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  • Open Access

    ARTICLE

    An Adaptive Trajectory-Assisted Dynamic Indoor Positioning Method Based on RSS Fingerprinting

    Jing Liu1,2, Weijie Tan1,2,3,*

    CMC-Computers, Materials & Continua, Vol.88, No.3, 2026, DOI:10.32604/cmc.2026.083401 - 23 July 2026

    Abstract Due to its low hardware cost and ease of deployment, WiFi fingerprinting has become a prominent research direction in indoor positioning. However, traditional methods based on Received Signal Strength (RSS) still face three critical challenges: susceptibility to noise interference, low retrieval efficiency as fingerprint databases scale up, and trajectory instability in dynamic environments. These challenges are inherently rooted in the stochastic fluctuation of RSS signals, the high-dimensional and non-Euclidean nature of fingerprint space, and the unpredictability of user movement patterns. To address these limitations, an adaptive trajectory-assisted dynamic indoor positioning algorithm based on RSS fingerprinting,… More >

  • Open Access

    ARTICLE

    A Deep Learning Approach to Pedestrian Dead Reckoning: Accounting for Latent Variables with Deep Belief Networks

    Kyeonghyun Yoo#, Sangmin Lee#, Hwangnam Kim*

    CMC-Computers, Materials & Continua, Vol.88, No.3, 2026, DOI:10.32604/cmc.2026.082726 - 23 July 2026

    Abstract Inertial Measurement Unit (IMU)-based Pedestrian Dead Reckoning (PDR) enables infrastructure-free indoor positioning and requires heading-drift compensation associated with gyroscope bias. This paper proposes a stationary-window-based Deep Belief Network (DBN) framework that learns a gyroscope bias representation from z-axis angular-velocity and sampling-interval sequences observed during stationary intervals and applies it to heading correction during walking. The learned representation captures the residual angular-velocity offset under stationary conditions and serves as an adaptive correction term for subsequent heading integration. Experiments on short-term, three-lap long-term, and complex indoor paths show that stationary-window-based DBN bias estimation is particularly effective in accumulated-drift More >

  • Open Access

    ARTICLE

    Mebendazole Shows Antiproliferative and Antimigratory Effects in Paediatric Low-Grade Glioma Models

    Chiara Ferraro1, Michela Pizzoferrato1, Michela Graziano1, Tiziana Servidei2, Antonio Ruggiero2, Pierluigi Navarra1, Lucia Lisi1,*

    Oncology Research, Vol.34, No.7, 2026, DOI:10.32604/or.2026.071074 - 16 June 2026

    Abstract Objectives: Advances in molecular profiling of pediatric low-grade glioma have enabled targeted therapies to emerge as effective and better-tolerated alternatives to conventional chemotherapy, increasingly used in progressive or recurrent disease and may reduce long-term treatment toxicity. This study aimed to evaluate the repositioning of the anthelmintic drug mebendazole (MBZ) as an antiproliferative agent in pediatric glioma models, and to investigate potential synergistic effects in combination with vinblastine. Methods: Two well-established human pediatric glioma cell lines, RES 259 and RES 186, were exposed to MBZ alone or in combination with vinblastine. Cell viability, cytotoxicity, and tumor invasiveness… More >

  • Open Access

    ARTICLE

    Lightweight Complex-Valued Neural Network for Indoor Positioning

    Le Wang1, Bing Xu1,*, Peng Liu2, En Yuan1

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-14, 2026, DOI:10.32604/cmc.2025.070794 - 09 December 2025

    Abstract Deep learning has been recognized as an effective method for indoor positioning. However, most existing real-valued neural networks (RVNNs) treat the two constituent components of complex-valued channel state information (CSI) as real-valued inputs, potentially discarding useful information embedded in the original CSI. In addition, existing positioning models generally face the contradiction between computational complexity and positioning accuracy. To address these issues, we combine graph neural network (GNN) with complex-valued neural network (CVNN) to construct a lightweight indoor positioning model named CGNet. CGNet employs complex-valued convolution operation to directly process the original CSI data, fully exploiting… More >

  • Open Access

    ARTICLE

    Machine Learning-Based GPS Spoofing Detection and Mitigation for UAVs

    Charlotte Olivia Namagembe, Mohamad Ibrahim, Md Arafatur Rahman*, Prashant Pillai

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-20, 2026, DOI:10.32604/cmc.2025.070316 - 09 December 2025

    Abstract The rapid proliferation of commercial unmanned aerial vehicles (UAVs) has revolutionized fields such as precision agriculture and disaster response. However, their heavy reliance on GPS navigation leaves them highly vulnerable to spoofing attacks, with potentially severe consequences. To mitigate this threat, we present a machine learning-driven framework for real-time GPS spoofing detection, designed with a balance of detection accuracy and computational efficiency. Our work is distinguished by the creation of a comprehensive dataset of 10,000 instances that integrates both simulated and real-world data, enabling robust and generalizable model development. A comprehensive evaluation of multiple classification More >

