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  • Open Access

    ARTICLE

    Porosity-Impact Strength Relationship in Material Extrusion: Insights from MicroCT, and Computational Image Analysis

    Jia Yan Lim1,2, Siti Madiha Muhammad Amir3, Roslan Yahya3, Marta Peña Fernández2, Tze Chuen Yap1,*

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.070707 - 09 December 2025

    Abstract Additive Manufacturing, also known as 3D printing, has transformed conventional manufacturing by building objects layer by layer, with material extrusion or fused deposition modeling standing out as particularly popular. However, due to its manufacturing process and thermal nature, internal voids and pores are formed within the thermoplastic materials being fabricated, potentially leading to a decrease in mechanical properties. This paper discussed the effect of printing parameters on the porosity and the mechanical properties of the 3D printed polylactic acid (PLA) through micro-computed tomography (microCT), computational image analysis, and Charpy impact testing. The results for both… More >

  • Open Access

    ARTICLE

    Engineering Amorphous Solid Dispersions of Abiraterone Acetate via HPMC HME: A Polymer-Centric Hot-Melt Extrusion Strategy for Formulation-Driven Bioavailability Improvement

    Manisha Choudhari1, Shantanu Damle2, Rajat Vashist1, Ranendra Narayan Saha3, Sunil Kumar Dubey4, Gautam Singhvi1,*

    Journal of Polymer Materials, Vol.42, No.4, pp. 1199-1229, 2025, DOI:10.32604/jpm.2025.072987 - 26 December 2025

    Abstract Abiraterone acetate (ABTA) was approved by the USFDA in 2011 for treating metastatic castration-resistant prostate cancer (mCRPC). ABTA exhibits poor aqueous solubility, inadequate dissolution, low oral bioavailability (<10%), and significant positive food effects. To overcome these limitations, in the present work, ABTA solid dispersions (SDs) were developed by using hot melt extrusion technology (HME) with various grades of hydroxypropyl methylcellulose HME (HPMC HME 15LV and 100LV) at different extrusion temperatures. HPMC HME demonstrated the ability to prevent drug precipitation for up to 120 min compared to the free drug (10 min), sustaining the supersaturation state… More > Graphic Abstract

    Engineering Amorphous Solid Dispersions of Abiraterone Acetate via HPMC HME: A Polymer-Centric Hot-Melt Extrusion Strategy for Formulation-Driven Bioavailability Improvement

  • Open Access

    PROCEEDINGS

    Radio Frequency-Assisted Curing of On-Chip Printed Carbon Nanotube/silicone Heatsinks Produced by Material Extrusion 3D Printing

    Thang Q. Tran1,2, Anubhav Sarmah1, Ethan M. Harkin1, Smita Shivraj Dasari1, Kailash Arole1, Matthew Cupich1, Aniela J. K. Wright1, Hang Li Seet2, Sharon Mui Ling Nai2, Micah J. Green1,3,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.3, pp. 1-2, 2024, DOI:10.32604/icces.2024.012057

    Abstract With the rapid development of high-power integrated electronic devices, many polymer-based thermal management devices have been developed to address the problem of overheating and to improve the reliability and lifetime of electronic devices. Here we demonstrate the material extrusion 3D printing of carbon nanotube (CNT)/silicone heatsinks directly onto electronic devices. CNTs were used as a conductive nanofiller and a rheological modifier to improve thermal and electrical conductivities and the printability of the silicone inks, respectively. Additionally, CNTs are also a radio frequency (RF) susceptor, so the integration of CNTs into the silicone matrix allowed for… More >

  • Open Access

    ARTICLE

    Development of Gelatin-Based Active Packaging and Its Application in Bread Preservation

    Hui Zheng1,2, Xiaohan Chen2, Li Li2, Dawei Qi1, Jiale Wang1, Jiaying Lou1,*, Wenjun Wang1,*

    Journal of Renewable Materials, Vol.11, No.10, pp. 3693-3709, 2023, DOI:10.32604/jrm.2023.027748 - 10 August 2023

    Abstract The issue of plastic pollution has attracted widespread social attention. Gelatin is valued as a degradable bio-based material, especially as an edible active packaging material. However, the commonly used solution-casting filmforming technology limits the mass production of gelatin films. In order to improve the production efficiency and enhance the commercial value of gelatin films, in this study, fish gelatin (FG) particles were successfully blended with essential oils (EOs) to prepare active films by melt extrusion technique, a common method for commercial plastics, and applied to bread preservation. FG and EOs showed good compatibility with each… More > Graphic Abstract

    Development of Gelatin-Based Active Packaging and Its Application in Bread Preservation

  • Open Access

    ARTICLE

    Genotypic Divergence, Photosynthetic Efficiency, Sodium Extrusion, and Osmoprotectant Regulation Conferred Salt Tolerance in Sorghum

    Ashaduzzaman Sagar1 , Md. Sabibul Haque1, Md. Alamgir Hossain1, Md. Nesar Uddin1, Jannat E. Tajkia1, Md. Ashik Mia1, Toufika Hossain Shabi2, Md. Solaiman Ali Fakir1, Md. Abdul Kader3,4,5, Walid Soufan6, Md. Atikur Rahman7, Muhammad Aamir Iqbal8, Mohammad Sohidul Islam9, Ayman El Sabagh10,*, A. K. M. Zakir Hossain1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.8, pp. 2349-2368, 2023, DOI:10.32604/phyton.2023.028974 - 25 June 2023

