Virna Margarita Martín Giménez¹, SebastiáN GarcíA MenéNdez^2,3, Luiz Gustavo A. Chuffa⁴, Vinicius Augusto SimãO⁴, Russel J. Reiter⁵, Ramaswamy Sharma⁶, Walter Balduini⁷, Carla Gentile⁸, Walter Manucha^2,3,*

BIOCELL, Vol.49, No.12, pp. 2245-2282, 2025, DOI:10.32604/biocell.2025.071830 - 24 December 2025

Abstract Neurodegenerative diseases (NDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) are characterized by progressive neuronal loss, which is closely linked to mitochondrial dysfunction. These pathologies involve a complex interplay of genetics, protein misfolding, and cellular stress, culminating in impaired energy metabolism, an increase in reactive oxygen species (ROS), and defective mitochondrial quality control. The accumulation of damaged mitochondria and dysregulation of pathways such as the Integrated Stress Response (ISR) are central to the pathogenesis of these conditions. This review explores the critical relationship between mitochondrial stress… More >

Kezheng Gao¹, Shuaifei Li¹, Qingyuan Niu², Xiaojing Zhang^2,*

Journal of Renewable Materials, Vol.13, No.12, pp. 2309-2353, 2025, DOI:10.32604/jrm.2025.02025-0108 - 23 December 2025

Abstract The current global shortage of oil resources and the pollution problems caused by traditional barrier materials urgently require the search for new substitutes. Biodegradable bio-based barrier materials possess the characteristics of being renewable, environmentally friendly, and having excellent barrier properties. They have become an important choice in fields such as food packaging, agricultural film covering, and medical protection. This review systematically analyzes the design and research of this type of material, classifying biobased and biodegradable barrier materials based on the sources of raw materials and synthesis pathways. It also provides a detailed introduction to the More >

Su Li¹, Nooreen Noordin², Dan Wang^3,*

International Journal of Mental Health Promotion, Vol.27, No.11, pp. 1797-1812, 2025, DOI:10.32604/ijmhp.2025.072301 - 28 November 2025

Abstract Background: Communication barriers are a critical yet underexplored determinant of psychological well-being in oncology care, particularly among rural Chinese patients treated in urban hospitals. This study examined how Mandarin proficiency influences emotional distress and identified implications for mental health promotion. Methods: A sequential mixed-methods design was adopted. Quantitative data were collected from 180 rural cancer patients using the Putonghua Proficiency Test (PSC), the Hospital Anxiety and Depression Scale (HADS), and the Distress Thermometer (DT). Multiple linear regressions estimated covariate-adjusted associations between Mandarin proficiency and distress outcomes, controlling for demographic and clinical factors. Semi-structured interviews with 20… More >

Beth Steinberg^1,*, Yulia Mulugeta¹, Catherine Quatman-Yates², Maeghan Williams², Anvitha Gogineni¹, Maryanna Klatt¹

International Journal of Mental Health Promotion, Vol.27, No.9, pp. 1237-1264, 2025, DOI:10.32604/ijmhp.2025.067232 - 30 September 2025

Abstract Background: Community-based first responders face high levels of workplace stressors that can profoundly impact their physical and mental health. Mindfulness-based interventions have shown promise in decreasing stress and increasing psychological resilience; however, implementation is difficult due to unpredictability of the job, department culture, and generational preferences. The objective of this qualitative study was to identify and enhance understanding of the specific needs and potential barriers and facilitators for the implementation of mindfulness-based programming for community-based first responders. Methods: A phenomenological qualitative study design was used to gain insights into the lived experiences of first responders… More >

Fan Sun^1,2, Yiwen Chen^2,3, Dingjun Li³, Rong Xu², Peng Jiang², Tiejun Wang², Lei Yang^1,2,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.012370

Abstract The capacity to maintain operational temperatures within safe thresholds is paramount for the longevity of thermal barrier coating systems (TBCs). Nonetheless, TBC spallation during service can lead to localized over temperature, which may result in catastrophic failure. In this study, we examine the phenomenon of over temperature in locally spalled TBCs through a combination of numerical simulations and experimental investigations. We perform numerical calculations to determine the temperature distributions in locally spalled TBCs with varying spallation depths and diameters, and we analyze the correlation between the maximum temperature within the spalled regions and the dimensions… More >

Myoung Cheol Shin¹, Tae-Kyeong Lee², Dae Won Kim³, Joon Ha Park⁴, Moo-Ho Won¹, Choong-Hyun Lee^5,*, Ji Hyeon Ahn^6,*

