Xuesong Wang^1,#, Zhihong Wang^1,2,#, Qiuling Yang¹, Sheng Peng³, Mijun Peng^1,*

Journal of Renewable Materials, Vol.10, No.12, pp. 3131-3145, 2022, DOI:10.32604/jrm.2022.020204

Abstract To evaluate the potential anti-aging ability of Eucommia ulmoides, four characteristic components (chlorogenic acid, geniposidic acid, aucubin, quercetin) were selected to assess their effects on H2O2-induced oxidative damage model of human umbilical vein endothelial cell (HUVEC). Oxidative damage indexes, inflammatory factors, cell cycle, cell apoptosis, cell senescence, and their related proteins were analyzed by methyl thiazolyl tetrazolium (MTT) assay, enzyme-linked immunosorbent assay (ELISA), propidium iodide (PI) staining, annexin V-FITC/ PI double staining, SA β-galactosidase staining, and western blotting (WB). The results showed that H2O2- induced cell growth inhibition rate decreased as supplementation with characteristic components when compared to H2O2 group.… More >

Chengjie Shu¹, Mengli Zhang¹, Weiming Zhang¹, Shihong Ma¹, Guoqing Chen² and Baojun Shi^1,*

Phyton-International Journal of Experimental Botany, Vol.88, No.3, pp. 317-324, 2019, DOI:10.32604/phyton.2019.07766

Abstract Zanthoxylum schinifolium has been used as spices and traditional medicine in China for hundreds of years. A variety of active substances have been isolated from Zanthoxylum schinifolium using biological and chemical techniques. Among these substances, the effect of schinifoline has gradually attracted much attention. Candida albicans is one of the most common pathogens isolated from the gastrointestinal tract, vagina, and mouth in healthy individuals. In a healthy population, there are various mechanisms in host, such as the microbial flora, the epithelial barriers, and the innate immune system, that can control the presence of Candida albicans. However, when host immunity is… More >