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  • Open Access

    ARTICLE

    Encoder-Guided Latent Space Search Based on Generative Networks for Stereo Disparity Estimation in Surgical Imaging

    Guangyu Xu1,2, Siyuan Xu3, Siyu Lu4,*, Yuxin Liu1, Bo Yang1, Junmin Lyu5, Wenfeng Zheng1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 4037-4053, 2025, DOI:10.32604/cmes.2025.074901 - 23 December 2025

    Abstract Robust stereo disparity estimation plays a critical role in minimally invasive surgery, where dynamic soft tissues, specular reflections, and data scarcity pose major challenges to traditional end-to-end deep learning and deformable model-based methods. In this paper, we propose a novel disparity estimation framework that leverages a pretrained StyleGAN generator to represent the disparity manifold of Minimally Invasive Surgery (MIS) scenes and reformulates the stereo matching task as a latent-space optimization problem. Specifically, given a stereo pair, we search for the optimal latent vector in the intermediate latent space of StyleGAN, such that the photometric reconstruction… More >

  • Open Access

    REVIEW

    Deep Learning in Medical Image Analysis: A Comprehensive Review of Algorithms, Trends, Applications, and Challenges

    Dawa Chyophel Lepcha1,*, Bhawna Goyal2,3, Ayush Dogra4, Ahmed Alkhayyat5, Prabhat Kumar Sahu6, Aaliya Ali7, Vinay Kukreja4

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1487-1573, 2025, DOI:10.32604/cmes.2025.070964 - 26 November 2025

    Abstract Medical image analysis has become a cornerstone of modern healthcare, driven by the exponential growth of data from imaging modalities such as MRI, CT, PET, ultrasound, and X-ray. Traditional machine learning methods have made early contributions; however, recent advancements in deep learning (DL) have revolutionized the field, offering state-of-the-art performance in image classification, segmentation, detection, fusion, registration, and enhancement. This comprehensive review presents an in-depth analysis of deep learning methodologies applied across medical image analysis tasks, highlighting both foundational models and recent innovations. The article begins by introducing conventional techniques and their limitations, setting the… More >

  • Open Access

    ARTICLE

    Deep Architectural Classification of Dental Pathologies Using Orthopantomogram Imaging

    Arham Adnan1, Muhammad Tuaha Rizwan1, Hafiz Muhammad Attaullah1,2,*, Shakila Basheer3, Mohammad Tabrez Quasim4

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5073-5091, 2025, DOI:10.32604/cmc.2025.068797 - 23 October 2025

    Abstract Artificial intelligence (AI), particularly deep learning algorithms utilizing convolutional neural networks, plays an increasingly pivotal role in enhancing medical image examination. It demonstrates the potential for improving diagnostic accuracy within dental care. Orthopantomograms (OPGs) are essential in dentistry; however, their manual interpretation is often inconsistent and tedious. To the best of our knowledge, this is the first comprehensive application of YOLOv5m for the simultaneous detection and classification of six distinct dental pathologies using panoramic OPG images. The model was trained and refined on a custom dataset that began with 232 panoramic radiographs and was later… More >

  • Open Access

    ARTICLE

    Lightweight Residual Multi-Head Convolution with Channel Attention (ResMHCNN) for End-to-End Classification of Medical Images

    Sudhakar Tummala1,2,*, Sajjad Hussain Chauhdary3, Vikash Singh4, Roshan Kumar5, Seifedine Kadry6, Jungeun Kim7,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 3585-3605, 2025, DOI:10.32604/cmes.2025.069731 - 30 September 2025

    Abstract Lightweight deep learning models are increasingly required in resource-constrained environments such as mobile devices and the Internet of Medical Things (IoMT). Multi-head convolution with channel attention can facilitate learning activations relevant to different kernel sizes within a multi-head convolutional layer. Therefore, this study investigates the capability of novel lightweight models incorporating residual multi-head convolution with channel attention (ResMHCNN) blocks to classify medical images. We introduced three novel lightweight deep learning models (BT-Net, LCC-Net, and BC-Net) utilizing the ResMHCNN block as their backbone. These models were cross-validated and tested on three publicly available medical image datasets:… More >

  • Open Access

    ARTICLE

    MMIF: Multimodal Medical Image Fusion Network Based on Multi-Scale Hybrid Attention

    Jianjun Liu1, Yang Li2,*, Xiaoting Sun3,*, Xiaohui Wang1, Hanjiang Luo2

    CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3551-3568, 2025, DOI:10.32604/cmc.2025.066864 - 23 September 2025

    Abstract Multimodal image fusion plays an important role in image analysis and applications. Multimodal medical image fusion helps to combine contrast features from two or more input imaging modalities to represent fused information in a single image. One of the critical clinical applications of medical image fusion is to fuse anatomical and functional modalities for rapid diagnosis of malignant tissues. This paper proposes a multimodal medical image fusion network (MMIF-Net) based on multiscale hybrid attention. The method first decomposes the original image to obtain the low-rank and significant parts. Then, to utilize the features at different More >

