Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (28)
  • Open Access

    ARTICLE

    Anti-inflammatory and antioxidant potential capacities of AD-MSCs and BM-MSCs in suppressing pancreatic β-cells auto-immunity and apoptosis in rats with T1DM induced model

    SHADY G. EL-SAWAH1,*, FAYEZ ALTHOBAITI2, HANAN M. RASHWAN1, ADIL ALDHAHRANI3, MARWA A. ABDEL-DAYEM4, EMAN FAYAD2, REHAB M. AMEN5, EL SHAIMAA SHABANA6, EHAB I. EL-HALLOUS7

    BIOCELL, Vol.46, No.3, pp. 745-757, 2022, DOI:10.32604/biocell.2022.017853

    Abstract Since Type 1 diabetes (T1DM) occurs when β-cells mass is reduced to less than 20% of the normal level due to autoimmune destruction of cells resulting in the inability to secrete insulin, preservation or replenishment of the functional β-cells mass has become a major therapeutic focus for this diabetic type treatment. Thus, this 4-week work plan was designed to determine which mesenchymal stem cells (MSCs) type is more appropriate to alleviate pancreatic hazards resulting from diabetes induction; via tracking a comparative study between MSCs derived from adipose tissue (AD-MSCs) and from bone marrow (BM-MSCs) in… More >

  • Open Access

    ARTICLE

    Oxidative effects of glyphosate on the lipophobic intracellular environment in the microalgae Chlorella vulgaris

    JUAN MANUEL OSTERA1,2, SUSANA PUNTARULO1,2, GABRIELA MALANGA1,2,*

    BIOCELL, Vol.46, No.3, pp. 795-802, 2022, DOI:10.32604/biocell.2022.017294

    Abstract

    The studied hypothesis is that the herbicide glyphosate (GLY) can affect the oxidative balance in the hydrophobic intracellular medium in non-target Chlorella vulgaris cells. Analytical GLY and RoundUp (RUP) supplementation, affected the growth profile. A significant 42% decrease in the cellular biomass in stationary (St) phase was observed in cultures supplemented with either 5 µM of GLY or RUP, as compared to control cultures. The treatment with 0.3 µM of GLY generated non-significant effects on the oxidation rate of 2’, 7’ dichlorofluorescein diacetate (DCFH-DA), neither in exponential (Exp) nor in St phase of development, as compared to

    More >

  • Open Access

    ARTICLE

    Curcumin gum Arabic nanoparticles demonstrate potent antioxidant and cytotoxic properties in human cancer cells

    ABDELKADER HASSANI1,2,3, SITI ASLINA HUSSAIN2, MOTHANNA SADIQ AL-QUBAISI4, MOHAMED LAKHDER BELFAR3, HAKIM BELKHALFA5, HAMID HAMMAD ENEZEI6, HAMID ZENTOU2, WISAM NABEEL IBRAHIM7,8,*, ABD ALMONEM DOOLAANEA1,*

    BIOCELL, Vol.46, No.3, pp. 677-687, 2022, DOI:10.32604/biocell.2022.016848

    Abstract The main purpose of the study was to enhance the stability and therapeutic effects of Curcumin (Cur) through nanoformulation with gum Arabic (GA) as a coating agent through an efficient synthetic approach. The antioxidant properties of the developed nanoparticles (Cur/GANPs) were assessed through several in vitro assays, such as β-carotene bleaching activity, DPPH, and nitric oxide scavenging activities in addition to evaluating its inhibitory activity on angiotensin-converting enzyme (ACE). The cytotoxicity of Cur/GANPs was evaluated in vitro using different types of human cancer cells including breast cancer (MCF7, MDA-MB231), liver cancer (HepG2), and colon cancer (HT29) cells. More >

  • Open Access

    ARTICLE

    Effect of strawberry vein banding virus and strawberry mottle virus co-infection on the growth and development of strawberry

