Ernesto Lee¹, Furqan Rustam², Hina Fatima Shahzad², Patrick Bernard Washington³, Abid Ishaq³, Imran Ashraf^4,*

Computer Systems Science and Engineering, Vol.45, No.3, pp. 3053-3077, 2023, DOI:10.32604/csse.2023.029059

Abstract With the increasing usage of drugs to remedy different diseases, drug safety has become crucial over the past few years. Often medicine from several companies is offered for a single disease that involves the same/similar substances with slightly different formulae. Such diversification is both helpful and dangerous as such medicine proves to be more effective or shows side effects to different patients. Despite clinical trials, side effects are reported when the medicine is used by the mass public, of which several such experiences are shared on social media platforms. A system capable of analyzing such reviews could be very helpful… More >

Said Benkirane¹, Azidine Guezzaz¹, Mourade Azrour¹, Akber Abid Gardezi², Shafiq Ahmad³, Abdelaty Edrees Sayed³, Salman Naseer⁴, Muhammad Shafiq^5,*

CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 3781-3794, 2023, DOI:10.32604/cmc.2023.033119

Abstract Today, road safety remains a serious concern for governments around the world. In fact, approximately 1.35 million people die and 2–50 million are injured on public roads worldwide each year. Straight bends in road traffic are the main cause of many road accidents, and excessive and inappropriate speed in this very critical area can cause drivers to lose their vehicle stability. For these reasons, new solutions must be considered to stop this disaster and save lives. Therefore, it is necessary to study this topic very carefully and use new technologies such as Vehicle Ad Hoc Networks (VANET), Internet of Things… More >

Kisaezehra¹, Muhammad Umer Farooq^1,*, Muhammad Aslam Bhutto², Abdul Karim Kazi¹

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 911-927, 2023, DOI:10.32604/iasc.2023.031359

Abstract The construction industry has always remained the economic and social backbone of any country in the world where occupational health and safety (OHS) is of prime importance. Like in other developing countries, this industry pays very little, rather negligible attention to OHS practices in Pakistan, resulting in the occurrence of a wide variety of accidents, mishaps, and near-misses every year. One of the major causes of such mishaps is the non-wearing of safety helmets (hard hats) at construction sites where falling objects from a height are unavoidable. In most cases, this leads to serious brain injuries in people present at… More >

Bing Wang^1,2,*, Zhongxun Li¹, Rui Shi¹, Yuzheng Zhang¹, Yao Yao¹

Energy Engineering, Vol.119, No.6, pp. 2469-2487, 2022, DOI:10.32604/ee.2022.021171

Abstract With policy incentives for the coalbed methane in energy industry, coalbed methane from coal production has been effectively improved by technology innovations in coalbed methane extraction and utilization. The progress of coalbed methane promotes the clean construction of energy system and contributes to carbon neutrality target. To quantitatively measure the contributions of the coalbed methane in energy industry, this paper builds a carbon emissions accounting system for coalbed methane in China and assesses the historical co-benefits of coalbed methane utilization from the aspects of emissions reduction, safety and economy. By using the parameters of gas content, raw coal production, gas… More >

Hanhan Zhang¹, Zhihui Xu², Hong Qian¹, Xiaoyan Su^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.134, No.2, pp. 1005-1019, 2023, DOI:10.32604/cmes.2022.021898

Abstract Failure mode and effects analysis (FMEA) is a widely used safety assessment method in many fields. Z-number was previously applied in FMEA since it can take both possibility and reliability of information into consideration. However, the use of fuzzy weighted mean to integrate Z-valuations may have some drawbacks and is not suitable for some situations. In this paper, an improved method is proposed based on Z-numbers and the graded mean integration representation (GMIR) to deal with the uncertain information in FMEA. First, Z-numbers are constructed based on the evaluations of risk factors O, S, D for each failure mode by… More >

Zhengshu Zhou^*, Yutaka Matsubara, Hiroaki Takada

Computer Systems Science and Engineering, Vol.45, No.1, pp. 35-50, 2023, DOI:10.32604/csse.2023.030848

Abstract Since entering the era of Industry 4.0, the concept of Healthcare 4.0 has also been put forward and explored by researchers. How to use Information Technology (IT) to better serve people’s healthcare is one of the most featured emerging directions in the academic circle. An important field of Healthcare 4.0 research is the reliability engineering of healthcare service. Because healthcare systems often affect the health and even life of their users, developers must be very cautious in the design, development, and operation of these healthcare systems and services. The problems to be solved include the reliability of business process, system… More >

