Steffen Schedler^1,*, Michael Bareev-Rudy¹, Stefanie Meilinger², Tanja Clees^1,3

Energy Engineering, Vol.122, No.5, pp. 1755-1770, 2025, DOI:10.32604/ee.2025.061962 - 25 April 2025

Abstract Germany aims to achieve a national climate-neutral energy system by 2045. The residential sector still accounts for 29% of end energy consumption, with 74% attributed to the direct use of fossil fuels for heating and hot water. In order to reduce fossil energy use in the household sector, great efforts are being made to design new energy concepts that expand the use of renewable energies to supply electricity and heat. One possibility is to convert parts of the natural gas grid to a hydrogen-based gas grid to deliver and store energy for urban quarters of… More >

Danijel Pavković^*, Pietro Kristović, Mihael Cipek, Dragutin Lisjak

Energy Engineering, Vol.122, No.5, pp. 1669-1696, 2025, DOI:10.32604/ee.2025.061916 - 25 April 2025

Abstract In deep drilling applications, such as those for geothermal energy, there are many challenges, such as those related to efficient operation of the drilling fluid (mud) pumping system. Legacy drilling rigs often use paired, parallel-connected independent-excitation direct-current (DC) motors for mud pumps, that are supplied by a single power converter. This configuration results in electrical power imbalance, thus reducing its efficiency. This paper investigates this power imbalance issue in such legacy DC mud pump drive systems and offers an innovative solution in the form of a closed-loop control system for electrical load balancing. The paper… More > Graphic Abstract

Daixuan Zhou¹, Zhichao Wang¹, Kaile Xi², Chong Zuo³, Yan Jia^2,*

Energy Engineering, Vol.122, No.5, pp. 2119-2153, 2025, DOI:10.32604/ee.2025.061712 - 25 April 2025

Abstract HOMER (Hybrid Optimization Model for Electric Renewables) is an effective simulation and optimization platform for hybrid renewable energy. By inputting specific users’ energy resource data (such as wind speed, solar radiation, etc.) and load data, and by determining the types and models of components selected by the user, HOMER calculates and simulates the operational status of each component at every time step. Ultimately, it computes the energy balance of the system within specified constraints to simulate the overall system operation. This approach enables the reasonable determination of system component capacities, the evaluation of system feasibility,… More > Graphic Abstract

MOEKA NAKASHIMA, NAOKO SUGA, AKARI FUKUMOTO, SAYURI YOSHIKAWA, SATORU MATSUDA^*

Oncology Research, Vol.33, No.5, pp. 1007-1017, 2025, DOI:10.32604/or.2025.059657 - 18 April 2025

Abstract Malignant tumors are heterogeneous diseases characterized by uncontrolled cell proliferation, invasion, metastasis, and/or recurrence of their malignancies. In particular, cancer stem cells (CSCs) within these tumors might be responsible for the property of invasiveness and/or therapies-resistance. CSCs are a self-renewing, awfully tumorigenic subpopulation of cancer cells, which are notorious for strong chemoresistance and are frequently responsible the aggravated invasion, metastasis, and/or recurrence. Developing targeting therapies against CSCs, therefore, may be deliberated a more encouraging mission for the greater cancer therapy. Innovation for a more potent anti-CSC treatment has been required as soon as possible.… More > Graphic Abstract

VERA RUZANOVA¹, ANASTASIA PROSKURINA¹, GENRIKH RITTER¹, EVGENIYA DOLGOVA¹, SOFYA OSHIKHMINA^1,2, SVETLANA KIRIKOVICH¹, EVGENIY LEVITES¹, YAROSLAV EFREMOV^2,3, OLEG TARANOV⁴, ALEXANDR OSTANIN⁵, ELENA CHERNYKH⁵, NIKOLAY KOLCHANOV⁶, SERGEY BOGACHEV^1,*

Oncology Research, Vol.33, No.5, pp. 1229-1248, 2025, DOI:10.32604/or.2025.059411 - 18 April 2025

