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  • Open Access

    ARTICLE

    A Tense Race: Correlation of Liver Stiffness with Ultrasound Elastography and Hemodynamics in Fontan Patients

    Yuen Lo Yau1, Matthew S. Purlee2, Lindsey M. Brinkley2, Dipankar Gupta1, David M. Saulino3, Dalia Lopez-Colon1, John-Anthony Coppola1, Dhanashree Rajderkar4, Himesh Vyas1,*

    Congenital Heart Disease, Vol.20, No.2, pp. 265-272, 2025, DOI:10.32604/chd.2025.065661 - 30 April 2025

    Abstract Background: Patients with Fontan physiology are predisposed to congestive hepatopathy, progressive liver fibrosis, and end-stage liver disease. Ultrasound-based shear wave elastography (SWE) is a non-invasive tool to diagnose and monitor liver fibrosis. We sought to determine whether the degree of hemodynamic derangement prior to and after the Fontan operation is associated with increased liver stiffness measured by SWE. Methods: A single-center retrospective study of patients with Fontan circulation who underwent ultrasound elastography between 2008 and 2024 was conducted. Liver stiffness was measured by SWE and reported as velocity in m/s. Hemodynamic assessment with cardiac catheterization and… More >

  • Open Access

    ARTICLE

    UltraSegNet: A Hybrid Deep Learning Framework for Enhanced Breast Cancer Segmentation and Classification on Ultrasound Images

    Suhaila Abuowaida1,*, Hamza Abu Owida2, Deema Mohammed Alsekait3,*, Nawaf Alshdaifat4, Diaa Salama AbdElminaam5,6, Mohammad Alshinwan4

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 3303-3333, 2025, DOI:10.32604/cmc.2025.063470 - 16 April 2025

    Abstract Segmenting a breast ultrasound image is still challenging due to the presence of speckle noise, dependency on the operator, and the variation of image quality. This paper presents the UltraSegNet architecture that addresses these challenges through three key technical innovations: This work adds three things: (1) a changed ResNet-50 backbone with sequential 3 convolutions to keep fine anatomical details that are needed for finding lesion boundaries; (2) a computationally efficient regional attention mechanism that works on high-resolution features without using a transformer’s extra memory; and (3) an adaptive feature fusion strategy that changes local and… More >

  • Open Access

    ARTICLE

    Blade Cutting Influence on Centrifugal Pump Noise Reduction

    Tianpeng Li1,*, Yujun Duan2, Qianghu Ji3

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.3, pp. 623-644, 2025, DOI:10.32604/fdmp.2024.053862 - 01 April 2025

    Abstract A centrifugal pump with a specific speed ns = 67 is considered in this study to investigate the impact of blade cutting (at the outlet edge) on the fluid-induced noise, while keeping all the other geometric parameters unchanged. The required unsteady numerical calculations are conducted by applying the RNG k-ε turbulence model with the volute dipole being used as the sound source. The results indicate that the internal pressure energy of the centrifugal pump essentially depends on the blade passing frequency and its low-frequency harmonic frequency. Moreover, the pressure pulsation distribution directly affects the noise caused More >

  • Open Access

    REVIEW

    A Comprehensive Review of Natural Rubber Composites: Properties, Compounding Aspects, and Renewable Practices with Natural Fibre Reinforcement

    Mohamad Firdaus Omar1, Fathilah Ali1,*, Mohammed Saedi Jami1, Azlin Suhaida Azmi1, Farah Ahmad1, Mohd Zahid Marzuki2, Shantha Kumari Muniyandi3, Zuraidah Zainudin4, Minsoo P. Kim5

    Journal of Renewable Materials, Vol.13, No.3, pp. 497-538, 2025, DOI:10.32604/jrm.2024.057248 - 20 March 2025

    Abstract This review provides a comprehensive overview of natural rubber (NR) composites, focusing on their properties, compounding aspects, and renewable practices involving natural fibre reinforcement. The properties of NR are influenced by the compounding process, which incorporates ingredients such as elastomers, vulcanizing agents, accelerators, activators, and fillers like carbon black and silica. While effective in enhancing properties, these fillers lack biodegradability, prompting the exploration of sustainable alternatives. The potential of natural fibres as renewable reinforcements in NR composites is thoroughly covered in this review, highlighting both their advantages, such as improved sustainability, and the challenges they More > Graphic Abstract

    A Comprehensive Review of Natural Rubber Composites: Properties, Compounding Aspects, and Renewable Practices with Natural Fibre Reinforcement

  • Open Access

    ARTICLE

    Ultrasound genomics related mitochondrial gene signature for prognosis and neoadjuvant chemotherapy resistance in triple negative breast cancer

    HUAFANG HUANG1,2,#, GUILIN WANG3,#, DONGYUN ZENG4,5, LUZ ANGELA TORRES-DE LA ROCHE2, RUI ZHUO1,2, RUDY LEON DE WILDE2, WANWAN WANG6, ULF D. KAHLERT7,*, WENJIE SHI7,*

    Oncology Research, Vol.33, No.3, pp. 631-640, 2025, DOI:10.32604/or.2024.054642 - 28 February 2025

