Su Ye¹, Luxi Guan¹, Dong Luo¹, Fengwen Zhang¹, Jianhua Lv¹, Qizong Xie², Qiao Huang², Haiming Wu², Haibo Hu^1,*, Xiangbing Pan^1,*

Congenital Heart Disease, Vol.20, No.2, pp. 181-193, 2025, DOI:10.32604/chd.2025.063297 - 30 April 2025

Abstract Objectives: This study aimed to evaluate the feasibility, safety, and efficacy of a novel transcatheter suture closure system (HaloStitch^®) for patent foramen ovale (PFO) closure in a swine model. Methods: Thirteen swine underwent experimental PFO model creation. All animals received implantation of the transcatheter suture closure system to evaluate procedural success. Comprehensive follow-up over six months included serial ultrasound imaging, histopathological analysis, and gross anatomical examination of cardiac specimens. Results: Successful HaloStitch^® device implantation was achieved in 11 of 13 swine. Gross anatomical examination confirmed secure positioning of all sutures in the atrial septum, with no redundancy or… More >

Qing Wang, Luyao Cai, Shouyi Tang, Dan Pan, Zhen Wang, Qianming Chen, Yu Zhou^*, Yingqiang Shen^*

BIOCELL, Vol.49, No.4, pp. 579-605, 2025, DOI:10.32604/biocell.2025.060045 - 30 April 2025

Abstract Cancer Stem Cells (CSCs) are cancer cells with self-renewal and tumorigenesis abilities. CSCs in tumor tissues are the leading cause of tumor progression, recurrence, and drug resistance. CSCs have distinct metabolic features that contribute to maintaining their self-renewal and stemness. Phospholipids are essential components of cell membranes and play fundamental roles in cellular activities. CSCs have abnormal phospholipid metabolism, which affects their self-renewal, differentiation, invasion, and drug resistance. Compared with non-CSCs, the phospholipid metabolism of CSCs mainly focused on significantly increased fatty acid (FAs) and phospholipids synthesis, phospholipid unsaturation, and lipolysis-fatty acid oxidation (FAO). In More > Graphic Abstract

Yumei Lv¹, Wei Dai², Shupeng Xie¹, Peng Hu^1,*, Fei He^1,*

Frontiers in Heat and Mass Transfer, Vol.23, No.2, pp. 397-420, 2025, DOI:10.32604/fhmt.2025.062781 - 25 April 2025

Abstract Aiming at the global design issue of transpiration cooling thermal protection system, a self-driven circulation loop is proposed as the internal coolant flow passage for the transpiration cooling structure to achieve adaptive cooling. To enhance the universality of this internal cooling pipe design and facilitate its application, numerical studies are conducted on this system with four commonly used cooling mediums as coolant. Firstly, the accuracy of the numerical method is verified through an established experimental platform. Then, transient numerical simulations are performed on the flow states of different cooling mediums in the new self-circulation system. More >

Zhiyuan Zhang¹, Yongjun Wu¹, Xiqin Li¹, Minghui Song¹, Guangwu Zhang², Ziren Wang^3,*, Wei Li³

Energy Engineering, Vol.122, No.5, pp. 1919-1948, 2025, DOI:10.32604/ee.2025.063178 - 25 April 2025

Abstract The park-level integrated energy system (PIES) is essential for achieving carbon neutrality by managing multi-energy supply and demand while enhancing renewable energy integration. However, current carbon trading mechanisms lack sufficient incentives for emission reductions, and traditional optimization algorithms often face challenges with convergence and local optima in complex PIES scheduling. To address these issues, this paper introduces a low-carbon dispatch strategy that combines a reward-penalty tiered carbon trading model with P2G-CCS integration, hydrogen utilization, and the Secretary Bird Optimization Algorithm (SBOA). Key innovations include: (1) A dynamic reward-penalty carbon trading mechanism with coefficients (μ = 0.2,… More >

Arpita Johri^1,2,*, Varnita Verma³, Mainak Basu^1,*

Energy Engineering, Vol.122, No.5, pp. 1887-1918, 2025, DOI:10.32604/ee.2025.062355 - 25 April 2025

Abstract The globe faces an urgent need to close the energy demand-supply gap. Addressing this difficulty requires constructing a Hybrid Renewable Energy System (HRES), which has proven to be the most appropriate solution. HRES allows for integrating two or more renewable energy resources, successfully addressing the issue of intermittent availability of non-conventional energy resources. Optimization is critical for improving the HRES’s performance parameters during implementation. This study focuses on HRES using solar and biomass as renewable energy supplies and appropriate energy storage technologies. However, energy fluctuations present a problem with the power quality of HRES. To… More > Graphic Abstract

