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  • Open Access

    ARTICLE

    Psychological capital and positive academic emotions as mediators between school connectedness and academic engagement

    Niya Chen1,#, Lei Ren2,3,#, Xinyi Wei4, Yaning Guo5, Chuanjun Liu1, Li Guo5, Yinchuan Jin5,6,*

    Journal of Psychology in Africa, Vol.35, No.5, pp. 635-640, 2025, DOI:10.32604/jpa.2025.065773 - 24 October 2025

    Abstract This study utilized a mediation model to examine the role of psychological capital and positive academic emotions in the relationship between school connectedness and academic engagement in adolescents. A sample of 389 Chinese adolescents (Mage = 13.43; 51.2% females) completed the Utrecht Work Engagement Scale-Student (UWES-S), the Achievement Emotions Questionnaire (AEQ), the Positive Psychological Capital Scale (PPCS), and the School Connectedness Scale (SCS). Structural equation modeling analysis yielded findings to suggest that higher school connectedness is associated with academic engagement. Psychological capital was associated with positive emotions, and higher psychological capital partially mediated the relationship between More >

  • Open Access

    ARTICLE

    Self-Esteem as a Mediator: Analyzing Its Impact on Parental Attachment and Adolescent Delinquency

    Mahshid Manouchehri1,2,*, Musheer A. Aljaberi3,4, Yi-Ching Lin5, Aiche Sabah6, Amira Mohammed Ali7, Chung-Ying Lin8,9,*

    International Journal of Mental Health Promotion, Vol.27, No.7, pp. 1013-1028, 2025, DOI:10.32604/ijmhp.2025.061088 - 31 July 2025

    Abstract Background: While various factors contributing to delinquency have been explored, the role of self-esteem in this specific context has received little attention. Hence, this study aims to investigate the complex issue of adolescent delinquency in Iran by focusing on the mediating role of self-esteem in the relationship between parental attachment and delinquent behavior. Methods: Using the multistage cluster random sampling method, the research involved 528 high school students in Tehran. Each student completed validated scales assessing their parental attachment, self-esteem, and delinquency at school. Multiple regression analyses with the Sobel test and bootstrapping method were… More >

  • Open Access

    ARTICLE

    Hypoxia-induced exosomal lncRNA-PVT1 as a biomarker and mediator of EMT in hepatocellular carcinoma

    LIBO LIANG1, XINYI WANG2,3,4, YUPING ZENG2,3,4, HAO CHEN2,3,4, WEN ZHOU1, HONGYING MU2,3,4, GA LIAO5,6,*

    Oncology Research, Vol.33, No.6, pp. 1405-1421, 2025, DOI:10.32604/or.2024.056708 - 29 May 2025

    Abstract Objectives: Exosomal long noncoding RNAs (lncRNAs) might facilitate epithelial–mesenchymal transition (EMT) in liver cancer after transarterial chemoembolization (TACE), thereby enhancing tumor cell invasiveness and migration. This study investigated the prognostic role of plasma exosomal long noncoding RNA-plasmacytoma variant translocation 1 (lncRNA-PVT1) in TACE treated hepatocellular carcinoma (HCC). Methods: Plasma exosomal lncRNA-PVT1 was evaluated via qPCR before and after TACE. Hepatoma cell behavior was investigated in different HCC cell lines. A lncRNA-PVT1 plasmid was synthesized and overexpressed, and si-lncRNA PVT1 was transfected into poorly invasive cells to reveal its influence on cell characteristics. The lncRNA-PVT1–FoxM1 interaction… More > Graphic Abstract

    Hypoxia-induced exosomal lncRNA-PVT1 as a biomarker and mediator of EMT in hepatocellular carcinoma

  • Open Access

    ARTICLE

    Linking proactive personality to strengths use: The mediator of psychological safety and the moderator of exploitative leadership

    Wenyin Yang1, Zhijie Xu2, Yang Liu2,*

    Journal of Psychology in Africa, Vol.35, No.1, pp. 43-49, 2025, DOI:10.32604/jpa.2025.065880 - 30 April 2025

    Abstract Drawing upon the Conservation of Resources theory, this study investigated the relationship between proactive personality and strengths use, as well as the mediating role of psychological safety and the moderating role of exploitative leadership within this relationship. Data were collected from 368 employees (females = 57.61%; mean age = 32.35; SD = 6.31) working in various organizations in China at two points in time with a two-week interval. We conducted structural equation modeling and a moderated mediation path analysis to test our hypotheses. The results demonstrated that proactive personality is positively related to strengths use More >

  • Open Access

    ARTICLE

    The Effect of Performance Pressure on Employee Well-Being: Mediator of Workplace Anxiety and Moderator of Vocational Delay of Gratification

    Ting Wen1, Sainan Mao1, Xiaoqian Fan2,*, Jiayi Wu3

    International Journal of Mental Health Promotion, Vol.27, No.4, pp. 591-606, 2025, DOI:10.32604/ijmhp.2025.057726 - 30 April 2025

