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  • Open Access

    ARTICLE

    Stability Analysis of Predator-Prey System with Consuming Resource and Disease in Predator Species

    Asad Ejaz1, Yasir Nawaz1, Muhammad Shoaib Arif1,3,*, Daoud S. Mashat2, Kamaleldin Abodayeh3

    CMES-Computer Modeling in Engineering & Sciences, Vol.132, No.2, pp. 489-506, 2022, DOI:10.32604/cmes.2022.019440

    Abstract The present study is concerned with formulating a predator-prey eco-epidemiological mathematical model assuming that an infection exists in the predator species. The two classes of predator species (susceptible and infected) compete for the same sources available in the environment with the predation option. It is assumed that the disease does not spread vertically. The proposed model is analyzed for the stability of the coexistence of the predators and prey. The fixed points are carried out, and the coexisting fixed point is studied in detail by constructing the Lyapunov function. The movement of species in search of food or protection in… More >

  • Open Access

    ARTICLE

    An Adaptive Real-Time Third Order Sliding Mode Control for Nonlinear Systems

    Ahmed M. Elmogy1,2,*, Amany Sarhan2, Wael M. Elawady2

    CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5629-5641, 2022, DOI:10.32604/cmc.2022.025247

    Abstract As most real world systems are significantly nonlinear in nature, developing robust controllers have attracted many researchers for decades. Robust controllers are the controllers that are able to cope with the inherent uncertainties of the nonlinear systems. Many control methods have been developed for this purpose. Sliding mode control (SMC) is one of the most commonly used methods in developing robust controllers. This paper presents a higher order SMC (HOSMC) approach to mitigate the chattering problem of the traditional SMC techniques. The developed approach combines a third order SMC with an adaptive PID (proportional, integral, derivative) sliding surface to overcome… More >

  • Open Access

    ARTICLE

    CDK5 inhibition promotes osteoblastic differentiation of MSCs and blocks the migration of osteosarcoma MG-63 cells

    HONG FU1, HAOYU ZHAO1, YALI YANG1, SIYU WANG1, KE DUAN2,*, TAILIN GUO1,*

    BIOCELL, Vol.46, No.4, pp. 1067-1078, 2022, DOI:10.32604/biocell.2022.017435

    Abstract CDK5 belongs to the cyclin-dependent kinase family. CDK5 is multifunctional and plays an important role in neural differentiation. However, the role of CDK5 in osteoblastic differentiation remains unclear. The present study investigated functions and molecular mechanism of CDK5 in osteoblastic differentiation. It was found that, CDK5 inhibition promoted the expression of Runx2, ALP, OCN and OPN of MSCs and the mineralization of MC-3T3E1 cells and MSCs. CDK5 inhibition enhanced the development of F-actin, nuclear localization of β-catenin and YAP, as well as the expression of RMRP RNA. When F-actin was suppressed by Blebbistatin, the nuclear localization of YAP and β-catenin,… More >

  • Open Access

    ARTICLE

    Mechanical and histological properties of an electrospun scaffold with a modified surface by plasma polymerization implanted in an in vivo model

    MARÍA G. FLORES-SÁNCHEZ1,*, ROBERTO OLAYO2, J. MORALES-CORONA2, ATLÁNTIDA M. RAYA-RIVERA3, DIEGO R. ESQUILIANO-RENDÓN3

    BIOCELL, Vol.46, No.3, pp. 829-836, 2022, DOI:10.32604/biocell.2022.016988

    Abstract This article presents the construction of scaffolds composed of polylactic acid (PLA) with different concentrations of hydroxyapatite (HA) by electrospinning, which were superficially modified with polypyrrole (PPy/I) by plasma polymerization. A preliminary study was conducted of the biological and mechanical behavior of the scaffolds when they were implanted in the back of rabbits for 30 days; bone cells differentiated from mesenchymal stem cells (MSCs) were used. The bone cell and scaffold structures were characterized by histological, immunohistochemical, and mechanical stress tests. Hematoxylin–eosin staining showed good tissue conformation. The immunohistochemical tests highlighted the presence of the main bone tissue proteins, such… More >

  • Open Access

    ARTICLE

    Dynamic Sliding Mode Backstepping Control for Vertical Magnetic Bearing System

    Wei-Lung Mao1,*, Yu-Ying Chiu1, Chao-Ting Chu2, Bing-Hong Lin1, Jian-Jie Hung3

    Intelligent Automation & Soft Computing, Vol.32, No.2, pp. 923-936, 2022, DOI:10.32604/iasc.2022.019555

    Abstract Electromagnets are commonly used as support for machine components and parts in magnetic bearing systems (MBSs). Compared with conventional mechanical bearings, the magnetic bearings have less noise, friction, and vibration, but the magnetic force has a highly nonlinear relationship with the control current and the air gap. This research presents a dynamic sliding mode backstepping control (DSMBC) designed to track the height position of modeless vertical MBS. Because MBS is nonlinear with model uncertainty, the design of estimator should be able to solve the lumped uncertainty. The proposed DSMBC controller can not only stabilize the nonlinear system under mismatched uncertainties,… More >