BIOCELL, Vol.49, No.6, pp. 1071-1083, 2025, DOI:10.32604/biocell.2025.065506 - 24 June 2025

Abstract Background: Astrocyte endfeet (AEF) serves as a key element of the blood-brain barrier and is important for the survival and maintenance of neuronal function. However, the immunohistochemical and ultrastructural changes of AEF in the CA1 and CA3 areas of the hippocampus over time following cerebral ischemia-reperfusion (IR) injury have not been well elucidated. Objectives: We investigated chronological changes in AEF in the gerbil hippocampal CA1 area from 3 h to 10 days following transient forebrain ischemia (TFI), and examined their association with neuronal death and tissue repair following IR injury. Changes in the CA3 area… More >

Natalia Lehman, Agnieszka Bojarska-Junak, Michał Zarobkiewicz^*

BIOCELL, Vol.49, No.6, pp. 1085-1099, 2025, DOI:10.32604/biocell.2025.063960 - 24 June 2025

Abstract Introduction: Butyrophilins (BTNs) belong to the immunoglobulin superfamily; they play crucial roles in immune regulation, especially in γδ T cell activation. While their expression has been studied in solid tumours, their involvement in hematologic malignancies remains poorly understood. Objectives: We hypothesised that BTNs are dysregulated in chronic lymphocytic leukaemia (CLL), contributing to γδ T cell dysfunction and potentially influencing disease progression. Methods: In this study, we analyzed publicly available microarray and RNA-seq datasets to investigate the expression patterns of BTN genes in CLL. Results: Our findings reveal significant dysregulation of BTN gene expression in CLL, with BTN2A1, BTN3A1, BTN3A2,… More >

Noverra Mardhatillah Nizardo^1,*, Alifah Nurul Saffanah¹, Annisa Fitri Salsabila¹, Amanda Aurellia Putri¹, Aniek Sri Handayani², Azizah Intan Pangesty³, Mochamad Chalid³

Journal of Renewable Materials, Vol.13, No.6, pp. 1209-1227, 2025, DOI:10.32604/jrm.2025.02024-0068 - 23 June 2025

Abstract Food packaging is becoming popular as the consumption of ready-to-eat food products rises. Easy-to-use, non-biodegradable plastic packaging is commonly used in food packaging, contributing to the deteriorating environmental situation. This issue increases the concern for the environment and encourages the usage of alternative materials. Cellulose nanofibrils (CNF) are abundant and biodegradable, which makes them ideal candidates to replace plastic coatings. The ability to form H-bonds between the hydroxyl groups makes coated paper with CNF have good strength, but poor barrier properties. The barrier properties can be improved by grafting DMAEMA or HEMA onto CNF (CNF-g-PDMAEMA… More > Graphic Abstract

Sajjad Tariq A. Shafi, Mohammed K. Al-Saadi, Ameer Abed Jaddoa^*

Frontiers in Heat and Mass Transfer, Vol.23, No.2, pp. 703-719, 2025, DOI:10.32604/fhmt.2025.063118 - 25 April 2025

Abstract To improve the heat transfer rate and thermal performance of the solar air heater due to low efficiency, new techniques, such as artificial roughness, barriers, and obstacles, should be used to increase the heat exchange between the fluid and the absorber. In this research, perforated V-shaped blockages with new geometric shapes, which are circular, hexagonal, square, rectangular, and triangular, were used. They were fixed on the absorber plate inside the channel with dimensions of 1.5 m × 0.5 m × 0.05 m, which increased the exit temperature of the air passing through the channel. The… More > Graphic Abstract

Haydar Abdulameer Marhoon^1,2,*, Rafid Sagban^3,4, Atheer Y. Oudah^1,5, Saadaldeen Rashid Ahmed^6,7

CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4181-4218, 2025, DOI:10.32604/cmc.2025.058822 - 06 March 2025

Abstract In order to address the critical security challenges inherent to Wireless Sensor Networks (WSNs), this paper presents a groundbreaking barrier-based machine learning technique. Vital applications like military operations, healthcare monitoring, and environmental surveillance increasingly deploy WSNs, recognizing the critical importance of effective intrusion detection in protecting sensitive data and maintaining operational integrity. The proposed method innovatively partitions the network into logical segments or virtual barriers, allowing for targeted monitoring and data collection that aligns with specific traffic patterns. This approach not only improves the diversit. There are more types of data in the training set,… More >