Gabrielle Yankelevich^1,*, Jessica Swaim¹, Ian Coate¹, Margaret Stroud¹, William Stallings¹, Virgilio George², M. Lance Tavana³, Harry Clarke¹

Canadian Journal of Urology, Vol.32, No.1, pp. 37-42, 2025, DOI:10.32604/cju.2025.064684 - 20 March 2025

Abstract Objectives: To assess outcomes of rectourethral fistula repair utilizing a gracilis flap in a largely radiated cohort. Patients and Methods: We performed a retrospective review of all gracilis interposition flap reconstruction surgeries performed for RUF at a university hospital in South Carolina between January 2010 and June 2023. All repairs utilized a multidisciplinary approach with urology, colorectal, and plastic surgery teams. Post-operatively, patients were maximally drained with foley catheter and suprapubic tube (SPT). Initial voiding cystourethrogram (VCUG) was performed at 4 weeks post-repair. If there was a persistent leak, catheter drainage was maintained for 4 additional… More >

Rivky Afanda¹, Ahmad Zaki^1,2,*

Structural Durability & Health Monitoring, Vol.19, No.2, pp. 265-284, 2025, DOI:10.32604/sdhm.2024.053084 - 15 January 2025

Abstract Concrete is one of the most important elements in building construction. However, concrete used in construction is susceptible to damage due to corrosion. The influence of corrosive substances causes changes in the reinforcing steel and affects the strength of the structure. The repair method is one approach to overcome this problem. This research aims to determine the effect of grouting and jacketing repairs on corroded concrete. The concrete used has dimensions of 15 cm × 15 cm × 60 cm with planned corrosion variations of 50%, 60%, and 70%. The test objects were tested using… More >

ENRICO CALIMAN^1,2, SARA FANCELLI^1,2, FEDERICO SCOLARI³, ADRIANO PASQUI⁴, CLARA MANNESCHI⁴, DANIELE LAVACCHI¹, FRANCESCA MAZZONI⁴, FRANCESCA GENSINI⁵, VALERIA PASINI⁶, CAMILLA EVA COMIN^2,7, LUCA VOLTOLINI^2,8, SERENA PILLOZZI^1,2,*, LORENZO ANTONUZZO^1,2,4

Oncology Research, Vol.33, No.1, pp. 45-55, 2025, DOI:10.32604/or.2024.050161 - 20 December 2024

Abstract Background: Platinum chemotherapy (CT) remains the backbone of systemic therapy for patients with small-cell lung cancer (SCLC). The nucleotide excision repair (NER) pathway plays a central role in the repair of the DNA damage exerted by platinum agents. Alteration in this repair mechanism may affect patients’ survival. Materials and Methods: We conducted a retrospective analysis of data from 38 patients with extensive disease (ED)-SCLC who underwent platinum-CT at the Clinical Oncology Unit, Careggi University Hospital, Florence (Italy), from 2015 to 2020. mRNA expression analysis and single nucleotide polymorphism (SNP) characterization of three NER pathway genes—namely ERCC1, ERCC2,… More >

Sameh M. Said^1,2,*, Kristin C. Greathouse³, Christina McCarthy³, Megan Khan³, Molly Hagen⁴, Nicholas Brown⁵, Sacha Kumar⁵, Mahmoud I. Salem⁶, James Flaherty⁷, Yasin Essa¹

Congenital Heart Disease, Vol.19, No.6, pp. 563-575, 2024, DOI:10.32604/chd.2025.061819 - 27 January 2025

Abstract Objective: Vertical right thoracotomy (VRAT) has become an alternative to sternotomy for the repair of non-complex congenital heart defects in our infants and children. Summary Background Data: Limited data exists on the comparison of the two approaches. Methods: The present study consisted of two groups; Group I: (sternotomy; 33 patients) and Group II: (VRAT; 35 patients). We compared the two groups on operative data, hours of invasive lines, narcotics used, length of stay, and total variable cost of stay. Results: The most frequent procedures were atrial and ventricular septal defect closure (25 patients, 75.8% in Group I)… More >

Pieter C. van de Woestijne^1,*, Ingrid M. van Beynum², Kevin M. Veen³, Ad J. J. C Bogers¹

Congenital Heart Disease, Vol.19, No.6, pp. 593-601, 2024, DOI:10.32604/chd.2025.060607 - 27 January 2025