    Abstract Salt stress is one of the major limitations to modern agriculture that negatively influences plant growth and productivity. Salt tolerant cultivar can provide excellent solution to enhance stress tolerance with plant fitness to unfavorable environments. Therefore, this study was aimed to screen salt tolerant sorghum genotypes through evaluating of different morphological, biochemical, and physiological attributes in response to salinity stress. In this study, we have been evaluated total six sorghum genotypes including Hybrid sorgo, Debgiri, BD-703, BD-706, BD-707, and BD-725 under salt stress (12 dS m−1 NaCl). The response variables included length and weight of root… More >

  • Open Access

    ARTICLE

    Preparation and Characterization of Thermoplastic Starch from Sugar Palm (Arenga pinnata) by Extrusion Method

    Muhammad Ghozali1,2, Yenny Meliana2, Widya Fatriasari3, Petar Antov4, Mochamad Chalid1,*

    Journal of Renewable Materials, Vol.11, No.4, pp. 1963-1976, 2023, DOI:10.32604/jrm.2023.026060 - 01 December 2022

    Abstract Sugar palm (Arenga pinnata) starch is considered an important renewable, biodegradable, and eco-friendly polymer, which is derived from agricultural by-products and residues, with great potential for the development of biocomposite materials. This research was aimed at investigating the development of TPS biocomposites from A. pinnata palm starch using an extrusion process. Palm starch, glycerol, and stearic acid were extruded in a twin-screw extruder. Scanning electron microscopy (SEM) analysis of TPS showed that the starch granules were damaged and gelatinized in the extrusion process. The density of TPS was 1.3695 g/mL, lower than that of palm starch, and… More > Graphic Abstract

    Preparation and Characterization of Thermoplastic Starch from Sugar Palm (<i>Arenga pinnata</i>) by Extrusion Method

  • Open Access

    ARTICLE

    Development of a Novel Extrusion Process for Preparing Rice Straw/LLDPE Composites

    Huicheng Xu, Hao Xie, Weidong Shan, Weihong Wang*

    Journal of Renewable Materials, Vol.11, No.3, pp. 1123-1135, 2023, DOI:10.32604/jrm.2022.023959 - 31 October 2022

    Abstract Straw utilization is a key issue related to agricultural production and air pollution control. In this study, a novel extrusion process was proposed to improve the physical and mechanical properties of the straw-reinforced linear low-density polyethylene (LLDPE) composite. Instead of crushing the straw and mixing it with plastic matrix, the new method mixes straw with plastic matrix in its original form. The intact long rice straws were parallelly spread on the LLDPE film and then rolled up together into a prefabricated roll. The rolls experienced three extrusion processes as follows: (1) twin-screw melting, cooling and… More >

  • Open Access

    VIEWPOINT

    Cell extrusion in development and cancer, what MARCKS the difference for epithelial integrity?

    LUCÍA VELOZ1,2, SANTIAGO A. BOSCH1,3, GONZALO APARICIO1,2,*, FLAVIO R. ZOLESSI1,2,*

    BIOCELL, Vol.46, No.3, pp. 639-644, 2022, DOI:10.32604/biocell.2022.018798 - 18 November 2021

    Abstract Cell extrusion is an active mechanism to eliminate non-viable or supernumerary cells in healthy epithelia. It also plays a role in carcinogenesis, both in tumor growth (apical extrusion) and metastasis (basal extrusion). Embryonic tissues like the neuroepithelium, on the other hand, present rates of proliferation comparable to that of carcinomas, without the occurrence of cell extrusion. However, the downregulation or phosphorylation of actin-modulating proteins like MARCKS, causes extensive neuroepithelial apical cell extrusion. As changes in MARCKS proteins phosphorylation and expression have also been correlated to carcinogenesis, we propose here an integrated model for their functions More >

  • Open Access

    ARTICLE

    Melt Extrusion of Environmentally Friendly Poly(L-lactic acid)/Sodium Metabisulfite Films for Antimicrobial Packaging Applications

    Norma M. P. Machado1, Gustavo C. Melo1, Matheus F. Camargo1, Giulianna G. Feijó1, Bruna M. S. Putton2, Clarice Steffens2, Rogerio L. Cansian2, Luiz A. Pessan1, Francys K. V. Moreira1,*

    Journal of Renewable Materials, Vol.9, No.2, pp. 337-349, 2021, DOI:10.32604/jrm.2021.011081 - 15 December 2020

    Abstract Food packaging materials compounded with antimicrobial additives can substantially diminish the incidence of foodborne diseases. Here, poly(L-lactic acid) (PLA) films containing sodium metabisulfite (NaM) were produced by melt extrusion as an attempt to develop a new biodegradable material with antimicrobial properties for packaging. Life cycle assessment (LCA) simulations revealed that the environmental footprints of the PLA film did not change upon NaM addition, and that NaM is more eco-friendly than silver nanoparticles. The PLA/NaM films with NaM content varying from 0.5 to 5.0 wt.% were characterized by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and… More >

  • Open Access

    RESIDENT’S CORNER

    Spontaneous extrusion of renal calculi presenting as a retroperitoneal abscess

    Patrick Houghton, Amanda Myers, Christian Ericson, David D. Thiel, Timothy D. Lyon

    Canadian Journal of Urology, Vol.27, No.5, pp. 10411-10414, 2020

    Abstract Spontaneous extrusion of a kidney stone is an extremely rare event with few reported cases.We present the unusual case of a 62-year-old female who presented with worsening of fever and fank pain over a 5 day period. Imaging revealed retroperitoneal and abdominal wall abscesses that upon evaluation of prior imaging were attributed to spontaneously extruded kidney stones. Prior reports suggest surgical exploration and extraction is the preferred treatment option for extruded renal calculi. Based on the experience presented here, conservative management may be an attractive frst-line treatment option for patients with extruded renal stones and More >

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