    Abstract Background: Neoadjuvant chemotherapy (NAC) significantly enhances clinical outcomes in patients with triple-negative breast cancer (TNBC); however, chemoresistance frequently results in treatment failure. Consequently, understanding the mechanisms underlying resistance and accurately predicting this phenomenon are crucial for improving treatment efficacy. Methods: Ultrasound images from 62 patients, taken before and after neoadjuvant therapy, were collected. Mitochondrial-related genes were extracted from a public database. Ultrasound features associated with NAC resistance were identified and correlated with significant mitochondrial-related genes. Subsequently, a prognostic model was developed and evaluated using the GSE58812 dataset. We also assessed this model alongside clinical factors… More >

  • Open Access

    ARTICLE

    Partial gland ablation with high intensity focal ultrasound impact on genito-urinary function and quality of life: our initial experience

    Ioana Fugaru1, David Bouhadana1, Gautier Marcq2,3, Joseph Moryousef4, Alexis Rompré-Brodeur1, Andrew Meng4, Oleg Loutochin1, George Loutochin1, Maurice Anidjar1, Frank Bladou5, Rafael Sanchez-Salas1

    Canadian Journal of Urology, Vol.31, No.1, pp. 11784-11793, 2024

    Abstract Introduction: Partial gland ablation (PGA) using high intensity focal ultrasound (HIFU) is an alternative to active surveillance for low to intermediate risk localized prostate cancer. This pilot study assessed quality of life (QoL) outcomes during the implementation of PGA HIFU at our institution.
    Materials and methods: We prospectively enrolled 25 men with a diagnosis of localized low/intermediate risk prostate cancer who elected to undergo PGA-HIFU in a pilot study at our institution between 2013 and 2016. Patients underwent pre-treatment mpMRI and transrectal ultrasound-guided biopsies. The primary endpoints were impact on patient-reported functional outcomes (erectile, urinary function, QoL)… More >

  • Open Access

    RESIDENT’S CORNER

    Hand, foot, and mouth disease presenting with a testicular mass in an adult

    Sarah Azari, Darcy Wolfman2, Armine Smith3

    Canadian Journal of Urology, Vol.31, No.2, pp. 11854-11857, 2024

    Abstract The majority of solid testicular tumors are treated with orchiectomy given the high risk of malignancy. We present a case of a testicular mass in an adult patient in the setting of recent hand, foot, and mouth disease that was managed conservatively with serial ultrasounds. Even though cases of viral-associated testicular masses are rare, this differential diagnosis should be considered in patients with a new testicular mass in the setting of recent viral infection and negative tumor markers. For these patients, observation may be an option instead of immediate orchiectomy. More >

  • Open Access

    ARTICLE

    A costing and health-related quality of life study of high intensity focused ultrasound in primary treatment of localized low or intermediate risk prostate cancer in Ontario

    Bassem Toeama1, Nathan Perlis2, Paul Grootendorst1, William Orovan3, Emmanuel Papadimitropoulos1,4

    Canadian Journal of Urology, Vol.31, No.4, pp. 11963-11970, 2024

    Abstract Introduction: Prostate cancer is the third leading cause of death from cancer among Canadian men. High intensity focused ultrasound (HIFU) is a novel approach for primary treatment of localized prostate cancer. Little is known, however, about its costs. We aimed to collect the direct costs and health-related quality of life (HRQoL) data of HIFU in primary treatment of localized low and intermediate risk prostate cancer in Ontario.
    Materials and methods: We collected direct costs and HRQoL data of 20 patients with localized low or intermediate risk prostate cancer who received whole gland HIFU at a privately owned… More >

  • Open Access

    ARTICLE

    Bioactive Compounds Recovery from Larrea tridentata by Green Ultrasound-Assisted Extraction

    Muyideen Olaitan Bamidele1, José Sandoval-Cortés1, María Liliana Flores-López2, Olga Berenice Álvarez Pérez1, Monica Lizeth Chavez González1, Cristóbal Noe Aguilar1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 3091-3107, 2024, DOI:10.32604/phyton.2024.058422 - 30 November 2024

    Abstract Postharvest losses remain a significant challenge, particularly in developing countries that have inadequate infrastructure. Medicinal plants offer an eco-friendly and sustainable solution for managing diseases and pests in agricultural systems. These plants are rich in bioactive compounds, such as alkaloids, flavonoids, terpenoids, phenolics, and essential oils, many of which have proven antimicrobial, antifungal, insecticidal, and antioxidant properties. These characteristics make medicinal plants viable candidates for postharvest disease and pest control. Among these, Larrea tridentata (creosote bush) is particularly notable for its bioactive compounds with strong antifungal properties. Their potential applications include agriculture, food preservation, and medicine.… More > Graphic Abstract

    Bioactive Compounds Recovery from <i>Larrea tridentata</i> by Green Ultrasound-Assisted Extraction

  • Open Access

    PROCEEDINGS

    Design of 3D Printable Microlattices for Sound Absorption

    Xinwei Li1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.2, pp. 1-2, 2024, DOI:10.32604/icces.2024.011083

    Abstract The emergence of 3D printing opens new possibilities for the development of advanced and innovative metamaterials, particularly in the realm of microlattices. Microlattices are characterized as periodic cellular solids with submillimeter-sized features, such as struts, shells, or plates, arranged spatially in a three-dimensional way. Herein, based on four published studies, we provide a perspective on the design, employing analytical and numerical methods, as well as the performance of 3D-printed microlattices for sound absorption.
    The first study focuses on face-centered cubic-based plate and truss structures [1]. Impedance tube measurements reveal that all the microlattices display absorption curves… More >

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