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  • Open Access


    SDN-Enabled Content Dissemination Scheme for the Internet of Vehicles

    Abida Sharif1, Muhammad Imran Sharif1, Muhammad Attique Khan2, Nisar Ali2, Abdullah Alqahtani3, Majed Alhaisoni4, Ye Jin Kim5, Byoungchol Chang6,*

    CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 2383-2396, 2023, DOI:10.32604/cmc.2023.033894

    Abstract The content-centric networking (CCN) architecture allows access to the content through name, instead of the physical location where the content is stored, which makes it a more robust and flexible content-based architecture. Nevertheless, in CCN, the broadcast nature of vehicles on the Internet of Vehicles (IoV) results in latency and network congestion. The IoV-based content distribution is an emerging concept in which all the vehicles are connected via the internet. Due to the high mobility of vehicles, however, IoV applications have different network requirements that differ from those of many other networks, posing new challenges. Considering this, a novel strategy… More >

  • Open Access


    DNA methylation as a mediator of epigenetic regulation in the pathogenesis and precision medicine of osteoarthritis: An updated review


    BIOCELL, Vol.47, No.4, pp. 761-772, 2023, DOI:10.32604/biocell.2023.026698

    Abstract The pathophysiology of osteoarthritis (OA) is multifactorial, with the primary risk factors being obesity, age, environmental variables, and genetic predisposition. The available evidence suggests that genetic diversity does not adequately account for all clinical characteristics and heterogeneity of OA. Genetics has emerged as a nascent and crucial area of research in OA. The epigenetic module presents a potential link between genetic and environmental risk factors and the susceptibility and pathogenesis of OA. As a critical epigenetic alteration, DNA methylation has been shown to have an important role in the etiology of OA and is a viable biomarker for predicting disease… More >

  • Open Access


    Effect of Positive Workplace Gossip on Employee Silence: Psychological Safety as Mediator and Promotion-Focused as Moderator

    Ganli Liao1, Qianqiu Wang1, Yi Li2,*

    International Journal of Mental Health Promotion, Vol.24, No.2, pp. 237-249, 2022, DOI:10.32604/ijmhp.2022.017610

    Abstract The development of electronic information technology has made workplace gossip more ubiquitous. As a part of interpersonal communication on informal occasions, positive workplace gossip affects individuals’ mood, cognition, and behaviors. In light of this and based on the Social Interdependence Theory, the study proposed that positive workplace gossip has a negative effect on employee silence, and psychological safety mediates this relationship. In addition, the promotion-focused moderates the relationship between psychological safety and employee silence. Based on a two-wave sampling design from 311 innovative enterprises employees, the results of Structural Equation Model by AMOS 22.0 and Mplus 7.0 supported all the… More >

  • Open Access


    Investigating the Role of Trust Dimension as a Mediator on CC-SaaS Adoption

    Hiba Jasim Hadi*, Mohd Adan Omar, Wan Rozaini Sheik Osman

    Intelligent Automation & Soft Computing, Vol.29, No.2, pp. 373-386, 2021, DOI:10.32604/iasc.2021.018207

    Abstract The public sector of Iraq has been struggling from poor management of resources and numerous difficulties that affect its governmental organization’s development, such as financial issues resulting from corruption, insecurity, and the lack of IT resources and infrastructure. Thus, cloud computing Software as a Service (CC-SaaS) can be a useful solution to help governmental organizations increase their service efficiency through the adoption of low-cost technology and provision of better services. The adoption of CC-SaaS remains limited in Iraqi public organizations due to numerous challenges, including privacy and protection, legal policy, and trust. Trust was found to be an effective facilitator… More >

  • Open Access


    Effect of Perceived Organizational Support on Fatigue of Chinese Nurses during the COVID-19 Pandemic: Resilience as a Mediator

