Renaud Mabire-Yon^1,*, Arnaud Siméone¹, Thibaud Marmorat², Anne-Sophie Petit¹, Mathilde Perray¹, Costanza Puppo¹, Charlotte Bauquier¹, Claire Della Vecchia¹, Hervé Picard³, Marie Préau¹

Psycho-Oncologie, Vol.17, No.4, pp. 245-256, 2023, DOI:10.32604/po.2023.042296 - 28 December 2023

Abstract Objectifs : Cette étude visait à déterminer si les personnes atteintes d’un cancer (PAC) présentaient un profil unique de perception du risque COVID-19 et à identifier les facteurs psychosociaux caractérisant les PAC qui n’appartenaient pas au profil majoritaire de perception du risque. Procédure : Une étude transversale par auto-questionnaire en ligne a été menée en France du 25 avril au 7 mai 2020, avec un échantillon (n = 748) comprenant des PAC, des personnes ne recevant pas de traitement contre le cancer et des personnes n’ayant pas d’antécédents de cancer. Des profils latents de perception du risque… More >

FATEMEH HEIDARI^1,2, REIHANEH SEYEDEBRAHIMI^1,2, PIAO YANG³, MOHSEN ESLAMI FARSANI^1,2, SHIMA ABABZADEH^2,4, NASER KALHOR⁵, HAMED MANOOCHEHRI⁶, MOHSEN SHEYKHHASAN^7,*, MARYAM AZIMZADEH^8,9,*

BIOCELL, Vol.47, No.12, pp. 2597-2608, 2023, DOI:10.32604/biocell.2023.043351 - 27 December 2023

Abstract Exosomes are small vesicles that carry molecules from one cell to another. They have many features that make them interesting for research, such as their stability, low immunogenicity, size of the nanoscale, toxicity, and selective delivery. Exosomes can also interact with viruses in diverse ways. Emerging research highlights the significant role of exosomes in viral infections, particularly in the context of diseases like COVID-19, HIV, HBV and HCV. Understanding the intricate interplay between exosomes and the human immune system holds great promise for the development of effective antiviral therapies. An important aspect is gaining clarity More >

Qi Li, Jinsheng Hu^*, Peng Wan

International Journal of Mental Health Promotion, Vol.25, No.11, pp. 1173-1186, 2023, DOI:10.32604/ijmhp.2023.030343 - 08 December 2023

Abstract

Given the ongoing character of COVID-19, higher-education students encountered multifaceted pressures brought about by the pandemic and had to overcome many difficulties during this period. Accordingly, it is imperative to identify the factors that may have protective effects on the social functioning and mental status of college students in the aftermath of COVID-19. This cross-sectional study sought to ascertain the internal mechanism of positive coping (PC) styles affecting post-traumatic growth (PTG) and considered the mediating roles of cognitive reappraisal (CR), psychological resilience (PR), and deliberate rumination (DR), which are essential for understanding how and to

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PRIYADHARSHINI THANJAVUR SRIRAMAMOORTHI^1,2, GAYATHRI GOPAL^1,2, SHIBI MURALIDAR^1,2, SAI RAMANAN ESWARAN^1,2, DANUSH NARAYAN PANNEERSELVAM^1,2, BHUVANESWARAN MEIYANATHAN^1,2, SRICHANDRASEKAR THUTHIKKADU INDHUPRAKASH^1,2, SENTHIL VISAGA AMBI^1,2,*

BIOCELL, Vol.47, No.11, pp. 2335-2350, 2023, DOI:10.32604/biocell.2023.029379 - 27 November 2023

Abstract The novel coronavirus pneumonia (COVID-19) is spreading worldwide and threatening people greatly. The routes by which SARS-CoV-2 causes lung injury have grown to be a major concern in the scientific community since patients with new Coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV-2) have a high likelihood of developing acute respiratory distress syndrome (ARDS) in severe cases. The mortality rate of COVID-19 has increased over the period due to rapid spread, and it becomes crucial to understand the disease epidemiology, pathogenic mechanisms, and suitable treatment strategies. ARDS is a respiratory disorder and is one of the… More > Graphic Abstract

VIBHAV VARSHNEY^1,*, PRASHANT SINGH KUSHWAH², NEETU AGRAWAL¹, AHSAS GOYAL^1,*, GOVIND SINGH²

BIOCELL, Vol.47, No.10, pp. 2141-2149, 2023, DOI:10.32604/biocell.2023.030853 - 08 November 2023

