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  • Open Access

    REVIEW

    Mesenchymal stem cells and the angiogenic regulatory network with potential incorporation and modification for therapeutic development

    VAN THI TUONG NGUYEN1,2, KHUONG DUY PHAM1,2,3, HUONG THI QUE CAO1,2, PHUC VAN PHAM1,2,*

    BIOCELL, Vol.48, No.2, pp. 173-189, 2024, DOI:10.32604/biocell.2023.043664

    Abstract Mesenchymal stem cells (MSCs) have been proposed in regenerative medicine, especially for angiogenic purposes, due to their potential to self-renew, differentiate, and regulate the microenvironment. Peripheral vascular diseases, which are associated with reduced blood supply, have been treated but not cured. An effective therapy is to recover blood supply via vessel regeneration in the affected area, and MSCs appear to be promising for such conditions. Several studies aimed to explore the role of MSCs in performing angiogenesis and have revealed numerous potential methods to enhance MSC capacity in vessel formation. Efforts have been made to modify standard MSCs to optimize… More > Graphic Abstract

    Mesenchymal stem cells and the angiogenic regulatory network with potential incorporation and modification for therapeutic development

  • Open Access

    ARTICLE

    A Smart Obfuscation Approach to Protect Software in Cloud

    Lei Yu1, Yucong Duan2,*

    CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3949-3965, 2023, DOI:10.32604/cmc.2023.038970

    Abstract Cloud computing and edge computing brought more software, which also brought a new danger of malicious software attacks. Data synchronization mechanisms of software can further help reverse data modifications. Based on the mechanisms, attackers can cover themselves behind the network and modify data undetected. Related knowledge of software reverse engineering can be organized as rules to accelerate the attacks, when attackers intrude cloud server to access the source or binary codes. Therefore, we proposed a novel method to resist this kind of reverse engineering by breaking these rules. Our method is based on software obfuscations and encryptions to enhance the… More >

  • Open Access

    ARTICLE

    Novel defined N7-methylguanosine modification-related lncRNAs for predicting the prognosis of laryngeal squamous cell carcinoma

    ZHAOXU YAO*, HAIBIN MA, LIN LIU, QIAN ZHAO, LONGCHAO QIN, XUEYAN REN, CHUANJUN WU, KAILI SUN

    BIOCELL, Vol.47, No.9, pp. 1965-1975, 2023, DOI:10.32604/biocell.2023.030796

    Abstract Objective: Through integrated bioinformatics analysis, the goal of this work was to find new, characterised N7-methylguanosine modification-related long non-coding RNAs (m7G-lncRNAs) that might be used to predict the prognosis of laryngeal squamous cell carcinoma (LSCC). Methods: The clinical data and LSCC gene expression data for the current investigation were initially retrieved from the TCGA database & sanitised. Then, using co-expression analysis of m7G-associated mRNAs & lncRNAs & differential expression analysis (DEA) among LSCC & normal sample categories, we discovered lncRNAs that were connected to m7G. The prognosis prediction model was built for the training category using univariate & multivariate COX… More >

  • Open Access

    ARTICLE

    Elucidating the clinical and immunological value of m6A regulator-mediated methylation modification patterns in adrenocortical carcinoma

    WENHAO XU1,#, HAOMING LI2,#, YASIR HAMEED3, MOSTAFA A. ABDEL-MAKSOUD4, SAEEDAH MUSAED ALMUTAIRI4, AYMAN MUBARAK4, MOHAMMED AUFY5, WAEL ALTURAIKI6, ABDULAZIZ J. ALSHALANI6, AYMAN M. MAHMOUD7,*, CHEN LI8,*

    Oncology Research, Vol.31, No.5, pp. 819-831, 2023, DOI:10.32604/or.2023.029414

    Abstract N6-methyladenosine methylation (m6A) is a common type of epigenetic alteration that prominently affects the prognosis of tumor patients. However, it is unknown how the m6A regulator affects the tumor microenvironment (TME) cell infiltration in adrenocortical carcinoma (ACC) and how it affects the prognosis of ACC patients yet. The m6A alteration patterns of 112 ACC patients were evaluated, furthermore, the association with immune infiltration cell features was investigated. The unsupervised clustering method was applied to typify the m6A alteration patterns of ACC patients. The principal component analysis (PCA) technique was taken to create the m6A score to assess the alteration pattern… More >

  • Open Access

    ARTICLE

    High-Imperceptibility Data Hiding Scheme for JPEG Images Based on Direction Modification

    Li Liu1, Jing Li1, Yingchun Wu1, Chin-Chen Chang2,*, Anhong Wang1

    Computer Systems Science and Engineering, Vol.47, No.2, pp. 1415-1432, 2023, DOI:10.32604/csse.2023.040039

    Abstract Data hiding (DH) is an important technology for securely transmitting secret data in networks, and has increasing become a research hotspot throughout the world. However, for Joint photographic experts group (JPEG) images, it is difficult to balance the contradiction among embedded capacity, visual quality and the file size increment in existing data hiding schemes. Thus, to deal with this problem, a high-imperceptibility data hiding for JPEG images is proposed based on direction modification. First, this proposed scheme sorts all of the quantized discrete cosine transform (DCT) block in ascending order according to the number of non-consecutive-zero alternating current (AC) coefficients.… More >

  • Open Access

    ARTICLE

    Surfactant-Modified Hydrophobic Biochar Derived from Laver (Porphyra haitanensis) with Superior Removal Performance for Kitchen Oil