    Abstract Background: In the field of organizational behavior, various aspects that have an impact on employee well-being gradually become a focus of attention. Among them, performance pressure, which is a component of workplace stressors that has a great influence on employees’ job performance as well as well-being, has been little studied. Therefore, this paper constructs a research model, which uses workplace anxiety as a mediating variable and vocational delay of gratification as a moderating variable, to explore the impact of performance pressure on employee well-being. Methods: Reliable data were collected by questionnaire method and data analysis… More >

  • Open Access

    REVIEW

    Non-coding RNAs as potential mediators of resistance to lung cancer immunotherapy and chemotherapy

    JIAHUI WANG1,#, HONGCHENG GE2,3,#, ZHENGYUAN YU1,*, LINGZHI WU1,*

    Oncology Research, Vol.33, No.5, pp. 1033-1054, 2025, DOI:10.32604/or.2024.058256 - 18 April 2025

    Abstract Lung cancer is a common cause of cancer-related death globally. The majority of lung cancer patients initially benefit from chemotherapy and immunotherapy. However, as the treatment cycle progresses and the disease evolves, the emergence of acquired resistance leads to treatment failure. Many researches have shown that non-coding RNAs (ncRNAs) not only influence lung cancer progression but also act as potential mediators of immunotherapy and chemotherapy resistance in lung cancer, mediating drug resistance by regulating multiple targets and pathways. In addition, the regulation of immune response by ncRNAs is dualistic, forming a microenvironment for inhibits/promotes More >

  • Open Access

    ARTICLE

    Scarcity and Mental Health—Multiple Mediators of Sleep Quality and Life Satisfaction

    Na Liu1, Yan Zhang2, Junxiu Wang3,4,*

    International Journal of Mental Health Promotion, Vol.26, No.6, pp. 449-462, 2024, DOI:10.32604/ijmhp.2024.049334 - 28 June 2024

    Abstract Background: In the current social environment, scarcity, as a universally present objective state, profoundly impacts individuals’ decision-making and health through the subjective feeling it induces, known as a “scarcity mindset.” Particularly, the feeling of scarcity related to money and sleep time is not only widespread but also directly linked to an individual’s mental health. Purpose: This study aims to delve into the relationship between the feeling of scarcity and mental health, with a specific focus on the relationship between the feeling of money scarcity or sleep time scarcity and mental health, as well as the… More >

  • Open Access

    ARTICLE

    SDN-Enabled Content Dissemination Scheme for the Internet of Vehicles

    Abida Sharif1, Muhammad Imran Sharif1, Muhammad Attique Khan2, Nisar Ali2, Abdullah Alqahtani3, Majed Alhaisoni4, Ye Jin Kim5, Byoungchol Chang6,*

    CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 2383-2396, 2023, DOI:10.32604/cmc.2023.033894 - 31 March 2023

    Abstract The content-centric networking (CCN) architecture allows access to the content through name, instead of the physical location where the content is stored, which makes it a more robust and flexible content-based architecture. Nevertheless, in CCN, the broadcast nature of vehicles on the Internet of Vehicles (IoV) results in latency and network congestion. The IoV-based content distribution is an emerging concept in which all the vehicles are connected via the internet. Due to the high mobility of vehicles, however, IoV applications have different network requirements that differ from those of many other networks, posing new challenges. More >

  • Open Access

    REVIEW

    DNA methylation as a mediator of epigenetic regulation in the pathogenesis and precision medicine of osteoarthritis: An updated review

    QIAO ZHOU1,2,3, JIAN LIU2,4, LING XIN4, YANYAN FANG2,4, LEI WAN2,4, DAN HUANG2,4, JINCHEN GUO1, JIANTING WEN2,4

    BIOCELL, Vol.47, No.4, pp. 761-772, 2023, DOI:10.32604/biocell.2023.026698 - 08 March 2023

    Abstract The pathophysiology of osteoarthritis (OA) is multifactorial, with the primary risk factors being obesity, age, environmental variables, and genetic predisposition. The available evidence suggests that genetic diversity does not adequately account for all clinical characteristics and heterogeneity of OA. Genetics has emerged as a nascent and crucial area of research in OA. The epigenetic module presents a potential link between genetic and environmental risk factors and the susceptibility and pathogenesis of OA. As a critical epigenetic alteration, DNA methylation has been shown to have an important role in the etiology of OA and is a More >

  • Open Access

    ARTICLE

    Effect of Positive Workplace Gossip on Employee Silence: Psychological Safety as Mediator and Promotion-Focused as Moderator

    Ganli Liao1, Qianqiu Wang1, Yi Li2,*

    International Journal of Mental Health Promotion, Vol.24, No.2, pp. 237-249, 2022, DOI:10.32604/ijmhp.2022.017610 - 18 January 2022

    Abstract The development of electronic information technology has made workplace gossip more ubiquitous. As a part of interpersonal communication on informal occasions, positive workplace gossip affects individuals’ mood, cognition, and behaviors. In light of this and based on the Social Interdependence Theory, the study proposed that positive workplace gossip has a negative effect on employee silence, and psychological safety mediates this relationship. In addition, the promotion-focused moderates the relationship between psychological safety and employee silence. Based on a two-wave sampling design from 311 innovative enterprises employees, the results of Structural Equation Model by AMOS 22.0 and More >

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