    Na Zhang1, Dingxin Xu2, Jingjing Li3,*, Zhenxing Gong4

    International Journal of Mental Health Promotion, Vol.23, No.2, pp. 243-254, 2021, DOI:10.32604/IJMHP.2021.015487

    Abstract As working for the nurse is believed to be one of the most stressful professions, nurses are particularly at risk of experiencing fatigue. Especially during the COVID-19 pandemic, fatigue among nurses may affect physical and mental health seriously, which is attracting increasing attention of researchers and clinical practitioners to find effective prevention measures to alleviate nurses’ fatigue. This study aims to investigate the mediational effect of resilience on the relationship between nurses’ perceived organizational support and fatigue. A total of 476 nurses from secondary and above hospitals in Hebei province, China during March and April in 2020, were investigated with… More >

  • Open Access


    Unpacking the Associations between Traumatic Events and Depression among Chinese Elderly: Two Dimensions of Aging Attitudes as Mediators and Moderators

    Chaoxin Jiang*

    International Journal of Mental Health Promotion, Vol.23, No.2, pp. 231-242, 2021, DOI:10.32604/IJMHP.2021.015253

    Abstract Traumatic events have been considered significant risk factors for older adults’ mental health, but the mediating mechanism and moderating effect of aging attitudes that underlie this relationship have yet been completely investigated. The attitudes of the elderly toward aging can be divided into two closely related but conceptually different dimensions, including positive and negative. Positive aging attitudes refer to optimistic feelings and experiences about aging, whereas negative attitudes toward aging are related to detrimental thoughts and sensations experienced about the increasing age. The purpose of this study is to explore the mediating and moderating roles of these two dimensions of… More >

  • Open Access


    Self-Compassion as a Mediator in the Effect of Dispositional Mindfulness on Anxiety and Aggressiveness in College Students with Left-Behind Experience

    Si Yu1, Chunyang Zhang2, Yijun Lin1, Qian Zhang3, Wei Xu1,*

    International Journal of Mental Health Promotion, Vol.22, No.2, pp. 71-81, 2020, DOI:10.32604/IJMHP.2020.011194

    Abstract Few studies have comprehensively explored the mechanism of the association between dispositional mindfulness and the process of internalization and externalization. Given that dispositional mindfulness can enhance the level of self-acceptance, the present study investigated the role of self-compassion in the effect of dispositional mindfulness on anxiety and aggressiveness among college students with left-behind experience (LBE). A total of 385 Chinese college students with LBE reported their level of dispositional mindfulness, anxiety symptoms, aggressiveness, and self-compassion. Dispositional mindfulness was negatively associated with anxiety and aggressiveness after controlling for gender, age, and whether they are the only child in family. Additionally, self-compassion… More >

  • Open Access


    Cysteine proteinases of Trypanosoma cruzi: from digestive enzymes to programmed cell death mediators


    BIOCELL, Vol.30, No.3, pp. 479-490, 2006, DOI:10.32604/biocell.2006.30.479

    Abstract Trypanosoma cruzi, the parasite causing Chagas disease, contains a number of proteolytic enzymes. The recent completion of the genome sequence of the T. cruzi CL Brener clone suggests the presence of 70 cysteine peptidases, 40 serine peptidases (none of them from the chymotrypsin family), about 250 metallopeptidases (most leishmanolysin homologues), 25 threonine peptidases, and only two aspartyl peptidases, none of them from the pepsin family. The cysteine peptidases belong to 7 families of Clan CA, 3 families of Clan CD, and one each of Clans CE and CF. In Clan CA, the C1 family is represented by cruzipains 1 and… More >

  • Open Access


    Negative Pressure-induced Secretion of Inflammatory Mediators by Cultured Middle Ear Epithelial Cells: Relevance to Eustachian Tube Dysfunction and Otitis Media with Effusion

    P. A. Hebda1, M. R. Barsic1, J. E. Dohar1

    Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 231-232, 2006, DOI:10.32604/mcb.2006.003.231

    Abstract This article has no abstract. More >

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