    Jiaxing Sun1, Lili Ji1,*, Qianrui He1, Ran Li1, Xiaoyue Xia2, Yaning Wang1, Yi Yang2, Lu Cai3, Jian Guo2

    Journal of Renewable Materials, Vol.11, No.8, pp. 3227-3243, 2023, DOI:10.32604/jrm.2023.027160

    Abstract

    In this study, a novel absorpent (MSAR600°C) with a hydrophobic surface and hierarchical porous structure for the removal of kitchen oil was facilely fabricated from the macroalgae, laver (Porphyra haitanensis) by incorporating high-temperature carbonization and alkyl polyglucosides (APG) and rhamnolipid (RL) surfactants modification. The characterization results showed MSAR600°C possessed a louts-leaf-like papillae microstructure with high contact angle (137.5°), abundant porous structure with high specific surface area (23.4 m2/g), and various oxygen-containing functional groups (-OH, C=O, C-O). Batch adsorption experiments were conducted to investigate the effect of adsorption time, temperature, pH, and absorbent dose on kitchen oil adsorption performance. Then the… More > Graphic Abstract

    Surfactant-Modified Hydrophobic Biochar Derived from Laver (<i>Porphyra haitanensis</i>) with Superior Removal Performance for Kitchen Oil

  • Open Access

    ARTICLE

    Plasticizing Effect of Camellia oleifera Seed-Oil-Based Plasticizer on PVC Material Modification

    Qinghua Lao1,#, Hui Zhang1,#, Zhihong Wang2, Puyou Jia3, Yongquan Li1,*, Qiaoguang Li4,*

    Journal of Renewable Materials, Vol.11, No.7, pp. 3025-3041, 2023, DOI:10.32604/jrm.2023.026646

    Abstract In this study, as the plasticizer, Camellia oleifera seed-oil-based cyclohexyl ester (COSOCE) was prepared by the reaction of cyclohexene oxide and refined C. oleifera seed oil (RCOSO) obtained by acidification hydrolysis after saponification. In addition, the structure of the target product was confirmed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR) spectroscopy, and Raman spectroscopy. COSOCE was used as plasticizer-modified polyvinyl chloride (PVC) membranes. The structure of the COSOCE-modified PVC membranes were characterized by Raman spectroscopy and scanning electron microscopy (SEM). The properties of the COSOCE-modified PVC membrane were characterized by contact angle measurements, universal testing machine, thermogravimetric… More >

  • Open Access

    ARTICLE

    Carbon Capture from Flue Gas Based on the Combination of Non-Contact Hydrophobic Porous Ceramic Membrane and Bubbling Absorption

    Yongde Luo, Jiang Jin*, Hua Zhang*

    Journal of Renewable Materials, Vol.11, No.7, pp. 3143-3153, 2023, DOI:10.32604/jrm.2023.027396

    Abstract A hybrid system combined with a non-contact membrane and bubbling absorption is proposed to capture CO2 from flue gas. The non-contact way of membrane and liquid absorbent effectively avoids the reduction of gas diffusion flux through the membrane. High-porosity ceramic membranes in hybrid systems are used for gas-solid separation in fuel gas treatment. Due to the high content of H2O and cement dust in the flue gas of the cement plant, the membrane is hydrophobically modified by polytetrafluoroethylene (PTFE) to improve its anti-water, anti-fouling, and self-cleaning performances. The results show that the diffusion flux of CO2 through the membrane is… More >

  • Open Access

    ARTICLE

    MODIFICATION OF PERFORATED PLATE IN FLUIDIZED-BED COMBUSTOR TO PROVIDE SUFFICIENT AIR SUPPLY IN THE COMBUSTION

    Erdiwansyah Erdiwansyaha,d , Mahidin Mahidinb, Husni Husinb, Muhammad Faisalc, Usman Usmanc, Muhtadin Muhtadinc, Asri Ganib,*, Rizalman Mamate

    Frontiers in Heat and Mass Transfer, Vol.18, pp. 1-6, 2022, DOI:10.5098/hmt.18.25

    Abstract The modification of the perforated plate applied in this study aims to provide sufficient air access into the combustion chamber. Burning experiments were carried out with three different types of fuel (such as palm kernel shell (PKS), oil palm midrib (OPM), and empty fruit bunches (EFB). The purpose of the experiment with the modification of the perforated plate is to investigate the combustion temperature and the rate of heat transfer in the boiler. The fluidized-bed combustor (FBC) combustion chamber is used as the combustion chamber. Experimental results were obtained at four different points using a Digital Thermometer with a thermocouple.… More >

  • Open Access

    ARTICLE

    Weak Expansive Soil Physical Properties Modification by Means of a Cement-Jute Fiber

    Zisheng Yang1, Wendong Li1, Xuelei Cheng1,2,*, Ran Hai1, Shunqun Li3

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.8, pp. 2119-2130, 2023, DOI:10.32604/fdmp.2023.025444

    Abstract Sixteen groups of comprehensive tests have been conducted to investigate the modifications in the physical properties of a weak expansive soil due to the addition of a cement jute fiber. The tests have been conducted to analyze the liquid plastic limit, the particle distribution and the free expansion rate. The results show that: (1) With an increase in the cement-jute fiber content, the free expansion rate of the modified expansive soil gradually decreases, however, such a rate rebounds when the fiber content exceeds 0.5% and the cement content exceeds 6%. (2) With an increase in the cement percentage, the particle… More >

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