    LINGJIAO FAN1, DAN SONG1, YINGWEI KHOO2, MENGMENG WU1, TENGFEI XU1, XIAOLI ZHAO1, HONGQING WANG1

    BIOCELL, Vol.46, No.1, pp. 263-273, 2022, DOI:10.32604/biocell.2022.016306

    Abstract

    Strawberry mottle virus (SMoV) and strawberry vein banding virus (SVBV) cause diseases on strawberry plants, but the effect of coinfection of SMoV and SVBV on the growth, development, and defense system of strawberry (Fragaria × ananassa Duchesne) remains unknown. We investigated the effect of SMoV and SVBV co-infection on strawberry cultivar ‘Benihope’. The results showed that stem diameter, leaf size, leaf number, relative chlorophyll content, total chlorophyll content, photosynthetic parameters, and stomatal aperture of SMoV and SVBV co-infected strawberry (VIS) plants were in a weaker level than uninfected control plants, indicating that viruses inhibited the growth and

    More >

  • Open Access

    ARTICLE

    Investigation of the antioxidant defensive role of both AD-MSCs and BM-MSCs in modulating the alteration in the oxidative stress status in various STZ-diabetic rats’ tissues

    SHADY G. EL-SAWAH1,*, FAYEZ ALTHOBAITI2, ADIL ALDHAHRANI3, EMAN FAYAD2, MARWA A. ABDEL-DAYEM4, REHAB M. AMEN5, EL SHAIMAA SHABANA6, EHAB I. EL-HALLOUS7, HANAN M. RASHWAN1

    BIOCELL, Vol.45, No.6, pp. 1561-1568, 2021, DOI:10.32604/biocell.2021.016869

    Abstract Diabetes mellitus (DM) could negatively affect patients’ health via inducing a lot of serious functional hazards in many tissues’ cells at molecular levels. Recently, many scientists had proposed stem cell therapy being an appropriate alternative treatment protocol for numerous health threatening issues including diabetes. Therefore, the current study was designed to investigate the antioxidant potentiality of two MSCs types in alleviating tissues’ oxidative stress dramatic elevation resulting as a consequence of Type 1 DM induction. In our 4 weeks study, animals were divided into four groups: control group, STZ-diabetic group (D), D+AD-MSCs group and D+BM-MSCs… More >

  • Open Access

    ARTICLE

    Application of ferrous sulfate alleviates negative impact of cadmium in rice (Oryza sativa L.)

    JAVARIA AFZAL1,2,#, XIUKANG WANG3,*, MUHAMMAD HAMZAH SALEEM4,#, XUECHENG SUN1, SHAHID HUSSAIN5, IMRAN KHAN6, MUHAMMAD SHOAIB RANA1, SHAKEEL AHMED7, SAMRAH AFZAL AWAN6, SAJID FIAZ8, OMAR AZIZ9, KASHIF ALI KUBAR10, SHAFAQAT ALI11,12, CHENGXIAO HU1,*

    BIOCELL, Vol.45, No.6, pp. 1631-1649, 2021, DOI:10.32604/biocell.2021.014934

    Abstract Soil contamination with toxic heavy metals [such as cadmium (Cd)] is becoming a serious global problem due to rapid development of social economy. Iron (Fe), being an important element, has been found effective in enhancing plant tolerance against biotic and abiotic stresses. The present study investigated the extent to which different levels of Ferrous sulphate (FeSO4) modulated the Cd tolerance of rice (Oryza sativa L.), when maintained in artificially Cd spiked regimes. A pot experiment was conducted under controlled conditions for 146 days, by using natural soil, mixed with different levels of CdCl2 [0 (no Cd), 0.5… More >

  • Open Access

    REVIEW

    Morpho-Physiological, Biochemical and Molecular Adaptation of Millets to Abiotic Stresses: A Review

    Seerat Saleem1, Naveed Ul Mushtaq1, Wasifa Hafiz Shah1, Aadil Rasool1, Khalid Rehman Hakeem2,*, Reiaz Ul Rehman1,*

