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  • Open Access

    RETRACTION

    Retraction: Truncated Bid Overexpression Induced by Recombinant Adenovirus Cre/LoxP System Suppresses the Tumorigenic Potential of CD133+ Ovarian Cancer Stem Cells

    Oncology Research Editorial Office

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.077268 - 30 December 2025

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    The Efficacy and Safety of B-Cell Maturation Antigen (BCMA) Antibody-Drug Conjugates (ADC) in Development against Cancer: A Systematic Review

    Jing Shan1, Catherine King2,3, Harunor Rashid3,4, Veysel Kayser1,*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070851 - 30 December 2025

    Abstract Objectives: B-cell maturation antigen (BCMA)-targeted antibody–drug conjugates (ADCs) have emerged as promising therapies for relapsed/refractory multiple myeloma (RRMM), but the overall efficacy and safety profile is unclear. This study aimed to synthesize the available evidence on the safety and efficacy of BCMA-ADCs in development for RRMM. Methods: A systematic search was conducted using six bibliographic databases and ClinicalTrials.gov up to November 2024. Studies were eligible if they were human clinical trials or animal studies evaluating BCMA-ADCs and reported efficacy and safety outcomes. Data extraction and quality assessments were conducted using validated tools, including ROBINS-I… More >

  • Open Access

    REVIEW

    Effectiveness and Safety of Lenvatinib and Everolimus after Immune Checkpoint Inhibitors in Metastatic Renal Cell Cancer: A Systematic Review

    Giacomo Iovane1,*, Luca Traman2, Michele Maffezzoli1,3, Giuseppe Fornarini2, Domenico Corradi4, Debora Guareschi4, Matteo Santoni5,#, Sebastiano Buti1,#

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070523 - 30 December 2025

    Abstract Background: While the treatment of metastatic renal cell carcinoma (mRCC) is evolving due to immune checkpoint inhibitors (ICIs), optimal strategies for later lines of therapy have yet to be defined. The combination of lenvatinib and everolimus represents a viable option, and the present review aimed to summarize its activity, effectiveness, and safety. Methods: A systematic review of the literature was conducted using PubMed, targeting studies published between 2018 and 2025. Eligible studies included English-language prospective and retrospective trials reporting survival outcomes in mRCC patients treated with lenvatinib and everolimus after at least one ICI-containing regimen. Results:More > Graphic Abstract

    Effectiveness and Safety of Lenvatinib and Everolimus after Immune Checkpoint Inhibitors in Metastatic Renal Cell Cancer: A Systematic Review

  • Open Access

    ARTICLE

    Enhancing IoT-Enabled Electric Vehicle Efficiency: Smart Charging Station and Battery Management Solution

    Supriya Wadekar1,*, Shailendra Mittal1, Ganesh Wakte2, Rajshree Shinde2

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.071761 - 27 December 2025

    Abstract Rapid evolutions of the Internet of Electric Vehicles (IoEVs) are reshaping and modernizing transport systems, yet challenges remain in energy efficiency, better battery aging, and grid stability. Typical charging methods allow for EVs to be charged without thought being given to the condition of the battery or the grid demand, thus increasing energy costs and battery aging. This study proposes a smart charging station with an AI-powered Battery Management System (BMS), developed and simulated in MATLAB/Simulink, to increase optimality in energy flow, battery health, and impractical scheduling within the IoEV environment. The system operates through… More >

  • Open Access

    ARTICLE

    Influence of Sulfonated Chitosan on Conductivity of Sulfonated Polyether Ether Ketone (SPEEK) at Room Temperature

    Aina Aqilah Mohd Rizal1, Oskar Hasdinor Hassan2, Nor Kartini Jaafar1,2, Masnawi Mustaffa1, Mohd Tajudin Mohd Ali1,*, Ajis Lepit3, Nazli Ahmad Aini1,2,*

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.071726 - 27 December 2025

    Abstract Proton exchange membrane (PEM) is an integral component in fuel cells which enables proton transport for efficient energy conversion. Sulfonated Polyether Ether Ketone (SPEEK) has emerged as a cost-effective option with non-fluorinated aromatic backbones for Proton Exchange Membrane Fuel Cell (PEMFC) applications, even though it exhibits lower proton conductivity compared to Nafion. This work aims to study the influence of Sulfonated Chitosan (SCS) concentrations on proton conductivity of SPEEK-based PEM at room temperature. SPEEK was synthesized using a sulfonation process with concentrated sulfuric acid at room temperature. SCS was synthesized via reflux of CS and… More > Graphic Abstract

    Influence of Sulfonated Chitosan on Conductivity of Sulfonated Polyether Ether Ketone (SPEEK) at Room Temperature

  • Open Access

    ARTICLE

    Dynamic Boundary Optimization via IDBO-VMD: A Novel Power Allocation Strategy for Hybrid Energy Storage with Enhanced Grid Stability

