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  • Open Access

    ARTICLE

    Low molecular weight heparin as an anticoagulation strategy for left-sided ablation procedures

    Karen Hinsley, Margaret Evans-Langhorst, Courtney Porter, Stephanie Chandler, Christina VanderPluym, John Triedman, Vassilios J. Bezzerides

    Congenital Heart Disease, Vol.13, No.2, pp. 222-225, 2018, DOI:10.1111/chd.12551

    Abstract Objective: This quality improvement study was implemented to demonstrate consistent and reliable post procedure anticoagulation for patients undergoing left-sided ablations. We evaluated the safety and efficacy of anticoagulation practice during a transition from anticoagulation with overnight infusion of unfractionated heparin to a single subcutaneous injection of low molecular weight heparin.
    Methods: Outcomes for patients who received unfractionated heparin from January 2014 to October 2014, were compared with outcomes of patients who received low molecular weight heparin from October 2014 to October 2015. Complications prepractice and postpractice change were documented and compared to establish confidence in the practice change and confirm… More >

  • Open Access

    ARTICLE

    Arrhythmia after cone repair for Ebstein anomaly: The Mayo Clinic experience in 143 young patients

    Philip Wackel1,2, Bryan Cannon1,2, Joseph Dearani3, Kristen Sessions1,2, Kimberly Holst3, Jonathan Johnson1,2, Frank Cetta1,2

    Congenital Heart Disease, Vol.13, No.1, pp. 26-30, 2018, DOI:10.1111/chd.12566

    Abstract Background: The increased incidence of preoperative and postoperative arrhythmia in Ebstein anomaly (EA) prompted some clinicians to perform an electrophysiology study (EPS) in all patients prior to surgery for EA. The cone repair (CR) is the current surgical option of choice for most young patients with EA but the effect of the CR on arrhythmia is not well established.
    Objectives: To assess the burden of arrhythmia in young patients after CR and to assess the utility of selective preoperative EPS.
    Materials and Methods: A retrospective review of all patients <21 years of age with EA who had a CR at… More >

  • Open Access

    ARTICLE

    Parenting stress trajectories during infancy in infants with congenital heart disease: Comparison of single‐ventricle and biventricular heart physiology

    Nadya Golfenshtein1, Alexandra L. Hanlon2, Janet A. Deatrick3, Barbara Medoff‐Cooper3,4

    Congenital Heart Disease, Vol.14, No.6, pp. 1113-1122, 2019, DOI:10.1111/chd.12858

    Abstract Objective: Parents of infants with congenital heart disease (CHD) experience increased parenting stress levels, potentially interfering with parenting practices and bear adverse family outcomes. Condition severity has been linked to parenting stress. The current study aimed to explore parenting stress trajectories over infancy in parents of infants with complex CHD, and to compare them by post‐operative cardiac physiology.
    Design: Data from a larger prospective cohort study was analyzed using longitudinal mixed‐effects regression modeling.
    Setting: Cardiac intensive care unit and outpatient clinic of a 480‐bed children's hospital in the American North‐Atlantic region.
    Participants: Parents of infants with complex CHD (n =… More >

  • Open Access

    Feeding methods for infants with single ventricle physiology are associated with length of stay during stage 2 surgery hospitalization

    Jeannine M. Hoch1, Oluwatosin Fatusin2, Gayane Yenokyan3, W. Reid Thompson2, Maureen A. Lefton‐Greif4

    Congenital Heart Disease, Vol.14, No.3, pp. 438-445, 2019, DOI:10.1111/chd.12742

    Abstract Background: Tube feedings are often needed to achieve the growth and nutrition goals associated with decreased morbidity and mortality in patients with single ventricle anat‐ omy. Variability in feeding method through the interstage period has been previously described, however, comparable information following stage 2 palliation is lacking.
    Objectives: To identify types of feeding methods following stage 2 palliation and their influence on length of stay.
    Design: Secondary analysis of the National Pediatric Cardiology Quality Improvement Collaborative registry was performed on 932 patients. Demographic data, medical characteristics, postoperative complications, type of feeding method, and length of stay for stage 2 palliation… More >

  • Open Access

    ARTICLE

    Focal liver lesions following Fontan palliation of single ventricle physiology: A radiology‐pathology case series

    Emily M. Engelhardt1, Andrew T. Trout2,3, Rachel M. Sheridan4, Gruschen R. Veldtman5, Jonathan R. Dillman2,3

    Congenital Heart Disease, Vol.14, No.3, pp. 380-388, 2019, DOI:10.1111/chd.12730

    Abstract Purpose: Patients who have undergone Fontan palliation of single ventricle physiol‐ ogy congenital heart disease are prone to developing focal liver lesions. In our experi‐ ence, the variety of lesions occurring in this population is greater than that described in the literature. The purpose of this study was to describe the breadth of biopsy‐ proven liver lesions in patients post–Fontan palliation of single ventricle physiology cared for at our institution.
    Methods: We retrospectively identified patients who had previously undergone the Fontan operation and had a focal liver lesion biopsied between January 2000 and June 2018. Medical records were reviewed for… More >

