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  • Open Access

    ARTICLE

    Flexible ureterorenoscopy vs. mini percutaneous nephrolithotomy for kidney stones in chronic kidney damage: a prospective study

    Nazım Furkan Günay*, Mücahit Gelmiş, Çağlar Dizdaroğlu, Abdullah Esmeray, Ufuk Çağlar, Ömer Sarılar, Faruk Özgör

    Canadian Journal of Urology, Vol.33, No.2, pp. 281-290, 2026, DOI:10.32604/cju.2025.072419 - 20 April 2026

    Abstract Objectives: Chronic kidney disease (CKD) poses unique challenges in the management of renal stones, and high-quality evidence to guide treatment decisions is limited. This study aimed to compare the effects of flexible ureteroscopy (f-URS) and mini-percutaneous nephrolithotomy (m-PCNL) on perioperative outcomes and long-term renal function in patients with CKD and renal stones. Methods: This prospective randomized study included 60 CKD patients with renal stones measuring 1–4 cm. Participants were randomized into f-URS (n = 24) and m-PCNL (n = 36) groups. Baseline demographics, stone characteristics, and perioperative parameters were recorded. Stone-free rate (SFR) was defined… More >

  • Open Access

    ARTICLE

    Pulsed solid-state thulium: YAG laser compared to holmium: YAG laser during mini-PCNL

    Benedikt Becker1,2, Sophia Hook1, Carla Dapper1, Julius Bergmann1, Christopher Netsch1, Simon Filmar1,*

    Canadian Journal of Urology, Vol.33, No.2, pp. 271-279, 2026, DOI:10.32604/cju.2025.072386 - 20 April 2026

    Abstract Background: Holmium: yttrium-aluminum-garnet (Ho: YAG) laser technology has long been employed for urinary stone fragmentation; however, its limitations have prompted the exploration of alternative systems such as thulium lasers. This study aims to compare a novel pulsed solid-state Thulium: YAG (Tm: YAG) laser to the standard Ho: YAG laser in Mini-percutaneous nephrolithotomy (Mini-PCNL) lithotripsy for renal calculi. Methods: In total, 100 patients undergoing Mini-PCNL were enrolled in this clinical trial. Fifty patients treated with a holmium laser were selected from a retrospective database. These patients were compared to fifty patients who were prospectively enrolled and… More >

  • Open Access

    ARTICLE

    Nonlinear association between estimated glucose disposal rate and kidney stones: a cross-sectional study

    Zhenzhen Yang1,#, Linxin Jiang2,#, Shan Yin3,*

    Canadian Journal of Urology, Vol.33, No.2, pp. 261-270, 2026, DOI:10.32604/cju.2025.069717 - 20 April 2026

    Abstract Objectives: Kidney stone disease is increasingly prevalent and may be linked to metabolic factors such as insulin resistance, but there is currently no direct evidence connecting estimated glucose disposal rate (eGDR) to kidney stones. This study aimed to investigate the relationship between eGDR and kidney stone prevalence. Methods: We conducted a cross-sectional analysis utilizing data from the National Health and Nutrition Examination Survey (NHANES) from 2007–2018, including 29,753 participants aged 20 years and older. Weighted multivariable logistic regression and nonlinear models were employed to assess the relationship between eGDR and self-reported kidney stone history. Results: Among… More > Graphic Abstract

    Nonlinear association between estimated glucose disposal rate and kidney stones: a cross-sectional study

  • Open Access

    ARTICLE

    Is postoperative routine thoracic imaging necessary to detect thoracic complications in patients undergoing supracostal mini percutaneous nephrolithotomy (m-PCNL) surgery?

    Abdullah Esmeray, Huseyin Burak Yazili*, Mucahit Gelmis, Nazim Furkan Gunay, Caglar Dizdaroglu, Faruk Ozgor, Yasar Pazir, Ufuk Caglar

    Canadian Journal of Urology, Vol.33, No.1, pp. 165-171, 2026, DOI:10.32604/cju.2025.069657 - 28 February 2026

    Abstract Objectives: Supracostal access during percutaneous nephrolithotomy (PCNL) increases the risk of pulmonary complications. Although routine postoperative thoracic imaging is commonly performed to detect these events, its clinical necessity remains controversial. This study aimed to assess the necessity of routine postoperative thoracic imaging for detecting pulmonary complications in patients undergoing supracostal mini percutaneous nephrolithotomy (m-PCNL) surgery. Methods: A retrospective analysis was conducted on data from patients who underwent supracostal m-PCNL between 2017 and 2022 in a tertiary center. Excluding patients under 18, with kidney/skeletal anomalies, or active thoracic disease, 112 eligible patients were included. Patients were… More >

  • Open Access

    ARTICLE

    Improving surgical outcome reporting in lithiasis surgery: a comparative analysis of comprehensive complication index and clavien-dindo classification

    Stamatios Katsimperis1,*, Lazaros Tzelves1, Georgios Feretzakis2, Themistoklis Bellos1, Panagiotis Deligiannis1, Andreas Skolarikos1, Athanasios Papatsoris1, Iraklis Mitsogiannis1

    Canadian Journal of Urology, Vol.32, No.4, pp. 271-282, 2025, DOI:10.32604/cju.2025.066395 - 29 August 2025

