Adel Arezki^1,*, Iman Sadri^1,*, Ahmed S. Zakaria², Felix Couture³, David-Dan Nguyen⁴, Pierre Karakiewicz⁵, Dean S. Elterman⁶, Kevin C. Zorn²

Canadian Journal of Urology, Vol.30, No.1, pp. 11424-11431, 2023

Abstract Introduction: This study aims to report age-stratified potency outcomes in men undergoing robot-assisted radical prostatectomy (RARP).
Materials and methods: A retrospective review was performed on a database of 1737 patients who underwent RARP for localized prostate cancer between 2007 and 2019. Inclusion criteria consisted of patients undergoing bilateral nerve-sparing RARP. Exclusion criteria were preoperative Sexual Health Inventory for Men (SHIM) score < 17 and postoperative androgen deprivation therapy or radiotherapy. Patients were divided into four cohorts based on age: ≤ 54 years (group 1); 55-59 years (group 2); 60-64 years (group 3) and ≥ 65 years (group… More >

Alexis E. Te¹, Christina Sze¹, Steven A. Kaplan², Bilal Chughtai¹

Canadian Journal of Urology, Vol.30, No.1, pp. 11408-11413, 2023

Abstract Introduction: A common indication for benign prostate hyperplasia (BPH) therapies is failure to improve with medical therapy. However, pivotal Federal Drug Administration (FDA) registered randomized clinical trials (RCTs) for minimally invasive surgical therapies (MISTs) are designed to be compared to either sham or placebo while off medical therapy at baseline, and as an alternative to medical therapy. There are few if any RCTs reporting the MISTS efficacy in patients with true medical therapy failure. We report on the efficacy of robotic water jet ablation therapy (RWT) and TURP in patients who have failed to improve with… More >

Devon M. Langston¹, Daniel Evans², Stanley Moore³, Jolie Shen³, Ziho Lee⁴, Jonathan Wingate⁴, Alexander J. Skokan⁴, Aron Liaw⁵, Judith C. Hagedorn³, Benjamin N. Breyer⁵, Nima Baradaran²

Canadian Journal of Urology, Vol.30, No.2, pp. 11487-11494, 2023

Abstract Introduction: Fournier’s gangrene (FG), is a progressive, necrotizing soft tissue infection of the external genitalia, perineum, and/or anorectal region. How treatment and recovery from FG impacts quality of life related to sexual and general health is poorly characterized. Our purpose is to evaluate the long term impact of FG on overall and sexual quality of life using standardized questionnaires through a multi-institutional observational study.
Materials and methods: Multi-institutional retrospective data were collected by standardized questionnaires on patient-reported outcome measures including the Changes in Sexual Functioning Questionnaire (CSFQ) and the Veterans RAND 36 (VR-36) survey of general health-related… More >

Tawfik Elsherbini^1,*, David Bouhadana^2,*, Iman Sadri³, David-Dan Nguyen⁴, Kyle W. Law⁵, Adel Arezki³, Claudia Deyirmendjian¹, Ahmed Ibrahim⁵, Naeem Bhojani⁵, Dean S. Elterman⁶, Bilal Chughtai⁷, Franck Bruyère⁸, Luca Cindolo⁹, Giovanni Ferrari⁹, Carlos Vasquez-Lastra¹⁰, Tiago Borelli-Bovo¹¹, Edgardo F. Becher¹², Hannes Cash¹³, Maximillian Reimann¹⁴, Enrique Rijo¹⁵, Vincent Misrai¹⁶, Kevin C. Zorn⁵

Canadian Journal of Urology, Vol.30, No.2, pp. 11473-11479, 2023

Abstract Introduction: In this study, we sought to investigate the impact of 5-alpha reductase inhibitors (5-ARI) on the perioperative and functional outcomes of 180-Watt XPS GreenLight photovaporization of the prostate (PVP) using a large international database.
Materials and methods: Data were obtained from the Global GreenLight Group (GGG) database, which includes eight high-volume, experienced surgeons from seven international centers. All men with established benign prostatic hyperplasia (BPH) with known 5-ARI status who underwent GreenLight PVP using the XPS-180W system between 2011 and 2019 were eligible for the study. Patients were assigned to two groups based on the preoperative… More >

Christopher J. Staniorski¹, Mitchell B. Alameddine¹, Shyam Patnaik¹, Michelle J. Semins²

Canadian Journal of Urology, Vol.30, No.5, pp. 11692-11697, 2023

Abstract Introduction: Proper antegrade access for percutaneous nephrolithotomy (PCNL) is essential for success but can be challenging. Previous work evaluating access obtained by interventional radiology (IR), largely in the emergent setting, has shown high rates of additional access at the time of PCNL. We hypothesize that efforts to improve pre-procedural communication between urology and IR can impact the utility of the access for subsequent PCNL.
Material and methods: We conducted a retrospective review of patients undergoing PCNL at a single hospital from January 2011 to December 2022. Adult patients undergoing PCNL with established preoperative access were included.
Results: A… More >

