Chengkan Xu^1,2,4, Xiaofei Wang³, Yixuan Li², Guannan Wang^2,*, He Zhang^2,4,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 957-974, 2024, DOI:10.32604/cmes.2024.047327

Abstract Structural damage in heterogeneous materials typically originates from microstructures where stress concentration occurs. Therefore, evaluating the magnitude and location of localized stress distributions within microstructures under external loading is crucial. Repeating unit cells (RUCs) are commonly used to represent microstructural details and homogenize the effective response of composites. This work develops a machine learning-based micromechanics tool to accurately predict the stress distributions of extracted RUCs. The locally exact homogenization theory efficiently generates the microstructural stresses of RUCs with a wide range of parameters, including volume fraction, fiber/matrix property ratio, fiber shapes, and loading direction. Subsequently, the conditional generative adversarial network… More > Graphic Abstract

Yanmei Shi¹, Wei Yu^2,*, Yanxia Zhao^3,*, Yungang Jia⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 887-906, 2024, DOI:10.32604/cmes.2024.046140

Abstract Web application fingerprint recognition is an effective security technology designed to identify and classify web applications, thereby enhancing the detection of potential threats and attacks. Traditional fingerprint recognition methods, which rely on preannotated feature matching, face inherent limitations due to the ever-evolving nature and diverse landscape of web applications. In response to these challenges, this work proposes an innovative web application fingerprint recognition method founded on clustering techniques. The method involves extensive data collection from the Tranco List, employing adjusted feature selection built upon Wappalyzer and noise reduction through truncated SVD dimensionality reduction. The core of the methodology lies in… More >

YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB^*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

LIJUAN ZHANG^1,#, QINGYIN MENG^2,#, LI ZHUANG¹, QUAN GONG¹, XIANDA HUANG³, XUEQIN LI¹, SHIJUAN LI¹, GUOQIN WANG⁴, XICAI WANG^5,*

BIOCELL, Vol.48, No.4, pp. 581-590, 2024, DOI:10.32604/biocell.2024.047260

Abstract Background: Lung adenocarcinoma is a very pervasive histological form of lung cancers, and inhibiting metastasis is crucial for effective treatment. In this investigation, we explored the functional interaction of miR-30a-5p and the putative transcription factor 2 of the homeodomain (PHTF2) in dictating the aggressiveness and metastasis of lung adenocarcinoma. Method: We collected clinical samples to evaluate the expression patterns of miR-30a-5p and PHTF2 in lung adenocarcinoma along with normal tissues. Cellular experiments including cell count kit (CCK)-8 growth assay, apoptosis analysis, migration and invasion examinations were performed to assess the aggressiveness of lung adenocarcinoma cells. Furthermore, we examined tumorigenesis and… More > Graphic Abstract

DANPING ZHU^1,#, GUANGMING LIU^1,#, KUAN FENG¹, SUYUN LI¹, DANDAN HU², SIDA YANG^3,*, PEIQING LI^1,*

BIOCELL, Vol.48, No.4, pp. 653-664, 2024, DOI:10.32604/biocell.2024.044856

Abstract Background: During Enterovirus type 71 (EV71) infection, the structural viral protein 1 (VP1) activates endoplasmic reticulum (ER) stress associated with peripheral myelin protein 22 (PMP22) accumulation and induces autophagy. However, the specific mechanism behind this process remains elusive. Methods: In this research, we used the VP1-overexpressing mouse Schwann cells (SCs) models co-transfected with a PMP22 silencing or Autocrine motility factor receptor (AMFR/gp78) overexpressing vector to explore the regulation of gp78 on PMP22 and its relationship with autophagy and apoptosis. Results: The activity of gp78 could be influenced by EV71-VP1, leading to a decrease in the ubiquitination and degradation of PMP22,… More >

JHILAM PRAMANIK^1,#, AKASH KUMAR², SARVESH RUSTAGI^3,#, MEHAK KATYAL⁴, SHEETAL THAKUR⁵, JUTISHNA BORA⁶, SUMIRA MALIK^6,7,*, ANCHAL TREHAN⁸, NAYAN TALUKDAR⁹, PETR SLAMA^10,*

