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  • Open Access

    ARTICLE

    IConFuzz: Constraint-Aware Argument Mutation for Effective Smart Contract Fuzzing

    Hojin Choi, Jaeseung Choi*

    CMC-Computers, Materials & Continua, Vol.88, No.3, 2026, DOI:10.32604/cmc.2026.082577 - 23 July 2026

    Abstract Recently, extensive research has focused on addressing the unique challenges of smart contract fuzzing. Nevertheless, existing fuzzers still struggle to generate adequate function call arguments that can explore the deep smart contract states. In this paper, we introduce novel classes of argument constraints that capture the inter-argument relationships required to exercise meaningful contract logic. We propose a static analysis algorithm to extract these constraints from Solidity source code. In addition, we design a constraint-aware argument mutation strategy that leverages the identified constraints to guide test case generation for smart contract fuzzing. We implement our approach More >

  • Open Access

    ARTICLE

    Security Audit of Tuya Smart Lock Using Penetration Testing Methodology

    Saken Tleuberdin1, Dina Satybaldina2,*, Raikhan Muratkhan3, Gulsipat Abisheva2,*

    CMC-Computers, Materials & Continua, Vol.88, No.3, 2026, DOI:10.32604/cmc.2026.081906 - 23 July 2026

    Abstract We perform a cross-layer penetration testing on one of the most popular Wi-Fi smart locks (Tuya 902V). The methodology combines wireless traffic analysis using an Alfa AWUS036AXML adapter, forced re-association via deauthentication to make Wi-Fi Protected Access 2 (WPA2) 4-way Extensible Authentication Protocol over LAN (EAPOL) handshake visible with Airodump/Aireplay, offline dictionary attack with Aircrack-ng, Android app reverse engineering using Apktool, Jadx, and MobSF; denial-of-service experiment (DoS) executed by hping3; Near-Field Communications (NFC)/Radio-Frequency Identification (RFID) key-clone attempt by Flipper Zero. Handshake is empirically captured but no Wi-Fi passphrase found under 14M dictionary entries; DoS test… More >

  • Open Access

    ARTICLE

    Knowledge–Rule–Decision: A Loosely-Coupled Architecture for Auditable High-Stakes Clinical Decision Support

    Bailing Zhang*, Genlang Chen

    Journal of Intelligent Medicine and Healthcare, Vol.4, pp. 109-124, 2026, DOI:10.32604/jimh.2026.084876 - 21 July 2026

    Abstract High-stakes clinical decision support (CDS) demands a property that aggregate accuracy cannot capture: a trace that a clinician who was not in the room can inspect layer by layer when the system is wrong. We argue that the way to obtain this property is to refuse to entangle the large language model (LLM) with the rest of the pipeline. We propose KRD (Knowledge–Rule–Decision), a four-component architecture that separates fact extraction, a compile-time clinical knowledge layer in the spirit of the LLM Wiki pattern of Karpathy, a rule layer of hand-written contraindications and heuristics, and a decision… More >

  • Open Access

    ARTICLE

    Breast Cancer Cell-Derived Exosomal miR-92b-3p Promotes Tumor Angiogenesis and Metastasis by Suppressing PTEN in Vascular Endothelial Cells

    Tingting Yang1, Meng Guan1, Xin Guan1, Lihua Kang1, Xiaomeng Wang1, Yanjie Guan1, Yang Yang2, Wei Deng3, Guoxiang Wang1,*

    Oncology Research, Vol.34, No.8, 2026, DOI:10.32604/or.2026.083563 - 16 July 2026

    Abstract Background: Tumor-driven vascular remodeling is crucial for breast cancer metastasis; yet, the role of tumor-derived exosomal miRNAs in this process remains underexplored. This study aimed to investigate the clinical relevance and the underlying mechanism of breast cancer-derived exosomal miR-92b-3p in endothelial reprogramming. Methods: miR-92b-3p expression was evaluated in the TCGA cohort and clinical patient samples. The effects of exosomal miR-92b-3p from breast cancer cells on recipient human microvascular endothelial cells (HMVECs) were assessed using in vitro angiogenesis, migration, and permeability assays, alongside in vivo murine xenograft models. Mechanistic targets were validated via dual-luciferase and rescue experiments. Results: miR-92b-3p was… More >

  • Open Access

    ARTICLE

    The Construction and Preclinical Evaluation of Antitumor Activity of a Novel MIgG-OXA ADC in Lung Adenocarcinoma

    Haijun Sun1,#, Wenyue Yan2,#, Zhanyu Li3,#, Qintian Li4, Qilong Du4, Li Xu5, Wanwei Cao3, Junrong Yang6, Xilan Yang2, Jun Chen7,*, Yuan Mao8,*, Wen Huang4,*

    Oncology Research, Vol.34, No.8, 2026, DOI:10.32604/or.2026.080413 - 16 July 2026

    Abstract Background: The melanoma-associated antigen-A1 (MAGE-A1) demonstrates tumor-restricted expression patterns in diverse malignancies, positioning it as an attractive therapeutic target. This investigation aimed to engineer and validate a novel antibody-drug conjugate with oxaliplatin targeting MAGE-Al (MIg-OXA), a novel antibody-drug conjugate targeting MAGE-A1, while assessing its therapeutic potential against MAGE-A1-expressing lung adenocarcinoma through both cellular and animal models. Methods: We generated a MAGE-A1-specific immunoglobulin G (IgG) antibody (MIgG) and subsequently conjugated it with oxaliplatin (OXA) to produce MIgG-OXA. The conjugate’s binding specificity and cellular uptake were verified through cell-based enzyme-linked immunosorbent assay (ELISA), flow cytometric analysis, and immunofluorescence… More >