Abstract The persistent global pandemic, COVID-19, stems from the pathogenic influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), yielding an unprecedented worldwide crisis. With reference to a WHO report, the count of COVID-19 cases had exceeded 754 million by February 03, 2023. Intriguingly, emerging research has spotlighted the intricate interplay of gut microbiota and mitochondrial entities, acting as potent immunomodulatory factors at the cellular and molecular levels. This interconnection operates through a series of dynamic mechanisms. SARS-CoV-2 infection perturbs the delicate equilibrium of gut microbiota, leading to dysbiosis—a signature biomarker. This imbalance is intrinsically linked More >

AMGAD M. RABIE^*

BIOCELL, Vol.47, No.10, pp. 2133-2139, 2023, DOI:10.32604/biocell.2023.030057 - 08 November 2023

Abstract Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease still represents a major concern to the relevant scientific and medical communities. The primary concern of drug scientists, virologists, and other concerned specialists in this respect is to find ready-to-use suitable and potent anticoronaviral therapies that are broadly effective against the different species/strains of the coronaviruses in general, not only against the current and previous coronaviruses (e.g., the recently-appeared severe acute respiratory syndrome coronavirus 2 “SARS-CoV-2”), i.e., effective antiviral agents for treatment and/or prophylaxis of any coronaviral infections, including More > Graphic Abstract

Fadhil Mukhlif^1,*, Norafida Ithnin¹, Roobaea Alroobaea², Sultan Algarni³, Wael Y. Alghamdi², Ibrahim Hashem⁴

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 583-599, 2023, DOI:10.32604/cmc.2023.038757 - 31 October 2023

Abstract The World Health Organization (WHO) refers to the 2019 new coronavirus epidemic as COVID-19, and it has caused an unprecedented global crisis for several nations. Nearly every country around the globe is now very concerned about the effects of the COVID-19 outbreaks, which were previously only experienced by Chinese residents. Most of these nations are now under a partial or complete state of lockdown due to the lack of resources needed to combat the COVID-19 epidemic and the concern about overstretched healthcare systems. Every time the pandemic surprises them by providing new values for various… More >

Jingyao Liu^1,2, Qinghe Feng⁴, Jiashi Zhao^2,3, Yu Miao^2,3, Wei He², Weili Shi^2,3, Zhengang Jiang^2,3,*

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 2649-2665, 2023, DOI:10.32604/cmc.2023.038891 - 08 October 2023

Abstract The coronavirus disease 2019 (COVID-19) has severely disrupted both human life and the health care system. Timely diagnosis and treatment have become increasingly important; however, the distribution and size of lesions vary widely among individuals, making it challenging to accurately diagnose the disease. This study proposed a deep-learning disease diagnosis model based on weakly supervised learning and clustering visualization (W_CVNet) that fused classification with segmentation. First, the data were preprocessed. An optimizable weakly supervised segmentation preprocessing method (O-WSSPM) was used to remove redundant data and solve the category imbalance problem. Second, a deep-learning fusion method… More >

MOHAMAD ZULKEFLEE SABRI¹, JOANNA BOJARSKA², FAI-CHU WONG^3,4, TSUN-THAI CHAI^3,4,*

BIOCELL, Vol.47, No.8, pp. 1727-1742, 2023, DOI:10.32604/biocell.2023.029272 - 28 August 2023

Abstract Molecular dynamics (MD) simulation is a computational technique that analyzes the movement of a system of particles over a given period. MD can provide detailed information about the fluctuations and conformational changes of biomolecules at the atomic level over time. In recent years, MD has been widely applied to the discovery of peptides and peptide-like molecules that may serve as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitors. This review summarizes recent advances in such explorations, focusing on four protein targets: angiotensin-converting enzyme 2 (ACE2), spike protein (S protein), main protease (M^pro), and papain-like protease (PL^pro).… More > Graphic Abstract

Xiaolin Lu^1,*, Xiaolei Miao²

International Journal of Mental Health Promotion, Vol.25, No.9, pp. 1041-1052, 2023, DOI:10.32604/ijmhp.2023.030232 - 10 August 2023

Abstract Background: During the early stages of the COVID-19 pandemic in China, social interactions shifted to online spaces due to lock-downs and social distancing measures. As a result, the impact of online social networking on users’ emotional status has become stronger than ever. This study examines the association between online social networking and Internet users’ emotional status and how offline reality affects this relationship. Methods: The study utilizes cross-sectional online survey data (n = 3004) and Baidu Migration big data from the first 3 months of the pandemic. Two dimensions of online networking are measured: social… More > Graphic Abstract