Chenxuan Zhang, Yongqing Qi^*, Ximin Cao, Yanchi Zhang

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.069878 - 27 January 2026

Abstract To enhance the low-carbon economic efficiency and increase the utilization of renewable energy within integrated energy systems (IES), this paper proposes a low-carbon dispatch model integrating power-to-gas (P2G), carbon capture and storage (CCS), hydrogen fuel cell (HFC), and combined heat and power (CHP). The P2G process is refined into a two-stage structure, and HFC is introduced to enhance hydrogen utilization. Together with CCS and CHP, these devices form a multi-energy conversion system coupling electricity, heat, cooling, and gas. A ladder-type carbon trading approach is adopted to flexibly manage carbon output by leveraging marginal cost adjustments.… More >

Xiaoyu Zhang^1,#, RenFei Zong^1,#, Yan Sun¹, Nan Chen², Kunyao Zhu¹, Hang Tong¹, Tinghao Li¹, Junlong Zhu¹, Zijia Qin¹, Linfeng Wu¹, Aimin Wang¹, Weiyang He^1,*

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.072084 - 19 January 2026

Abstract Objective: While cisplatin-based chemotherapy is pivotal for advanced bladder cancer, acquired resistance remains a major obstacle. This study investigates key molecular drivers of this resistance and potential reversal strategies. Methods: We established GC (Gemcitabine and Cisplatin)-resistant T24-R and UC3-R cell lines from T24 and UM-UC-3 (UC3) cells. Transcriptomic and proteomic analyses identified differentially expressed molecules. Apoptosis and cell viability were assessed by flow cytometry and CCK-8 (Cell Counting Kit-8) assays, while RT-qPCR (Reverse Transcription Quantitative Polymerase Chain Reaction) and Western blot analyzed gene and protein expression. Immunofluorescence evaluated FAK (Focal Adhesion Kinase) phosphorylation, and a… More >

Jingshuai Pang^1,2, Songcen Wang¹, Hongyin Chen^1,2,*, Xiaoqiang Jia¹, Yi Guo¹, Ling Cheng¹, Xinhe Zhang¹, Jianfeng Li¹

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.070256 - 27 December 2025

Abstract To achieve the goals of sustainable development of the energy system and the construction of a low-carbon society, this study proposes a multi-energy storage collaborative optimization strategy for industrial park that integrates the laddered carbon trading mechanism with demand response. Firstly, a dual dimensional DR model is constructed based on the characteristics of load elasticity. The alternative DR enables flexible substitution of energy loads through complementary conversion of electricity/heat/cold multi-energy sources, while the price DR relies on time-of-use electricity price signals to guide load spatiotemporal migration; Secondly, the LCT mechanism is introduced to achieve optimal… More >

Song Xu^1,2,3,4,5,*, Mengxin Lu^1,2,3,4,5, Zhonghua Yang^1,2,3,4,5, Hang Zheng^1,2,3,4,5

Canadian Journal of Urology, Vol.32, No.6, pp. 579-588, 2025, DOI:10.32604/cju.2025.063069 - 30 December 2025

Abstract Background: Many studies have evaluated the performance of fluorescence in situ hybridization (FISH) in detecting urothelial carcinoma, while few of them compared it in detecting bladder cancer (BC) vs. upper tract urothelial carcinoma (UTUC). This study aimed to determine and compare the FISH performance in detecting BC and UTUC. Methods: Data of patients with suspected urothelial carcinoma (UC) who accepted FISH from January 2021 to April 2023 were retrieved. The sensitivity and specificity of FISH in detecting BC and UTUC were determined and compared. Results: A total of 145 BC, 62 UTUC, and 170 non-UC patients were… More >

Raidizon Mercedes, Eric Eidelman, Michael Mawhorter, Max Yudovich, Alireza Aminsharifi^*

Canadian Journal of Urology, Vol.32, No.5, pp. 515-520, 2025, DOI:10.32604/cju.2025.067973 - 30 October 2025

Abstract Background: Spontaneous rupture of the urinary bladder (SRUB) is a rare condition characterized by bladder rupture without any trauma or previous instrumentation. Diagnosing SRUB can be challenging, leading to potential delays in treatment and significant morbidity. Case description: We present a case of a 75-year-old male with a complex medical history, including atrial fibrillation, systemic lupus erythematosus, antiphospholipid syndrome, and chronic anticoagulation, who developed sudden onset gross hematuria and abdominal pain following bilateral internal iliac artery angioembolization for a spontaneous pelvic hematoma in the setting of supratherapeutic anticoagulation. Extraperitoneal bladder perforation was confirmed by CT cystogram.… More >

