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  • Open Access

    REVIEW

    The Immune-Centric Revolution in the Treatment of Musculoskeletal Disease: Autologous PBMNC and PRP-PBMNC Enriched—A Narrative Review

    Andrea De Matthaeis1, Laura Rehak2,*, Maria Bianchi3, Rossana Putzulu3, Nicola Piccirillo3,4, Giulio Maccauro1

    BIOCELL, Vol.50, No.5, 2026, DOI:10.32604/biocell.2026.073783 - 13 May 2026

    Abstract For over two decades, mesenchymal stem cells (MSCs) have been recognised as the cornerstone of orthobiologic treatments for musculoskeletal diseases. However, clinical evidence increasingly indicates that MSC engraftment in inflamed tissues is minimal and transient, with effects mainly driven by paracrine and immunomodulatory mechanisms induced by macrophage efferocytosis. This evolving paradigm emphasises the immune system as the central orchestrator of tissue repair. Peripheral blood mononuclear cells (PBMNCs) have emerged as potent effectors of regenerative inflammation, mediating apoptotic cell clearance through efferocytosis, facilitating the transition of macrophages from pro-inflammatory (M1) to reparative (M2) phenotypes, and releasing… More >

  • Open Access

    REVIEW

    A Review of Advancements in Deep Learning Approaches for Intrusion Detection Systems

    Akash Garg*

    Journal on Artificial Intelligence, Vol.8, pp. 273-298, 2026, DOI:10.32604/jai.2026.079401 - 12 May 2026

    Abstract As cyber threats continue to evolve in scale and sophistication, the need for intelligent and adaptive security mechanisms has become increasingly urgent. Intrusion Detection Systems (IDS) are critical components in safeguarding computer networks from malicious activities. This review paper presents a comprehensive analysis of recent advancements in deep learning-based IDS, examining various architectures such as convolutional neural networks (CNNs), recurrent neural networks (RNNs), autoencoders, and generative adversarial networks (GANs). The study compares traditional intrusion detection techniques with modern deep learning approaches, highlighting their strengths, limitations, and suitability for real-world deployment. Special attention is given to… More >

  • Open Access

    Review of the Application of Tellurium and Tellurides in Sodium Metal Batteries

    Shan Yuan1,2, Fei Wang2,*, Jinping Zhang2,*, Yuxin Jiang2, Kaibo Gu2, Chenhao Qiao2, Yutong Bai2, Jie Yu2, Quan Chen1, Dedi Han3

    Chalcogenide Letters, Vol.23, No.4, 2026, DOI:10.32604/cl.2026.082805 - 09 May 2026

    Abstract Sodium metal batteries stand as a highly promising electrochemical energy storage system; however, their commercialization is severely impeded by challenges such as anode dendrite formation, the shuttle effect of highly reactive intermediates at the cathode, electrode volume expansion, and interfacial instability. Owing to their high electronic conductivity, high theoretical specific capacity, and superior sodiumphilic affinity, tellurium and its tellurides have emerged as pivotal functional materials for enhancing the performance of sodium metal batteries. This study reviews the advancements in their applications within sodium metal batteries, elaborates rational design strategies carbon-based composites, alloying, and heterostructure construction More >

  • Open Access

    REVIEW

    The Semantic Design Space of Retrieval-Augmented Recommender Systems: A Systematic Review of LLM-Based Approaches

    Minhyeok Choi1, Imran Ahsan2, Hyunwook Yu1, Taeyoung Choe1, Mucheol Kim1,*

    CMC-Computers, Materials & Continua, Vol.88, No.1, 2026, DOI:10.32604/cmc.2026.079504 - 08 May 2026

    Abstract Large language models (LLMs) are increasingly integrated into recommender systems to support semantic reasoning, natural language understanding, and user-adaptive personalization. However, their reliance on static parametric knowledge and fixed representations limits robustness in dynamic environments, particularly under long-tail and cold-start conditions. Retrieval-augmented architectures have emerged to address these limitations by grounding LLMs in external, non-parametric knowledge sources. This systematic literature review synthesizes 138 peer-reviewed studies published between 2023 and 2025 in conferences and journals, focusing on retrieval-augmented and LLM-enhanced recommendation. We analyze these works through a three-dimensional framework covering: (i) domain application, (ii) semantic feature… More >

  • Open Access

    REVIEW

    A Review of Applications and Challenges of Large Language Models for Foundry Intelligence in the Casting Industry

    Yutong Guo1,2, Jianying Yang1,3, Chao Yang1,3,*

    CMC-Computers, Materials & Continua, Vol.88, No.1, 2026, DOI:10.32604/cmc.2026.077820 - 08 May 2026

    Abstract Large language models (LLMs) and related foundation-model workflows are emerging as promising tools for advancing foundry intelligence across the casting value chain. This review examines their applications in material design and property prediction, process parameter optimization and intelligent control, and defect detection and quality tracing in casting environments. The surveyed studies indicate that LLM-enabled systems can help integrate unstructured technical knowledge with multimodal industrial data. This integration supports composition design, simulation-assisted process optimization, diagnostic reasoning, and knowledge-grounded decision support. However, current evidence shows that the transition from pilot demonstrations to robust industrial deployment remains constrained More >