    Phyton-International Journal of Experimental Botany, Vol.90, No.5, pp. 1363-1385, 2021, DOI:10.32604/phyton.2021.014826

    Abstract Abiotic stresses such as drought, heat, cold, nutrient deficiency, excess salt and hazardous metals can hamper plantgrowth and development. Intensive agriculture of only a few major staple food crops that are sensitive and intolerant to environmental stresses has led to an agrarian crisis. On the other hand, nutritionally rich, gluten free and stress tolerant plants like millets are neglected and underutilized. Millets sustain about one-third of the world’s population and show exceptional tolerance to various abiotic and biotic stresses. Millets are C4 plants that are adapted to marginal and dry lands of arid and semi-arid… More >

  • Open Access

    ARTICLE

    Overexpression of rice F-box phloem protein gene OsPP12-A13 confers salinity tolerance in Arabidopsis

    CHUNKUN FAN, YONGPENG ZHANG, CHUNBAO YANG, YAWEI TANG, JI QU, BU JIE, DEJI QUZHEN, LIYUN GAO*

    BIOCELL, Vol.45, No.4, pp. 1121-1135, 2021, DOI:10.32604/biocell.2021.014336

    Abstract Salinity is a serious challenge for agriculture production by limiting the arable land. Rice is a major staple food crop but very sensitive to salt stress. In this study, we used Arabidopsis for the functional characterization of a rice F-box gene LOC_Os04g48270 (OsPP12-A13) under salinity stress. OsPP12-A13 is a nuclear-localized protein that is strongly upregulated under salinity stress in rice and showed the highest expression in the stem, followed by roots and leaves. Two types of transgenic lines for OsPP12-A13 were generated, including constitutive tissue over-expression using the CaMV35S promoter and phloem specific over-expression using the pSUC2 promoter.… More >

  • Open Access

    ARTICLE

    Analysis of Antioxidant Potential of Trigonella foenum-graecum (L.) Extract Against Tumorigenesis

    Shivangi Goyal, Sreemoyee Chatterjee, Nidhi Gupta*

    Oncologie, Vol.23, No.1, pp. 89-104, 2021, DOI:10.32604/Oncologie.2021.015234

    Abstract Background: Trigonella foenum-graecum Linn. has been extensively used for medicinal purposes. The current study deals with in vitro and in vivo correlation of free radical quenching activity and anticancer potential of seed extracts of Trigonella. Materials and methods: Antioxidant activity was evaluated against DPPH, NO and ABTS via in vitro radical scavenging assay. Cytotoxicity effect of Trigonella seed extract was studied in human embryonic kidney HEK 293 cell line by alamar blue assay. In vivo antioxidant activity in Swiss albino mice model was assessed by studying endogenous antioxidant enzymes such as GSH, GPx, SOD and LPO. Antitumor effect was observed by studying parameters… More >

  • Open Access

    ARTICLE

    Effects of Exogenous Manganese (Mn) on Mineral Elements, Polyamines and Antioxidants in Apple Rootstock Malus robusta Rehd.

    Dazhuang Qi1,2,4,#, Meixia Liang1,2,4,#, Fudong Jiang3, Jianzhao Li1,2,4, Xuqiang Qiao1,2,4,*, Hongxia Zhang1,2,4,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.4, pp. 943-955, 2020, DOI:10.32604/phyton.2020.013801

    Abstract Manganese (Mn) is one of the essential microelements in all organisms. However, high level of Mn is deleterious to plants. In this study, the effects of exogenous manganese application on mineral element, polyamine (PA) and antioxidant accumulation, as well as polyamine metabolic and antioxidant enzyme activities, were investigated in Malus robusta Rehd., a widely grown apple rootstock. High level of Mn treatments decreased endogenous Mg, Na, K and Ca contents, but increased Zn content, in a Mn-concentration-dependent manner. Polyamine metabolic assays revealed that, except the content of perchloric acid insoluble bound (PIS-bound) spermine, which increased significantly,… More >

Displaying 11-20 on page 2 of 28. Per Page