    Zujun Ding, Qi Xiang, Chengyi Li, Mengyu Ma, Chutong Zhang, Xinfa Gu, Jiaming Shi, Hui Huang, Aoyun Xia, Wenjie Wang, Wan Chen, Ziluo Yu, Jie Ji*

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.070442 - 27 December 2025

    Abstract In order to address environmental pollution and resource depletion caused by traditional power generation, this paper proposes an adaptive iterative dynamic-balance optimization algorithm that integrates the Improved Dung Beetle Optimizer (IDBO) with Variational Mode Decomposition (VMD). The IDBO-VMD method is designed to enhance the accuracy and efficiency of wind-speed time-series decomposition and to effectively smooth photovoltaic power fluctuations. This study innovatively improves the traditional variational mode decomposition (VMD) algorithm, and significantly improves the accuracy and adaptive ability of signal decomposition by IDBO self-optimization of key parameters K and a. On this basis, Fourier transform technology… More >

  • Open Access

    REVIEW

    Curtain Wall Systems as Climate-Adaptive Energy Infrastructures: A Critical Review of Their Role in Sustainable Building Performance

    Samira Rastbod1, Mehdi Jahangiri2,*, Behrang Moradi1, Haleh Nazari1

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.070089 - 27 December 2025

    Abstract Curtain wall systems have evolved from aesthetic façade elements into multifunctional building envelopes that actively contribute to energy efficiency and climate responsiveness. This review presents a comprehensive examination of curtain walls from an energy-engineering perspective, highlighting their structural typologies (Stick and Unitized), material configurations, and integration with smart technologies such as electrochromic glazing, parametric design algorithms, and Building Management Systems (BMS). The study explores the thermal, acoustic, and solar performance of curtain walls across various climatic zones, supported by comparative analyses and iconic case studies including Apple Park, Burj Khalifa, and Milad Tower. Key challenges—including… More > Graphic Abstract

    Curtain Wall Systems as Climate-Adaptive Energy Infrastructures: A Critical Review of Their Role in Sustainable Building Performance

  • Open Access

    ARTICLE

    Coordinated Source–Network–Storage Inertia Control Strategy Based on Wind Power Transmission via MMC-HVDC System

    Mengxuan Shi1, Lintao Li2, Dejun Shao1, Xiaojie Pan1, Xingyu Shi2,*, Yuxun Wang2

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.069915 - 27 December 2025

    Abstract In wind power transmission via modular multilevel converter based high voltage direct current (MMC-HVDC) systems, under traditional control strategies, MMC-HVDC cannot provide inertia support to the receiving-end grid (REG) during disturbances. Moreover, due to the frequency decoupling between the two ends of the MMC-HVDC, the sending-end wind farm (SEWF) cannot obtain the frequency variation information of the REG to provide inertia response. Therefore, this paper proposes a novel coordinated source-network-storage inertia control strategy based on wind power transmission via MMC-HVDC system. First, the grid-side MMC station (GS-MMC) maps the frequency variations of the REG to… More >

  • Open Access

    ARTICLE

    Construction of MMC-CLCC Hybrid DC Transmission System and Its Power Flow Reversal Control Strategy

    Yechun Xin1, Xinyuan Zhao1, Dong Ding2, Shuyu Chen2, Chuanjie Wang2, Tuo Wang1,*

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.069748 - 27 December 2025

    Abstract To enhance power flow regulation in scenarios involving large-scale renewable energy transmission via high-voltage direct current (HVDC) links and multi-infeed DC systems in load-center regions, this paper proposes a hybrid modular multilevel converter–capacitor-commutated line-commutated converter (MMC-CLCC) HVDC transmission system and its corresponding control strategy. First, the system topology is constructed, and a submodule configuration method for the MMC—combining full-bridge submodules (FBSMs) and half-bridge submodules (HBSMs)—is proposed to enable direct power flow reversal. Second, a hierarchical control strategy is introduced, including MMC voltage control, CLCC current control, and a coordination mechanism, along with the derivation of… More >

  • Open Access

    ARTICLE

    Comprehensive Multi-Criteria Assessment of GBH-IES Microgrid with Hydrogen Storage

    Xue Zhang1, Jie Chen2,*, Zhihui Zhang3, Dewei Zhang3, Yuejiao Ming3, Xinde Zhang3

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.069487 - 27 December 2025

    Abstract The integration of wind power and natural gas for hydrogen production forms a Green and Blue Hydrogen Integrated Energy System (GBH-IES), which is a promising cogeneration approach characterized by multi-energy complementarity, flexible dispatch, and efficient utilization. This system can meet the demands for electricity, heat, and hydrogen while demonstrating significant performance in energy supply, energy conversion, economy, and environment (4E). To evaluate the GBH-IES system effectively, a comprehensive performance evaluation index system was constructed from the 4E dimensions. The fuzzy DEMATEL method was used to quantify the causal relationships between indicators, establishing a scientific input-output… More > Graphic Abstract

    Comprehensive Multi-Criteria Assessment of GBH-IES Microgrid with Hydrogen Storage

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