Ziying Huang¹, Ruikang Ma¹, Anning Li², Yufei Cheng¹, Xiaolin Lin², Mengzhi Li³, Yu Zhang², Liping Shi¹, Linlin Dong^1,*

Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2025.074419 - 30 January 2026

Abstract Epimedium is commonly used to treat bone injury and kidney disease, with prenylated flavonol glycosides (PFGs) as its active ingredients. It has attracted much attention due to prominent healthcare and therapeutic effects, but faces problems of adulteration with closely related species and confusion about geographical origins. In this study, multiple technical approaches were employed to identify its genetic characteristics and metabolic differences. Based on DNA barcoding, 20 batches of samples were analyzed. The genetic distances of matK, ITS and psbA-trnH within species were all smaller than those between species, and psbA-trnH along with ITS + psbA-trnH proved most effective… More >

Yingying Lan, Bo Liu^*

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2026.075706 - 29 January 2026

Abstract In this work, the Hierarchical Quadrature Element Method (HQEM) formulation of geometrically exact shells is proposed and applied for geometrically nonlinear analyses of both isotropic and laminated shells. The stress resultant formulation is developed within the HQEM framework, consequently significantly simplifying the computations of residual force and stiffness matrix. The present formulation inherently avoids shear and membrane locking, benefiting from its high-order approximation property. Furthermore, HQEM’s independent nodal distribution capability conveniently supports local p-refinement and flexibly facilitates mesh generation in various structural configurations through the combination of quadrilateral and triangular elements. Remarkably, in lateral buckling… More >

Maddina Dinesh Kumar^1,#, S. U. Mamatha², Khalid Masood³, Nehad Ali Shah^4,#, Se-Jin Yook^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074680 - 29 January 2026

Abstract Fluid dynamic research on rectangular and trapezoidal fins is aimed at increasing heat transfer by means of large surfaces. The trapezoidal cavity form is compared with its thermal and flow performance, and it is revealed that trapezoidal fins tend to be more efficient, particularly when material optimization is critical. Motivated by the increasing need for sustainable energy management, this work analyses the thermal performance of inclined trapezoidal and rectangular porous fins utilising a unique hybrid nanofluid. The effectiveness of nanoparticles in a working fluid is primarily determined by their thermophysical properties; hence, optimising these properties… More >

Burhan Baraklı^1,*, Can Yüzkollar², Tuğrul Taşçı³, İbrahim Yıldırım²

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074292 - 29 January 2026

Abstract Salient object detection (SOD) models struggle to simultaneously preserve global structure, maintain sharp object boundaries, and sustain computational efficiency in complex scenes. In this study, we propose SPSALNet, a task-driven two-stage (macro–micro) architecture that restructures the SOD process around superpixel representations. In the proposed approach, a “split-and-enhance” principle, introduced to our knowledge for the first time in the SOD literature, hierarchically classifies superpixels and then applies targeted refinement only to ambiguous or error-prone regions. At the macro stage, the image is partitioned into content-adaptive superpixel regions, and each superpixel is represented by a high-dimensional region-level… More >

Hyeon-Sik Choi¹, Min Kyu Kim¹, Jiuk Shin², Thomas H.-K. Kang^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074029 - 29 January 2026

Abstract Unbonded post-tensioned (PT) concrete systems are widely used in safety-critical structures, yet modeling practices for prestress implementation and tendon-concrete interaction remain inconsistent. This study investigates the effects of sheath (duct) implementation and confinement assumptions through nonlinear finite element analysis. Four modeling cases were defined, consisting of an explicit sheath without tendon-concrete confinement (S) and three no-sheath variants with different confinement levels (X, N, A). One-way beams and two-way panels were analyzed, and panel blast responses were validated against experimental results. In both beams and panels, average initial stress levels were similar across models, through local More >

Zhuofan Li¹, Daniel H. Pak², James S. Duncan², Liang Liang³, Minliang Liu^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.073757 - 29 January 2026