    Abstract Background: Accurate complication reporting in endourology remains challenging, with the Clavien-Dindo Classification and Comprehensive Complication Index being the most commonly used systems. This study aimed to compare surgical outcomes and complication reporting in ureterolithotripsy (URL), percutaneous nephrolithotomy (PCNL), and extracorporeal shock wave lithotripsy (ESWL) using both systems. Methods: This prospective, single-center, non-interventional study included 473 patients undergoing URL, PCNL, or ESWL from October 2022 to October 2024. Demographic, stone-related, and procedural variables were recorded. Complications were classified using the CDC, and cumulative morbidity was assessed using CCI. Statistical analyses, including univariate and multivariate regression, were… More >

  • Open Access

    RESIDENT’S CORNER

    Case of drug-induced kidney stone from overuse of phenazopyridine

    Suraj Pursnani, Necole M. Streeper

    Canadian Journal of Urology, Vol.31, No.3, pp. 11911-11913, 2024

    Abstract Drug-induced nephrolithiasis represents only 1%-2% of stone cases. Here we focus on drugs capable of crystallizing and forming stone, specifically phenazopyridine (Pyridium/Azo). This is a case of a patient who presented with a stone conglomerate in the right proximal ureter and underwent definitive treatment. Interestingly, the stone had a purple hue with FTIR spectroscopy showing stone composition of calcium oxalate (monohydrate and dihydrate) and a material resembling phenazopyridine. We retrospectively learned that she used multiple extended courses of phenazopyridine over 3 months. More >

  • Open Access

    ARTICLE

    An Optimized Transfer Learning Model Based Kidney Stone Classification

    S. Devi Mahalakshmi*

    Computer Systems Science and Engineering, Vol.44, No.2, pp. 1387-1395, 2023, DOI:10.32604/csse.2023.027610 - 15 June 2022

    Abstract The kidney is an important organ of humans to purify the blood. The healthy function of the kidney is always essential to balance the salt, potassium and pH levels in the blood. Recently, the failure of kidneys happens easily to human beings due to their lifestyle, eating habits and diabetes diseases. Early prediction of kidney stones is compulsory for timely treatment. Image processing-based diagnosis approaches provide a greater success rate than other detection approaches. In this work, proposed a kidney stone classification method based on optimized Transfer Learning(TL). The Deep Convolutional Neural Network (DCNN) models More >

  • Open Access

    ARTICLE

    Thulium versus holmium for in situ lower pole laser lithotripsy

    Matthew I. Buell1,*, Akin S. Amasyali1,*, Natalie Chen2, Joshua D. Belle1, Mohamed Keheila1, Elizabeth A. Baldwin1, Cayde Ritchie1, D. Duane Baldwin1

    Canadian Journal of Urology, Vol.29, No.6, pp. 11371-11377, 2022

    Abstract Introduction: During in situ lower pole laser lithotripsy, the dependent location may result in increased challenge fragmenting stones and a risk for stone regrowth if residual fragments remain. The purpose of this study was to compare the thulium fiber laser (TFL) with the holmium laser (HL) for in situ lower pole lithotripsy.
    Materials and methods: In a 3D printed kidney benchtop model, sixty 1 cm BegoStones were placed in the lower pole and fragmented in situ until fragments passed through a 2 x 2 mm mesh. Laser lithotripsy was performed using twelve energy, frequency and fiber size… More >

  • Open Access

    RESIDENT’S CORNER

    Celiac plexus block for chronic flank pain: a case series

    William W. French1, Joseph M. Kuebker2, Xiang Shu3, Christopher M. Sobey4, Ryan S. Hsi2

    Canadian Journal of Urology, Vol.28, No.1, pp. 10556-10559, 2021

    Abstract Non-obstructive, chronic flank pain in urologic patients can be a challenging problem to manage. In this series, we examined the efficacy of celiac plexus blockade in providing pain relief and reducing opiate use in 14 adult urology patients with non-obstructive flank pain for > 1 year. Demographic, clinical, and procedural variables were collected from the medical record for retrospective analysis. Subjective improvement in pain occurred in 11 individuals (79%), and 5 (50%) were able to reduce their daily morphine equivalent dose (MED). Celiac plexus blockade is a viable option for symptomatic relief in urologic patients More >

  • Open Access

    ARTICLE

    Use of prescription drug monitoring program to audit opioid prescribing patterns for patients with symptomatic nephrolithiasis

    Rahima Khatun1, Matthew Galida2, Necole M. Streeper2

    Canadian Journal of Urology, Vol.28, No.1, pp. 10542-10546, 2021

    Abstract Introduction: The opioid epidemic is a growing problem in the United States. There is a high rate of opioid oversupply for treatment of symptomatic nephrolithiasis, partly due to patients being seen by multiple providers. In Pennsylvania, there are efforts to integrate a prescription drug monitoring program (PDMP) within the electronic medical record (EMR). The objectives of this study were to evaluate prescribing practices for opioids for symptomatic nephrolithiasis and the incidence of prescriptions not documented within the EMR.
    Materials and methods: Adults who presented for treatment of symptomatic nephrolithiasis were sequentially evaluated from May - October 2017… More >

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