Abstract Objectives: Currently, there exist two approaches to the treatment of malignant neoplasms: the Karanahan technology and in situ vaccination, which are based on chronometric delivery of therapeutic agents to the tumor depending on the characteristics of tumor cells, as well as the immune status. The main purpose of this study was to experimentally prove the feasibility of combining the Karanahan technology and in situ vaccination with αOX40 antibodies into a single therapeutic platform to achieve a potent additive antitumor therapeutic effect. Methods: BALB/c mice grafted with B-cellular lymphoma A20 were treated using the Karanahan technology consisting of… More >

Khaoula Ben Abdellafou¹, Kamel Zidi², Ahamed Aljuhani¹, Okba Taouali^1,*, Mohamed Faouzi Harkat³

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 3007-3023, 2025, DOI:10.32604/cmc.2025.063146 - 16 April 2025

Abstract Environmental protection requires identifying, investigating, and raising awareness about safeguarding nature from the harmful effects of both anthropogenic and natural events. This process of environmental protection is essential for maintaining human well-being. In this context, it is critical to monitor and safeguard the personal environment, which includes maintaining a healthy diet and ensuring plant safety. Living in a balanced environment and ensuring the safety of plants for green spaces and a healthy diet require controlling the nature and quality of the soil in our environment. To ensure soil quality, it is imperative to monitor and… More >

Khulud Salem Alshudukhi¹, Mamoona Humayun^2,*, Ghadah Naif Alwakid¹

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1973-1986, 2025, DOI:10.32604/cmc.2025.063077 - 16 April 2025

Abstract The Internet of Things (IoT) and edge computing have substantially contributed to the development and growth of smart cities. It handled time-constrained services and mobile devices to capture the observing environment for surveillance applications. These systems are composed of wireless cameras, digital devices, and tiny sensors to facilitate the operations of crucial healthcare services. Recently, many interactive applications have been proposed, including integrating intelligent systems to handle data processing and enable dynamic communication functionalities for crucial IoT services. Nonetheless, most solutions lack optimizing relaying methods and impose excessive overheads for maintaining devices’ connectivity. Alternatively, data More >

Xinyi Wang^*, Wanru Song, Chuanyan Hao, Feng Liu

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 3351-3368, 2025, DOI:10.32604/cmc.2025.062922 - 16 April 2025

Abstract As Deepfake technology continues to evolve, the distinction between real and fake content becomes increasingly blurred. Most existing Deepfake video detection methods rely on single-frame facial image features, which limits their ability to capture temporal differences between frames. Current methods also exhibit limited generalization capabilities, struggling to detect content generated by unknown forgery algorithms. Moreover, the diversity and complexity of forgery techniques introduced by Artificial Intelligence Generated Content (AIGC) present significant challenges for traditional detection frameworks, which must balance high detection accuracy with robust performance. To address these challenges, we propose a novel Deepfake detection… More >

Federica Uccello^1,2, Marek Pawlicki^3,4, Salvatore D'Antonio¹, Rafał Kozik^3,4, Michał Choraś^3,4,*

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1607-1621, 2025, DOI:10.32604/cmc.2025.062801 - 16 April 2025

Abstract The growing sophistication of cyberthreats, among others the Distributed Denial of Service attacks, has exposed limitations in traditional rule-based Security Information and Event Management systems. While machine learning–based intrusion detection systems can capture complex network behaviours, their “black-box” nature often limits trust and actionable insight for security operators. This study introduces a novel approach that integrates Explainable Artificial Intelligence—xAI—with the Random Forest classifier to derive human-interpretable rules, thereby enhancing the detection of Distributed Denial of Service (DDoS) attacks. The proposed framework combines traditional static rule formulation with advanced xAI techniques—SHapley Additive exPlanations and Scoped Rules More >

Shabana Ziyad Puthu Vedu^1,*, Wafaa A. Ghonaim², Naglaa M. Mostafa³, Pradeep Kumar Singh⁴

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2599-2617, 2025, DOI:10.32604/cmc.2025.062695 - 16 April 2025

Abstract Hearing and Speech impairment can be congenital or acquired. Hearing and speech-impaired students often hesitate to pursue higher education in reputable institutions due to their challenges. However, the development of automated assistive learning tools within the educational field has empowered disabled students to pursue higher education in any field of study. Assistive learning devices enable students to access institutional resources and facilities fully. The proposed assistive learning and communication tool allows hearing and speech-impaired students to interact productively with their teachers and classmates. This tool converts the audio signals into sign language videos for the… More >