Abstract Patient-specific finite element analysis (FEA) is a promising tool for noninvasive quantification of cardiac and vascular structural mechanics in vivo. However, inverse material property identification using FEA, which requires iteratively solving nonlinear hyperelasticity problems, is computationally expensive which limits the ability to provide timely patient-specific insights to clinicians. In this study, we present an inverse material parameter identification strategy that integrates deep neural networks (DNNs) with FEA, namely inverse DNN-FEA. In this framework, a DNN encodes the spatial distribution of material parameters and effectively regularizes the inverse solution, which aims to reduce susceptibility to local optima… More >

Firas Mahmood Younis^1,*, Omar Mohammad Hamdoon², Ayad Younis Abdulla¹

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.073483 - 27 January 2026

Abstract This paper presents an experimental analysis of a solar-assisted powered underfloor heating system, designed primarily to boost energy efficiency and achieve reliable desired steady-state temperature in buildings. We thoroughly tested the system’s thermal and operational features by subjecting it to three distinct scenarios that mimicked diverse solar irradiance and environmental conditions. Our findings reveal a strong correlation between variations in solar input and overall system performance. The Solar Fraction (SF), our key energy efficiency metric, varied significantly across the cases, ranging from 63.1% up to 88.7%. This high reliance on renewables resulted in a substantial… More >

SHAOFENG XIONG^1,2, WENKAI LV³, GUOSHENG CAO⁴, LONGSHENG FU¹, WEN LIU³, MENGFAN LEI², YANNI LV^1,5,*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.073401 - 23 January 2026

Abstract Objective: Leucine-rich alpha-2 glycoprotein 1 (Lrg1) could regulate diverse cells in cerebral ischemia-reperfusion. Our study seeks to uncover Lrg1’s impact on endothelial cell heterogeneity via differentiation pathways and transcription factors. Method: The CSOmap model measured cell-to-brain-center distances using single-cell RNA sequencing (scRNA-seq) data in middle cerebral artery occlusion reperfusion (MCAO/R). Monocle2 mapped endothelial differentiation paths. Gene set enrichment analysis (GSEA) analyzed endothelial subcluster variations. Database searches revealed a zinc finger MIZ-type containing 1 protein-frizzled 3 (Zmiz1-Fzd3) promoter interaction. Endothelial cells were transfected with a Fzd3 promoter-luciferase plasmid. Polymerase chain reaction (PCR) and western blotting assessed… More >

Hang Zhang^1,#, Meng-Yuan Chu^1,#, Guohui Lv¹, You-Jie Li¹, Xuhang Liu², Fei Jiao^1,*, Yun-Fei Yan^1,*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.068322 - 23 January 2026

Abstract Objectives: Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, with limited understanding of lncRNA-driven mechanisms in tumor progression. This study aimed to identify differentially expressed lncRNAs in NSCLC tissues and elucidate the functional role of the significantly upregulated RP3-340N1.2 in promoting malignancy. Methods: RNA sequencing was used to screen dysregulated lncRNAs. RP3-340N1.2 was functionally characterized via gain/loss-of-function assays in NSCLC cells, assessing proliferation, migration, and macrophage polarization. Mechanisms of interleukin 6 (IL-6) regulation were explored using cytokine profiling, Actinomycin D assays, and RNA Immunoprecipitation (RIP) assays to study RP3-340N1.2 interactions with… More >

Huan Zhang^1,#, Zhangwendi Xu^1,#, Yien Xu^1,#, Mao Li², Lingrui Liu¹, Caiyun He^1,*, Wenhuan Zhong^1,*, Jiliang Qiu^1,*

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.073079 - 19 January 2026

Abstract Objective: Ring finger protein 145 (RNF145), an E3 ubiquitin ligase, is significantly upregulated in hepatocellular carcinoma (HCC). However, its role in HCC remains unknown. The study aimed to investigate the functions and underlying mechanisms of RNF145 in HCC. Methods: The role of RNF145 in HCC was investigated using data from The Cancer Genome Atlas (TCGA) and in vitro experimental assays. Its oncogenic functions were assessed using the transwell migration assay and the wound-healing assay. The molecular mechanism was explored through protein immunoprecipitation and western blot analyses. Data from public databases were analyzed to correlate RNF145 expression… More >