Saher Manzoor¹, Muhammad Waseem Ashraf^1,*, Shahzadi Tayyaba², Muhammad Imran Tariq^3,*, M. Khalid Hossain⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.2, pp. 1007-1052, 2023, DOI:10.32604/cmes.2022.022093

Abstract The progress of membrane technology with the development of membranes with controlled parameters led to porous membranes. These membranes can be formed using different methods and have numerous applications in science and technology. Anodization of aluminum in this aspect is an electro-synthetic process that changes the surface of the metal through oxidation to deliver an anodic oxide layer. This process results in a self-coordinated, exceptional cluster of round and hollow formed pores with controllable pore widths, periodicity, and thickness. Categorization in barrier type and porous type films, and different methods for the preparation of membranes, have been discussed. After the… More > Graphic Abstract

DIEGO MASONE^1,2,*

BIOCELL, Vol.47, No.1, pp. 1-14, 2023, DOI:10.32604/biocell.2023.024146

Abstract The inflexible concept of membrane curvature as an independent property of lipid structures is today obsolete. Lipid bilayers behave as many-body entities with emergent properties that depend on their interactions with the environment. In particular, proteins exert crucial actions on lipid molecules that ultimately condition the collective properties of the membranes. In this review, the potential of enhanced molecular dynamics to address cell-biology problems is discussed. The cases of membrane deformation, membrane fusion, and the fusion pore are analyzed from the perspective of the dimensionality reduction by collective variables. Coupled lipid-protein interactions as fundamental determinants of large membrane remodeling events… More >

CHAO WANG^1,2, JUNWEI WANG¹, FANQIAN SONG^1,2, HANRUO LIU³, LIYAO SUN^1,2, XI WEI^1,2, TAO ZHENG¹, HUA QIAN², XIAOGUANG LI², WEIHUA ZHANG⁴, XIANLING TANG^1,*, PING LIU^1,*

BIOCELL, Vol.47, No.1, pp. 143-154, 2023, DOI:10.32604/biocell.2023.023585

Abstract Objective: Age-relate cataract (ARC) is a disease of the eyes with no effective drugs to prevent or treat patients. The aim of the present study is to determine whether histone H3, αA-crystallin (CRYAA), β-galactosidase (GLB1), and p53 are involved in the pathogenesis of ARC. Methods: A total of 99 anterior lens capsules (ALCs) of patients with ARC of various nuclear grades, ultraviolet models of ALCs, and two human lens epithelial cell lines (FHL-124 and SRA01/04) were used, and the expression of histone H3, CRYAA, GLB1, and p53 were detected by immunoblotting and reverse transcription and real time-quantitative polymerase chain reaction.… More >

Jiageng Zhang¹, Zhengfeng Wang², Jiguang Huang¹, Chao Cheng¹, Heng Zhang¹, Dan Gao^1,*

Energy Engineering, Vol.119, No.6, pp. 2277-2296, 2022, DOI:10.32604/ee.2022.020795

Abstract

Nowadays, the zero liquid discharge of flue gas desulfurization (FGD) wastewater from coal-fired units has attracted the attention of all countries in the world. The pretreatment methods generally have the problems of high operation cost, small treatment capacity, and poor flexibility. However, the membrane method can avoid the above problems. In the current research, it has not been found that someone directly uses submerged ultrafiltration to pretreat FGD wastewater. Therefore, this paper innovatively proposed to directly use ceramic ultrafiltration membrane to treat FGD wastewater, which can ensure effluent quality and improve the flexibility of the pretreatment system. In this paper,… More >

HAIFENG WANG^1,2,*, JUAN GUO¹, TIEQIAO WEN^2,*

BIOCELL, Vol.46, No.12, pp. 2615-2624, 2022, DOI:10.32604/biocell.2022.021247

Abstract The characterization and functions of transmembrane protein 59-like (TMEM59L), a type I transmembrane protein, are not clearly understood until now. Some TMEM59L and fluorescent fusion proteins constructs were transfected in cell lines and liposomes, and their localization was observed. The effects of protein constructs were studied by fluorescence microscopy and western blotting. This study reports a novel function of human TMEM59L (hTMEM59L) related to the expression and location of some proteins. In addition, we report two novel splice variants of human TMEM59L (hTMEM59L). The localization of mutants of this protein, lacking a middle region, and a C-terminal deletion, markedly differed… More >

Jie Xu^*1, Zhongzhou Su^*1, Qiuping Ding^†, Liang Shen^*, Xiaohu Nie^*, Xuyan Pan^*, Ai Yan^*, Renfu Yan^*, Yue Zhou^*, Liqin Li^‡, Bin Lu^*

