Yousef Asiri^*

Computer Systems Science and Engineering, Vol.41, No.1, pp. 35-50, 2022, DOI:10.32604/csse.2022.020100

Abstract Most of the international accreditation bodies in engineering education (e.g., ABET) and outcome-based educational systems have based their assessments on learning outcomes and program educational objectives. However, mapping program educational objectives (PEOs) to student outcomes (SOs) is a challenging and time-consuming task, especially for a new program which is applying for ABET-EAC (American Board for Engineering and Technology the American Board for Engineering and Technology—Engineering Accreditation Commission) accreditation. In addition, ABET needs to automatically ensure that the mapping (classification) is reasonable and correct. The classification also plays a vital role in the assessment of students’ learning. Since the PEOs are… More >

Jadranka Separovic Hanzevacki¹, Marija Brestovac^1,*, Vlatka Reskovic Luksic¹, Blanka Glavas Konja¹, Martina Lovric Bencic¹, Josko Bulum¹, Darko Anic²

Congenital Heart Disease, Vol.16, No.5, pp. 469-475, 2021, DOI:10.32604/CHD.2021.015237

Abstract Patients with complete transposition of the great arteries (TGA) treated by the Senning procedure have a higher risk of developing heart failure due to: a) additional work load of the systemic (morphologic right) ventricle (sRV), b) arrhythmias, mainly caused by surgical implications at the atria as well as c) worsening of systemic tricuspid regurgitation. We present a unique case of a female patient who developed all these complications, who was successfully treated and was able to carry out a twin pregnancy. This breakthrough approach was based on: 1. detecting reversibility potential of myocardial systolic dysfunction in a severe valvular lesion… More >

Caili Li¹, Dalin Tang^2,*,3, Jing Yao^4,*, Christopher Baird⁵, Haoliang Sun⁶, Chanjuan Gong⁷, Luyao Ma⁶, Yanjuan Zhang⁴, Liang Wang², Han Yu², Chun Yang⁸, Yongfeng Shao⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.127, No.1, pp. 159-174, 2021, DOI:10.32604/cmes.2021.014580

Abstract Aortic valve replacement (AVR) remains a major treatment option for patients with severe aortic valve disease. Clinical outcome of AVR is strongly dependent on implanted prosthetic valve size. Fluid-structure interaction (FSI) aortic root models were constructed to investigate the effect of valve size on hemodynamics of the implanted bioprosthetic valve and optimize the outcome of AVR surgery. FSI models with 4 sizes of bioprosthetic valves (19 (No. 19), 21 (No. 21), 23 (No. 23) and 25 mm (No. 25)) were constructed. Left ventricle outflow track flow data from one patient was collected and used as model flow conditions. Anisotropic Mooney–Rivlin… More >

Reghan Conrey^1,*, Sebastian Tume², Carlos Bonilla-Ramirez³, Seema Lalani⁴, Dean McKenzie^3,#, Marc Anders^2,#

Congenital Heart Disease, Vol.16, No.2, pp. 171-181, 2021, DOI:10.32604/CHD.2021.014409

Abstract Background: Patients with genetic syndromes who undergo surgery to correct congenital heart defects can be at risk for increased morbidity or mortality. Surgical outcomes and postoperative courses following congenital heart surgery in patients with Kabuki-Syndrome (KS) have not been well studied. Objectives: The purpose of this study was to describe the postoperative courses and associated outcomes in the largest set of KS patients undergoing congenital heart surgery to date. Methods: Patients with a confirmed molecular diagnosis of KS and a diagnosis of a CHD admitted to Texas Children’s Hospital between January 1, 2000 and January 1, 2020 were included (n… More >

Waleed Rashideh^1,*, Omar Abdullah Alshathry¹, Samer Atawneh², Hussein Al Bazar³, Mohammed Said AbualRub⁴

Intelligent Automation & Soft Computing, Vol.26, No.6, pp. 1285-1307, 2020, DOI:10.32604/iasc.2020.012995

Abstract Scientific programs in higher educational institutes are measured by their performances in showing evidences for expected quality assurance levels and for obtaining the academic accreditation. However, obtaining an accreditation for a scientific program is a lengthy process, as it requires extensive efforts from all members belonging to the program. The Accreditation Board for Engineering and Technology (ABET) accreditation is a common form of quality assurance that is based on different areas such as computing, engineering and sciences. In order to determine the ABET accreditation, several processes and methods are assessed to guarantee the required accreditation. Similar to many other programs,… More >