Abstract Background: Construction of a central shunt by connection of hypoplastic true pulmonary arteries to the ascending aorta (AO) can be performed as a first step in staged repair of pulmonary atresia with ventricular septal defect and major aorto-pulmonary collateral arteries (PA-VSD-MAPCAs) intended to promote growth and development of the central pulmonary arteries. Methods: To determine early and intermediate-term growth of true pulmonary arteries after their connection to the AO as a first step in staged repair of PA-VSD-MAPCAs, we reviewed all angiographic studies and CT imaging of patients, treated in our tertiary referral center in… More >

Edo Bedzra^1,*, Eli Contorno², Herra Javed², Amna Qasim³, James St. Louis⁴, Taufiek Konrad Rajab²

Congenital Heart Disease, Vol.19, No.6, pp. 541-562, 2024, DOI:10.32604/chd.2025.059788 - 27 January 2025

Abstract Since the first identification of Tetralogy of Fallot in 1671, consisting of a combination of anatomical defects including biventricular origin of the aorta, maligned ventricular septal defect, overriding aorta, and narrowing or atresia of the pulmonary outflow tract. The first successful operation consisted of a shunt between the left subclavian artery and pulmonary artery. Following this palliative procedure, complete repair is performed once the patient reaches indicative criteria. Since the first attempts at surgical palliation and repair, techniques and outcomes have improved drastically. Definitive repair of Tetralogy of Fallot consists of a multi-patch closure of More >

Junshan Hu^1,2,*, Shiqing Mi¹, Jinrong Fang¹, Wei Tian¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.4, pp. 1-2, 2024, DOI:10.32604/icces.2024.011840

Abstract This research aims to investigate efficient repair techniques of cracked Ti-alloy aircraft structures with adhesively bonded carbon fiber-reinforced polymer composite patches. The repaired specimens in the configuration of a Ti-alloy butt joint with one-side bonded composite patch were prepared under multiple repair factors including patch thickness, patch length, adhesive thickness, cure pressure, patch layup and surface treatment. The repair efficiency was evaluated by loading behavior, bonded interface microstructure and failure mode. The three-dimensional (3D) finite element (FE) model has been established. Based on 3D Hashin failure criteria, the damage initiation and evolution in CFRP were… More >

Hexin Yue¹, Cian Vyas^1,2,*, Paulo Bartolo^1,2,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.011598

Abstract Peripheral nerve injury can result in significant motor or sensory impairment. Traditional treatments have certain drawbacks and often result in suboptimal clinical results. To overcome these limitations, tissue engineering and bioprinting technologies are promising approaches for manufacturing nerve guidance conduits (NGCs). NGCs are tubular biostructures that bridge the nerve injury site, provide an appropriate microenvironment, and promote peripheral nerve regeneration by guiding axonal growth. The architecture of NGCs needs to mimic the morphology of natural peripheral nerves by designing their topology to regulate nerve cell behaviours. Topographic guidance cues are an effective element in improving… More >

Sameh M. Said^1,2,*, Yasin Essa¹

Congenital Heart Disease, Vol.19, No.4, pp. 407-417, 2024, DOI:10.32604/chd.2024.055636 - 31 October 2024

Abstract Minimally invasive approaches for cardiac surgery in children have been lagging in comparison to the adult world. A wide range of the most common congenital heart defects in infants and children can be repaired successfully through a variety of non-sternotomy incisions. This has been shown to be associated with superior cosmetic results, shorter hospital stays, and rapid return to full activity compared to sternotomy. These approaches have been around for decades, but they have not been widely adopted for a variety of reasons. Right axillary thoracotomy is one of these approaches that we believe should More >

Hiroki Nagamine¹, Masaru Miura^1,*, Jun Maeda¹, Takumi Nishiki¹, Maasa Sato², Fumie Takechi³, Shigeru Tateno⁴, Tomoko Ishizu⁵, Yumi Shiina⁶, Ken Kato⁷, Hiroshi Ono⁸, Hiroyuki Yamagishi⁹, Koichiro Niwa⁶

Congenital Heart Disease, Vol.19, No.4, pp. 351-362, 2024, DOI:10.32604/chd.2024.051837 - 31 October 2024

Abstract Background: Aortic root dilatation occurs in adults with tetralogy of Fallot (TOF) after surgical repair, but the longitudinal changes are unclear. The main research aim is to determine the annual dilatation rate of aorta in adults with repaired TOF. Methods: The present, multicentric, prospective cohort study assessed the rate of aortic diameter change in adults aged 20 years or older with TOF, including pulmonary artery atresia, who underwent surgical repair. Clinical data, focusing on echocardiograms, were collected at three-year intervals from seven hospitals. Results: In total, 104 patients (58 males; median age: 29 years) were enrolled.… More > Graphic Abstract