  • Open Access

    REVIEW

    Deep Learning in Biomedical Image and Signal Processing: A Survey

    Batyrkhan Omarov1,2,3,4,*

    CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2195-2253, 2025, DOI:10.32604/cmc.2025.064799 - 23 September 2025

    Abstract Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing, enabling automated lesion detection, physiological monitoring, and therapy planning with accuracy that rivals expert performance. This survey reviews the principal model families as convolutional, recurrent, generative, reinforcement, autoencoder, and transfer-learning approaches as emphasising how their architectural choices map to tasks such as segmentation, classification, reconstruction, and anomaly detection. A dedicated treatment of multimodal fusion networks shows how imaging features can be integrated with genomic profiles and clinical records to yield more robust, context-aware predictions. To support clinical adoption, we outline post-hoc explainability More >

  • Open Access

    REVIEW

    From Spatial Domain to Patch-Based Models: A Comprehensive Review and Comparison of Multimodal Medical Image Denoising Algorithms

    Apoorav Sharma1, Ayush Dogra2,*, Bhawna Goyal3, Archana Saini2, Vinay Kukreja2

    CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 367-481, 2025, DOI:10.32604/cmc.2025.066481 - 29 August 2025

    Abstract To enable proper diagnosis of a patient, medical images must demonstrate no presence of noise and artifacts. The major hurdle lies in acquiring these images in such a manner that extraneous variables, causing distortions in the form of noise and artifacts, are kept to a bare minimum. The unexpected change realized during the acquisition process specifically attacks the integrity of the image’s quality, while indirectly attacking the effectiveness of the diagnostic process. It is thus crucial that this is attended to with maximum efficiency at the level of pertinent expertise. The solution to these challenges… More >

  • Open Access

    ARTICLE

    Efficient Wound Classification Using YOLO11n: A Lightweight Deep Learning Approach

    Fathe Jeribi1,2, Ayesha Siddiqa3,*, Hareem Kibriya4, Ali Tahir1, Nadim Rana1

    CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 955-982, 2025, DOI:10.32604/cmc.2025.065853 - 29 August 2025

    Abstract Wound classification is a critical task in healthcare, requiring accurate and efficient diagnostic tools to support clinicians. In this paper, we investigated the effectiveness of the YOLO11n model in classifying different types of wound images. This study presents the training and evaluation of a lightweight YOLO11n model for automated wound classification using the AZH dataset, which includes six wound classes: Background (BG), Normal Skin (N), Diabetic (D), Pressure (P), Surgical (S), and Venous (V). The model’s architecture, optimized through experiments with varying batch sizes and epochs, ensures efficient deployment in resource-constrained environments. The model’s architecture… More >

  • Open Access

    ARTICLE

    A Hybrid CNN-Transformer Framework for Normal Blood Cell Classification: Towards Automated Hematological Analysis

    Osama M. Alshehri1, Ahmad Shaf2,*, Muhammad Irfan3,*, Mohammed M. Jalal4, Malik A. Altayar4, Mohammed H. Abu-Alghayth5, Humood Al Shmrany6, Tariq Ali7, Toufique A. Soomro8, Ali G. Alkhathami9

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 1165-1196, 2025, DOI:10.32604/cmes.2025.067150 - 31 July 2025

    Abstract Background: Accurate classification of normal blood cells is a critical foundation for automated hematological analysis, including the detection of pathological conditions like leukemia. While convolutional neural networks (CNNs) excel in local feature extraction, their ability to capture global contextual relationships in complex cellular morphologies is limited. This study introduces a hybrid CNN-Transformer framework to enhance normal blood cell classification, laying the groundwork for future leukemia diagnostics. Methods: The proposed architecture integrates pre-trained CNNs (ResNet50, EfficientNetB3, InceptionV3, CustomCNN) with Vision Transformer (ViT) layers to combine local and global feature modeling. Four hybrid models were evaluated on… More >

  • Open Access

    ARTICLE

    Enhancing 3D U-Net with Residual and Squeeze-and-Excitation Attention Mechanisms for Improved Brain Tumor Segmentation in Multimodal MRI

    Yao-Tien Chen1, Nisar Ahmad1,*, Khursheed Aurangzeb2

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 1197-1224, 2025, DOI:10.32604/cmes.2025.066580 - 31 July 2025

    Abstract Accurate and efficient brain tumor segmentation is essential for early diagnosis, treatment planning, and clinical decision-making. However, the complex structure of brain anatomy and the heterogeneous nature of tumors present significant challenges for precise anomaly detection. While U-Net-based architectures have demonstrated strong performance in medical image segmentation, there remains room for improvement in feature extraction and localization accuracy. In this study, we propose a novel hybrid model designed to enhance 3D brain tumor segmentation. The architecture incorporates a 3D ResNet encoder known for mitigating the vanishing gradient problem and a 3D U-Net decoder. Additionally, to… More > Graphic Abstract

    Enhancing 3D U-Net with Residual and Squeeze-and-Excitation Attention Mechanisms for Improved Brain Tumor Segmentation in Multimodal MRI

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