  • Open Access

    REVIEW

    Targeting AMPK for Cancer Therapy: Metabolic Reprogramming as a Therapeutic Strategy

    Minseo Hong, Jea-Hyun Baek*

    Oncology Research, Vol.33, No.10, pp. 2699-2724, 2025, DOI:10.32604/or.2025.067487 - 26 September 2025

    Abstract AMP-activated protein kinase (AMPK) is a highly conserved serine/threonine kinase that functions as a central regulator of cellular energy status. In cancer, where metabolic reprogramming enables rapid proliferation and survival under stress, AMPK functions as a metabolic checkpoint that restrains tumor growth by inhibiting biosynthetic pathways and promoting catabolic processes, such as autophagy and fatty acid oxidation. Given its role in opposing many hallmarks of cancer metabolism, AMPK has attracted significant interest as a therapeutic target. This review examines the molecular mechanisms by which AMPK influences tumor progression and evaluates the preclinical and clinical evidence… More >

  • Open Access

    ARTICLE

    A Base Station Deployment Algorithm for Wireless Positioning Considering Dynamic Obstacles

    Aiguo Li1, Yunfei Jia2,*

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4573-4591, 2025, DOI:10.32604/cmc.2025.059184 - 06 March 2025

    Abstract In the context of security systems, adequate signal coverage is paramount for the communication between security personnel and the accurate positioning of personnel. Most studies focus on optimizing base station deployment under the assumption of static obstacles, aiming to maximize the perception coverage of wireless RF (Radio Frequency) signals and reduce positioning blind spots. However, in practical security systems, obstacles are subject to change, necessitating the consideration of base station deployment in dynamic environments. Nevertheless, research in this area still needs to be conducted. This paper proposes a Dynamic Indoor Environment Beacon Deployment Algorithm (DIE-BDA)… More >

  • Open Access

    ARTICLE

    XGBoost Based Multiclass NLOS Channels Identification in UWB Indoor Positioning System

    Ammar Fahem Majeed1,2,*, Rashidah Arsat1, Muhammad Ariff Baharudin1, Nurul Mu’azzah Abdul Latiff1, Abbas Albaidhani3

    Computer Systems Science and Engineering, Vol.49, pp. 159-183, 2025, DOI:10.32604/csse.2024.058741 - 03 January 2025

    Abstract Accurate non-line of sight (NLOS) identification technique in ultra-wideband (UWB) location-based services is critical for applications like drone communication and autonomous navigation. However, current methods using binary classification (LOS/NLOS) oversimplify real-world complexities, with limited generalisation and adaptability to varying indoor environments, thereby reducing the accuracy of positioning. This study proposes an extreme gradient boosting (XGBoost) model to identify multi-class NLOS conditions. We optimise the model using grid search and genetic algorithms. Initially, the grid search approach is used to identify the most favourable values for integer hyperparameters. In order to achieve an optimised model configuration,… More >

  • Open Access

    ARTICLE

    Development of Multi-Agent-Based Indoor 3D Reconstruction

    Hoi Chuen Cheng, Frederick Ziyang Hong, Babar Hussain, Yiru Wang, Chik Patrick Yue*

    CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 161-181, 2024, DOI:10.32604/cmc.2024.053079 - 15 October 2024

    Abstract Large-scale indoor 3D reconstruction with multiple robots faces challenges in core enabling technologies. This work contributes to a framework addressing localization, coordination, and vision processing for multi-agent reconstruction. A system architecture fusing visible light positioning, multi-agent path finding via reinforcement learning, and 360° camera techniques for 3D reconstruction is proposed. Our visible light positioning algorithm leverages existing lighting for centimeter-level localization without additional infrastructure. Meanwhile, a decentralized reinforcement learning approach is developed to solve the multi-agent path finding problem, with communications among agents optimized. Our 3D reconstruction pipeline utilizes equirectangular projection from 360° cameras to More >

  • Open Access

    ARTICLE

    Physical Layer Security of 6G Vehicular Networks with UAV Systems: First Order Secrecy Metrics, Optimization, and Bounds

    Sagar Kavaiya1, Hiren Mewada2,*, Sagarkumar Patel3, Dharmendra Chauhan3, Faris A. Almalki4, Hana Mohammed Mujlid4

    CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 3685-3711, 2024, DOI:10.32604/cmc.2024.053587 - 12 September 2024

    Abstract The mobility and connective capabilities of unmanned aerial vehicles (UAVs) are becoming more and more important in defense, commercial, and research domains. However, their open communication makes UAVs susceptible to undesirable passive attacks such as eavesdropping or jamming. Recently, the inefficiency of traditional cryptography-based techniques has led to the addition of Physical Layer Security (PLS). This study focuses on the advanced PLS method for passive eavesdropping in UAV-aided vehicular environments, proposing a solution to complement the conventional cryptography approach. Initially, we present a performance analysis of first-order secrecy metrics in 6G-enabled UAV systems, namely hybrid… More >

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