Lihao Zhang^1,2, Lin Cao^1,2, Lige Huang^1,2, Jie Wang^1,2, Jiabing Li^2,3,*

Canadian Journal of Urology, Vol.32, No.5, pp. 457-468, 2025, DOI:10.32604/cju.2025.067364 - 30 October 2025

Abstract Background: Studies have indicated an association between inflammatory factors (IFs) in the blood and the development of bladder cancer (BC). This study aimed to explore the correlation and clinical significance of IFs with the pathological grading of BC. Methods: A retrospective analysis was conducted on the preoperative blood routine results, postoperative pathological findings, and baseline information of 163 patients. Patients were divided into high-grade and low-grade groups based on pathological grading. Group comparisons and logistic regression analyses were performed using R software version 4.1.3 to explore the relationships between IFs and BC pathological grading. Results: The… More >

Azik Hoffman^1,2,*, Eyal Kochavi³, Gilad E. Amiel^1,2

Canadian Journal of Urology, Vol.32, No.5, pp. 423-432, 2025, DOI:10.32604/cju.2025.064740 - 30 October 2025

Abstract Objectives: Initial treatment for Non-Muscle Invasive Bladder Cancer (NMIBC) has remained mostly unchanged in recent decades. Cryotherapy with CO₂ has been commonly used in medicine for many years. In this study, we present the results of a pre-clinical study aimed at developing a novel cryoablation device to treat superficial low-grade bladder lesions. Methods: Following initial technical and developmental studies, a rigid cryotherapy device was developed. A technical and efficacy assessment was conducted utilizing the porcine model. Overall, twenty-six ablation areas (up to four per animal) were evaluated. Following an initial routine cystoscopy, the bladder irrigation medium… More >

Ozgu Aydogdu^1,*, Onur Erdemoglu², Halil Ibrahim Bozkurt², Tansu Degirmenci², Michael Winder³

Canadian Journal of Urology, Vol.32, No.5, pp. 529-538, 2025, DOI:10.32604/cju.2025.064564 - 30 October 2025

Abstract Objectives: Treatment of patients with lower urinary tract symptoms (LUTS) is often challenging. In men, the origin of LUTS, in particular overactive bladder (OAB) symptoms, is often due to prostate enlargement. However, patients with chronic prostate inflammation (CPI) also frequently experience OAB. Thus far, it is not known if the inflammation per se or concomitant prostate enlargement is the underlying cause of LUTS. Currently, we aim to examine if there is any correlation between CPI and the persistence of OAB symptoms in patients with benign prostate hyperplasia (BPH). Methods: Fifty-one men underwent transurethral resection of… More >

Marie Chaumel¹, Nicolas Brichart², Franck Bruyère¹, Ali Bourgi^1,*

Canadian Journal of Urology, Vol.32, No.4, pp. 359-366, 2025, DOI:10.32604/cju.2025.066470 - 29 August 2025

Abstract Background: The COVID-19 pandemic disrupted healthcare systems globally, raising concerns about delayed cancer diagnosis and treatment. In France, transurethral resection of bladder tumors (TURBT) was prioritized in national urology guidelines to ensure the timely management of urothelial carcinoma. This study aimed to assess the impact of care reorganization on tumor staging, recurrence, palliative care, and mortality in bladder cancer patients from the pre-pandemic through late-pandemic periods. Methods: We conducted a retrospective multicenter study including all patients who underwent TURBT with histologically confirmed urothelial carcinoma between April and December of 2019 (pre-pandemic), 2020 (early pandemic), 2021… More >

Matthew S. Lee, Trey R. Sledge, Amanda K. Seyer, Robert Qi, Kevin Koo^*

Canadian Journal of Urology, Vol.32, No.4, pp. 325-333, 2025, DOI:10.32604/cju.2025.064255 - 29 August 2025

Abstract While cystolitholapaxy for bladder stones is commonly performed using a transurethral approach, large or complex stone burdens in patients with complex lower urinary tract anatomy may make this inefficient or infeasible. Percutaneous cystolitholapaxy is a safe, effective, minimally invasive alternative for diverse indications, including patients with benign prostatic hyperplasia, urethral stricture disease, closed bladder neck, continent catheterized channel, or other urinary diversion. In this article, we review the indications for and advantages of percutaneous cystolitholapaxy and describe our step-by-step technique for this procedure, including representative imaging and favored equipment. We also discuss preoperative and postoperative More >