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  • Open Access

    ARTICLE

    Systolic and Diastolic Strain Measurements Show Left Ventricular Dysfunction in Women with Turner Syndrome

    Allard T. van den Hoven1, Sultan Yilmazer1, Lidia R. Bons1, Roderick W. J. van Grootel1, L. W. Geenen1, An M. van Berendoncks1, Anthonie L. Duijnhouwer2, Hans-Marc J. Siebelink3, Jolien W. Roos-Hesselink1, Annemien E. van den Bosch1,*

    Congenital Heart Disease, Vol.16, No.4, pp. 357-368, 2021, DOI:10.32604/CHD.2021.014462 - 19 April 2021

    Abstract Aim: This study aimed to describe the systolic left ventricular global longitudinal strain (LvGLS) and left ventricular peak early diastolic strain rate (Sre) in adult women with Turner syndrome (TS) and to determine its relationship with exercise capacity and clinical parameters. Methods: In this cross-sectional cohort study, consecutively included adult TS women underwent an electrocardiogram, transthoracic echocardiogram (TTE) and cardiopulmonary exercise test (CPET) on the same day. LvGLS and Sre were measured using 2D speckle tracking analysis (STE) and compared with age-matched healthy female controls. Results: Ninety-four adult women (age 36 ± 13 years) with TS and… More >

  • Open Access

    ARTICLE

    Effect of Exercise-Based Cardiac Rehabilitation on Cardiorespiratory Fitness in Adults with Congenital Heart Disease

    Prisca Eser1,*, Thomas Gruber1, Thimo Marcin1, Claudia Boeni1,2, Kerstin Wustmann3, Christina DeLuigi1, Matthias Greutmann4, Daniel Tobler5, Markus Schwerzmann3, Matthias Wilhelm1

    Congenital Heart Disease, Vol.16, No.1, pp. 73-84, 2021, DOI:10.32604/CHD.2021.013051 - 23 December 2020

    Abstract Background: The purpose of this study was to investigate whether patients with adult congenital heart disease (ACHD) benefit from exercise-based cardiac rehabilitation (CR) short- and long-term with regard to improvement of cardiorespiratory fitness. Methods: Cardiopulmonary exercise tests (CPET) completed by ACHD patients between January 2000 and October 2019 were analysed retrospectively. Linear mixed models were performed for peak oxygen consumption (VO2) with patients as random effect and age, sex, disease classification, preceding surgery (≤3 months) and preceding CR (≤4 weeks for short term and >4 weeks for long term) as fixed effects. Results: 1056 CPETs of 311… More >

  • Open Access

    ARTICLE

    A Smart Wellness Service Platform and Its Practical Implementation

    Umar Farooq1, Intae Ryoo2, Gon Khang1,*

    CMC-Computers, Materials & Continua, Vol.66, No.1, pp. 45-57, 2021, DOI:10.32604/cmc.2020.013035 - 30 October 2020

    Abstract Advances in the field of medical sciences and medical technology, and present-day challenges, such as an aging population, rising medical expenses, and lifestyle-related diseases, have collectively catalyzed a research ecosystem termed “smart wellness.” This article describes the establishment of a smart wellness service platform designed to empower individuals to create a sense of balance in their lives. Step-by-step details include service model, design, and architectural considerations. As a proof of concept, implementation details of a Health Improvement and Management Systems (HIMS) Hub, a Smart Wellness Service Platform deployed in six cities in South Korea, are More >

  • Open Access

    ARTICLE

    Mind-Body Exercises (Yoga/Tai Chi) for Attention-Deficit/Hyperactivity Disorder: A Quantitative Evidence of Experimental Studies

    Erfei Zuo1, Yanjie Zhang2, Qian Yu2, Tianyou Guo2, Can Jiao2, Ye Yu3, Patrick Müller4, Xinli Chi2, Md Mahhub Hossain5, Albert S. Yeung6, Notger G. Müller4, Liye Zou2,*

    International Journal of Mental Health Promotion, Vol.22, No.4, pp. 221-231, 2020, DOI:10.32604/IJMHP.2020.014552 - 22 December 2020

