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  • Open Access

    ARTICLE

    On Progressive-Stress ALT under Generalized Progressive Hybrid Censoring Scheme for Quasi Xgamma Distribution

    Ehab M. Almetwally1,*, O. M. Khaled2, H. M. Barakat3

    CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.3, pp. 2957-2990, 2025, DOI:10.32604/cmes.2025.065446 - 30 June 2025

    Abstract Accelerated life tests play a vital role in reliability analysis, especially as advanced technologies lead to the production of highly reliable products to meet market demands and competition. Among these tests, progressive-stress accelerated life tests (PSALT) allow for continuous changes in applied stress. Additionally, the generalized progressive hybrid censoring (GPHC) scheme has attracted significant attention in reliability and survival analysis, particularly for handling censored data in accelerated testing. It has been applied to various failure models, including competing risks and step-stress models. However, despite its growing relevance, a notable gap remains in the literature regarding… More >

  • Open Access

    REVIEW

    A Review on the Research Progress of Layered Double Hydroxides Electrode Materials for Supercapacitors

    Hengzheng Li1,2, Jie Yang1,*

    Energy Engineering, Vol.122, No.7, pp. 2589-2609, 2025, DOI:10.32604/ee.2025.063268 - 27 June 2025

    Abstract Layered double hydroxides (LDHs) are a class of transition metal-based materials characterized by their two-dimensional nano-layered structure. They offer several advantages, such as easy adjustability of morphology and structure and simple preparation methods, making them highly promising for the development of low-cost, high energy density supercapacitors. This article begins with a brief introduction to the basic structure, energy storage mechanism, and application challenges of LDHs. It then proceeds to summarize the innovations in the preparation methods of LDH electrode materials, such as the application of high precision synthesis technologies including component regulation, amorphization, and the… More >

  • Open Access

    ARTICLE

    circACTN4 promotes breast cancer cell cycle progression and oncogenesis via c-MYC induced histone H4 acetylation

    KEFAN LIU1, XIAOSONG WANG1, XIN YANG1, BOWEN SHI1, LEI XING2,*, JUNXIA CHEN1,*

    Oncology Research, Vol.33, No.7, pp. 1709-1722, 2025, DOI:10.32604/or.2025.061721 - 26 June 2025

    Abstract Background: Accumulating studies have shown the important role of circular RNAs (circRNAs) in the oncogenesis and metastasis of various cancers. We previously reported that circACTN4 could bind with FUBP1 to promote tumorigenesis and the development of breast cancer (BC) by increasing the expression of MYC. However, its exact molecular mechanism and biological function have not been fully elucidated. Methods: Here, Circular RNA microarray analysis was conducted in 3 pairs of BC and paracancerous tissues. The expression of circACTN4 in BC cells and tissues was detected via reverse transcription‒quantitative PCR (RT‒qPCR). Cell Counting Kit-8 (CCK-8), 5-ethynyl-2-deoxyuridine… More > Graphic Abstract

    circACTN4 promotes breast cancer cell cycle progression and oncogenesis via c-MYC induced histone H4 acetylation

  • Open Access

    ARTICLE

    Correlation of senescence-related gene FEN1 on neuroblastoma progression and cisplatin chemotherapy sensitivity

    YOUYANG HU1,#, YISHU LUO1,#, TIANYUE XIE1, YUEHUA CHEN1,2, JUN ZHAO1, WEICHAO JI3, ZHIWEI YAN3, SITONG QIU3, KEXIN GAO3, HAIXIA ZHU4, LIMIN MA1,*, QIYOU YIN1,*

    Oncology Research, Vol.33, No.7, pp. 1695-1708, 2025, DOI:10.32604/or.2025.060021 - 26 June 2025

    Abstract Objective: Neuroblastoma (NB) is frequently associated with high-risk pediatric cases that demonstrate limited response to cisplatin, contributing to a poor prognosis. Recent studies have explored the role of tumor cell senescence in increasing sensitivity to this chemotherapy agent. This study aims to identify genes related to cell senescence in children diagnosed with NB, evaluate their influence on cisplatin sensitivity, and investigate potential strategies to enhance the efficacy of chemotherapy. Methods: Gene expression profiles and clinical data were obtained for 498 NB patients from the GEO database (GSE49710). The study focused on identifying genes that were… More >

  • Open Access

    ARTICLE

    ETV1 transcriptional manipulation of KIFC1 regulates the progression of pancreatic cancer

    FANGFANG HU1, ZHIBIN BAI2, YANG WANG1, HAODONG TANG3, JIAHUA ZHOU1,*

    Oncology Research, Vol.33, No.7, pp. 1723-1737, 2025, DOI:10.32604/or.2025.059631 - 26 June 2025

    Abstract Background: Kinesin-14 family protein 1 (KIFC1) is abnormally overexpressed in various cancers, and the transcription factor ETS variant 1 (ETV1) is an oncogenic transcription factor in tumors. The potential binding sites on the KIFC1 promoter by ETV1 were observed; however, no evidence supports that ETV1 targets KIFC1. Aims: This study aimed to investigate the relationship between KIFC1 and ETV1, and their effects and mechanisms in pancreatic cancer. Methods: Pan-cancer analysis of KIFC1 expression was performed in GEPIA2 database. KIFC1 expression levels were determined by immunohistochemistry (IHC) in our pancreatic cancer cohort. The correlation between KIFC1… More >

