Xiangmei Ye^1,2,3, Baoyi Yang⁴, Xin Zhang⁵, Luyuan Yang¹, Likun Zhang⁵, Qin Ren¹, Xiaobing Li¹, Leiguang Feng¹, Lanlan Wei^3,6,7,*, Peng Song¹, Yuqing Ye⁸, Xin Lian⁹, Yujuan Gao⁹, Haidi Tang¹, Zhiyu Liu¹

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068814 - 30 December 2025

Abstract Objectives: Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia and Philadelphia-like B-cell acute lymphoblastic leukemia (Ph+/Ph-like ALL) constitute the majority of relapsed/refractory B-ALL (R/R B-ALL) cases, highlighting an urgent need to discover new therapeutic targets. This study aims to elucidate the mechanisms underlying poor prognosis in Ph+/Ph-like ALL through transcriptome sequencing and functional cytological assays, with the goal of informing new clinical treatment strategies. Results: Transcriptomic analysis of Ph+/Ph-like ALL patients revealed that low expression of P2X Purinoceptor 1 (P2RX1) was associated with unfavorable outcomes. Specifically, patients with poor prognosis and low P2RX1 expression exhibited downregulation of… More >

Jie Jin¹, Tianci Wang¹, Yaning Wang¹, Jingqi Yao², Jinxiu Song^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3611-3632, 2025, DOI:10.32604/phyton.2025.070680 - 01 December 2025

Abstract In plant factory with artificial lighting, precise regulation of environmental and nutritional factors is essential to optimize both growth and quality of leafy vegetables. This study systematically evaluated the combined effects of light intensity (150, 200, 250 μmol/(m²·s)) and calcium supply in the nutrient solution (0.5, 1.0, 1.5 mmol/L) on lettuce morphology, photosynthesis, quality indices, and tipburn incidence. Elevating light from 150 to 200 μmol/(m²·s) significantly enhanced leaf number, area, photosynthetic rate, biomass, and foliar calcium. These gains plateaued at 250 μmol/(m²·s), where tipburn incidence surged to 76.5%. Photosynthetic pigments progressively rose with light intensity. Calcium supply… More >

Sara Y. Aldeghaither, Jawaher Alsughayyir, Sabiha Fatima, Mohammad A. Alfhili^*

BIOCELL, Vol.49, No.11, pp. 2167-2180, 2025, DOI:10.32604/biocell.2025.071827 - 24 November 2025

Abstract Objectives: Targeting epigenetic modifications in anticancer therapy is a promising approach to overcoming cancer cell chemoresistance. The histone deacetylase/DNA methyltransferase inhibitor, parthenolide (PTL), has antitumor activity, but contrasting findings exist on its effect in normal cells. This study aims to examine the non-genomic toxic mechanisms of PTL in human erythrocytes. Methods: Cell death as stimulated by 20–200 μM of PTL for 24 h at 37°C was assessed using fluorescence-assorted cell sorting and spectrophotometric assays. Canonical markers of cell death, including membrane scrambling, oxidative stress, and Ca²⁺ mobilization, were captured by annexin V-fluorescein isothiocyanate, 2^′,7^′-dichlorodihydrofluorescein diacetate, and… More >

Abdulbari Bener^1,2,*, Ünsal Veli Üstündağ³, Emir Barışık⁴, Cem Cahit Barışık⁵

Canadian Journal of Urology, Vol.32, No.5, pp. 401-409, 2025, DOI:10.32604/cju.2025.067184 - 30 October 2025

Abstract Objectives: The evidence remains insufficient and controversial for evaluating modifiable parameters—such as vitamin D, calcium, ferritin, and uric acid—as preclinical biomarkers to contribute to the prevention and early diagnosis of prostate cancer, a disease with a prevalence of up to 10%–20% in men over 50 and strongly associated with environmental factors including diet (high in fat and red meat), obesity, physical inactivity, and carcinogen exposure. This study aims to investigate the potential biomarker role of vitamin D, calcium, ferritin, and uric acids in reducing the risk of prostate cancer (PCa). Methods: The case-control design was… More >

Madihan Yusof^1,2,3,*, Muhamad Saiful Sulaiman^1,3, Ros Syazmini Mohd Ghani^1,3,4, Sofiyah Mohd Razali^1,5

Journal of Renewable Materials, Vol.13, No.10, pp. 2059-2075, 2025, DOI:10.32604/jrm.2025.02025-0101 - 22 October 2025

