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  • Open Access

    ARTICLE

    Detection of new antibiotic resistance gene profile in Escherichia coli associated with avian leukosis virus infection from broiler chickens

    HAIFENG WANG1,2,*, JUAN GUO1, LIJING ZHENG1, SHUYING LIU1, ZHERONG WANG1, HONGXUAN HE2

    BIOCELL, Vol.44, No.2, pp. 217-224, 2020, DOI:10.32604/biocell.2020.09051

    Abstract The Escherichia coli (E. coli) is prevailing worldwide, but the epidemiology of E. coli infections feature regional distribution characteristics to some extent. E. coli, as a zoonotic pathogen, can be transferred from animals to humans through food chain or via contact with wounds, causing a public health risk. We reported the swelling of proventriculus and tracheal bleeding following the death in two broiler chickens (Gallus gallus domesticus) from Beijing, China. To investigate whether a virus was involved in the infection, Madin Darby Bovine Kidney (MDCK) cells were co-cultured with supernatants of proventriculus, trachea and spleen homogenates. The avian leucosis virus… More >

  • Open Access

    REVIEW

    Updated thoughts on SARS-CoV-2 and coronavirus therapies, fighting and surviving

    WENJUAN LI*, GE SONG

    BIOCELL, Vol.44, No.2, pp. 127-135, 2020, DOI:10.32604/biocell.2020.010018

    Abstract From late December 2019 a new human-adapted coronavirus, SARS-CoV-2, was observed and isolated in clustered patients in Wuhan, China. It has been proved to be able to transmit human-to-human and cause pneumonia, leading to about 2% fatality. Its genome characteristics, immune responses and related potential treatments, such as chemical drugs, serum transfusion and vaccines including DNA vaccines, are discussed in this review for a brief summary. More >

  • Open Access

    ARTICLE

    Why Ignore the Dark Side of Social Media? A Role of Social Media in Spreading Corona-Phobia and Psychological Well-Being

    Saqib Amin*

    International Journal of Mental Health Promotion, Vol.22, No.1, pp. 29-38, 2020, DOI:10.32604/IJMHP.2020.011115

    Abstract Coronaviruses are a category of associated viruses that trigger disease in mammals and birds. Human coronaviruses have been identified including severe acute respiratory syndrome-related coronavirus (SARS-CoV) in 2003, human coronavirus NL63 (HCoV NL63) in 2004, human coronavirus HKU1 (HKU1) in 2005, Middle East respiratory syndrome-related coronavirus (MERSCoV) in 2012, and severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) in December, 2019. This study aims to examine whether social media at residing/admittance in quarantine ward (due to corona virus pandemic disease) affects psychological health or not? We asked questions from 250 quarantined patients infected from coronavirus (restricted to quarantine ward) about their psychological… More >

  • Open Access

    ARTICLE

    Towards an Artificial Intelligence Framework for Data-Driven Prediction of Coronavirus Clinical Severity

    Xiangao Jiang1, Megan Coffee2, 3, *, Anasse Bari4, *, Junzhang Wang4, Xinyue Jiang5, Jianping Huang1, Jichan Shi1, Jianyi Dai1, Jing Cai1, Tianxiao Zhang6, Zhengxing Wu1, Guiqing He1, Yitong Huang7

    CMC-Computers, Materials & Continua, Vol.63, No.1, pp. 537-551, 2020, DOI:10.32604/cmc.2020.010691

    Abstract The virus SARS-CoV2, which causes coronavirus disease (COVID-19) has become a pandemic and has spread to every inhabited continent. Given the increasing caseload, there is an urgent need to augment clinical skills in order to identify from among the many mild cases the few that will progress to critical illness. We present a first step towards building an artificial intelligence (AI) framework, with predictive analytics (PA) capabilities applied to real patient data, to provide rapid clinical decision-making support. COVID-19 has presented a pressing need as a) clinicians are still developing clinical acumen to this novel disease and b) resource limitations… More >

  • Open Access

    ARTICLE

    Association of TRIM22 with the type 1 interferon response during primary human cytomegalovirus infection in THP-1 macrophages

    Wei LI, Huihui GAO, Ran TAO, Lifang LIU, Shiqiang SHANG*

    BIOCELL, Vol.43, No.4, pp. 285-291, 2019, DOI:10.32604/biocell.2019.08177

    Abstract As a response factor of interferon, tripartite motif (TRIM) 22 was reported to exert antiviral activity against viruses. In this study, THP-1 macrophages were infected with human cytomegalovirus (HCMV) to establish the HCMV lytic infection model. The mRNA levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and interferonbeta (IFN-β) were significantly up-regulated in THP-1 macrophages at different infection time and titers. Moreover, for the first time, upregulation of TRIM22 expression was found during HCMV infection at both mRNA and protein levels in THP-1 macrophages. Furthermore, IFN-β could induce TRIM22 expression in THP-1 macrophages or HCMV infected THP-1 macrophages. Depletion of… More >

