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  • Open Access

    ARTICLE

    The Epstein-Barr virus-miRNA-BART6-5p regulates TGF-β/SMAD4 pathway to induce glycolysis and enhance proliferation and metastasis of gastric cancer cells

    XUHUI ZHAO1,2, XIAOMIN HUANG1, CHUNYAN DANG2, XIA WANG1, YUJIAO QI3, HONGLING LI2,*

    Oncology Research, Vol.32, No.5, pp. 999-1009, 2024, DOI:10.32604/or.2024.046679

    Abstract Background: EBV-miR-BARTs exhibit significant relevance in epithelial tumors, particularly in EBV-associated gastric and nasopharyngeal cancers. However, their specific mechanisms in the initiation and progression of gastric cancer remain insufficiently explored. Material and Methods: Initially, EBV-miRNA-BART6-5p and its target gene SMAD4 expression were assessed in EBV-associated gastric cancer tissues and cell lines. Subsequent transfection induced overexpression of EBV-miRNA-BART6-5p in AGS and MKN-45, and downregulation in EBV-positive cells (SUN-719). The subsequent evaluation aimed to observe their impact on gastric cancer cell proliferation, migration, and glycolytic processes, with the TGF-β/SMAD4 signaling pathway value clarified using a TGF-β inhibitor. Results: EBV-miRNA-BART6-5p exhibits pronounced upregulation… More >

  • Open Access

    ARTICLE

    Detection of Student Engagement in E-Learning Environments Using EfficientnetV2-L Together with RNN-Based Models

    Farhad Mortezapour Shiri1,*, Ehsan Ahmadi2, Mohammadreza Rezaee1, Thinagaran Perumal1

    Journal on Artificial Intelligence, Vol.6, pp. 85-103, 2024, DOI:10.32604/jai.2024.048911

    Abstract Automatic detection of student engagement levels from videos, which is a spatio-temporal classification problem is crucial for enhancing the quality of online education. This paper addresses this challenge by proposing four novel hybrid end-to-end deep learning models designed for the automatic detection of student engagement levels in e-learning videos. The evaluation of these models utilizes the DAiSEE dataset, a public repository capturing student affective states in e-learning scenarios. The initial model integrates EfficientNetV2-L with Gated Recurrent Unit (GRU) and attains an accuracy of 61.45%. Subsequently, the second model combines EfficientNetV2-L with bidirectional GRU (Bi-GRU), yielding an accuracy of 61.56%. The… More >

  • Open Access

    ARTICLE

    A Hand Features Based Fusion Recognition Network with Enhancing Multi-Modal Correlation

    Wei Wu*, Yuan Zhang, Yunpeng Li, Chuanyang Li, Yan Hao

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 537-555, 2024, DOI:10.32604/cmes.2024.049174

    Abstract Fusing hand-based features in multi-modal biometric recognition enhances anti-spoofing capabilities. Additionally, it leverages inter-modal correlation to enhance recognition performance. Concurrently, the robustness and recognition performance of the system can be enhanced through judiciously leveraging the correlation among multimodal features. Nevertheless, two issues persist in multi-modal feature fusion recognition: Firstly, the enhancement of recognition performance in fusion recognition has not comprehensively considered the inter-modality correlations among distinct modalities. Secondly, during modal fusion, improper weight selection diminishes the salience of crucial modal features, thereby diminishing the overall recognition performance. To address these two issues, we introduce an enhanced DenseNet multimodal recognition network… More > Graphic Abstract

    A Hand Features Based Fusion Recognition Network with Enhancing Multi-Modal Correlation

  • Open Access

    ARTICLE

    Effect of Modulus Heterogeneity on the Equilibrium Shape and Stress Field of α Precipitate in Ti-6Al-4V

    Di Qiu1,3,4, Rongpei Shi2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1017-1028, 2024, DOI:10.32604/cmes.2024.048797

    Abstract For media with inclusions (e.g., precipitates, voids, reinforcements, and others), the difference in lattice parameter and the elastic modulus between the matrix and inclusions cause stress concentration at the interfaces. These stress fields depend on the inclusions’ size, shape, and distribution and will respond instantly to the evolving microstructure. This study develops a phase-field model concerning modulus heterogeneity. The effect of modulus heterogeneity on the growth process and equilibrium state of the α plate in Ti-6Al-4V during precipitation is evaluated. The α precipitate exhibits strong anisotropy in shape upon cooling due to the interplay of the elastic strain and interfacial… More >

  • Open Access

    ARTICLE

    DCFNet: An Effective Dual-Branch Cross-Attention Fusion Network for Medical Image Segmentation

    Chengzhang Zhu1,2, Renmao Zhang1, Yalong Xiao1,2,*, Beiji Zou1, Xian Chai1, Zhangzheng Yang1, Rong Hu3, Xuanchu Duan4

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1103-1128, 2024, DOI:10.32604/cmes.2024.048453

