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  • Open Access

    ARTICLE

    Healing Effect and Underlying Mechanism of Silver Nanoparticles Prepared Using Carboxymethyl Chitosan under Solar Irradiation

    Yi Long1,#,* , Chunling Zhang2,#,*, Lan Chen3,#, Tietao Di2, Lu Chen2, Lisha Tang2, Kaizhong Luo2, Yu Yan1, Pingzhen Tong2, Jie Xiang4

    Journal of Renewable Materials, Vol.9, No.6, pp. 1075-1085, 2021, DOI:10.32604/jrm.2021.014555

    Abstract In our previous study, silver nanoparticles were prepared using AgNO3 and carboxymethyl chitosan (CMCS) which is commercially available with solar irradiation. In this study, the efficacy and safety of silver nanoparticles prepared by this method were evaluated for healing wounds in rats with diabetes. We also attempted to determine the underlying mechanism and influencing factors of the silver nanomaterial preparation method. Compared with growth factors, silver nanoparticles exhibit better healing effects for rats with diabetes. No remnant silver ions were detected in the major organs of these rats after the application of silver nanoparticles. Silver nanoparticles prepared using CMCS are… More >

  • Open Access

    ARTICLE

    The Optimization Study about Fault Self-Healing Restoration of Power Distribution Network Based on Multi-Agent Technology

    Fuquan Huang1, Zijun Liu1, Tinghuang Wang1, Haitai Zhang2, *, Tony Yip3

    CMC-Computers, Materials & Continua, Vol.65, No.1, pp. 865-878, 2020, DOI:10.32604/cmc.2020.010724

    Abstract In order to quickly and accurately locate the fault location of the distribution network and increase the stability of the distribution network, a fault recovery method based on multi-objective optimization algorithm is proposed. The optimization of the power distribution network fault system based on multiagent technology realizes fast recovery of multi-objective fault, solve the problem of network learning and parameter adjustment in the later stage of particle swarm optimization algorithm falling into the local extreme value dilemma, and realize the multi-dimensional nonlinear optimization of the main grid and the auxiliary grid. The system proposed in this study takes power distribution… More >

  • Open Access

    ARTICLE

    Thermally Reversible, Self-Healing Polyurethane Based on Propyl Gallate and Polyurethane Prepolymers with Varied Isocyanate Content

    Haiyang Ding1,2,3,4,5, Xiaohua Yang1,2,3,4,5, Lina Xu1,2,3,4,5, Shouhai Li1,2,3,4,5, Jianling Xia1,2,3,4,5, Mei Li1,2,3,4,5,*

    Journal of Renewable Materials, Vol.8, No.1, pp. 1-11, 2020, DOI:10.32604/jrm.2020.08165

    Abstract Thermosetting polyurethanes are widely used in various fields owing to their excellent elasticity, strength and solvent resistance. Three environmental friendly propyl gallate-based self-healing polyurethanes were prepared from polyurethane prepolymers with varying isocyanate content. The thermal stabilities of the polyurethanes were tested using thermogravimetric analysis. Their self-healing and mechanical properties were analyzed using a universal testing machine and dynamic thermomechanical analysis. The polyurethanes were found with high self-healing ability and excellent mechanical properties due to the absence of phenolic carbamate. These qualities improved with increased isocyanate content and the prolonged selfhealing time. We found, therefore, that the propyl gallate-based polyurethane has… More >

  • Open Access

    ARTICLE

    An extract of Hypericum perforatum induces wound healing through inhibitions of Ca2+ mobilizations, mitochondrial oxidative stress and cell death in epithelial cells: Involvement of TRPM2 channels