  • Open Access

    ARTICLE

    Production system and value chain in oregano (Origanum sp.) cultivation in the province of Córdoba (Argentina)

    Argüello JA1, SB Núñez1, V Davidenco1, DA Suárez2, L Seisdedos1, MC Baigorria1, N La Porta1, G Ruiz1, V Yossen1

    Phyton-International Journal of Experimental Botany, Vol.81, pp. 23-34, 2012, DOI:10.32604/phyton.2012.81.023

    Abstract The aim of the present review was to analyze and identify the problems associated with the Production System and Chain Value of Oregano in the area of Traslasierra Valley, province of Córdoba. Traditional ecotypes, such as Criollo, Chileno II and Compacto, are cultivated in the region, as well as new ecotypes such as “Serrano Cordobés”, “Flor Rosa” and “Rosa Fuerte”. The Traslasierra Valley of Córdoba is a very suitable area for the production and for increasing the production of oregano. However, the agricultural management of the different oregano ecotypes should be optimized. Ecophysiological studies conducted to date in the region… More >

  • Open Access

    ARTICLE

    Adverse effects induced by chromium VI, cadmium and arsenic exposure on hypothalamus-pituitary physiology

    Jimena P. CABILLA, Sonia A. RONCHETTI, Beatriz H. DUVILANSKI*

    BIOCELL, Vol.40, No.1, pp. 15-18, 2016, DOI:10.32604/biocell.2016.40.015

    Abstract Environmental contamination with some metalloids and heavy metals (M/HM) raises concern due to well known adverse effects on health. Among these pollutants, chromium VI (Cr VI), cadmium (Cd) and arsenic (As) are frequently present as a result of natural sources or due to industrial activities. They are able to easily enter the organism and negatively affect many organs and systems. In vivo (exposure to Cr VI, Cd or As through drinking water) and in vitro experiments (primary pituitary cell cultures) were performed in male Wistar rats to address their actions on hypothalamus-pituitary axis. All the M/HM accumulated in hypothalamus and… More >

  • Open Access

    ARTICLE

    Effects of Melatonin on Growth, Physiology and Gene Expression in Rice Seedlings Under Cadmium Stress

    Xiachen Lv1,#, Yunxia Fang1,#, Lantian Zhang1, Weiyi Zhang1, Ling Xu1, Jingjin Han1, Bailing Jin2, Xian Zhang1, Xiaoqin Zhang1,*, Dawei Xue1,*

    Phyton-International Journal of Experimental Botany, Vol.88, No.2, pp. 91-100, 2019, DOI:10.32604/phyton.2019.06622

    Abstract Melatonin (MLT) is a hormonal substance found in many organisms and can improve plant stress resistance. In this study, the japonica rice variety Y32 and indica rice variety NJ6 were cultivated in hydroponics under different concentrations of CdCl2 at the two-leaf stage. The growth, physiological and biochemical responses of the seedlings and the expression of cadmium (Cd)-related genes under exogenous melatonin (MLT) treatment were assessed. The results indicated that Cd stress destroyed the dynamic balance between reactive oxygen species (ROS) production and removal, resulting in ROS accumulation, membrane lipid peroxidation, and impaired growth and development. Following the application of exogenous… More >

  • Open Access

    ABSTRACT

    Establishment of the Realistic Breathing Patterns in Different Exercise Conditions by Experimental Measurement

    chun-chi Li1, chin-chiang Wang2, yin-chia Su2, yu-chen Chu2, chia-chu Weng2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.11, No.2, pp. 31-32, 2009, DOI:10.3970/icces.2009.011.031

    Abstract The aim of this paper was to establish the realistic breathing patterns in different exercise conditions by experimental measurement. Generally, the human inhalation rate varies from 15 L/min at rest to 135 L/min for intense exercise and the breathing cycles are varied with different exercise conditions. Previous author have used symmetric Weibel configuration to establish three realistic breathing patterns, i. e., resting (inhalation rate, 15 L/min), light activity (inhalation rate, 30 L/min), and moderate exercise (inhalation rate, 60 L/min). In this study, in addition to reconstructing the three realistic breathing patterns of above mention, we expand the establishment of the… More >

  • Open Access

    REVIEW

    Pathophysiology of Glaucoma and Continuous Measurements of Intraocular Pressure

    Arthur J. Sit*, John H.K. Liu

    Molecular & Cellular Biomechanics, Vol.6, No.1, pp. 57-70, 2009, DOI:10.3970/mcb.2009.006.057

    Abstract Glaucoma is a leading cause of visual impairment and blindness worldwide. The main risk factor for glaucoma is an elevated intraocular pressure (IOP), which is also the only currently treatable risk factor. Despite its importance, our understanding of IOP is incomplete and our ability to measure IOP is limited. IOP is known to undergo both random fluctuations as well as variations following a circadian pattern. In humans, IOP is highest at night and lower during the daytime, largely due to changes in body position, although other factors appear to contribute. In rabbits, IOP is also highest at night and lower… More >

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