Guodong Liu^1,2,*, Zhijun Zhou¹, Shiqiang Xu¹, Wenjing Mi²

CMES-Computer Modeling in Engineering & Sciences, Vol.133, No.2, pp. 351-375, 2022, DOI:10.32604/cmes.2022.020335

Abstract Water level variations have caused numerous dam slope collapse disasters around the world, illustrating the large influence of water level fluctuations on dam slopes. The required indoor tests were conducted and a numerical model of an actual earth-filled dam was constructed to investigate the influences of the water level fluctuation rate and the hysteresis of the soil–water characteristic curve (SWCC) on the stability of the upstream dam slope. The results revealed that the free surface in the dam body for the desorption SWCC during water level fluctuations was higher than that for the adsorption SWCC, which would be more evident… More >

Hugues Lucron^1,*, Alban-Elouen Baruteau^2,3, Caroline Ovaert⁴, Ali Houeijeh⁵, Mélanie Brard¹, Patrice Guerin², François Bourlon⁶, Claire Dauphin⁷, Saskia Tuttle¹, Maha Tagorti³, Rishika Banydeen⁸, François Godart⁵

Congenital Heart Disease, Vol.17, No.4, pp. 421-436, 2022, DOI:10.32604/chd.2022.020835

Abstract Objectives: We aim to describe the efficacy, safety, and characteristics of the Amplatzer Vascular Plug (AVP) II and IV “off-label” use for multiple cardiovascular occlusions in children under 10 years. Methods: Observational retrospective multicenter (2007–2020, 6 centers) review of paediatric procedures using AVP II or IV. Results: A total of 125 children (49.6% aged ≤ 1 year, 147 lesions) underwent 136 successive procedures (success rate: 98.5%) using 169 devices (109 AVP IV, 60 AVP II). The mean device diameter was 7.7 ± 3.2 mm (4–20 mm). The median AVP size to vessel diameter ratio was 1.3 (0–2). The median age and weight… More > Graphic Abstract

Dariimaa Ganbat^1,2, Bat-Erdene Jugder³, Lkhamaa Ganbat⁴, Miki Tomoeda⁵, Erdenetsogt Dungubat^2,6, Ambaga Miyegombo⁷, Gantsetseg Garmaa⁸, Yoshihisa Takahashi⁶, Ryuji Fukuzawa⁶, Ichiro Mori⁶, Takayuki Shiomi⁶, Akinori Nakata⁹, Yasuhiko Tomita^6,*

Oncologie, Vol.24, No.2, pp. 195-225, 2022, DOI:10.32604/oncologie.2022.022299

Abstract Most cancer cells overexpress the anti-apoptotic protein survivin and display redox dysregulation originating from genotypic and phenotypic alterations. These disturbances contribute to the uncontrolled proliferation, invasion, and chemoresistance of cancer cells, yet they also represent a specific vulnerability that could be exploited therapeutically in selected tumors. YM155 (sepantronium bromide) is a naphthoquinone-containing imidazolebased compound that selectively inhibits survivin expression at the transcriptional and post-transcriptional levels. Here, we performed a systematic review and meta-analysis of clinical studies in which YM155 was administered as monotherapy or combination therapy for patients with cancer. We assessed fully or partially reported clinical outcomes and pharmacological… More >

Yaohong Liu, Wensou Huang, Mingji He, Hui Lian, Yongjian Guo, Jingjun Huang, Jingwen Zhou, Kangshun Zhu

Oncology Research, Vol.27, No.5, pp. 565-573, 2019, DOI:10.3727/096504018X15313896322888

Abstract This study aimed to investigate the efficacy and safety of drug-eluting beads transarterial chemoembolization (DEB-TACE) treatment in Barcelona Clinic Liver Cancer (BCLC) stage C liver cancer patients. In 39 patients with BCLC stage C liver cancer, after the first cycle of DEB-TACE, 2 (5.1%) and 24 (61.5%) patients achieved complete response (CR) and partial response (PR) to give an overall objective response rate (ORR) of 66.7%. With respect to the second cycle of therapy, the ORR was higher in patients receiving DEB-TACE compared with those receiving cTACE (57.1% vs. 11.1%). After the first cycle of DEB-TACE treatment, the percentages of… More >