MENNA AL-ADL^1,*, MAGDY M. YOUSSEF¹, AHMED EL-SEBAIE², SHERIF REFAAT³, AFAF EL-SAID⁴

Oncology Research, Vol.32, No.4, pp. 785-797, 2024, DOI:10.32604/or.2024.047021

Abstract Cytochromes P450 (CYPs) play a prominent role in catalyzing phase I xenobiotic biotransformation and account for about 75% of the total metabolism of commercially available drugs, including chemotherapeutics. The gene expression and enzyme activity of CYPs are variable between individuals, which subsequently leads to different patterns of susceptibility to carcinogenesis by genotoxic xenobiotics, as well as differences in the efficacy and toxicity of clinically used drugs. This research aimed to examine the presence of the CYP2B6*9 polymorphism and its possible association with the incidence of B-CLL in Egyptian patients, as well as the clinical outcome after receiving cyclophosphamide chemotherapy. DNA… More > Graphic Abstract

Yi Shi, Fangfang Shangguan^*, Jing Xiao^*

International Journal of Mental Health Promotion, Vol.25, No.12, pp. 1257-1263, 2023, DOI:10.32604/ijmhp.2023.030516

Abstract Background: Social support is related to depression, but the gender differences and related factors that contribute to low social support among adolescents with subthreshold depression remain to be elucidated. This study explores the relationship between social support and depression, in addition to the gender difference in the incidence of low social support among adolescents with subthreshold depression and its related factors. Methods: A total of 371 Chinese adolescents with subthreshold depression were recruited. All subjects were rated on the Social Support Scale for Adolescents, the Response Style Scale, the Self-Perception Profile for Children, the Individualism-collectivism scale. Results: Binary logistic regression… More >

Muhammad Shoaib Arif^1,2,*, Kamaleldin Abodayeh¹, Yasir Nawaz²

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.2, pp. 1405-1425, 2024, DOI:10.32604/cmes.2023.028946

Abstract This work aimed to construct an epidemic model with fuzzy parameters. Since the classical epidemic model does not elaborate on the successful interaction of susceptible and infective people, the constructed fuzzy epidemic model discusses the more detailed versions of the interactions between infective and susceptible people. The next-generation matrix approach is employed to find the reproduction number of a deterministic model. The sensitivity analysis and local stability analysis of the system are also provided. For solving the fuzzy epidemic model, a numerical scheme is constructed which consists of three time levels. The numerical scheme has an advantage over the existing… More >

Md. Salah Uddin Afsar¹, Mohammad Rashed Iqbal Faruque^1,*, Sabirin Abdullah¹, Mohammad Tariqul Islam²

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 455-469, 2023, DOI:10.32604/cmc.2023.036655

Abstract This study proposed a new royal crown-shaped polarisation insensitive double negative triple band microwave range electromagnetic metamaterial absorber (MA). The primary purpose of this study is to utilise the exotic characteristics of this perfect metamaterial absorber (PMA) for microwave wireless communications. The fundamental unit cell of the proposed MA consists of two pentagonal-shaped resonators and two inverse C-shaped metallic components surrounded by a split ring resonator (SRR). The bottom thin copper deposit and upper metallic resonator surface are disjoined by an FR-4 dielectric substrate with 1.6 mm thickness. The CST MW studio, a high-frequency electromagnetic simulator has been deployed for… More >

YI-NONG CHEN^1,#, YING-LIN CHEN^1,#, WAN-MING CHEN^2,3, MINGCHIH CHEN^2,3, BEN-CHANG SHIA^2,3, JENQ-YUH KO^1,4, SZU-YUAN WU^{2,3,5,6,7,8,9,10,11,*}

Oncology Research, Vol.31, No.1, pp. 23-34, 2023, DOI:10.32604/or.2022.028449

Abstract This study aimed to examine the association between the use of H1-antihistamines (AHs) and head and neck cancer (HNC) risk in patients with type 2 diabetes mellitus (T2DM). Data from the National Health Insurance Research Database of Taiwan were analyzed for the period from 2008 to 2018. A propensity-score-matched cohort of 54,384 patients each in the AH user and nonuser groups was created and analyzed using Kaplan-Meier method and Cox proportional hazards regression. The results showed that the risk of HNC was significantly lower in AH users (adjusted hazard ratio: 0.55, 95% CI: 0.48 to 0.64) and the incidence rate… More >

Attaullah^1,*, Kamil Zeb¹, Abdullah Mohamed²

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.2, pp. 1661-1685, 2023, DOI:10.32604/cmes.2023.023059

Abstract Mathematical modelling has been extensively used to measure intervention strategies for the control of contagious conditions. Alignment between different models is pivotal for furnishing strong substantiation for policymakers because the differences in model features can impact their prognostications. Mathematical modelling has been widely used in order to better understand the transmission, treatment, and prevention of infectious diseases. Herein, we study the dynamics of a human immunodeficiency virus (HIV) infection model with four variables: S (t), I (t), C (t), and A (t) the susceptible individuals; HIV infected individuals (with no clinical symptoms of AIDS); HIV infected individuals (under ART with… More >

Chao Shang, Dongkui Xu^*

Oncologie, Vol.24, No.4, pp. 649-663, 2022, DOI:10.32604/oncologie.2022.027640

Abstract All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence rate was 66.4/100,000 in developed… More >

Danqing Huang^*

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.3, pp. 845-854, 2023, DOI:10.32604/fdmp.2022.020314

Abstract A two-dimensional mathematical model is used to simulate the influence of water flow on the piers of a bridge for different incidence angles. In particular, a finite volume method is used to discretize the Navier-Stokes control equations and calculate the circumferential pressure coefficient distribution on the bridge piers’ surface. The results show that the deflection of the flow is non-monotonic. It first increases and then decreases with an increase in the skew angle. More >

Ankush Kapoor¹, Pradeep Kumar^2,*, Ranjan Mishra³

CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 341-361, 2023, DOI:10.32604/cmc.2023.028874

Abstract Frequency selective surfaces (FSSs) play an important role in wireless systems as these can be used as filters, in isolating the unwanted radiation, in microstrip patch antennas for improving the performance of these antennas and in other 5G applications. The analysis and design of the double concentric ring frequency selective surface (DCRFSS) is presented in this research. In the sub-6 GHz 5G FR1 spectrum, a computational synthesis technique for creating DCRFSS based spatial filters is proposed. The analytical tools presented in this study can be used to gain a better understanding of filtering processes and for constructing the spatial filters.… More >

Jae Hee Seol^1,4,#, Se Yong Jung^1,#, Jae Young Choi¹, Han Ki Park², Young Hwan Park², Nam Kyun Kim^1,3,*

Congenital Heart Disease, Vol.17, No.5, pp. 569-578, 2022, DOI:10.32604/chd.2022.018436

Abstract Objective: Junctional ectopic tachycardia is common after cardiac surgery for congenital heart disease. However, its incidence and related risk factors in infants after cardiac surgery are not well known. The objective of this study was to determine the overall incidence and related risk factors for junctional ectopic tachycardia in neonates and infants. Methods: We enrolled a total of 271 patients aged <1 year who underwent open cardiac surgery at Severance Cardiovascular Hospital from January 2018 to December 2020. Exclusion criteria were immediate postoperative mortality, other arrhythmias detected in the perioperative period, and prematurity. Result: The overall incidence of junctional ectopic… More >