  • Open Access

    ARTICLE

    Mapping Characteristics of the Filtration Performance of Gas Turbine Inlet Air Filters under Typical Environmental Conditions

    Yan Shi1,2,*, Rong Zhuang2, Yunshan Bai2, Wenguo Xiang1, Cai Liang1

    Energy Engineering, Vol.123, No.8, 2026, DOI:10.32604/ee.2026.082971 - 12 July 2026

    Abstract The performance evaluation of gas turbine inlet air filtration systems is commonly based on standardized laboratory testing; however, discrepancies frequently arise between laboratory results and actual operating performance. In this study, an on-site testing apparatus was developed to investigate filtration behavior under realistic operating conditions. Field measurements were conducted to analyze pressure loss evolution, particle-size-dependent filtration efficiency, and the influence of environmental parameters, including temperature, humidity, and ambient particulate concentration. Results show that filter pressure loss increased progressively with operational loading, while short-term fluctuations were associated with variations in environmental conditions. Filtration efficiency exhibited an… More >

  • Open Access

    ARTICLE

    A New Well-Testing Method for Pumping-Shutdown Data of Multi-Fractured Horizontal Wells: A Case Study from the Sichuan Shale Gas Basin

    Xuefeng Yang1,2, Chunyu Ren1,2, Deliang Zhang1,2, Huaicai Fan1,2, Yue Chen1,2, Yue Yang1,2, Yan Zhang1,2, Shuai Wu1,2, Baoyun Zhang3,*, Xin Zhao3

    Energy Engineering, Vol.123, No.8, 2026, DOI:10.32604/ee.2025.074956 - 12 July 2026

    Abstract In southern Sichuan’s deep shale gas development, multi-stage fractured horizontal wells are commonly used. Evaluating fracturing results is challenging due to complex fracture networks. This study classifies fracture systems into four types: single-wing, bi-wing, branched, and serial fractures. A discrete fracture model (DFM) combined with matrix-fracture flow is used to establish a single-stage well testing interpretation model. To address multi-solution issues in well testing, an equivalent fracture network model based on a trilinear flow model is proposed, adjusting crossflow coefficients and the fracture network volume ratio. The study finds significant differences in the pressure derivative More >

  • Open Access

    ARTICLE

    Low-Velocity Impact Properties of Quad and Double-Double Composite Laminates

    Muhammad Mudassar1, Lei Cai1, Qi Zhang2, Deng’an Cai1,*

    Journal of Polymer Materials, Vol.43, No.2, 2026, DOI:10.32604/jpm.2026.080344 - 30 June 2026

    Abstract In this work, a comprehensive numerical study of the low-velocity impact (LVI) behavior of QUAD laminates vs. Double-Double (DD) stacking sequences has been performed. Finite element models were drawn, and analyses carried out in Abaqus/Explicit employing continuum shell elements (SC8R) for the plies, cohesive elements (COH3D8) for the delamination interfaces, and the built-in Hashin damage criterion for intralaminar failure. Two different impact energies (50 and 100 J) were applied using a hemispherical impactor mass of 6.25 kg, and the impact histories were investigated in force-time, displacement-time, and energy-absorption responses. The QUAD layup provided the stiffest… More >

  • Open Access

    ARTICLE

    Structural Amorphization and Ionic Transport Behavior of Phytagel–NaClO4 Biopolymer Electrolytes

    Norlela Manja Ahmad1, Farisha Irdina Muhammad Ridzuan1, Nur Farisha Sulthan Hussain1, Siti Zafirah Zainal Abidin1,2,*

    Journal of Polymer Materials, Vol.43, No.2, 2026, DOI:10.32604/jpm.2026.078419 - 30 June 2026

    Abstract Materials sustainability is becoming increasingly important across advanced technologies, driving the development of environmentally friendly electrolyte systems. In this work, biopolymer electrolytes were prepared using Phytagel as the host polymer and varying concentrations of sodium perchlorate (NaClO4) as the dopant salt via the solution-casting method for sodium-ion battery applications. The prepared biopolymer electrolytes were characterised using various techniques to assess changes in their morphology and electrical performance. X-ray diffraction (XRD) confirms the crystalline/amorphous nature of the prepared biopolymer electrolytes, and the membrane with 40 wt.% NaClO4 exhibits a high degree of amorphousness. Peak-deconvoluted XRD analysis confirms… More >

  • Open Access

    ARTICLE

    Partial Oxidation of Diacrylates to Produce Epoxy-Acrylate Hybrid Monomers: Precursors for Ambient-Curable Polymeric Epoxy Resins

    Bungo Ochiai*, Yuji Kamachi, Yoshimasa Matsumura#

    Journal of Polymer Materials, Vol.43, No.2, 2026, DOI:10.32604/jpm.2026.078288 - 30 June 2026

    Abstract Epoxy-acrylate hybrid systems are extensively employed in adhesives, coatings, and composites; however, conventional formulations often rely on toxic monomers such as glycidyl methacrylate (GMA). This study introduces a sequentially curable epoxy-acrylate hybrid system based on novel hybrid monomers containing both glycidate and acrylate groups, synthesized via the partial oxidation of a diacrylate. Radical polymerization of monomers with a glycidate content exceeding 80% yielded viscous prepolymers consisting of epoxy-functionalized polymers and residual low-molecular-weight glycidates. These prepolymers were subsequently cured with amines at ambient temperature to form crosslinked networks. The gel fraction exceeded 90% when cured with More > Graphic Abstract

    Partial Oxidation of Diacrylates to Produce Epoxy-Acrylate Hybrid Monomers: Precursors for Ambient-Curable Polymeric Epoxy Resins

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