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  • Open Access

    REVIEW

    The pathogenesis of chronic subdural hematoma in the perspective of neomembrane formation and related mechanisms

    MINGYUE HUANG1,#, JUNFEI DAI1,#, XIANLIANG ZHONG2, JIN WANG2, JIANZHONG XU2, BO DU2,*

    BIOCELL, Vol.48, No.6, pp. 889-896, 2024, DOI:10.32604/biocell.2024.050097 - 10 June 2024

    Abstract Chronic subdural hematoma (CSDH) is a disease characterized by capsuled blood products that progressively occupy the intracranial space, causing intracranial hypertension and compression in the brain. CSDH frequently occurs in all demographics, especially in the elderly, but the pathogenesis of CSDH remains unclear. In this review, we discuss the origin, development, and current treatment strategies of CSDH. For the first time, we analyzed the cellular and molecular compositions of hematoma membranes with a focus on neomembrane formation, a complex early-stage interactive event in hematoma pathogenesis. We hypothesize that in patients with CSDH, dural border cells… More >

  • Open Access

    REVIEW

    New insight into the role of exosomes in idiopathic membrane nephropathy

    JIANHONG LIU1,#, KAI HE2,#, HAN WANG3,#, XIAOHONG CHENG1,*

    BIOCELL, Vol.48, No.1, pp. 21-32, 2024, DOI:10.32604/biocell.2023.045631 - 30 January 2024

    Abstract Exosomes, nanoscale extracellular vesicles (EVs) derived from the invagination of the endosomal membrane, are secreted by a majority of cell types. As carriers of DNA, mRNA, proteins, and microRNAs, exosomes are implicated in regulating biological activities under physiological and pathological conditions. Kidney-derived exosomes, which vary in origin and function, may either contribute to the pathogenesis of disease or represent a potential therapeutic resource. Membranous nephropathy (MN), an autoimmune kidney disease characterized by glomerular damage, is a predominant cause of nephrotic syndrome. Notably, MN, especially idiopathic membranous nephropathy (IMN), often results in end-stage renal disease (ESRD),… More > Graphic Abstract

    New insight into the role of exosomes in idiopathic membrane nephropathy

  • Open Access

    ARTICLE

    Hydrogen Permeation Characteristics of Pd-Cu Membrane in Plasma Membrane Reactor

    Muhd Hadi Iskandar Abd Razak*, Motoki Tsuda, Yukio Hayakawa, Shinji Kambara

    Energy Engineering, Vol.121, No.2, pp. 259-272, 2024, DOI:10.32604/ee.2023.043615 - 25 January 2024

    Abstract Hydrogen is an alternative energy source that has the potential to replace fossil fuels. One of the hydrogen applications is as a material for Polymer Electrolyte Membrane Fuel Cells (PEMFC) in fuel cell vehicles. High-purity hydrogen can be obtained using a hydrogen separation membrane to prevent unwanted contaminants from potentially harming the PEMFC components. In this study, we fabricated a plasma membrane reactor and investigated the permeation performance of a hydrogen separation membrane in a plasma membrane reactor utilizing atmospheric pressure plasma. The result showed the hydrogen permeation rate increasing with time as reactor temperature More >

  • Open Access

    ARTICLE

    Analysis of the Influence of Geometrical Parameters on the Performance of a Proton Exchange Membrane Fuel Cell

    Guodong Zhang1, Huifang Tao1, Da Li1, Kewei Chen2, Guoxiang Li1,*, Shuzhan Bai1, Ke Sun1,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.1, pp. 219-237, 2024, DOI:10.32604/fdmp.2023.025566 - 08 November 2023

    Abstract A suitable channel structure can lead to efficient gas distribution and significantly improve the power density of fuel cells. In this study, the influence of two channel design parameters is investigated, namely, the ratio of the channel width to the bipolar plate ridge width (i.e., the channel ridge ratio) and the channel depth. The impact of these parameters is evaluated with respect to the flow pattern, the gas composition distribution, the temperature field and the fuel cell output capability. The results show that a decrease in the channel ridge ratio and an increase in the More >

  • Open Access

    ARTICLE

    Image acquisition and interpretation of 18F-DCFPyL (piflufolastat F 18) PET/CT: How we do it

    Steven P. Rowe1,2,3, Andrew F. Voter1,4, Rudolf A. Werner1,5, Katherine A. Zukotynski6,7,8, Martin G. Pomper1,2,3, Michael A. Gorin9, Lilja B. Solnes1,3

    Canadian Journal of Urology, Vol.30, No.1, pp. 11432-11437, 2023

    Abstract Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET) is rapidly becoming widely accepted as the standard-of-care for imaging of men with prostate cancer. Labeled indications for regulatoryapproved agents include primary staging and recurrent disease in men at risk of metastases. The first commercial PSMA PET agent to become available was 18F-DCFPyL (piflufolastat F 18), a radiofluorinated small molecule with high-affinity for PSMA. The regulatory approval of 18F-DCFPyL hinged upon two key, multi-center, registration trials, OSPREY (patient population: highrisk primary staging) and CONDOR (patient population: biochemical recurrence). In this manuscript, we will (1) review key findings More >