Linlan Chang¹, Win-Jet Luo^1,2, Indra Permana², Bowo Yuli Prasetyo³, Alya Penta Agharid¹, Fujen Wang^2,*

Energy Engineering, Vol.122, No.5, pp. 1771-1787, 2025, DOI:10.32604/ee.2025.062209 - 25 April 2025

Abstract Heating, Ventilation, and Air Conditioning (HVAC) systems are critical for maintaining thermal comfort in office environments which also crucial for occupant well-being and productivity. This study investigates the impact of integrating ceiling fans with higher air conditioning setpoints on thermal comfort and energy efficiency in office environments. Field measurements and questionnaire surveys were conducted to evaluate thermal comfort and energy-saving potential under varying conditions. Results show that increasing the AC setpoint from 25°C to 27°C, combined with ceiling fan operation, reduced power consumption by 10%, achieving significant energy savings. Survey data confirmed that 85% of… More >

Steffen Schedler^1,*, Michael Bareev-Rudy¹, Stefanie Meilinger², Tanja Clees^1,3

Energy Engineering, Vol.122, No.5, pp. 1755-1770, 2025, DOI:10.32604/ee.2025.061962 - 25 April 2025

Abstract Germany aims to achieve a national climate-neutral energy system by 2045. The residential sector still accounts for 29% of end energy consumption, with 74% attributed to the direct use of fossil fuels for heating and hot water. In order to reduce fossil energy use in the household sector, great efforts are being made to design new energy concepts that expand the use of renewable energies to supply electricity and heat. One possibility is to convert parts of the natural gas grid to a hydrogen-based gas grid to deliver and store energy for urban quarters of… More >

Danijel Pavković^*, Pietro Kristović, Mihael Cipek, Dragutin Lisjak

Energy Engineering, Vol.122, No.5, pp. 1669-1696, 2025, DOI:10.32604/ee.2025.061916 - 25 April 2025

Abstract In deep drilling applications, such as those for geothermal energy, there are many challenges, such as those related to efficient operation of the drilling fluid (mud) pumping system. Legacy drilling rigs often use paired, parallel-connected independent-excitation direct-current (DC) motors for mud pumps, that are supplied by a single power converter. This configuration results in electrical power imbalance, thus reducing its efficiency. This paper investigates this power imbalance issue in such legacy DC mud pump drive systems and offers an innovative solution in the form of a closed-loop control system for electrical load balancing. The paper… More > Graphic Abstract

Daixuan Zhou¹, Zhichao Wang¹, Kaile Xi², Chong Zuo³, Yan Jia^2,*

Energy Engineering, Vol.122, No.5, pp. 2119-2153, 2025, DOI:10.32604/ee.2025.061712 - 25 April 2025

Abstract HOMER (Hybrid Optimization Model for Electric Renewables) is an effective simulation and optimization platform for hybrid renewable energy. By inputting specific users’ energy resource data (such as wind speed, solar radiation, etc.) and load data, and by determining the types and models of components selected by the user, HOMER calculates and simulates the operational status of each component at every time step. Ultimately, it computes the energy balance of the system within specified constraints to simulate the overall system operation. This approach enables the reasonable determination of system component capacities, the evaluation of system feasibility,… More > Graphic Abstract

MOEKA NAKASHIMA, NAOKO SUGA, AKARI FUKUMOTO, SAYURI YOSHIKAWA, SATORU MATSUDA^*

Oncology Research, Vol.33, No.5, pp. 1007-1017, 2025, DOI:10.32604/or.2025.059657 - 18 April 2025

Abstract Malignant tumors are heterogeneous diseases characterized by uncontrolled cell proliferation, invasion, metastasis, and/or recurrence of their malignancies. In particular, cancer stem cells (CSCs) within these tumors might be responsible for the property of invasiveness and/or therapies-resistance. CSCs are a self-renewing, awfully tumorigenic subpopulation of cancer cells, which are notorious for strong chemoresistance and are frequently responsible the aggravated invasion, metastasis, and/or recurrence. Developing targeting therapies against CSCs, therefore, may be deliberated a more encouraging mission for the greater cancer therapy. Innovation for a more potent anti-CSC treatment has been required as soon as possible.… More > Graphic Abstract