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  • Open Access

    ARTICLE

    Combinatory effect of hesperetin and mesenchymal stem cells on the deteriorated lipid profile, heart and kidney functions and antioxidant activity in STZ-induced diabetic rats

    Osama M. AHMED1, Mohamed A. HASSAN2, Ablaa S. SALEH2

    BIOCELL, Vol.44, No.1, pp. 27-29, 2020, DOI:10.32604/biocell.2020.08040

    Abstract This study aimed to assess the effect of hesperetin and/or bone marrow-derived mesenchymal stem cells (BM-MSCs) on disturbed lipid profile, heart and kidney functions, oxidative stress and antioxidant defense system in streptozotocin (STZ)-induced diabetic rats. Type 1 diabetes mellitus (T1DM) was induced in male Wistar rats by injecting 40 mg/kg body weight (b.w.) STZ dissolved in citrate buffer (pH 4.5). The diabetic rats were treated with hesperetin orally administered at dose 20 mg/kg b.w., BM-MSCs intravenously injected at a dose of 1 x 106 cells/ rat/week and their combination for 6 weeks. The diabetic rats exhibited lipid abnormalities manifested by… More >

  • Open Access

    ARTICLE

    Structural Characterization and Antioxidant Activity of Lignin Extracted from Ficus Carica L.

    Ibtissem Moussa1,2, Ramzi Khiari1,3,4,*, Ali Moussa2, Gérard Mortha4, Mohamed Farouk Mhenni1

    Journal of Renewable Materials, Vol.7, No.4, pp. 345-354, 2019, DOI:10.32604/jrm.2019.04011

    Abstract The most abundant phenolic biopolymer in the biosphere is the lignin. This phenolic biopolymer commonly exists in combination with polysaccharides and other cell wall components. In this study, the solvent system dioxane-water is used to extract lignin, which is considered as unaltered native lignin. The dioxane lignin extracted from fig stems was characterized regarding to its structural feature, quantification of its functional groups, molecular weight, and evaluation of its thermal properties. Purity and molecular weight distribution of the studied lignin indicated that isolated lignin contained a low amount of sugar (c.a. 19%) and had a high weight-average molecular weight (10… More >

  • Open Access

    ARTICLE

    Total Phenols, Flavonoids and Antioxidant Activity in Annona muricata and Annona purpurea Callus Culture

    M. Y. Ovando-Domínguez1, M. C. Luján-Hidalgo1, D. González-Mendoza2, A. A. Vargas-Díaz3, N. Ruiz-Lau1,4, F. A. Gutiérrez-Miceli1, C. A. Lecona-Guzmán1,*

    Phyton-International Journal of Experimental Botany, Vol.88, No.2, pp. 139-147, 2019, DOI:10.32604/phyton.2019.06546

    Abstract Callus cultures of Annona muricata and Annona purpurea were induced in Murashige and Skoog (MS) medium supplemented with different concentrations of 1-naphthylacetic acid (NAA), 6-benzyladenine (BA) and 2,4-dichlorophenoxyacetic acid (2,4-D) utilized hypocotyls with explant. The highest percentage of callus formation was the treatment supplemented with 3 mg L-1 NAA for A. muricata (100%) while for A. purpurea in lower percentage (75%). BA stimulated the formation of shoots in all the evaluated concentrations, being the concentration of 2 mg L-1 the one that induced the greater formation of shoots for A. muricata (23 shoots/explant) and A. purpurea (28 shoots/explant). The content… More >

  • Open Access

    ARTICLE

    Antioxidant Migration Studies in Chitosan Films Incorporated with Plant Extracts

    Victor Gomes Lauriano Souza1, Patrícia Freitas Rodrigues2, Maria Paula Duarte1, Ana Luísa Fernando1*

    Journal of Renewable Materials, Vol.6, No.5, pp. 548-558, 2018, DOI:10.7569/JRM.2018.634104

    Abstract The aim of this work was to develop an active biopolymer based on chitosan by incorporating natural antioxidants. Five essential oils (ginger, rosemary, sage, tea tree and thyme) and six hydro-alcoholic extracts (from ginger, green and black tea, kenaf leaves, rosemary and sage plants) were tested. Migration assays were carried out to evaluate the films' activity, and total phenolic content and antioxidant activity were monitored in the simulant during storage. Interaction between natural compounds and polymeric matrix was evaluated by FTIR spectroscopy. The diffusion of the phenolic compounds was not detected in the films incorporated with hydro-alcoholic extracts (HAEs), indicating… More >

  • Open Access

    ARTICLE

    Hydroxytyrosol as Active Ingredient in Poly(vinyl alcohol) Films for Food Packaging Applications

    Elena Fortunati1*, Francesca Luzi1, Chiara Fanali2, Laura Dugo2, Maria Giovanna Belluomo2, Luigi Torre1, José Maria Kenny1, Luca Santi3, Roberta Bernini3

    Journal of Renewable Materials, Vol.5, No.2, pp. 81-95, 2017, DOI:10.7569/JRM.2016.634132

    Abstract Hydroxytyrosol (HTyr), a biophenol found in extra-virgin olive oil or olive oil by-products, well known for its strong antioxidant activity, was used as active ingredient for poly(vinyl alcohol) (PVA) matrix to develop film formulations by solvent casting process. The effect of HTyr on the morphological, thermal stability, optical, mechanical and release properties of PVA were investigated, while water absorption capacity, migration with food stimulants, water vapor permeability and antioxidant properties were tested taking into account the final application as food packaging systems. Morphological investigations evidenced homogeneity of all PVA/HTyr films, while the presence of HTyr clearly accounted for an increase… More >

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