  • Open Access

    ARTICLE

    Gallic acid suppresses esophageal squamous cell carcinoma progression and enhances cisplatin chemosensitivity through IL-6/STAT3/Notch pathway

    NURAN BEDOLLA#, HAO WU#, LINYU LIU, XUETING LIU, YANLI REN*

    Oncology Research, Vol.33, No.6, pp. 1473-1484, 2025, DOI:10.32604/or.2025.060151 - 29 May 2025

    Abstract Background: Gallic acid (GA), a plant-derived polyphenol, possesses diverse biological functions such as reducing inflammation and against tumors. Currently, the influence of GA on the resistance of esophageal squamous cell carcinoma (ESCC) cells to cisplatin (DDP) is not well understood. Methods: Cell counting kit-8 assay examined how GA affected KYSE30 and TE-1 cell viability. 5-Ethynyl-2′-deoxyuridine and TdT-mediated dUTP Nick-End labeling staining detected cell proliferation and apoptosis. Clone formation assay, flow cytometry, Carboxyfluorescein diacetate succinimidyl ester fluorescent probes, and Transwell assay determined cell biological properties, and 2′,7′-Dichlorofluorescin diacetate (DCFH-DA) fluorescent probes detected oxidative stress levels. Signal… More > Graphic Abstract

    Gallic acid suppresses esophageal squamous cell carcinoma progression and enhances cisplatin chemosensitivity through IL-6/STAT3/Notch pathway

  • Open Access

    CORRECTION

    Correction: LncRNA PCGEM1 facilitates cervical cancer progression via miR-642a-5p/KIF5B axis

    YUANLIN LIU1,3, YAN LIU2, YAN WANG2, QIANG WANG2, YAN YAN1, DANDAN ZHANG2,*, HUIQIN LIU2,*

    Oncology Research, Vol.33, No.6, pp. 1505-1505, 2025, DOI:10.32604/or.2024.056768 - 29 May 2025

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    Research Progress on Multi-Modal Fusion Object Detection Algorithms for Autonomous Driving: A Review

    Peicheng Shi1,*, Li Yang1, Xinlong Dong1, Heng Qi2, Aixi Yang3

    CMC-Computers, Materials & Continua, Vol.83, No.3, pp. 3877-3917, 2025, DOI:10.32604/cmc.2025.063205 - 19 May 2025

    Abstract As the number and complexity of sensors in autonomous vehicles continue to rise, multimodal fusion-based object detection algorithms are increasingly being used to detect 3D environmental information, significantly advancing the development of perception technology in autonomous driving. To further promote the development of fusion algorithms and improve detection performance, this paper discusses the advantages and recent advancements of multimodal fusion-based object detection algorithms. Starting from single-modal sensor detection, the paper provides a detailed overview of typical sensors used in autonomous driving and introduces object detection methods based on images and point clouds. For image-based detection… More >

  • Open Access

    ARTICLE

    Optimization and Intelligent Control in Hybrid Renewable Energy Systems Incorporating Solar and Biomass

    Arpita Johri1,2,*, Varnita Verma3, Mainak Basu1,*

    Energy Engineering, Vol.122, No.5, pp. 1887-1918, 2025, DOI:10.32604/ee.2025.062355 - 25 April 2025

    Abstract The globe faces an urgent need to close the energy demand-supply gap. Addressing this difficulty requires constructing a Hybrid Renewable Energy System (HRES), which has proven to be the most appropriate solution. HRES allows for integrating two or more renewable energy resources, successfully addressing the issue of intermittent availability of non-conventional energy resources. Optimization is critical for improving the HRES’s performance parameters during implementation. This study focuses on HRES using solar and biomass as renewable energy supplies and appropriate energy storage technologies. However, energy fluctuations present a problem with the power quality of HRES. To… More > Graphic Abstract

    Optimization and Intelligent Control in Hybrid Renewable Energy Systems Incorporating Solar and Biomass

  • Open Access

    REVIEW

    Research Progress of Nanotechnology on Efficient and Green Technologies for Wood Preservation: A Review

    Yuxin He1,#, Yixin Li2,#, Qiaoguang Li1, Wenqing Xiao1,*, Guijun Xie2,*

    Journal of Renewable Materials, Vol.13, No.4, pp. 699-718, 2025, DOI:10.32604/jrm.2025.058349 - 21 April 2025

    Abstract Wood, recognized as a renewable and environmentally sustainable material, plays a crucial role as an alternative energy resource within the construction industry. However, it is highly susceptible to mold and decay fungi, which can lead to surface discoloration and potentially compromise the structural integrity of wood. The advancement of nanotechnology has introduced innovative strategies for wood protection, enhancing its performance while imparting additional properties. Various approaches including nanosized metals, polymer nanocomposite and coating treatments are actively being explored in this field. Furthermore, integrating bio-based materials with nanotechnology offers a green and sustainable method for wood More >

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