    Abstract Background: Attention-deficit/hyperactivity disorder (ADHD) is a common pediatric psychiatric disorder. Although mindful exercises (Yoga and Tai Chi) have been increasingly accepted as alternative medicine for ADHD, no meta-analytic review has been conducted on this topic. Objective: We systematically and critically evaluated the existing literature regarding the effects of the two most widely practiced mindful exercises on ADHD symptoms and social problems in children and adolescents with ADHD. Methods: Searching literature databases included PubMed, Web of Science, Scope, China National Knowledge Infrastructure and Wanfang. Only randomized controlled trials (RCT) and nonrandomized controlled studies (NRS) that investigated the beneficial… More >

  • Open Access

    ARTICLE

    Comparative Effectiveness of Mind-Body Exercise Versus Cognitive Behavioral Therapy for College Students with Problematic Smartphone Use: A Randomized Controlled Trial

    Chunping Lu1,#, Liye Zou2,#, Benjamin Becker3, Mark D. Griffiths4, Qian Yu2, Si-Tong Chen5, Zsolt Demetrovics6, Can Jiao7, Xinli Chi7, Aiguo Chen8, Albert Yeung9, Shijie Liu10, Yanjie Zhang2,11,*

    International Journal of Mental Health Promotion, Vol.22, No.4, pp. 271-282, 2020, DOI:10.32604/IJMHP.2020.014419 - 22 December 2020

    Abstract Purpose: The purpose of the present study was to compare the effectiveness of mind-body exercise (ME) and cognitive behavioral therapy (CBT) on addiction level and psychological well-being among college students with problematic smartphone use (PSU). Methods: A 12-week randomized controlled study was carried out at a university in central China. A total of 95 PSU college students who met the inclusion criteria were randomly assigned to a ME group (ME, n = 31), CBT group (CBT, n = 30), or control group (CG, n = 34). Both ME intervention and CBT, twice per week for 90… More >

  • Open Access

    ARTICLE

    The Effect of Continued Training with Crocin on Apoptosis Markers in Liver Tissue of High Fat Diet Induced Diabetic Rats

    Zahra Alimanesh1, Zeynab Alimanesh1, Fatemeh Davari2, Saeedeh Shadmehri3, Mozhgan Ahmadi3, Seyed Ali Hosseini4, Sepideh Dolati5,*, Alemeh Hariri Far6

    Molecular & Cellular Biomechanics, Vol.17, No.4, pp. 155-163, 2020, DOI:10.32604/mcb.2020.011532 - 20 October 2020

    Abstract Diabetes mellitus (DM) disease can affect process of apoptosis by increasing oxidative stress, nevertheless exercise and crocin can improve apoptosis; therefore present study aimed to investigate the effect of continued training with crocin on apoptosis markers in liver tissue of diabetic rats. In this experimental study 32 diabetic rats based on fasting glucose divided into four groups of eight rats including: 1) sham, 2) training, 3) crocin, and 4) training with crocin also for investigate the effect of DM induction on apoptosis markers, eight healthy rats assigned in healthy control group. During eight weeks groups… More >

  • Open Access

    ARTICLE

    Laparoscopic Training Exercises Using HTC VIVE

    Ayesha Hoor Chaudhry*, Faisal Bukhari, Waheed Iqbal, Zubair Nawaz, Muhammad Kamran Malik

    Intelligent Automation & Soft Computing, Vol.26, No.1, pp. 53-59, 2020, DOI:10.31209/2019.100000149

    Abstract Laparoscopic surgery is a relatively new field in developing countries. There is a scarcity of laparoscopically trained doctors due to a lack of training and resources available in hospitals. Training and evaluation of medical professionals to develop laparoscopic surgical skills are important and essential as it improves the success rate and reduces the risk during real surgery. The purpose of this research is to develop a series of training exercises based on virtual reality using HTC Vive headset to emulate real-world training of doctors. This virtual training not only gives the trainee doctors mastery in More >