  • Open Access

    ARTICLE

    Effect of Tetramethylurea (TMU) on Polysulfone Membrane Performance for Atrazine-containing Wastewater Treatment

    NIKITA GUPTA, SARITA KALLA, Z.V.P. MURTHY*

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 317-328, 2023, DOI:10.32381/JPM.2023.40.3-4.12

    Abstract Tetramethylurea (TMU) is a good solvent for organic substances and has received little attention as compared to other solvents. The TMU is a polar solution and is one of the molecules with an amphiphilic character. In the present work, an attempt has been made to use TMU as an additive in the preparation of nanofiltration membranes to improve the hydrophilicity of the membrane. The polysulfone membrane has been modified by incorporating different concentrations of TMU (0, 0.5, and 1 wt.%) in order to check the rejection of atrazine in water. This study aim is to More >

  • Open Access

    PROCEEDINGS

    The Mechanical Property of 2D Materials and Potential Application in Gas Separation

    Dong Li1,*, Yonggang Zheng1, Hongwu Zhang1, Hongfei Ye1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.2, pp. 1-1, 2023, DOI:10.32604/icces.2023.09714

    Abstract The family of 2D transition-metal oxides and dichalcogenides with 1H phase (1H-MX2) has sparked great interest from the perspective of basic physics and applied science. Interestingly, their performances could be further regulated and improved through strain engineering. Effective regulation is founded on a wellunderstood mechanical performance, however, the large number of 1H-MX2 materials has not yet been revealed. Here, a general theoretical model is constructed based on the molecular mechanics, which provides an effective and rapid analytical algorithm for evaluating the mechanical properties of the entire family of 1H-MX2. The validity of the constructed model is verified… More >

  • Open Access

    PROCEEDINGS

    Direct Numerical Simulation of Electroconvection near an Ion-Selective Membrane Under Magnetic Field

    Jinxiang Cai1, Gaojin Li1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.1, pp. 1-1, 2023, DOI:10.32604/icces.2023.09833

    Abstract We study the effect of magnetic field on the electro-hydrodynamics of ion transport in a liquid electrolyte near an ion-selective membrane using direct numerical simulation. Ion transport across the ion selective membrane plays an essential role in many electro-hydrodynamic and electro-microfluidic systems. Above a critical voltage, electroconvective instability occurs near the membrane surface, causing vortical flows in liquid electrolyte which enhances the mixing of cations and anions, increases the ion transport efficiency and causes current fluctuations. When the system is under a magnetic field, the Lorentz force generated by the ion movement can significantly change… More >

  • Open Access

    ARTICLE

    Carbon Capture from Flue Gas Based on the Combination of Non-Contact Hydrophobic Porous Ceramic Membrane and Bubbling Absorption

    Yongde Luo, Jiang Jin*, Hua Zhang*

    Journal of Renewable Materials, Vol.11, No.7, pp. 3143-3153, 2023, DOI:10.32604/jrm.2023.027396 - 05 June 2023

    Abstract A hybrid system combined with a non-contact membrane and bubbling absorption is proposed to capture CO2 from flue gas. The non-contact way of membrane and liquid absorbent effectively avoids the reduction of gas diffusion flux through the membrane. High-porosity ceramic membranes in hybrid systems are used for gas-solid separation in fuel gas treatment. Due to the high content of H2O and cement dust in the flue gas of the cement plant, the membrane is hydrophobically modified by polytetrafluoroethylene (PTFE) to improve its anti-water, anti-fouling, and self-cleaning performances. The results show that the diffusion flux of CO2 through More >

  • Open Access

    ARTICLE

    Calcitriol induces post-thawed bovine sperm capacitation

    ANA CECILIA LIAUDAT, FRANCISCA EBEL, BIANCA ANA OPIZZO, MARINA AURORA GONZALEZ, DAMIÁN BLOIS, PABLO BOSCH#, NANCY RODRIGUEZ#,*

    BIOCELL, Vol.47, No.5, pp. 1135-1143, 2023, DOI:10.32604/biocell.2023.027628 - 10 April 2023

    Abstract Background: Capacitation is a set of physiological changes sperms undergo to acquire fertilizing capacity. In vivo, this process is directly associated with high calcium levels in sperm cytoplasm. Calcitriol, the vitamin D hypercalcemic metabolite, is related to human sperm motility, capacitation, and acrosome reaction. This work aimed to study the effect of calcitriol on bull sperm quality parameters and capacitation. Methods: One million freeze-thawed spermatozoa were obtained from different bulls and treated with 20 nM of calcitriol for 30 min. Untreated cells (negative control) and treated ones with calcitriol or heparin (100 µg/mL, positive capacitation control) were… More >

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