  • Open Access

    ARTICLE

    Numerical Simulations for Stochastic Computer Virus Propagation Model

    Muhammad Shoaib Arif1, *, Ali Raza1, Muhammad Rafiq2, Mairaj Bibi3, Javeria Nawaz Abbasi3, Amna Nazeer3, Umer Javed4

    CMC-Computers, Materials & Continua, Vol.62, No.1, pp. 61-77, 2020, DOI:10.32604/cmc.2020.08595

    Abstract We are presenting the numerical simulations for the stochastic computer virus propagation model in this manuscript. We are comparing the solutions of stochastic and deterministic computer virus models. Outcomes of a threshold number R0 hold in stochastic computer virus model. If R0 < 1 then in such a condition virus controlled in the computer population while R0 > 1 shows virus rapidly spread in the computer population. Unfortunately, stochastic numerical techniques fail to cope with large step sizes of time. The suggested structure of the stochastic non-standard finite difference technique can never violate the dynamical properties. On this basis, we… More >

  • Open Access

    ARTICLE

    Apoptosis as pathogenic mechanism of infection with vesicular stomatitis virus. Evidence in primary bovine fibroblast cultures

    A. LÓPEZ-HERRERA1*, J. RUIZ-SÁENZ2, Y.P. GÓEZ3, W. ZAPATA3, P.A. VELILLA3, A.E. ARANGO3, S. URCUQUI-INCHIMA3

    BIOCELL, Vol.33, No.2, pp. 121-132, 2009, DOI:10.32604/biocell.2009.33.121

    Abstract To determine whether fibroblasts from Blanco Orejinegro cattle, exhibit any level of resistance to infection against vesicular stomatitis virus (VSV) serotypes Indiana (VSV-I) or New Jersey (VSVNJ), 30 fibroblast cultures were phenotyped to evaluate their resistance/susceptibility. Thirty three % of Blanco Orejinegro fibroblast cultures were classified as very resistant, 50% as resistant, and 17% as susceptible to VSV-I infection, whereas 20% were classified as very resistant, 50% as resistant and 30% as susceptible to VSV-NJ infection. Therefore, there appears to be a large variation in phenotypic polymorphism among the fibroblasts to infection by VSV. To elucidate the mechanisms responsible for… More >

  • Open Access

    ARTICLE

    Brief Note: Natural infection of Viola cornuta (Violaceae) with Cucumber mosaic virus, subgroup I

    JOEL ARNEODO*, SOLEDAD DE BREUIL*, SERGIO LENARDON**, LUIS CONCI**

    BIOCELL, Vol.29, No.2, pp. 205-207, 2005, DOI:10.32604/biocell.2005.29.205

    Abstract Plants of Viola cornuta displaying typical virus symptoms were observed during spring 2003 in a plant nursery in Córdoba, central Argentina. Electron microscopic examinations of symptomatic leaf samples revealed the presence of isometric virus-like particles about 30 nm in diameter. Subsequent serological analysis allowed the identification of the pathogen as a subgroup I strain of Cucumber mosaic virus (CMV). These results were confirmed by antigen capture - reverse transcription - polymerase chain reaction with specific CMV primers, and digestion with a restriction enzyme. This is the first report of CMV infecting V. cornuta in Argentina. More >

  • Open Access

    ARTICLE

    Turnip mosaic virus infecting kale plants in Ordu, Turkey

    Sevik MA

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 231-235, 2016, DOI:10.32604/phyton.2016.85.231

    Abstract Brassica oleracea var. acephala L. (kale) is widely grown in the Black Sea Region of Turkey. Kale growing has not been common in the other regions of Turkey. A number of diseases can seriously affect Brassica crop production. Field surveys were done to determine the occurrence of viruses in kale-growing areas in Ordu in 2013-2014. Leaf samples were collected from kale plants and tested for the presence of Turnip mosaic virus (TuMV), Cauliflower mosaic virus (CaMV), Turnip yellow mosaic virus (TYMV), and Cucumber mosaic virus (CMV) by DAS-ELISA and bioassays. Result of serological and biological tests showed that 7.7% of… More >

  • Open Access

    ARTICLE

    SCAR molecular markers to identify disease resistance sources in ayocote beans (Phaseolus coccineus)

    Ruíz-Salazar R1, JS Muruaga-Martínez2, MLP Vargas-Vázquez2, G Alejandre-Iturbide4, G Castañón-Nájera3, S Hernández-Delgado1, N Almaraz-Abarca4, N Mayek-Pérez1,5

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 184-193, 2016, DOI:10.32604/phyton.2016.85.184

    Abstract In order to identify genes of resistance to four diseases that affect Phaseolus sp. [i.e, Common Bacterial Blight (CBB), Bean Common Mosaic Virus (BCMV), Bean Golden Mosaic Virus (BGMV) and angular leaf spot (ALS)], we amplified nine SCAR (Sequence Characterized Amplified Regions) markers: four linked to resistance to common blight, two for BCMV, two for BGMV and one for ALS. The genetic material included 16 ayocote bean (P. coccineus) populations collected from different locations at Veracruz and Puebla, Mexico. Populations from Veracruz showed greater number of SCARs for BGMV and ALS compared with populations from Puebla. The best P. coccineusMore >

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