  • Open Access

    ARTICLE

    Position Control of Flexible Joint Carts Using Adaptive Generalized Dynamics Inversion

    Ibrahim M. Mehedi1,2,*, Mohd Heidir Mohd Shah1 , Soon Xin Ng3 , Abdulah Jeza Aljohani1,2, Mohammed El-Hajjar3, Muhammad Moinuddin1,2

    CMC-Computers, Materials & Continua, Vol.70, No.3, pp. 4691-4705, 2022, DOI:10.32604/cmc.2022.020954

    Abstract

    This paper presents the design and implementation of Adaptive Generalized Dynamic Inversion (AGDI) to track the position of a Linear Flexible Joint Cart (LFJC) system along with vibration suppression of the flexible joint. The proposed AGDI control law will be comprised of two control elements. The baseline (continuous) control law is based on principle of conventional GDI approach and is established by prescribing the constraint dynamics of controlled state variables that reflect the control objectives. The control law is realized by inverting the prescribed dynamics using dynamically scaled Moore-Penrose generalized inversion. To boost the robust attributes against system nonlinearities, parametric… More >

  • Open Access

    ARTICLE

    Lyapunov-Redesign and Sliding Mode Controller for Microprocessor Based Transfemoral Prosthesis

    Ali Murtaza1, Muhammad Usman Qadir1, Muhammad Awais Khan1, Izhar ul Haq1,*, Kamran Shah1, Nizar Akhtar2

    Intelligent Automation & Soft Computing, Vol.31, No.3, pp. 1887-1899, 2022, DOI:10.32604/iasc.2022.020006

    Abstract Transfemoral prostheses have evolved from mechanical devices to microprocessor-based, electronically controlled knee joints, allowing amputees to regain control of their limbs. For improved amputee experience at varying ambulation rates, these devices provide controlled damping throughout the swing and stance phases of the gait cycle. Commercially available microprocessor-based prosthetic knee (MPK) joints use linear controllers, heuristic-based methods, and finite state machine based algorithms to track the refence gait cycle. However, since the amputee experiences a variety of non-linearities during ambulation, such as uneven terrains, walking backwards and climbing stairs, therefore, traditional controllers produces error, abnormal movements, unstable control system and require… More >

  • Open Access

    ARTICLE

    Robust Speed Regulation of Induction Motor Subjected to Unknown Load Torque

    H. Abdelfattah1, A. A. Abouelsoud2, Fahd A. Banakhr3, Mohamed I. Mosaad3,*

    Intelligent Automation & Soft Computing, Vol.31, No.1, pp. 591-605, 2022, DOI:10.32604/iasc.2022.018765

    Abstract Induction motors are still the most used in industrial applications due to the simplicity of installation and low maintenance cost, especially for the squirrel cage type. The significant development in power electronics in terms of high-speed technologies in power electronic switches, their availability in high ratings, and the considerable decrease in the cost of the power electronics components supports this increase in uses. However, changing the induction motor's speed with loading, load torque measurement devices, and speed sensors limit this increase in using such motors. This paper proposes a state feedback controller-based backstepping technique for robust speed regulators of induction… More >

  • Open Access

    ARTICLE

    Using Big Data to Discover Chaos in China’s Futures Market During COVID-19

    Lin Tie1, Bin Huang1, Bin Pan1, Guang Sun1,2,*

    CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 3095-3107, 2021, DOI:10.32604/cmc.2021.019363

    Abstract COVID-19 was first reported in China and quickly spread throughout the world. Weak investor confidence in government efforts to control the pandemic seriously affected global financial markets. This study investigated chaos in China’s futures market during COVID-19, focusing on the degree of chaos at different periods during the pandemic. We constructed a phase diagram to observe the attractor trajectory of index futures (IFs). During the COVID-19 outbreak, overall chaos in China’s futures market was increasing, and there was a clear correlation between market volatility and the macroenvironment (mainly government regulation). The Hurst index, calculated by rescaled range (R/S) analysis, was… More >

  • Open Access

    ARTICLE

    Mir-612 Inhibits Proliferation and Invasion of Urothelial Carcinoma of Bladder Cells through Activating Hippo Pathway via Targeting PMEPA1

    Peng Wang, Haiyang Zhang, Zilian Cui, Xunbo Jin*, Dong Zhang*

    Oncologie, Vol.23, No.2, pp. 259-268, 2021, DOI:10.32604/Oncologie.2021.015503

    Abstract Urothelial carcinoma of bladder (UCB) is a common urological malignancy in the world, but its progression mechanism remains unclear. MiR-612 was found as an anti-tumor factor in multiple types of cancer, while few studies have revealed its functions in UCB cells. Based on this, UCB cells such as HTB-9 and HTB-4, and normal urothelial of bladder cells such as SV-Huc1, were used as subjects in this study. Western blot, qRTPCR, CCK-8 assay and transwell assay were used to assess functions of miR-612 in UCB cells. The database, miRWalk, was used to search for potential targets of miR-612, and dual-luciferase reporter… More >

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