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  • Open Access

    ARTICLE

    Identification of Secondary Metabolites in Tunisian Tilia platyphyllos Scop. Using MALDI-TOF and GC-MS

    Ayda Khadhri1, Mohamed Mendili1, Marwa Bannour-Scharinger1, Eric Masson2, Antonio Pizzi2,*

    Journal of Renewable Materials, Vol.12, No.4, pp. 827-842, 2024, DOI:10.32604/jrm.2024.046950

    Abstract This study is the first to evaluate the phytochemical content and biological properties of Tunisian T. platyphyllos Scop. A total of 23 compounds of essential oils were identified by gas chromatography-mass spectrometry (GC-MS) analysis of bracts and fruit extracts. The results show that oxygenated monoterpenes were the dominant class of essential oils. The phenolic composition was investigated by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). The analysis showed that the chemical profiles of the ethanolic extracts of bracts and fruits are substantially similar. The highest polyphenol content was found in the ethanolic extracts of the fruits (7.65… More > Graphic Abstract

    Identification of Secondary Metabolites in Tunisian <i>Tilia platyphyllos</i> Scop. Using MALDI-TOF and GC-MS

  • Open Access

    ARTICLE

    Morphological Evolution of Self-Assembled Sodium Dodecyl Sulfate/Dodecyltrimethylammonium Bromide@Epoxy-β-Cyclodextrin Supramolecular Aggregates Induced by Temperature

    Qingran Meng1,2, Wenwen Xu2, Zuobing Xiao2, Qinfei Ke1,2,*, Xingran Kou1,2,*

    Journal of Renewable Materials, Vol.12, No.4, pp. 629-641, 2024, DOI:10.32604/jrm.2023.029182

    Abstract Bio-based cyclodextrins (CDs) are a common research object in supramolecular chemistry. The special cavity structure of CDs can form supramolecular self-assemblies such as vesicles and microcrystals through weak interaction with guest molecules. The different forms of supramolecular self-assemblies can be transformed into each other under certain conditions. The regulation of supramolecular self-assembly is not only helpful to understand the self-assembly principle, but also beneficial to its application. In the present study, the self-assembly behavior of epoxy-β-cyclodextrin (EP-β-CD) and mixed anionic and cationic surfactant system (sodium dodecyl sulfate/dodecyltrimethylammonium bromide, SDS/DTAB) in aqueous solution was studied. Morphological… More > Graphic Abstract

    Morphological Evolution of Self-Assembled Sodium Dodecyl Sulfate/Dodecyltrimethylammonium Bromide@Epoxy-β-Cyclodextrin Supramolecular Aggregates Induced by Temperature

  • Open Access

    ARTICLE

    Reinforcement Effect of Recycled CFRP on Cement-Based Composites: With a Comparison to Commercial Carbon Fiber Powder

    Hantao Huang, Zhifang Zhang*, Zhenhua Wu, Yao Liu

    Structural Durability & Health Monitoring, Vol.18, No.4, pp. 409-423, 2024, DOI:10.32604/sdhm.2024.048597

    Abstract In this paper, recycled carbon fiber reinforced polymer (CFRP) mixture (CFRP-M, including recycled carbon fiber and powder) and refined recycled CFRP fiber (CFRP-F, mostly recycled carbon fiber) were added to cement to study the influence of addition on the flexural strength, compressive strength, and fluidity of cement-based materials. The recycled CFRP were prepared by mechanically processing the prepreg scraps generated during the manufacture of CFRP products. For comparison, commercial carbon fiber powder was also added in cement and the performance was compared to that of addition of recycled CFRP. The hydration products and strengthening mechanism… More >

  • Open Access

    ARTICLE

    Circular RNA circ_0003609 ameliorates hypertrophied ligamentum flavum by regulating the miR-155/SIRT1 axis

    GUIBIN ZHONG1,2,#, SHURONG WANG3,#, YUJIN HE4, DAMING FENG1, KE WEI1, YANQIU YANG1, JIANWEI CHEN1,2,*, JUNLING CHEN1,*

    BIOCELL, Vol.48, No.6, pp. 1001-1008, 2024, DOI:10.32604/biocell.2024.050294

    Abstract Background: Hypertrophy of the ligamentum flavum (HLF) is a common contributor to spinal stenosis which results in significant neurological impairments. Circular RNA (circRNA) circ_0003609 has been linked to HLF; however, the exact mechanism by which it causes this disease is unclear. Methods: Circ_0003609 expressions were regulated in HLF cells by overexpression vectors and RNA interference. Cell proliferation and fibrosis-related gene expression were checked by the Cell Counting Kit-8 (CCK-8) assay and western blotting. CircBank’s prediction of the association between miR-155 and circ_0003609 was supported by a dual-luciferase reporter experiment. The function of the miR-155/sirtuin 1 More >

  • Open Access

    ARTICLE

    OPA3 overexpression modulates lipid droplet production and sensitizes colorectal cancer cells to bevacizumab treatment