  • Open Access

    ARTICLE

    Chronotropic Response and Pulmonary Function are Associated with Exercise Performance in Children and Adolescents with Repaired Tetralogy of Fallot Independent of Cardiac Function

    Shivani M. Bhatt1,*, Michael L. O’Byrne2, Michael McBride2, Stephen M. Paridon2, Elizabeth Goldmuntz2, Laura Mercer-Rosa2

    Congenital Heart Disease, Vol.15, No.2, pp. 101-115, 2020, DOI:10.32604/CHD.2020.011287 - 23 June 2020

    Abstract Objective: The determinants of exercise capacity in repaired tetralogy of Fallot (rTOF) are multifactorial and remain incompletely understood. This study sought to evaluate the association of chronotropic response with exercise parameters and investigate the determinants of heart rate reserve (HRR) in a cohort of children and adolescents with rTOF. Design: We retrospectively analyzed patients with rTOF, age 8–18 years, who underwent cardiac magnetic resonance (CMR) and cardiopulmonary exercise test (CPET) for research purposes. Linear regression models were performed to test associations among clinical, CMR and CPET parameters. Outcomes included percent-predicted maximum VO2 (%mVO2) and HRR. Results: A total… More >

  • Open Access

    ARTICLE

    Evaluation of Fontan liver disease: Correlation of transjugular liver biopsy with magnetic resonance and hemodynamics

    Jose A. Silva‐Sepulveda1, Yudy Fonseca2, Irine Vodkin3, Gabrielle Vaughn1, Robert Newbury4, Vera Vavinskaya5, Jerry Dwek6, James C. Perry1, Preeti Reshamwala7, Cynthia Baehling8, James Lyon9, Christopher Davis1, Jesse W. Lee1, Hannah El‐Sabrout10, Doaa Shahbah11, Laith Alshawabkeh12, John W Moore1, Howaida El‐Said1

    Congenital Heart Disease, Vol.14, No.4, pp. 600-608, 2019, DOI:10.1111/chd.12770

    Abstract Introduction: Liver fibrosis and cirrhosis are late complications in Fontan palliation. Liver biopsy is the gold standard. The goal of this study is to correlate transjugular liver biopsy (TJLB) in the setting of Fontan palliation with noninvasive testing and hemodynamics.
    Methods: Between August 2014 and July 2017, 49 Fontan patients underwent TJLB. All the patients had hemodynamic evaluation, 28 patients had MRE (magnetic reso‐ nance elastography) and 40 patients had cardiopulmonary exercise test. Histologic liver fibrosis was quantitated using traditional histologic scoring systems and a modi‐ fied Ishak congestive hepatic fibrosis score.
    Results: Median age 17.8 years, median… More >

  • Open Access

    ARTICLE

    Right ventricular and pulmonary vascular function indices for risk stratification of patients with pulmonary regurgitation

    Alexander C. Egbe, William R. Miranda, Patricia A. Pellikka, Sorin V. Pislaru, Barry A. Borlaug, Srikanth Kothapalli, Sindhura Ananthaneni, Harigopal Sandhyavenu, Maria Najam, Mohamed Farouk Abdelsamid, Heidi M. Connolly

    Congenital Heart Disease, Vol.14, No.4, pp. 657-664, 2019, DOI:10.1111/chd.12768

    Abstract Background: We hypothesized that echocardiographic indices of right ventricular to pulmonary artery (RV‐PA) coupling were comparable to cardiac magnetic resonance imaging (CMRI)‐derived RV volumetric indices in predicting disease severity in chronic pulmonary regurgitation (PR).
    Methods: Patients with ≥ moderate PR (2003‐2015) with and without prior CMRI scans were enrolled into the study cohort and validation cohort, respectively. Endpoint was to determine the association between noninvasive RV‐PA coupling in‐ dices (tricuspid annular plane systolic excursion/right ventricular systolic pressure [TAPSE/RVSP] and fractional area change [FAC]/RVSP ratio) and markers of disease severity, and compared this association to that of CMRI‐derived… More >

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