Abstract This study investigates the development of an oil palm trunk (OPT) high-performance flame-retardant composite derived from an inexpensive and sustainable biomass source, processed using sodium chloride (NaCl) as a low-cost flame retardant, polyvinyl alcohol (PVA) as an adhesive, and calcium carbonate (CaCO₃) as an additive. The work aims to address the inherent flammability of OPT and to enhance its mechanical performance, dimensional stability, and fire resistance in an environmentally friendly and cost-effective manner. Results indicate that a 10% NaCl treatment optimally improves the performance of the composite, increasing bending strength (MOR) from 5.95 to 12.61 MPa… More > Graphic Abstract

Shiyang Zhang^1,#, Jingchen Li^1,#, Qianxu Jin², Siyu Zhu¹, Hongshan Yan², Yizheng Wang³, Zihan Song¹, Liqiang Liu^1,*

Oncology Research, Vol.33, No.10, pp. 2961-2979, 2025, DOI:10.32604/or.2025.064300 - 26 September 2025

Abstract Background: Glioma is the most common tumor of the central nervous system with a poor prognosis. This study aims to explore the role of calcium/calmodulin-dependent protein kinase IIβ (CAMK2B) in regulating the malignant progression of glioma cells, as well as the molecular mechanisms underlying these malignant behaviors. Methods: The correlation between CAMK2B expression in gliomas and patient prognosis was analyzed using immunohistochemistry, quantitative reverse transcription polymerase chain reaction (qRT-PCR), and western blot. Furthermore, the study explored the role of CAMK2B in glioma cell proliferation, invasion, and migration using cell counting kit-8 (CCK-8), 5-Ethynyl-2^′-deoxyuridine (EdU), wound healing,… More >

Shiyang Li^1,#, Jia Song^1,#, Bingxuan Fan¹, Yunshu Tang², Yamin Xing¹, Yuqi Gao¹, Nianwei Qiu^1,*, Hongxia Zhang^1,3,*

Phyton-International Journal of Experimental Botany, Vol.94, No.6, pp. 1811-1826, 2025, DOI:10.32604/phyton.2025.065751 - 27 June 2025

Abstract Strontium has similar chemical properties to calcium and has recently been recognized as a non-essential beneficial element for plants. In order to compare the effects of strontium and calcium on improving salt tolerance of Chinese cabbage during the germination stage, 2, 4, and 8 mmol/L of SrCl₂, CaCl₂ or an equimolar mixture of both were added separately to a 150 mmol/L NaCl solution. The results showed that Ca-Sr addition significantly increased seed viability, seed vigor, seed germination rate and seed germination uniformity of Chinese cabbage compared with the salt-control group. The differences in germination percentage (GP)… More >

Gwang Mok Kim^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.012583

Abstract This study summarized a part of the research conducted by Kim et al. [1]. The utilization of low-lime calcium silicate cement presents a promising avenue for reducing CO2 emissions in construction fields. Ordinary Portland cement pastes with the type of calcium silicate cement powder were fabricated and solidified under carbonation curing conditions. The physicochemical characteristics of the pastes were examined via variable tests including initial setting and flow characteristics, compressive strength and so on. Limestone and silica fume were employed for the synthesis of the calcium silicate cement used here. The content of calcium silicate More >

Jiaming Zhan^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.011189

Abstract Calcium fluoride (CaF₂) exhibits excellent optical properties, making it a promising candidate for preparing optical components. The actual applications underscore the importance of enhancing the ductile machining of such a difficult-to-machine material. This study starts by investigating the influence of thermal gradient fields on the mechanical behaviors of CaF₂ single crystal experimentally and theoretically, revealing the potential deformation mechanisms under various thermal additions. On this basis, a novel laser-assisted machining (LAM) scheme was proposed to enhance the deformability and machinability of CaF₂ single crystal by tailoring local thermal fields. The laser heating spot within the work material… More >

Jinshuo Wang, Lida Xing, Fulong Zhang, Chuanfu Liu^*

Journal of Renewable Materials, Vol.12, No.1, pp. 89-102, 2024, DOI:10.32604/jrm.2023.029057 - 23 January 2024

Abstract Wood-based functional materials have developed rapidly. But the flammability significantly limits its further application. To improve the flame retardancy, the balsa wood was delignified by NaClO₂ solution to create a cellulose scaffold, and then alternately immersed in CaCl₂ ethanol solution and NaHCO₃ aqueous solution under vacuum. The high porosity and wettability resulting from delignification benefited the following mineralization process, changing the thermal properties of balsa wood significantly. The organic-inorganic wood composite showed abundant CaCO₃ spherical particles under scanning electron microscopy. The peak of the heat release rate of delignified balsa-CaCO₃ was reduced by 33% compared to the native More > Graphic Abstract