  • Open Access

    REVIEW

    IoT-Driven Intelligent Transportation System in the Era of 6G and AI: A Review

    Muhammet Ali Karabulut1, A. F. M. Shahen Shah2, Al-Sakib Khan Pathan3,*, Phillip G. Bradford4

    CMC-Computers, Materials & Continua, Vol.88, No.1, 2026, DOI:10.32604/cmc.2026.077625 - 08 May 2026

    Abstract Today, technological progress is broad and deep. The next generation networks and systems will integrate features, technologies, and models requiring smooth cooperation between new and old technologies. This survey’s uniqueness is that it considers an integrated, hybrid and heterogeneous future where Internet of Things (IoT), Sixth-Generation (6G) mobile communications technology, and Artificial Intelligence (AI) will work together, providing a smart and connected Intelligent Transportation System (ITS). This smart ITS will give better road safety and optimized travel. Currently, there is a scarcity of surveys focusing particularly on smart ITS that is expected soon. In this More >

  • Open Access

    REVIEW

    A Review of Artificial Intelligence in Boiling Heat Transfer: Predictive Modeling, Dynamic Characterization, and Methodological Advances

    Wei-Chen Tang, Xin Chen, Fei Dong*

    FDMP-Fluid Dynamics & Materials Processing, Vol.22, No.4, 2026, DOI:10.32604/fdmp.2026.079861 - 07 May 2026

    Abstract Boiling heat transfer remains a cornerstone of efficient thermal management, with far-reaching implications for energy systems and industrial processes. Advances in this field not only deepen fundamental scientific understanding but also enable transformative improvements in energy efficiency, equipment performance, and operational safety. Contemporary research in this area focuses on accurate parameter prediction, intelligent image analysis, and quantitative characterization of bubble dynamics, collectively advancing both mechanistic insight and engineering optimization. In this context, artificial intelligence (AI), encompassing machine learning and deep learning techniques, has emerged as a powerful paradigm, offering significant advantages in predictive accuracy, data-driven… More >

  • Open Access

    REVIEW

    Hot Wall Condensers in Domestic Refrigerators: A Review of Enhancements from Past to Present, Performance Parameters, and Future Perspectives

    Gürcan Durmaz1,*, Gökhan Gürlek2

    Frontiers in Heat and Mass Transfer, Vol.24, No.2, 2026, DOI:10.32604/fhmt.2026.075332 - 30 April 2026

    Abstract This study examines the evolution of condenser technologies in household refrigerators, focusing on the potential for improving energy efficiency with hot-wall condensers (HWCs). Factors influencing this development, including refrigerant changes, consumer expectations, global regulations, and environmental factors, are evaluated. Design features, advantages, disadvantages, limitations, and comparisons with other condenser types are presented for HWCs. The review identifies key parameters affecting HWC performance: pipe diameter and pitch, outer surface material properties, adhesive tape properties, and contact resistances. The effects of environmental factors such as ambient temperatures and heat transfer coefficients are also considered. The results indicate… More > Graphic Abstract

    Hot Wall Condensers in Domestic Refrigerators: A Review of Enhancements from Past to Present, Performance Parameters, and Future Perspectives

  • Open Access

    REVIEW

    Biostimulants in Modern Agriculture: A Comprehensive Review with Emphasis on Protein Hydrolysates

    Matthew Starr1, Lori Unruh-Snyder1,*, Luke Gatiboni1, Koralalage Jayaratne2

    Phyton-International Journal of Experimental Botany, Vol.95, No.4, 2026, DOI:10.32604/phyton.2026.072898 - 28 April 2026

    Abstract Biostimulants, categorized as microbial or non-microbial, including humic substances, seaweed extracts, chitosan, or protein hydrolysates (PHs), have gained significant attention in modern agriculture for their ability to enhance crop productivity, improve nutrient use efficiency, and increase resilience to abiotic and biotic stresses, while reducing dependence on conventional agrochemicals. This review synthesizes the historical development, classification, mechanisms of action, and agronomic benefits of biostimulants, with a particular emphasis on PHs, which are mixtures of amino acids, peptides, and polypeptides derived from plant or animal proteins through enzymatic, chemical, or thermal hydrolysis. The concept of biostimulants has… More >

  • Open Access

    BOOK REVIEW

    Book Review: Gonot-Schoupinsky, F., & Mayer, C.-H. (2025). Positive autoethnography: An introduction to theory and practice. Emerald Publishing Limited. ISBN: 978-1-80592-278-0 (Print); 978-1-80592-277-3 (Online)

    Curwyn Mapaling*

    Journal of Psychology in Africa, Vol.36, No.2, pp. 309-310, 2026, DOI:10.32604/jpa.2026.083289 - 29 April 2026

    Abstract This article has no abstract. More >

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