WENXI GAO^1,2,#, QIANQIAN MA^3,#, CHENYU TANG^2,#, YUELI ZHAN⁴, YINONG DUAN², HUIHUA NI^5,*, YUNZHAO XU^5,6,*

BIOCELL, Vol.44, No.4, pp. 597-605, 2020, DOI:10.32604/biocell.2020.011328

Abstract Cervical cancer (CESC) is one of the most common cancers and affects the female genital tract. Consistent HPV infection status has been determined to be a vital cause of tumorigenesis. HPV infection may induce changes to the immune system and limit the host’s immune response. Immunotherapy is therefore essential to improving the overall survival of both locally advanced and recurrent CESC patients. Using 304 relevant samples from TCGA, we assessed immune cell function in CESC patients to better understand the status of both tumor micro-environment cells and immune cells in CESC. Functional enrichment analysis, pathway enrichment analysis, and PPI network… More >

Claudia Herbst^1,*, Haibo Zhang², Renjie Hu², Jürgen Hörer³, Masamichi Ono³, Vladimiro Vida⁴, Tjark Ebels^5,6, Andrzej Kansy⁷, Jeffrey P. Jacobs⁸, Zdzislaw Tobota⁷, Bohdan Maruszewski⁷

Congenital Heart Disease, Vol.16, No.1, pp. 17-25, 2021, DOI:10.32604/CHD.2021.012982

Abstract Background: The European Congenital Heart Surgeons Association (ECHSA) Congenital Heart Surgery Database (CHSD) was founded in 1999 and is open for worldwide participation. The current dataset includes a large amount of surgical data from both Europe and China. The purpose of this analysis is to compare patterns of practice and outcomes among pediatric congenital heart defect surgeries in Europe and China using the ECHSA-CHSD. Methods: We examined all European (125 centers, 58,261 operations) and Chinese (13 centers, 23,920 operations) data in the ECHSA-CHSD from 2006-2018. Operative mortality, postoperative length of stay, median patient age and weight were calculated for the… More >

Jiachen Li, Xianchao Jiang, Sim-eng Zhang, Jinyang Liu, Yajuan Zhang, Jun Yan, Shoujun Li, Qiang Wang^*

Congenital Heart Disease, Vol.15, No.5, pp. 387-397, 2020, DOI:10.32604/CHD.2020.013127

Abstract Background: Ebstein’s anomaly (EA) is a malformation of the tricuspid valve (TV) and myopathy of the right ventricle (RV). Surgery is now the main treatment for the defect. Objective: To summarize our surgical results and experience based on patients with EA who were under 7 years of age and treated with different surgical treatments. Design: Single-center cohort study of Ebstein’s anomaly. Setting: China. Participants: 80 patients under 7 years old who were diagnosed of EA and underwent different surgical treatments were consecutively enrolled in our research from January 2010 to December 2019. Results: The median age of the 80 patients… More >

Francisco Javier Ruperti-Repilado^1,#,*, Magalie Ladouceur^2,#, Pastora Gallego³, Laura Dos⁴, Joaquin Rueda Soriano⁵, Berto Bouma⁶, Harald Gabriel⁷, Markus Schwerzmann¹, Judith Bouchardy^8,9, Daniel Tobler^10,#, Matthias Greutmann^11,#

Congenital Heart Disease, Vol.15, No.5, pp. 309-338, 2020, DOI:10.32604/CHD.2020.012599

Abstract Background: Long-term outcomes in adults with prior arterial switch operation (ASO) have not yet been well defined. The aim of this study is to elucidate incidence and predictors of adverse cardiac outcomes in a prospectively followed cohort of adults after their ASO. Methods: The comprehensive longterm follow up of adults with ASO is a project within the European collaboration for prospective outcome research in congenital heart disease (EPOCH). It is designed as a prospective, international multicenter cohort study. Consecutive patients (age ≥ 16 years) with prior ASO will be included at 11 European tertiary care centers. Participants will be followed… More >

Shengwen Guo, Yuanyuan Tong, Liting Bai, Peiyao Zhang, Xin Duan^*, Jinping Liu^*

Congenital Heart Disease, Vol.15, No.5, pp. 275-285, 2020, DOI:10.32604/CHD.2020.011894

Abstract Objective: Serum ferritin has been identified as a prognostic marker in patients with a variety of diseases. In the present study we aim to determine the prevalence of risk factors and outcomes for hyperferritinemia in children undergoing cardiac surgery with cardiopulmonary bypass for congenital heart defects. Methods: The serum ferritin levels of 457 children between the ages of twentyeight days and three years undergoing cardiopulmonary bypass surgery between June 1, 2017 and June 1, 2018 were analyzed. The prevalence of early postoperative hyperferritinemia was investigated; hyperferritinemia was defined as a ferritin level ≥250 ng/ml. Multivariable regression models including candidate risk… More >