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  • Open Access

    ARTICLE

    Characterization, In Vitro Dissolution, and Drug Release Kinetics in Hard Capsule Shells Made from Hydrolyzed κ-Carrageenan and Xanthan Gum

    Tri Susanti1,2, Syahnur Haqiqoh1, Pratiwi Pudjiastuti2,*, Siti Wafiroh2,*, Esti Hendradi3, Oktavia Eka Puspita4, Nashriq Jailani5

    Journal of Renewable Materials, Vol.13, No.9, pp. 1841-1857, 2025, DOI:10.32604/jrm.2025.02024-0084 - 22 September 2025

    Abstract This study aims to enhance the mechanical properties, disintegration, and dissolution rates of cross-linked carrageenan (CRG) capsule shells by shortening the long chains of CRG through a hydrolysis reaction with citric acid (CA). The hydrolysis of CRG was carried out using varying concentrations of CA, resulting in hydrolyzed CRG (HCRG). This was followed by cross-linking with xanthan gum (XG) and the addition of sorbitol (SOR) as a plasticizer. The results indicated that the optimal swelling capacity of HCRG-XG/SOR hard-shell capsules occurred at a CA concentration of 0.5%, achieving a maximum swelling rate of 445.39% after… More >

  • Open Access

    ARTICLE

    Temperature Control Performance and Cooling Release Characteristics of PCM in Large Space: Case Study of Cold Storage

    Zhengrong Shi1,3, Hai Hong1, Yanming Shen2,*, Jingyong Cai1,*

    Energy Engineering, Vol.122, No.3, pp. 885-903, 2025, DOI:10.32604/ee.2025.061976 - 07 March 2025

    Abstract Phase Change Material (PCM)-based cold energy storage system (CESS) can effectively utilize the peak and valley power resources to reduce the excessive dependence on the power grid. In this study, a PCM-based CESS was designed for cold storage applications. The optimal number of PCM plates was determined through numerical simulations to meet the required cold storage temperature and control time. Additionally, the air temperature field, flow field, and melting characteristics of the PCM plates during the cooling release process were analyzed. The effects of plate positioning and thickness on the cooling release performance were further… More >

  • Open Access

    ARTICLE

    Preparation and Sustained Release of 2-Hydroxyethyl Methacrylate -N-Vinyl-2-Pyrrolidone Hydrogel for Ophthalmic Drug

    Xiaojuan He1, Chanyuan Li1, Shaokang Wang1, Jingyi Zhu1, Yabin Zhang1,*, Zhen Guo2, Lihua Wu3,*

    Journal of Polymer Materials, Vol.41, No.4, pp. 263-279, 2024, DOI:10.32604/jpm.2024.055821 - 16 December 2024

    Abstract Eye drops are the usual method to treat eye diseases, and gel polymer provides the carrier which could be used for ophthalmic drug delivery. However, the stable and sustained release is the main issue for the ophthalmic drug and is concerned by many researchers. In this study, composite hydrogels were prepared using 2-hydroxyethyl methacrylate (HEMA), and N-vinyl-2-pyrrolidone (NVP) used for ophthalmic drug loading and release. According to the results of Fourier transform infrared spectroscopy (FTIR), the disappearance of the C=C bond in hydrogel indicated that the copolymerization reaction between HEMA and NVP was successful. The… More > Graphic Abstract

    Preparation and Sustained Release of 2-Hydroxyethyl Methacrylate -N-Vinyl-2-Pyrrolidone Hydrogel for Ophthalmic Drug

  • Open Access

    ARTICLE

    Synthesis and Characterization of Photothermal Responded Chitosan/Nanodiamond-Based Composite Beads with Enhanced Control Release Properties

    Yu Luo1,2,3, Mengna Zong1,2,3, Jin Wang1,2,3, Xuechun Wang1,2,3, Bo Bai1,2,3,*, Chunyu Zhou1,2,3,*, Junlin Zhu1,2,3, Jianyu Xing1,2,3, Moses M. C. Carlon Jr1,2,3

    Journal of Polymer Materials, Vol.41, No.2, pp. 87-103, 2024, DOI:10.32604/jpm.2024.054660 - 09 August 2024

    Abstract In this research, we developed a novel photo-stimulation-responsive composite sphere with a semi-interpenetrating polymer network (semi-IPN) structure, synthesized via an alkali gel method, to enhance the efficiency of agrochemicals. Chitosan (CS) serves as the structural matrix and protective shell, with a loading capacity for the plant growth hormone indole-3-butyric acid (IBA) of up to 41.73 μg/mg, effectively controlling the abrupt release of auxin. The incorporation of photothermal detonation nanodiamond (DND) and the photosensitive poly(N-isopropylacrylamide) (PNIPAm) endows the spheres with the ability to respond to light and temperature stimuli, achieving intelligent control over IBA release. Characterization… More >

  • Open Access

    ARTICLE

    A New Solution to Intrusion Detection Systems Based on Improved Federated-Learning Chain

    Chunhui Li1,*, Hua Jiang2

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4491-4512, 2024, DOI:10.32604/cmc.2024.048431 - 20 June 2024

