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  • Open Access

    ARTICLE

    Optimal Design of High-Speed Partial Flow Pumps using Orthogonal Tests and Numerical Simulations

    Jiaqiong Wang1,2, Tao Yang1, Chen Hu1, Yu Zhang3,*, Ling Zhou1,2

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1203-1218, 2024, DOI:10.32604/fdmp.2023.045825

    Abstract To investigate the influence of structural parameters on the performances and internal flow characteristics of partial flow pumps at a low specific speed of 10000 rpm, special attention was paid to the first and second stage impeller guide vanes. Moreover, the impeller blade outlet width, impeller inlet diameter, blade inclination angle, and number of blades were considered for orthogonal tests. Accordingly, nine groups of design solutions were formed, and then used as a basis for the execution of numerical simulations (CFD) aimed at obtaining the efficiency values and heads for each design solution group. The More >

  • Open Access

    ARTICLE

    Structure Optimization of a Tesla Turbine Using an Organic Rankine Cycle Technology

    Yongguo Li1,2, Caiyin Xu1,2,*, Can Qin1,2, Dingjian Zheng1,2

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1251-1263, 2024, DOI:10.32604/fdmp.2023.044804

    Abstract The so-called ORC (Organic Rankine Cycle) heat recovery technology has attracted much attention with regard to medium and low temperature waste heat recovery. In the present study, it is applied to a Tesla turbine. At the same time, the effects of the disc speed, diameter and inter-disc gap on the internal flow field and output power of the turbine are also investigated by means of CFD (Computational Fluid Dynamics) numerical simulation, by which the pressure, velocity, and output efficiency of the internal flow field are obtained under different internal and external conditions. The highest efficiency More >

  • Open Access

    ARTICLE

    Investigation of the Damping Abilities of Sheep Wool Reinforced Expanded Polystyrene Core Layer Composites at Different Energies

    İbrahim Yavuz1,*, Ercan Şimşir1, Kenan Budak2

    Journal of Polymer Materials, Vol.41, No.1, pp. 1-14, 2024, DOI:10.32604/jpm.2024.052279

    Abstract In this study, natural fiber reinforced polymer foam core layered composites were produced for the automotive industry. Sheep wool was used as natural fiber. Polymer foam with a single layer XPS foam structure was used as the core material. XPS foams and fibers are bonded to the upper and lower sides of the foams with the help of resin. Samples were produced with one and two layers on both sides, with a total of two and four layers. Production was carried out using the vacuum bagging method using the manual laying method. After the production More >

  • Open Access

    ARTICLE

    LncRNA PCGEM1 facilitates cervical cancer progression via miR-642a-5p/KIF5B axis

    YUANLIN LIU1,3,#, YAN LIU2,#, YAN WANG2, QIANG WANG2, YAN YAN1, DANDAN ZHANG2,*, HUIQIN LIU2,*

    Oncology Research, Vol.32, No.7, pp. 1221-1229, 2024, DOI:10.32604/or.2024.047454

    Abstract At present, the role of many long non-coding RNAs (lncRNAs) as tumor suppressors in the formation and development of cervical cancer (CC) has been studied. However, lncRNA prostate cancer gene expression marker 1 (PCGEM1), whose high expression not only aggravates ovarian cancer but also can induce tumorigenesis and endometrial cancer progression, has not been studied in CC. The objective of this study was to investigate the expression and the underlying role of PCGEM1 in CC. The relative expression of PCGEM1 in CC cells was detected by real-time PCR. After the suppression of PCGEM1 expression by… More > Graphic Abstract

    LncRNA PCGEM1 facilitates cervical cancer progression via miR-642a-5p/KIF5B axis

  • Open Access

    ARTICLE

    ROR2 promotes invasion and chemoresistance of triple-negative breast cancer cells by activating PI3K/AKT/mTOR signaling

    XIA DA1, HAN GE2, JUNFENG SHI3, CHUNHUA ZHU1, GUOZHU WANG1, YUAN FANG4,*, JIN XU1,*

    Oncology Research, Vol.32, No.7, pp. 1209-1219, 2024, DOI:10.32604/or.2024.045433

    Abstract Objective: This study aimed to investigate the role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in triple-negative breast cancer (TNBC). Methods: ROR2 expression in primary TNBC and metastatic TNBC tissues was analyzed by immunohistochemical staining and PCR. ROR2 expression in TNBC cell lines was detected by PCR and Western blot analysis. The migration, invasion and chemosensitivity of TNBC cells with overexpression or knockdown of ROR2 were examined. Results: ROR2 expression was high in metastatic TNBC tissues. ROR2 knockdown suppressed the migration, invasion and chemoresistance of TNBC cells. ROR2 overexpression in MDA-MB-435 cells promoted the migration, More >

  • Open Access

    ARTICLE

    IKIP downregulates THBS1/FAK signaling to suppress migration and invasion by glioblastoma cells

    ZHAOYING ZHU1,#, YANJIA HU2,#, FENG YE2, HAIBO TENG2, GUOLIANG YOU1, YUNHUI ZENG2, MENG TIAN2, JIANGUO XU2, JIN LI2, ZHIYONG LIU2, HAO LIU2,*, NIANDONG ZHENG1,*

    Oncology Research, Vol.32, No.7, pp. 1173-1184, 2024, DOI:10.32604/or.2024.042456