    Fuat USLUSOY1, Mustafa NAZIROĞLU2,3,*

    BIOCELL, Vol.43, No.4, pp. 271-283, 2019, DOI:10.32604/biocell.2019.08333

    Abstract The wound is induced by several mechanical and metabolic factors. In the etiology of the wound recovery, excessive oxidative stress, calcium ion (Ca2+) influx, and apoptosis have important roles. Ca2+-permeable TRPM2 channel is activated by oxidative stress. Protective roles of Hypericum perforatum extract (HP) on the mechanical nerve injury-induced apoptosis and oxidative toxicity through regulation of TRPM2 in the experimental animals were recently reported. The potential protective roles in HP treatment were evaluated on the TRPM2-mediated cellular oxidative toxicity in the renal epithelium (MPK) cells. The cells were divided into three groups as control, wound, and wound + HP treatment… More >

  • Open Access

    ARTICLE

    TNFα increases in vitro migration of human HPV18-positive SW756 cervical carcinoma cells

    K. HIDALGO1, I. G. ROJAS2, A. B. PENISSI3, M. I. RUDOLPH1

    BIOCELL, Vol.29, No.3, pp. 303-311, 2005, DOI:10.32604/biocell.2005.29.303

    Abstract TNFα has been associated with both, tumor survival and apoptosis. This cytokine is also involved in promoting cell migration during wound healing and tumorigenesis. SW756 is a HPV18-positive cervical carcinoma cell line, which has been used to study different mechanisms of cervical cancer progression. An in vitro assay of scratch wound healing onto monolayers of SW756 cells was used to assess the effect of TNFα on cell migration into a wound space. It was found that SW756 cells have the ability to migrate, but not proliferate in response to scratch wounding in a serum-free medium supplemented with TNFα. RT-PCR analysis… More >

  • Open Access

    ARTICLE

    The Effect of Cutting Edge Smoothness on Wound Healing Response

    F. Despa1, M. Chioffe1, N. Yu1, C. Spiro2, J. Hicks2, R. C. Lee1

    Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 237-238, 2006, DOI:10.32604/mcb.2006.003.237

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    The β2-Adrenergic Receptor Is a Global Regulator of Wound Healing In Vivo

    C. E. Pullar1, R. R. Isseroff1

    Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 233-234, 2006, DOI:10.32604/mcb.2006.003.233

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    ACL Healing and Regeneration

    L. Yang1, K. L. Paul Sung1

    Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 147-147, 2006, DOI:10.32604/mcb.2006.003.147

    Abstract This article has no abstract. More >

  • Open Access

    ABSTRACT

    Computational Methods of Ultrasound Wave Propagation in Healing Long Bones

    D. I. Fotiadis1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.5, No.2, pp. 85-92, 2008, DOI:10.3970/icces.2008.005.085

    Abstract Quantitative ultrasound has attracted significant interest in the evaluation of bone fracture healing. Animal and clinical studies have demonstrated that the propagation velocity across fractured bones can be used as an indicator of healing. Researchers have recently employed computational methods for modeling wave propagation in bones aiming to gain insight into the underlying mechanisms of wave propagation and to further enhance the monitoring capabilities of ultrasound. In this paper we review the computational studies of ultrasound wave propagation in intact and healing bones. More >

  • Open Access

    ARTICLE

    Structure - Function Relationships in the Stem Cell's Mechanical World B: Emergent Anisotropy of the Cytoskeleton Correlates to Volume and Shape Changing Stress Exposure

    Hana Chang*, Melissa L. Knothe Tate∗,†,‡

    Molecular & Cellular Biomechanics, Vol.8, No.4, pp. 297-318, 2011, DOI:10.3970/mcb.2011.008.297

    Abstract In the preceding study (Part A), we showed that prescribed seeding conditions as well as seeding density can be used to subject multipotent stem cells (MSCs) to volume changing stresses and that changes in volume of the cell are associated with changes in shape, but not volume, of the cell nucleus. In the current study, we aim to control the mechanical milieu of live cells using these prescribed seeding conditions concomitant to delivery of shape changing stresses via fluid flow, while observing adaptation of the cytoskeleton, a major cellular transducer that modulates cell shape, stiffness and remodeling. We hypothesize that… More >

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