RENATO SIMÕES CORDEIRO*, WELLERSON RODRIGO SCARANO*, REJANE MAIRA GÓES**, SEBASTIÃO ROBERTO TABOGA**

BIOCELL, Vol.28, No.1, pp. 21-30, 2004, DOI:10.32604/biocell.2004.28.021

Abstract The flutamide antiandrogenic effects on the Guinea pig male prostate morphology in puberal, post-puberal and adult ages were evaluated in the present study. Daily-treated group animals received flutamide subcutaneous injection at a dose of 10 mg/Kg body weight for 10 days. The control group animals received a pharmacological vehicle under the same conditions. The lateral prostate was removed, fixed and processed for light and transmission electron microscopy. The results revealed an increase of the acinus diameter in the treated puberal animals and straitness in the stromal compartment around the acini. The epithelial cells exhibited cubic phenotype. In the post-puberal and… More >

Bhat¹ RB, G Moskovitz²

Phyton-International Journal of Experimental Botany, Vol.78, pp. 67-73, 2009, DOI:10.32604/phyton.2009.78.061

Abstract An investigation of herbal medicinal teas from Western Cape, South Africa was conducted to assess the varieties of herbal teas used to treat various ailments. Each packet of medicinal tea is a blend of carefully selected four or more herbs which are commonly grown in the organic garden in an ancient valley near the southernmost tip of South Africa and some indigenous herbs picked up in the nearby mountains. The teas are specific for the diseased organ/s and also include the herbs to support and strengthen the systems serving the ailing organ/s. The study shows that there are about twenty-one… More >

Marcelo de Castro Pazos*, Cristina Pacheco-Soares*, Newton Soares da Silva*, R.A. DaMatta**, M.T.T. Pacheco*

BIOCELL, Vol.27, No.3, pp. 301-309, 2003, DOI:10.32604/biocell.2003.27.301

Abstract The effects of Photodynamic Therapy using 2^nd generation photosensitizers have been widely investigated aiming clinical application treatment of solid neoplasms. In this work, ultrastructure changes caused by the action of two 2^nd generation photosensitizers and laser irradiation on CHO-K1 and HeLa (neoplastic) cells were analyzed by transmission electron microscopy. Aluminum phthalocyanine chloride, aluminum phthalocyanine tetrasulfonate chloride and radiation from a semiconductor laser at a fluency of 0.5 J/ cm² (Power=26mW; λ=670nm) were used. The results showed induction of apoptosis. Such alterations where observed in HeLa but not in CHO-K1 cells after Aluminum phthalocyanine tetrasulfonate chloride (AlPcS₄) photodynamic treatment. The Aluminum… More >

Longwei Liu¹, Praopim Limsakul¹, Shaoying (Kathy) Lu¹, Peter Yingxiao Wang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 82-82, 2019, DOI:10.32604/mcb.2019.07360

Abstract Genetically-encoded biosensors based on Fluorescence Resonance Energy Transfer (FRET biosensors) have been widely used to dynamically track the activity of Protein Tyrosine Kinases (PTKs) in living cells because of their sensitive ratiometric fluorescence readout, high spatiotemporal resolution. However, the limitation in sensitivity, specificity, and dynamic range of these biosensors have hindered their broader applications, and there was a lack of efficient ways to optimize FRET biosensors. Here we established a rapid, systematic and universal approach for FRET biosensor optimization through directed evolution which involves generating genetic diversity and screening for protein variants with desired properties at the same time and… More >

Yahui Zhang¹, Hui Wang^1,2, Zhouming Mai^1,2, Jianhang Du^1,2,3,*, Guifu Wu^1,2,3

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 85-86, 2019, DOI:10.32604/mcb.2019.05836

Abstract Enhanced external counter pulsation (EECP) is an effective therapy to provide beneficial assistance for the failing heart by reducing cardiac afterload and increasing blood flow perfusion noninvasively. The technique of EECP involves the use of the EECP device to inflate and deflate a series of compression cuffs wrapped around the patient’s calves, lower thighs, and upper thighs. As the result, the enhanced flow perfusion is derived from the device’s propelling blood from veins of lower body to arteries of upper body and increases the blood supply for the important organs and brain. In the ACCF/AHA Guideline and ESC Guideline on… More >

Yesica Romina FRONTINI-LÓPEZ¹, Aldana Daniela GOJANOVICH¹, Diego MASONE^1,2, Diego Martín BUSTOS^1,3, Marina UHART¹

BIOCELL, Vol.42, No.3, pp. 67-78, 2018, DOI:10.32604/biocell.2018.07013

Abstract In the last years, much work has shown that the most effective repair system of the body is represented by stem cells, which are defined as undifferentiated precursors that own unlimited or prolonged self-renewal ability, which also have the potential to transform themselves into various cell types through differentiation.All tissues that form the body contain many different types of somatic cells, along with stem cells that are called ‘mesenchymal stem (or stromal) cells’ (MSC). In certain circumstances, some of these MSC migrate to injured tissues to replace dead cells or to undergo differentiation to repair it.The discovery of MSC has… More >

Mingxu Sun^1,#,*, Yinghang Jiang^2,3,#, Qi Liu^3,4,*, Xiaodong Liu⁴

CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 67-83, 2019, DOI:10.32604/cmc.2019.06079

Abstract A Functional Electrical stimulation (FES) therapy is a common rehabilitation intervention after stroke, and finite state machine (FSM) has proven to be an effective and intuitive FES control method. The FSM uses the data information generated by the accelerometer to robustly trigger state transitions. In the medical field, it is necessary to obtain highly safe and accurate acceleration data. In order to ensure the accuracy of the acceleration sensor data without affecting the accuracy of the motion analysis, we need to perform acceleration big data calibration. In this context, we propose a method for robustly calculating the auto-calibration gain using… More >

Haiping Ye¹, Yongsheng Ding²

CMES-Computer Modeling in Engineering & Sciences, Vol.49, No.3, pp. 255-268, 2009, DOI:10.3970/cmes.2009.049.255

Abstract A fractional-order model for the immunological and therapeutic control of HIV is studied qualitatively. The equilibria are found and their local stability are investigated. Also the global stability of the infection-free equilibrium is established. The optimal efficacy level of anti-retroviral therapy needed to eradicate HIV from the body of an HIV-infected individual is obtained. More >