    Abstract Automatic segmentation of medical images provides a reliable scientific basis for disease diagnosis and analysis. Notably, most existing methods that combine the strengths of convolutional neural networks (CNNs) and Transformers have made significant progress. However, there are some limitations in the current integration of CNN and Transformer technology in two key aspects. Firstly, most methods either overlook or fail to fully incorporate the complementary nature between local and global features. Secondly, the significance of integrating the multi-scale encoder features from the dual-branch network to enhance the decoding features is often disregarded in methods that combine CNN and Transformer. To address… More >

  • Open Access

    ARTICLE

    A Lightweight Network with Dual Encoder and Cross Feature Fusion for Cement Pavement Crack Detection

    Zhong Qu1,*, Guoqing Mu1, Bin Yuan2

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 255-273, 2024, DOI:10.32604/cmes.2024.048175

    Abstract Automatic crack detection of cement pavement chiefly benefits from the rapid development of deep learning, with convolutional neural networks (CNN) playing an important role in this field. However, as the performance of crack detection in cement pavement improves, the depth and width of the network structure are significantly increased, which necessitates more computing power and storage space. This limitation hampers the practical implementation of crack detection models on various platforms, particularly portable devices like small mobile devices. To solve these problems, we propose a dual-encoder-based network architecture that focuses on extracting more comprehensive fracture feature information and combines cross-fusion modules… More > Graphic Abstract

    A Lightweight Network with Dual Encoder and Cross Feature Fusion for Cement Pavement Crack Detection

  • Open Access

    ARTICLE

    Reliable Data Collection Model and Transmission Framework in Large-Scale Wireless Medical Sensor Networks

    Haosong Gou1, Gaoyi Zhang1, Renê Ripardo Calixto2, Senthil Kumar Jagatheesaperumal3, Victor Hugo C. de Albuquerque2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1077-1102, 2024, DOI:10.32604/cmes.2024.047806

    Abstract Large-scale wireless sensor networks (WSNs) play a critical role in monitoring dangerous scenarios and responding to medical emergencies. However, the inherent instability and error-prone nature of wireless links present significant challenges, necessitating efficient data collection and reliable transmission services. This paper addresses the limitations of existing data transmission and recovery protocols by proposing a systematic end-to-end design tailored for medical event-driven cluster-based large-scale WSNs. The primary goal is to enhance the reliability of data collection and transmission services, ensuring a comprehensive and practical approach. Our approach focuses on refining the hop-count-based routing scheme to achieve fairness in forwarding reliability. Additionally,… More >

  • Open Access

    ARTICLE

    A Random Fusion of Mix3D and PolarMix to Improve Semantic Segmentation Performance in 3D Lidar Point Cloud

    Bo Liu1,2, Li Feng1,*, Yufeng Chen3

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 845-862, 2024, DOI:10.32604/cmes.2024.047695

    Abstract This paper focuses on the effective utilization of data augmentation techniques for 3D lidar point clouds to enhance the performance of neural network models. These point clouds, which represent spatial information through a collection of 3D coordinates, have found wide-ranging applications. Data augmentation has emerged as a potent solution to the challenges posed by limited labeled data and the need to enhance model generalization capabilities. Much of the existing research is devoted to crafting novel data augmentation methods specifically for 3D lidar point clouds. However, there has been a lack of focus on making the most of the numerous existing… More >

  • Open Access

    ARTICLE

    Deep Learning Social Network Access Control Model Based on User Preferences

    Fangfang Shan1,2,*, Fuyang Li1, Zhenyu Wang1, Peiyu Ji1, Mengyi Wang1, Huifang Sun1

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1029-1044, 2024, DOI:10.32604/cmes.2024.047665

    Abstract A deep learning access control model based on user preferences is proposed to address the issue of personal privacy leakage in social networks. Firstly, social users and social data entities are extracted from the social network and used to construct homogeneous and heterogeneous graphs. Secondly, a graph neural network model is designed based on user daily social behavior and daily social data to simulate the dissemination and changes of user social preferences and user personal preferences in the social network. Then, high-order neighbor nodes, hidden neighbor nodes, displayed neighbor nodes, and social data nodes are used to update user nodes… More >

  • Open Access

    ARTICLE

    Identifying Brand Consistency by Product Differentiation Using CNN

    Hung-Hsiang Wang1, Chih-Ping Chen2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 685-709, 2024, DOI:10.32604/cmes.2024.047630

    Abstract This paper presents a new method of using a convolutional neural network (CNN) in machine learning to identify brand consistency by product appearance variation. In Experiment 1, we collected fifty mouse devices from the past thirty-five years from a renowned company to build a dataset consisting of product pictures with pre-defined design features of their appearance and functions. Results show that it is a challenge to distinguish periods for the subtle evolution of the mouse devices with such traditional methods as time series analysis and principal component analysis (PCA). In Experiment 2, we applied deep learning to predict the extent… More >

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