corpus-based similarity algorithms separately. After that, the adaptive fusion… More >

Allam Abumwais^*, Mujahed Eleyat

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 615-632, 2023, DOI:10.32604/cmc.2023.038810

Abstract Recent architectures of multi-core systems may have a relatively large number of cores that typically ranges from tens to hundreds; therefore called many-core systems. Such systems require an efficient interconnection network that tries to address two major problems. First, the overhead of power and area cost and its effect on scalability. Second, high access latency is caused by multiple cores’ simultaneous accesses of the same shared module. This paper presents an interconnection scheme called N-conjugate Shuffle Clusters (NCSC) based on multi-core multi-cluster architecture to reduce the overhead of the just mentioned problems. NCSC eliminated the need for router devices and… More >

Valérie Berger^1,2,*, Hélène Hoarau^1,2, Florence Saillour^3,4

Psycho-Oncologie, Vol.17, No.3, pp. 159-166, 2023, DOI:10.32604/po.2023.044727

Abstract Le développement des plateformes numériques dans le domaine de la santé transforme les interactions soignants-soignés et la diffusion des savoirs. S’informer par le biais d’internet est devenu une habitude pour de nombreux patients et doit être pris en compte par les soignants. Ainsi, comprendre les usages des outils numériques par les patients est un enjeu de santé publique. L’étude Sav-AQ vise à comprendre les usages par des femmes atteintes d’un cancer du sein et le rôle des professionnels de santé. Il s’agit d’une étude mixte de faisabilité exploratoire, de type avant-après l’intégration dans le parcours de soins du portail «… More >

Lihong Guo^*, Jie Yang, Haitao Wu

CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1929-1946, 2023, DOI:10.32604/cmc.2023.039170

Abstract Attribute-based encryption (ABE) is a technique used to encrypt data, it has the flexibility of access control, high security, and resistance to collusion attacks, and especially it is used in cloud security protection. However, a large number of bilinear mappings are used in ABE, and the calculation of bilinear pairing is time-consuming. So there is the problem of low efficiency. On the other hand, the decryption key is not uniquely associated with personal identification information, if the decryption key is maliciously sold, ABE is unable to achieve accountability for the user. In practical applications, shared message requires hierarchical sharing in… More >

Haiming Zhang^1,2,*, Shilin Zhao^1,2, Zhenshan Cui^1,2

The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.08884

Abstract Particle-reinforced aluminum matrix composites (PRAMCs) have great potential for application in aerospace, automobile, defense, and electronics due to their high specific strength and stiffness and good resistance to wear and corrosion. Achieving a superior trade-off between the strength and ductility of PRAMCs necessitates an elaborative control of the microstructures, like the size and distribution of particles, as well as grain size, morphology, and texture of the matrix. The multiscale interaction between the particles and the matrix’s microstructure is insufficiently understood due to the lagging of high-resolved in-situ characterization. This work proposes a nonlocal physically based crystal plasticity (CP) modeling approach… More >