A. Tsourkas, R. Weissleder^1,1

Molecular & Cellular Biomechanics, Vol.1, No.2, pp. 133-146, 2004, DOI:10.3970/mcb.2004.001.133

Abstract Traditionally, fluorescent and luminescent reporter proteins have been used as indicators of gene expression and protein localization. However, insightful mutagenesis and protein engineering strategies have transformed these simple passive reporters into active biological sensors. Molecular reporters are now being designed to alter their intrinsic optical properties in response to specific biomolecular interactions. Applications for these novel biological sensors range from monitoring intracellular pH and ion fluxes to detecting protein-protein interactions and enzymatic activity. The ability to monitor the dynamics of intracellular activity in response to external stimuli can help elucidate the cascade of events involved in complex processes such as… More >

Brad Regez, Sridhar Krishnaswamy, Kirk Kuehling

The International Conference on Computational & Experimental Engineering and Sciences, Vol.20, No.3, pp. 67-68, 2011, DOI:10.3970/icces.2011.020.067

Abstract Dr. Brad Regez

Northwestern University, USA More >

Brad Regez¹, Sridhar Krishnaswamy¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.12, No.4, pp. 111-112, 2009, DOI:10.3970/icces.2009.012.111

Abstract Ultrasonic inspection techniques have a proven record of applications during manufacturing and maintenance of metallic and composite aircraft structures. Traditional ultrasonic inspection techniques use a point-by-point scanning method to acquire a full-field image. This scanning method is slow and inadequate in satisfying modern manufacturing and maintenance time line requirements. The next generation of ultrasonic inspection eliminates the need for point-by-point scanning using an imaging array that is capable of displaying thousands of points to create a full-field image in real-time.
In this study, a next generation dual-channel ultrasonic imaging system is used for real-time three-dimensional evaluation of small composite aerospace… More >

C.C. Chia¹, S.G. Jang¹, J.R. Lee², D.J. Yoon²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.11, No.2, pp. 29-30, 2009, DOI:10.3970/icces.2009.011.029

Abstract An ultrasonic propagation imaging (UPI) system consisted of a Q-switched Nd-YAG pulsed laser with 20 Hz-repetition rate and a motorized tilting mirror system for rapid scanning of target was developed. The system which requires neither reference data nor fixed focal length could be used for health monitoring of curved structures. If combined with a fiber acoustic wave PZT (FAWPZT) sensor, it could be used to perform inspection on hot target structures, which present formidable challenges to the usage of contact piezoelectric transducers mainly due to the Curie temperature limitation of transducers and debonding problem due to the mismatch of coefficient… More >

R. E. Meyers¹, K. S. Deacon¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.8, No.3, pp. 101-106, 2008, DOI:10.3970/icces.2008.008.101

Abstract A new type of imaging, Quantum ghost imaging, is described that is based on the measurement of photons reflected from an object . A CCD array is placed facing a chaotic light source and gated by a photon counting detector that simply counts all randomly reflected photons from an object. A ``ghost'' image of the object is then observed in the gated CCD. This interesting demonstration is not only useful for practical applications, such as x-ray lensless imaging, but is also important from a fundamental point of view. It further explores the nonclassical two-photon interference nature of thermal light ghost… More >

Osorio Rivera Fray León¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.7, No.2, pp. 63-76, 2008, DOI:10.3970/icces.2008.007.063

Abstract In the development context of a project about a system of selection uchuva for export by means of artificial vision whose objective is to provide an electromechanical system to able to select uchuvas by searching on its physical appearance, some algorithms have been developed to extract the necessary details beginning with the image of the acquired fruit using a camera. As a result, it must be able to determine if the visualized uchuva presents some symptom (insects, fungus, and deterioration) that indicates if it should be discharged. More >

R.E. Meyers¹, K.S. Deacon¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.3, No.4, pp. 211-216, 2007, DOI:10.3970/icces.2007.003.211

Abstract Using a CCD camera we investigated and successfully achieved quantum ghost imaging of the stencil letters "ARL" placed in front of a photon bucket detector from photons which did not interact with the stencil letter object. We investigated the role of speckle spatial size and time scales in resolving images. The process suggests new mathematical paradigms and important applications for quantum ghost imaging . More >

Jiaqi Zhang¹, Kehai Liu^2,*, Chang Gao¹, Zhanjun Wu¹, Yuebin Zheng¹, Dongyue Gao³

Structural Durability & Health Monitoring, Vol.13, No.1, pp. 41-59, 2019, DOI:10.32604/sdhm.2019.05142

Abstract Probability-based diagnostic imaging (PDI) is one of the most well-known damage identification methods using guided waves. It is usually applied to diagnose damage in plates. The previous studies were dependent on the certain damage index (DI) which is always calculated from the guided wave signals. In conventional methods, DI is simply defined by comparing the real-time data with the baseline data as reference. However, the baseline signal is easily affected by varying environmental conditions of structures. In this paper, a reference-free diagnostic imaging method is developed to avoid the influence of environmental factors, such as temperature and load conditions. The… More >

Qingyu Wang¹, Dalin Tang^1,2,*, Gador Canton³, Zheyang Wu², Thomas S. Hatsukami⁴, Kristen L. Billiar⁵, Chun Yuan⁶

Molecular & Cellular Biomechanics, Vol.15, No.4, pp. 189-201, 2018, DOI:10.32604/mcb.2018.04572

Abstract Cardiovascular diseases are closely linked to atherosclerotic plaque development and rupture. Assessment of plaque vulnerability is of fundamental significance to cardiovascular research and disease diagnosis, prevention, treatment and management. Magnetic resonance image (MRI) data of carotid atherosclerotic plaques from 8 patients (5 male, 3 female; age: 62-83, mean=71) were acquired at the University of Washington (UW), Seattle by the Vascular Imaging Laboratory (VIL) with written informed consent obtained. Patient-specific vessel material properties were quantified using Cine MRI data for modeling use. 3D thin-layer models were used to obtain plaque stress and strain for plaque assessment. A stress-based plaque vulnerability index… More >

Chunliu He¹, Jiaqiu Wang², Yuxiang Huang¹, Tongjing Zhu¹, Yuehong Miao¹, Zhiyong Li^1,2*

Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 23-36, 2016, DOI:10.3970/mcb.2016.013.027

Abstract Fibrous cap thickness (FCT) is seen as critical to plaque vulnerability. Therefore, the development of automatic algorithms for the quantification of FCT is for estimating cardiovascular risk of patients. Intravascular optical coherence tomography (IVOCT) is currently the only in vivo imaging modality with which FCT, the critical component of plaque vulnerability, can be assessed accurately. This study was aimed to discussion the correlation between the texture features of OCT images and the FCT in lipid-rich atheroma. Methods: Firstly, a full automatic segmentation algorithm based on unsupervised fuzzy c means (FCM) clustering with geometric constrains was developed to segment the ROIs… More >