    HONGBIAO WU*, DONGFANG LIU

    BIOCELL, Vol.48, No.6, pp. 971-980, 2024, DOI:10.32604/biocell.2024.049466

    Abstract Background: Colorectal cancer (CRC) represents a substantial risk to public health. Bevacizumab, the first US FDA-approved antiangiogenic drug (AAD) for human CRC treatment, faces resistance in patients. The role of lipid metabolism, particularly through OPA3-regulated lipid droplet production, in overcoming this resistance is under investigation. Methods: The protein expression pattern of OPA3 in CRC primary/normal tissues was evaluated by bioinformatics analysis. OPA3-overexpressed SW-480 and HCT-116 cell lines were established, and bevacizumab resistance and OPA3 effects on cell malignancy were examined. OPA3 protein/mRNA expression and lipid droplet-related genes were measured with Western blot and qRT-PCR. OPA3… More > Graphic Abstract

    OPA3 overexpression modulates lipid droplet production and sensitizes colorectal cancer cells to bevacizumab treatment

  • Open Access

    ARTICLE

    UBE2T mediates the stemness properties of breast cancer cells through the mTOR signaling pathway

    JIAWEI YIN1, YONGSHENG WANG2,3, GUANGWEI WEI4, MINGXIN WEN3,*

    BIOCELL, Vol.48, No.6, pp. 959-970, 2024, DOI:10.32604/biocell.2024.049349

    Abstract Objectives: This study aimed to reveal the role and possible mechanism of the ubiquitin-conjugating enzyme 2T (UBE2T) in the biological activities of breast cancer stem cells (BCSCs). Methods: The specific protein and gene expression were quantified by Western blotting and quantitative real-time polymerase chain reaction, the proportion of BCSCs was examined by flow cytometry, and the self-renewal and proliferation of BCSCs were verified by serial sphere formation and soft agar. Results: Increasing expression of UBE2T was drastically found in breast cancer than that in adjacent tissues. Furthermore, UBE2T overexpression significantly increased the proportion of BCSCs in More >

  • Open Access

    RETRACTION

    Retraction: KIF18A is a potential prognostic factor and promotes tumor progression in oral tongue squamous cell carcinoma

    BIOCELL Editorial Office

    BIOCELL, Vol.48, No.6, pp. 1009-1009, 2024, DOI:10.32604/biocell.2024.054510

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Investigation of Cavitation in NaCl Solutions in a Sonochemical Reactor Using the Foil Test Method

    Michael Kuchinskiy1,2,*, Tatyana Lyubimova1,2, Konstantin Rybkin2, Anastasiia Sadovnikova2, Vasiliy Galishevskiy2

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 1093-1102, 2024, DOI:10.32604/fdmp.2024.050059

    Abstract Ultrasonic baths and sonochemical reactors are widely used in industrial applications dealing with surface cleaning and chemical synthesis. The processes of erosion, cleaning and structuring of the surface can be typically controlled by changing relevant influential parameters. In particular, in this work, we experimentally investigate the effect of NaCl concentration (0–5.5 mol/L) on the erosion of an aluminum foil under ultrasonic exposure at a frequency of 28 kHz. Special attention is paid to the determination of cavitation zones and their visualization using heat maps. It is found that at low NaCl concentration (0.3 mol/L), the More > Graphic Abstract

    Investigation of Cavitation in NaCl Solutions in a Sonochemical Reactor Using the Foil Test Method

  • Open Access

    ARTICLE

    Analysis of Calcined Red Mud Properties and Related Mortar Performances

    Zhengfan Lyu1,3, Yulin Li2,3, Mengmeng Fan1,3,*, Yan Huang1, Chenguang Li2

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 901-913, 2024, DOI:10.32604/fdmp.2023.043512

    Abstract Red mud (RM) is a low-activity industrial solid waste, and its utilization as a resource is currently a hot topic. In this study, the micro characteristics of red mud at different calcination temperatures were analyzed using X-ray diffraction and scanning electron microscopy. The performance of calcined red mud was determined through mortar strength tests. Results indicate that high-temperature calcination can change the mineral composition and microstructure of red mud, and increase the surface roughness and specific surface area. At the optimal temperature of 700°C, the addition of calcined red mud still leads to a decrease More > Graphic Abstract

    Analysis of Calcined Red Mud Properties and Related Mortar Performances

  • Open Access

    ARTICLE

    CSTB Downregulation Promotes Cell Proliferation and Migration and Suppresses Apoptosis in Gastric Cancer SGC-7901 Cell Line

    Jian Zhang*1, ZhenFeng Shi†1, JinXing Huang, XiaoGuang Zou§

    Oncology Research, Vol.24, No.6, pp. 487-494, 2016, DOI:10.3727/096504016X14685034103752

    Abstract This study aimed to investigate the pivotal role of cystatin B (CSTB) in the development of gastric cancer and to explore its possible regulatory mechanism. Human gastric cancer SGC-7901 cells as a model in vitro were transfected with plasmid PCDNA3.1-CSTB and siRNA-CSTB using Lipofectamine 2000. Quantitative realtime PCR (qRT-PCR) and Western blotting were performed to determine the relative expression of CSTB and PI3K/Akt/mTOR pathway-related protein. Moreover, MTT assay, Transwell assay, and flow cytometry were used to assess cell proliferation, migration, and apoptosis, respectively. The results showed that CSTB was significantly downregulated in SGC-7901 cells compared… More >

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