Kussil Oumedjbeur¹, Nicholas J. Corsi², David Bouhadana³, Ahmed Ibrahim⁴, David-Dan Nguyen⁵, Imad Matta⁴, Adel Arezki³, Iman Sadri³, Tawfik Elsherbini⁶, Naeem Bhojani⁴, Dean S. Elterman⁵, Bilal Chughtai⁷, Brian T. Helfand⁸, Alexander P. Glaser⁸, Vincent Misrai⁹, Steven Kaplan¹⁰, Peter Gilling¹¹, Neil Barber¹², Mihir Desai¹³, Gopal H. Badlani¹⁴, Alexis E. Te⁷, Claus G. Roehrborn¹⁵, Kevin C. Zorn⁴

Canadian Journal of Urology, Vol.30, No.5, pp. 11650-11658, 2023

Abstract Introduction: To report the 5-year efficacy and safety of Aquablation compared with transurethral resection of the prostate for the management of lower urinary tract symptoms secondary to benign prostatic hyperplasia in men with prostate volumes 50-80 mL.
Materials and methods: In a large double-blinded, multicenter, and prospective randomized controlled trial, 96 randomized men with 50-80 mL prostates who underwent Aquablation or transurethral prostate resection were prospectively identified for subgroup analysis. Follow up was performed for up to 5 years. The primary efficacy endpoint was the reduction in International Prostate Symptom Score (IPSS) at 6 months. The primary… More >

Yulan Yu^1,2, Rassamee Chotipanvithayakul³, Hujiao Kuang⁴, Wit Wichaidit^3,*, Chonghua Wan^1,2,*

International Journal of Mental Health Promotion, Vol.25, No.12, pp. 1343-1351, 2023, DOI:10.32604/ijmhp.2023.043446 - 29 December 2023

Abstract Adverse childhood experiences (ACEs) can negatively affect mental health, whereas character strengths seem to be positively correlated with mental health. Detailed information on the history of ACEs among university students in China and the extent which mental health is associated with ACEs and character strengths can contribute to the needed empirical evidence for relevant stakeholders. Objectives of this study are 1) to estimate the prevalence of ACEs among undergraduate students in Southern China; and 2) to assess the extent which mental health outcomes (positive growth, well-being, and depression) are associated with ACEs and character strengths… More >

SUKHENDU DEY^1,#, SANDIPAN PAL^2,#, APURBA RATAN GHOSH¹, PALAS SAMANTA^3,*

BIOCELL, Vol.47, No.12, pp. 2579-2590, 2023, DOI:10.32604/biocell.2023.031114 - 27 December 2023

Abstract The process of development is intricate and couple-dependent phenomenon. Accordingly, the study of molecular and cellular biology-based developmental toxicology biomarkers increasingly is becoming an important part of risk assessment and management of chemicals for detection of health outcomes and/or biological endpoint like cytotoxicity, cell death, etc. Since, the evolution of developmental toxicology field a number of tools/markers have been developed or addressed to deal with developmental outcomes, which can ultimately be used for the development of adverse outcome pathways (AOPs) of developmental toxicants. As a result, this paper provides an overview of the current state… More >

François-Xavier Van Vyve¹, Karlien Carbonez², Jelena Hubrechts², Geoffroy de Beco¹, Jean E. Rubay¹, Mona Momeni³, Thierry Detaille⁴, Alain J. Poncelet^1,*

Congenital Heart Disease, Vol.18, No.5, pp. 539-550, 2023, DOI:10.32604/chd.2023.042344 - 10 November 2023

Abstract Objectives: Over the last decade, neonatal repair has been advocated for many congenital heart diseases. However, specific subgroups of complex congenital heart disease still require temporary palliation for which both surgical and endovascular techniques are currently available. We reviewed our institutional experience with shunt palliation with an emphasis on risk factors for early mortality. Methods: This is a single-center retrospective study on 175 patients undergoing surgery for central shunt or modified Blalock-Taussig shunt. All data were extracted from a prospectively collected computerized database. We identified risk factors for early mortality by uni- and multi-variable analysis.… More >

François-Xavier Van Vyve^1,#, Karlien Carbonez^2,#, Geoffroy de Beco¹, Stéphane Moniotte², Jean E. Rubay¹, Mona Momeni³, Laurent Houtekie⁴, Alain J. Poncelet^1,*

Congenital Heart Disease, Vol.18, No.5, pp. 525-537, 2023, DOI:10.32604/chd.2023.042341 - 10 November 2023

Abstract Objective: Despite increasing enthusiasm for neonatal repair, patients with ductal-dependent circulation (pulmonary/systemic) or restrictive pulmonary blood flow still require initial palliation. Ductal stenting has emerged as an endovascular approach whereas modified-Blalock-Taussig and central shunt remain surgical references. In this study, we analyzed the relationship between pulmonary artery growth, sites of shunt connection, or antegrade pulmonary blood flow in surgically placed shunts. The need for secondary catheter-based interventions or pulmonary arterioplasty was also investigated. Methods: A retrospective single-center study analyzing 175 patients undergoing surgery for a central or modified-Blalock-Taussig shunt. Outcome growth variables were right pulmonary… More > Graphic Abstract