    Abstract Background: Inhibitor of NF-κB kinase-interacting protein (IKIP) is known to promote proliferation of glioblastoma (GBM) cells, but how it affects migration and invasion by those cells is unclear. Methods: We compared levels of IKIP between glioma tissues and normal brain tissue in clinical samples and public databases. We examined the effects of IKIP overexpression and knockdown on the migration and invasion of GBM using transwell and wound healing assays, and we compared the transcriptomes under these different conditions to identify the molecular mechanisms involved. Results: Based on data from our clinical samples and from public databases, More >

  • Open Access

    ARTICLE

    Identification of Secondary Metabolites in Tunisian Tilia platyphyllos Scop. Using MALDI-TOF and GC-MS

    Ayda Khadhri1, Mohamed Mendili1, Marwa Bannour-Scharinger1, Eric Masson2, Antonio Pizzi2,*

    Journal of Renewable Materials, Vol.12, No.4, pp. 827-842, 2024, DOI:10.32604/jrm.2024.046950

    Abstract This study is the first to evaluate the phytochemical content and biological properties of Tunisian T. platyphyllos Scop. A total of 23 compounds of essential oils were identified by gas chromatography-mass spectrometry (GC-MS) analysis of bracts and fruit extracts. The results show that oxygenated monoterpenes were the dominant class of essential oils. The phenolic composition was investigated by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). The analysis showed that the chemical profiles of the ethanolic extracts of bracts and fruits are substantially similar. The highest polyphenol content was found in the ethanolic extracts of the fruits (7.65… More > Graphic Abstract

    Identification of Secondary Metabolites in Tunisian <i>Tilia platyphyllos</i> Scop. Using MALDI-TOF and GC-MS

  • Open Access

    ARTICLE

    Morphological Evolution of Self-Assembled Sodium Dodecyl Sulfate/Dodecyltrimethylammonium Bromide@Epoxy-β-Cyclodextrin Supramolecular Aggregates Induced by Temperature

    Qingran Meng1,2, Wenwen Xu2, Zuobing Xiao2, Qinfei Ke1,2,*, Xingran Kou1,2,*

    Journal of Renewable Materials, Vol.12, No.4, pp. 629-641, 2024, DOI:10.32604/jrm.2023.029182

    Abstract Bio-based cyclodextrins (CDs) are a common research object in supramolecular chemistry. The special cavity structure of CDs can form supramolecular self-assemblies such as vesicles and microcrystals through weak interaction with guest molecules. The different forms of supramolecular self-assemblies can be transformed into each other under certain conditions. The regulation of supramolecular self-assembly is not only helpful to understand the self-assembly principle, but also beneficial to its application. In the present study, the self-assembly behavior of epoxy-β-cyclodextrin (EP-β-CD) and mixed anionic and cationic surfactant system (sodium dodecyl sulfate/dodecyltrimethylammonium bromide, SDS/DTAB) in aqueous solution was studied. Morphological… More > Graphic Abstract

    Morphological Evolution of Self-Assembled Sodium Dodecyl Sulfate/Dodecyltrimethylammonium Bromide@Epoxy-β-Cyclodextrin Supramolecular Aggregates Induced by Temperature

  • Open Access

    ARTICLE

    Reinforcement Effect of Recycled CFRP on Cement-Based Composites: With a Comparison to Commercial Carbon Fiber Powder

    Hantao Huang, Zhifang Zhang*, Zhenhua Wu, Yao Liu

    Structural Durability & Health Monitoring, Vol.18, No.4, pp. 409-423, 2024, DOI:10.32604/sdhm.2024.048597

    Abstract In this paper, recycled carbon fiber reinforced polymer (CFRP) mixture (CFRP-M, including recycled carbon fiber and powder) and refined recycled CFRP fiber (CFRP-F, mostly recycled carbon fiber) were added to cement to study the influence of addition on the flexural strength, compressive strength, and fluidity of cement-based materials. The recycled CFRP were prepared by mechanically processing the prepreg scraps generated during the manufacture of CFRP products. For comparison, commercial carbon fiber powder was also added in cement and the performance was compared to that of addition of recycled CFRP. The hydration products and strengthening mechanism… More >

  • Open Access

    ARTICLE

    Circular RNA circ_0003609 ameliorates hypertrophied ligamentum flavum by regulating the miR-155/SIRT1 axis

    GUIBIN ZHONG1,2,#, SHURONG WANG3,#, YUJIN HE4, DAMING FENG1, KE WEI1, YANQIU YANG1, JIANWEI CHEN1,2,*, JUNLING CHEN1,*

    BIOCELL, Vol.48, No.6, pp. 1001-1008, 2024, DOI:10.32604/biocell.2024.050294

    Abstract Background: Hypertrophy of the ligamentum flavum (HLF) is a common contributor to spinal stenosis which results in significant neurological impairments. Circular RNA (circRNA) circ_0003609 has been linked to HLF; however, the exact mechanism by which it causes this disease is unclear. Methods: Circ_0003609 expressions were regulated in HLF cells by overexpression vectors and RNA interference. Cell proliferation and fibrosis-related gene expression were checked by the Cell Counting Kit-8 (CCK-8) assay and western blotting. CircBank’s prediction of the association between miR-155 and circ_0003609 was supported by a dual-luciferase reporter experiment. The function of the miR-155/sirtuin 1 More >

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