BIOCELL, Vol.48, No.4, pp. 541-557, 2024, DOI:10.32604/biocell.2023.029031

Abstract Many phytochemicals and their derived metabolites produced by plants are extensively employed in commercial goods, pharmaceutical products as well as in the environmental and medical fields. However, these secondary metabolites obtained from plants are in low amounts, and it is difficult to synthesize them at the industrial level. Despite these challenges, they may be utilized for a variety of medicinal products that are either available in the market or are being researched and tested. Secondary metabolites are complex compounds that exhibit chirality. Further, under controlled conditions with elicitors, desired secondary metabolites may be produced from plant cell cultures. This review… More > Graphic Abstract

Joseph O. Dirisu^1,*, Imhade P. Okokpujie^2,3,*, Olufunmilayo O. Joseph¹, Sunday O. Oyedepo¹, Oluwasegun Falodun⁴, Lagouge K. Tartibu³, Firdaussi D. Shehu¹

Journal of Renewable Materials, Vol.12, No.3, pp. 485-511, 2024, DOI:10.32604/jrm.2024.045188

Abstract Research into converting waste into viable eco-friendly products has gained global concern. Using natural fibres and pulverized metallic waste becomes necessary to reduce noxious environmental emissions due to indiscriminately occupying the land. This study reviews the literature in the broad area of green composites in search of materials that can be used in automotive brake pads. Materials made by biocomposite, rather than fossil fuels, will be favoured. A database containing the tribo-mechanical performance of numerous potential components for the future green composite was established using the technical details of bio-polymers and natural reinforcements. The development of materials with diverse compositions… More > Graphic Abstract

R. VENKATESAN^*, S. R. DARSON IMMANUEL JOHN, N. RAJESWARI

Journal of Polymer Materials, Vol.36, No.3, pp. 261-273, 2019, DOI:10.32381/JPM.2019.36.03.6

Abstract Nanocomposite films of chitosan (CH) incorporated with different wt. % of the polyoligomericsilsesquioxane (POSS) were prepared by solution casting. The thermal, mechanical, morphological and antimicrobial properties of the nanocomposites were examined. TGA analyses of the nanocomposites indicate that the filler enables the enhancement of thermal stability of chitosan. The tensile strength of the nanocomposite films is enhanced (10.9 MPa for neat chitosan to 24.0MPa for 5wt. % filled chitosan) by the addition of POSS while the elongation at break is reduced. The nanocomposite films exhibited excellent antimicrobial activity against both gram positive and gram negative bacteria. This activity increases with… More >

RUBY AHMED¹, MOHAMMAD OMAISH ANSARI², FARMAN ALI¹, SHAHID PERVEZ ANSARI^1,*

Journal of Polymer Materials, Vol.36, No.3, pp. 243-251, 2019, DOI:10.32381/JPM.2019.36.03.4

Abstract Polyaniline (PANI) and molybdenum disulphide (MoS₂ ) were used to prepare nanocomposites by in-situ oxidative polymerization of acidified aniline in presence of dispersed MoS₂ in the reaction mixture. Electron Microscopy (SEM & TEM), Fourier Transform Infrared (FTIR) spectroscopy, Ultraviolet-Visible (UV-Vis) spectroscopy, and X-ray diffraction (XRD) were used to characterize these nanocomposites. SEM micrographs showed that PANI is present on the layers of MoS₂ which were exfoliated during the preparation and the presence of MoS₂ is also confirmed by XRD peaks. The nanocomposites were studied for their electrical conductivity and stability of electrical conductivity in terms of d.c. electrical conductivity retention.… More >

KAVITA^*, R.K. TIWARI

Journal of Polymer Materials, Vol.36, No.2, pp. 195-205, 2019, DOI:10.32381/JPM.2019.36.02.7

Abstract The effect of poly (vinyl butyral) and acid functionalized multiwalled carbon nanotubes (f-MWCNT) on the thermal and mechanical performance of Kevlar fiber reinforced novolac epoxy nanocomposites was investigated and presented in this paper. Nanocomposite containing 1.5 wt. % poly (vinyl butyral) and 0.5 wt. % f-MWCNT exhibited best thermal and mechanical properties (except flexural strength) among all the nanocomposites reported here. It showed ~5%, 27% and 126 % improvement in tensile strength, young’s modulus and impact strength respectively as compared to the neat novolac epoxy Kevlar composite.Nanocomposite containing 0.5 wt. % f- MWCNT and 2 wt. % poly (vinyl butyral)… More >