    Abstract In the context of enterprise systems, intrusion detection (ID) emerges as a critical element driving the digital transformation of enterprises. With systems spanning various sectors of enterprises geographically dispersed, the necessity for seamless information exchange has surged significantly. The existing cross-domain solutions are challenged by such issues as insufficient security, high communication overhead, and a lack of effective update mechanisms, rendering them less feasible for prolonged application on resource-limited devices. This study proposes a new cross-domain collaboration scheme based on federated chains to streamline the server-side workload. Within this framework, individual nodes solely engage in… More >

  • Open Access

    ARTICLE

    A Cooperated Imperialist Competitive Algorithm for Unrelated Parallel Batch Machine Scheduling Problem

    Deming Lei*, Heen Li

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 1855-1874, 2024, DOI:10.32604/cmc.2024.049480 - 15 May 2024

    Abstract This study focuses on the scheduling problem of unrelated parallel batch processing machines (BPM) with release times, a scenario derived from the moulding process in a foundry. In this process, a batch is initially formed, placed in a sandbox, and then the sandbox is positioned on a BPM for moulding. The complexity of the scheduling problem increases due to the consideration of BPM capacity and sandbox volume. To minimize the makespan, a new cooperated imperialist competitive algorithm (CICA) is introduced. In CICA, the number of empires is not a parameter, and four empires are maintained More >

  • Open Access

    ARTICLE

    Fatigue Crack Propagation Law of Corroded Steel Box Girders in Long Span Bridges

    Ying Wang1,*, Longxiao Chao1, Jun Chen2, Songbai Jiang1

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 201-227, 2024, DOI:10.32604/cmes.2024.046129 - 16 April 2024

    Abstract In order to investigate the fatigue performance of orthotropic anisotropic steel bridge decks, this study realizes the simulation of the welding process through elastic-plastic finite element theory, thermal-structural sequential coupling, and the birth-death element method. The simulated welding residual stresses are introduced into the multiscale finite element model of the bridge as the initial stress. Furthermore, the study explores the impact of residual stress on crack propagation in the fatigue-vulnerable components of the corroded steel box girder. The results indicate that fatigue cracks at the weld toe of the top deck, the weld root of… More > Graphic Abstract

    Fatigue Crack Propagation Law of Corroded Steel Box Girders in Long Span Bridges

  • Open Access

    ARTICLE

    A Rapid Parameter of Enzyme-Treated Cellulosic Material Revealed by Reducing Sugar Release

    Verônica Távilla Ferreira Silva, Adriane Maria Ferreira Milagres*

    Journal of Renewable Materials, Vol.12, No.3, pp. 539-551, 2024, DOI:10.32604/jrm.2023.045726 - 11 April 2024

    Abstract This study was conducted to evaluate the effectiveness of enzymes in purifying and reducing the degree of polymerization of cellulose for the production of dissolving pulp. Our goal was to determine the contributions of xylanase (X) and endoglucanase (EG) in the treatment of pulp, specifically by quantifying the formation of soluble and insoluble reducing sugars using the dinitrosalycilic acid (DNS) test. Predominantly, the release of soluble reducing sugars (RSSol) was enhanced after xylanase treatment, while endoglucanase (EG) treatment led to changes in insoluble reducing sugars (RSIns). The maximum synergism was observed for RSIns when a… More > Graphic Abstract

    A Rapid Parameter of Enzyme-Treated Cellulosic Material Revealed by Reducing Sugar Release

  • Open Access

    ARTICLE

    Influences of the Fresh Air Volume on the Removal of Cough-Released Droplets in a Passenger Car of a High-Speed Train Using CFD

    Jun Xu1, Kai Bi1, Yibin Lu2,*, Tiantian Wang2,3, Hang Zhang2, Zeyuan Zheng3, Fushan Shi3, Yaxin Zheng3, Xiaoying Li2, Jingping Yang3

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2727-2748, 2024, DOI:10.32604/cmes.2023.031341 - 15 December 2023

    Abstract The spread and removal of pollution sources, namely, cough-released droplets in three different areas (front, middle, and rear areas) of a fully-loaded passenger car in a high-speed train under different fresh air flow volume were studied using computational fluid dynamics (CFD) method. In addition, the structure of indoor flow fields was also analysed. The results show that the large eddies are more stable and flow faster in the air supply under Mode 2 (fresh air volume: 2200 m3/h) compared to Mode 1 (fresh air volume: 1100 m3/h). By analysing the spreading process of droplets sprayed at different locations… More >

  • Open Access

    PROCEEDINGS

    Analytical Mixed Mode Partition Method for One Dimensional Fracture of Composite DCBs

    Michele Straface1, Wu Xu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.2, pp. 1-1, 2023, DOI:10.32604/icces.2023.09657

    Abstract Fracture analysis is a problem playing a fundamental role in the fields of Aerospace Mechanics and Structural Mechanics. The paper deals with the analysis of the most essential among the fracture problems: the one-dimensional crack in a double cantilever beam. The report presents a reliable analytical method to correctly partition the energy release rates into pure fracture modes, appliable to both isotropic and composite beams with clearly known mechanical properties, subject to shearing or bending loads. The adopted strategy is based on the Timoshenko’s kinematic model and exploits the theoretical definition of the I and More >

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