Oncology Research, Vol.27, No.7, pp. 819-826, 2019, DOI:10.3727/096504018X15478559215014

Abstract Human glioblastoma multiforme (GBM) accounts for the majority of human brain gliomas. Several TMEM proteins, such as TMEM 45A, TMEM 97, and TMEM 140, are implicated in human brain gliomas. However, the roles of TMEM168 in human GBM remain poorly understood. Herein we found that mRNA levels of TMEM168 were overexpressed in GBM patients (n=85) when compared with healthy people (n=10), which was also supported by data from The Cancer Genome Atlas (TCGA). Kaplan–Meier analysis of Gene Expression Omnibus dataset GSE16011 suggested that enhanced TMEM168 expression was associated with shorter survival time. To investigate whether and how TMEM168 functioned in… More >

Hongde Li^*†‡, Yueshuo Li^*†‡, Jianmin Hu^*†‡, Sufang Liu^§, Xiangjian Luo^*†‡¶, Min Tang^*†‡, Ann M. Bode^#, Zigang Dong^#**, Xinqi Liu^††, Weihua Liao^‡‡, Ya Cao^{*†‡¶ §§¶¶}

Oncology Research, Vol.28, No.7-8, pp. 763-778, 2020, DOI:10.3727/096504021X16135618512563

Abstract Epstein–Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) plays an important oncogenic role in the viral latent infection. Recently, increasing evidence indicates that the high expression of LMP1 during EBV lytic cycle is related to the viral lytic replication. However, the mechanism by which LMP1 regulates EBV lytic replication remains unclear. (−)-Epigallocatechin-3-gallate (EGCG) prevents carcinogenesis by directly targeting numerous membrane proteins and effectively inhibits EBV lytic cascade. Here, we demonstrated that LMP1 promotes EBV lytic replication through the downstream signal molecules MAPKs, including ERKs, p38, and JNKs. LMP1 induces the phosphorylation of p53 through MAPKs to enhance the ability of… More >

Heru Suryanto^1,2,*, Bili Darnanto Susilo³, Jibril Maulana³, Aminnudin³, Uun Yanuhar⁴, Surjani Wonorahardjo^2,5, Husni Wahyu Wijaya^2,5, Abu Saad Ansari⁶

Journal of Renewable Materials, Vol.10, No.9, pp. 2455-2465, 2022, DOI:10.32604/jrm.2022.020478

Abstract Waste is the main problem for the environment. Handling waste for various useful applications has a benefit for the future. This work has been studied for handling pineapple peel waste to make composite film bacterial cellulose nanocomposite membrane (BCNM) with addition graphite nanoplatelet (GNP). The concentration of GNP in the membrane influence the membrane properties. The bacterial cellulose (BC) pellicle was synthesized by using media from pineapple peel waste extract. BC pellicle is cleaned with water and NaOH solution to be free from impactors. BCNM is synthesized through the mechanical disintegration stage. The results of disintegration using high pressure homogenizer… More > Graphic Abstract

SHELDON R. GORDON^*

BIOCELL, Vol.46, No.9, pp. 2059-2063, 2022, DOI:10.32604/biocell.2022.019873

Abstract Much of our understanding of the events which underlie cell migration has been derived from studies of cells in tissue culture. One of the components that mediates this process is the dynamic actin-based microfilament system that can reorganize itself into so-called stress fibers that are considered essential components for cell motility. In contrast, relatively few studies have investigated cell movement along an extracellular matrix (ECM) which is known to influence both cellular organization and behavior. This opinion/viewpoint article briefly reviews cell migration during corneal endothelial wound repair along the tissue’s natural basement membrane, Descemet’s membrane. Because the tissue exists as… More >

JULIANA SOARES^1,2,#, DOUGLAS G. FREITAS^1,3,#, PEDRO S. LOURENÇO^1,4, JEFTE FARIAS^1,5, BRUNO PONTES^1,2,3,4,5,*

BIOCELL, Vol.46, No.9, pp. 2009-2013, 2022, DOI:10.32604/biocell.2022.019969

Abstract Mammalian cell surfaces consist of the plasma membrane supported by an underneath cortical cytoskeleton. Together, these structures can control not only the shape of cells but also a series of cellular functions ranging from migration and division to exocytosis, endocytosis and differentiation. Furthermore, the cell surface is capable of exerting and reacting to mechanical forces. Its viscoelastic properties, especially membrane tension and bending modulus, are fundamental parameters involved in these responses. This viewpoint summarizes our current knowledge on how to measure the viscoelastic properties of cell surfaces employing optical tweezers-based tether assays, paving the way for a better understanding of… More >