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  • Open Access


    Differential Diagnosis between Primary Intracranial Melanoma and Cerebral Cavernoma in Crohn’s Disease: A Case Report and Literature Review

    Roberta Costanzo1, Vishal Parmar2, Salvatore Marrone1, Domenico Gerardo Iacopino1, Giovanni Federico Nicoletti3, Giuseppe Emmanuele Umana4, Gianluca Scalia3,*

    Oncologie, Vol.24, No.4, pp. 937-942, 2022, DOI:10.32604/oncologie.2022.027155

    Abstract Primary intracranial melanomas are rare, with a challenging diagnosis based only on clinical and imaging features. The authors described the case of an intracerebral right parieto-temporal melanoma mimicking a cavernoma in a patient affected by Crohn’s disease. A 67-year-old female patient with Crohn’s disease and small bowel stenosis was hospitalized for surgical removal of the terminal ileum and latero-lateral ileo-colic anastomosis. During postoperative week 1, the patient developed psychomotor agitation followed by altered consciousness. An urgent brain CT showed a right intracerebral parieto-temporal hemorrhage with intralesional calcifications. The patient underwent a decompressive craniectomy with hematoma drainage and a complete resection… More >

  • Open Access


    The function of ubiquitin-specific protease 31 in intracerebral hemorrhage


    BIOCELL, Vol.46, No.6, pp. 1545-1555, 2022, DOI:10.32604/biocell.2022.017544

    Abstract Intracerebral hemorrhage (ICH) is the most serious type of stroke. High level of thrombin is found in the ICH. Ubiquitin-specific protease (USP) 31, a member of deubiquitinating enzymes family, has been found to negatively regulate the NF-κB pathway. However, the function of USP31 in ICH remains largely unknown. In the present study, the mRNA and protein expression levels of USP31 were measured by real-time PCR and western blot. Flow cytometry was used to measure cell apoptosis and the level of reactive oxygen species (ROS). In the current study, we found the mRNA level of USP31 was decreased in peripheral blood… More >

  • Open Access


    Liver Lesions and Acute Intracerebral Hemorrhage Detection Using Multimodal Fusion

    Osama S. Faragallah1,*, Abdullah N. Muhammed2, Taha S. Taha3, Gamal G. N. Geweid4,5

    Intelligent Automation & Soft Computing, Vol.30, No.1, pp. 215-225, 2021, DOI:10.32604/iasc.2021.019058

    Abstract Medical image fusion is designed to help physicians in their decisions by providing them with a preclinical image with enough information. Accurate assessment and effective treatment of the disease reduce the time it takes to relieve the symptoms of the disease. This article utilizes an effective data fusion approach to work on two different imaging modalities; computed tomography (CT) and magnetic resonance imaging (MRI). The data fusion approach is based on the combination of singular value decomposition (SVD) and the Fast Discrete Curvelet Transform (FDCT) techniques to reduce processing time during the fusion process. The SVD-FDCT data fusion approach is… More >

  • Open Access


    A Novel Deep Neural Network for Intracranial Haemorrhage Detection and Classification

    D. Venugopal1, T. Jayasankar2, Mohamed Yacin Sikkandar3, Mohamed Ibrahim Waly3, Irina V. Pustokhina4, Denis A. Pustokhin5, K. Shankar6,*

    CMC-Computers, Materials & Continua, Vol.68, No.3, pp. 2877-2893, 2021, DOI:10.32604/cmc.2021.015480

    Abstract Data fusion is one of the challenging issues, the healthcare sector is facing in the recent years. Proper diagnosis from digital imagery and treatment are deemed to be the right solution. Intracerebral Haemorrhage (ICH), a condition characterized by injury of blood vessels in brain tissues, is one of the important reasons for stroke. Images generated by X-rays and Computed Tomography (CT) are widely used for estimating the size and location of hemorrhages. Radiologists use manual planimetry, a time-consuming process for segmenting CT scan images. Deep Learning (DL) is the most preferred method to increase the efficiency of diagnosing ICH. In… More >

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